Keystone 2015: Neuroinflammation in Diseases of the Central Nervous System

The fields of neuroscience and immunology melded into one at “Neuroinflammation in Diseases of the Central Nervous System,” a Keystone Symposium held January 25-30 in Taos, New Mexico. The behavior of myeloid cells in the brain drew close scrutiny at the conference, as researchers grappled with fundamental questions such as, what do microglia actually do, and how do they respond to and influence the course of neurodegenerative disease? Novel genomic and proteomic tools emerged that may help answer these questions. Researchers abandoned the old M1/M2 microglial phenotypes calling for more relevant characterizations, and embraced TREM2 and other molecules that play central roles in microglial responses.

Read Alzforum’s Jessica Shugart’s articles from the meeting:
Part I: Neuroinflammation Field Grapples With Complexity at Keystone Symposia
Part II: Nature vs. Nurture: What Gives Microglia Their Identity?
Part III: Microglia in Disease: Innocent Bystanders, or Agents of Destruction?

 


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conf-keystone disease-ad disease-als disease-ftd disease-ms microglia
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