Neurturin

Drug Name: Neurturin
Company: N/A
Location: US-Maryland
Drug Type: Gene Therapy
Conditions: ALS, Parkinson’s disease
Mechanism Type: Neuroprotection
Mechanism: The approach aims to help protect motor neurons in ALS in part, by stimulating axonal outgrowth and protecting against glutamate-induced excitotoxicity.
U.S. Status for ALS: Preclinical

References:
[1] Intraspinal delivery of AAV2-NRTN for ALS – a dose-ranging study of safety, tolerability, biodistribution, and efficacy. Gross, SK et al. 2017 Meeting of the Society of Neuroscience.
[2] The ongoing pursuit of neuroprotective therapies in Parkinson disease. Athauda D, Foltynie T. Nat Rev Neurol. 2015 Jan;11(1):25-40.

Last updated February 15th, 2018

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