All posts by Amber Dance

Looking ALS in the Eye

A simple eye test may help neurologists forecast prognosis, and even develop drugs for at least some neurological diseases. But what about ALS? Experts weigh in.

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Paper Alert: Could Antisense Therapy One Day Squelch Toxic Repeats in ALS or FTD?

If toxic RNAs are a problem, then antisense oligonucleotides (ASOs) appear to be a solution. In this case, the toxic RNAs are transcribed from hexanucleotide repeats in the C9ORF72 gene, which can cause both amyotrophic lateral sclerosis and frontotemporal dementia in people (see Sep 2011 news). Transgenic mouse models expressing these repeats develop the same […]

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