Techniques for generating neurons from stem cells derived from individual patients’ cells (induced pluripotent stem cells, iPSCs) have opened the doors for modeling, drug screening and development of personalized therapeutics in many diseases, including ALS (see May 2014 news story, April 2014 news story). In the December Stem Cells Translational Medicine, researchers led by Dhruv Sareen of Cedars-Sinai Medical Center in Los Angeles, California report on a new method for generating iPSCs from stored blood samples. This approach greatly expands the patient pool for studies in ALS and other rare diseases, as cell lines can be generated from deceased patients whose blood samples are stored in large biorepositories. Click here to read more.
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