All posts by Alzforum, Gwyneth Dickey Zakaib

Grow that Axon: C9ORF72 Function Revealed?

While mutated C9ORF72 leads to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD), scientists still wonder what the healthy protein does. In the October 10 Nature Neuroscience online, scientists led by Michael Sendtner, University Hospital of Wuerzburg, Germany, suggest that the C9ORF72 protein modulates actin dynamics.

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Gene Links Childhood Neurodegeneration to Mitophagy

Neurodegenerative disease almost always strikes in adults, but some extremely rare forms can crop up in adolescents or even children. Genetic clues to abnormal pathways that underlie these early onset disorders might help scientists better understand late-onset diseases such as Alzheimer’s. A study in the September 1 American Journal of Human Genetics reports that rare […]

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