P110

Drug Name: P110
Company: Mitoconix Bio
Website: http://www.futurx.co.il/portfolio/mitoconix-bio/
Drug Type: Protein Biologic
Conditions: ALS
Mechanism Type: Mitochondrial protectant
Mechanism: Restoring mitochondrial dynamics, by blocking the hyperactivation of the fission regulator Drp1, may help protect motor neurons in ALS by reducing oxidative stress and increasing energy levels, including at the nerve terminals.
U.S. Status for ALS: Preclinical

References:
[1] Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. Joshi, AU et al., 2018. EMBO Mol Med. 2018 Jan 15. pii: e8166.

Last updated February 14th, 2018

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