Dimethyl fumarate (Tecfidera)

Drug Name: Dimethyl fumarate (Tecfidera)
Company: Biogen
Location: Australia
Drug Type: Small molecule
Conditions: ALS, MS
Mechanism Type: Immunomodulation
Mechanism: Dimethyl fumarate may help protect neurons from further damage in at least some forms of MS by increasing the percentage of Tregs and improving their ability to regulate inflammation in the immune system.
U.S. Status for ALS: Phase II

References:
[1] Study to Assess the Efficacy and Safety of Tecfidera in Patients with Amyotrophic Lateral Sclerosis Australian New Zealand Clinical Trials Registry. Accessed 25 Jan 2019 from https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12618000534280.

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