Reldesemtiv (CK-2127107)

Drug Name: Reldesemtiv (CK-2127107)
Company: Cytokinetics
Location: US-California
Drug Type: Small Molecule
Conditions: ALS, SMA, and others
Mechanism Type: Improving muscle function
Mechanism: CK-107, is a fast skeletal muscle troponin activator (FSTA), that aims to increase muscle strength and decrease muscle fatigue in part, by slowing the release of calcium bound to the muscle protein, troponin, increasing the force of muscle contraction.
U.S. Status for ALS: Phase II

[1] A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS), 5 Feb 2018. Accessed 8 Feb 2018 from

Last updated February 8th, 2018

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