Figure 1B Amplitude of low frequency fluctuation  (ALFF) differences between ALS and control groups without grey matter (GM) correction (A) and with GM correction (B).
Image credit: Luo, et.al. 2012 under CC BY license

Job Opportunities

To submit any new job opportunities for this list, please email [email protected]. List the employer, location, closing date if applicable, and a link to more information. Jobs are removed after 3 months, unless requested otherwise.

This free job bulletin board aims to help scientists identify job opportunities in the field of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Positions described as broadly spanning neurodegenerative diseases (NDG) are noted as ‘NDG‘. The job listing includes research positions at all levels, as well as non-research positions for which a research background at the MS, PhD, or MD level is required.


Click the title of any table column to sort.

Academia

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
NEW! Research Technician, Suzuki Lab

Research Technician, Suzuki Lab

(Click title to open job details in a new window.)
Description:

Under the supervision of the PI (Masatoshi Suzuki) or staff scientists, the research specialist will conduct laboratory research related to neuromuscular disorders such as Amyotrophic Lateral Sclerosis (ALS) using human stem cells. The successful candidate will have an important role in the lab, both performing experiments independently and supporting the ongoing work of others.


Link: http://jobs.hr.wisc.edu/cw/en-us/job/498622/research-technician?source=IND
Employer: University of Wisconsin
Location: Madison, WI
Sector: Academia
Degree required: BS required, MS preferred
Conditions: ALS
Job posted: July 16th, 2018
Applications close: July 31st, 2018
University of WisconsinMadison, WIBS required, MS preferredALSJul 16, 2018
NEW! Assistant or Associate Professor, Neuroscience

Assistant or Associate Professor, Neuroscience

(Click title to open job details in a new window.)
Description:

The Department of Neuroscience at UConn Health invites highly motivated investigators addressing key questions in neurodevelopment, synaptic or cognitive dysfunction or neuroinflammation to apply for a tenure-track position at the Assistant or Associate Professor rank. We welcome candidates using the most advanced techniques in mouse genetics, system neurobiology, and electrophysiology. Candidates interested in deciphering disease etiology, molecular mechanisms or carrying out translational studies focused on neurodegenerative diseases, vascular dementia, neuroinflammatory disorders, or neural regeneration will complement the strengths of this department and are particularly encouraged to apply.


Applicants may apply at https://jobs.uchc.edu with their CV, cover letter, and a concise statement of their research and teaching interests, with the same documents also sent to [email protected]. Applicants should arrange to have at least three letters of reference sent to [email protected] as a .pdf document on letterhead with signature.


Link: https://neurojobs.sfn.org/jobs/11252930/assistant-professor-tenure-track-department-of-neuroscience
Employer: University of Connecticut
Location: Farmington, CT
Sector: Academia
Degree required: PhD and/or MD
Conditions: NDG
Job posted: July 12th, 2018
University of ConnecticutFarmington, CTPhD and/or MDNDGJul 12, 2018
NEW! Assistant Professor, Neuroimmunology

Assistant Professor, Neuroimmunology

(Click title to open job details in a new window.)
Description:

The McDonnell Center for Cellular & Molecular Neurobiology at Washington University School of Medicine invites applications for tenure track Assistant Professor positions. We are seeking talented investigators who will develop an innovative research program in any field within the area of fundamental and translational neuroimmunology. Investigators employing novel genomics and neurological diseases including, but not limited to neurodegenerative and demyelinating disorders, are encouraged to apply. Investigators will be supported by the McDonnell Center in collaboration with two of our outstanding departments—one preclinical and one clinical—at Washington University School of Medicine. Applicants should submit a cover letter, curriculum vitae, one-page summary of research accomplishments and one-page description of future research plans.


Applicants should submit a single PDF file that contains only a cover letter, curriculum vitae, one-page summary of research accomplishments, and one-page description of future research plans (in this order).


Applicants should request 3 letters of support to be e-mailed directly to [email protected]. Review of complete applications, including received letters of support, will begin on September 15, 2018.


Link: https://facultyopportunities.wustl.edu/apply/Posting/Detail/1010300
Employer: Washington University School of Medicine
Location: St Louis, MO
Sector: Academia
Degree required: PhD or MD/PhD
Conditions: NDG
Job posted: July 11th, 2018
Washington University School of MedicineSt Louis, MOPhD or MD/PhDNDGJul 11, 2018
NEW! Postdoctoral Fellow, Baker Lab

Postdoctoral Fellow, Baker Lab

(Click title to open job details in a new window.)
Description:

You will contribute to a major new project, funded by the William Leech Charity, to generate a primate model of motor neuron disease. You will be responsible for the day-to-day running of the project, gathering electrophysiological and imaging data. You will perform computational analysis of the data, and will produce the first draft of manuscripts to publish the results. A PhD in Neuroscience or related discipline is essential, and experience with primate electrophysiology, MRI, and writing MATLAB scripts for data analysis would be an advantage.


Excellent team skills are required to liaise with the many staff members with roles in this project, and a strong commitment to animal welfare and 3Rs.


The post is available fixed term until the end of March 2021.


Informal enquiries to [email protected]


Employer: Newcastle University
Location: Newcastle Upon Tyne, England
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: July 11th, 2018
Applications close: August 10th, 2018
Newcastle UniversityNewcastle Upon Tyne, EnglandPhDALSJul 11, 2018
NEW! Postdoctoral Fellow, Belzil Lab

Postdoctoral Fellow, Belzil Lab

(Click title to open job details in a new window.)
Description:

We are looking to hire a postdoctoral fellow holding a PhD in Bioinformatics or Genetics/Epigenetics with strong expertise in next-generation sequencing (NGS) data analysis to lead the bioinformatic component of our research program. That person will be proficient in C++, Java, Python, R and unix environments, including supercomputing applications. Optimally, the recruited person will also have expertise in conducting statistical analyses and algorithm development. The individual needs to be independent and motivated to perform genomic, epigenomic and transcriptomic analyses — the primary mentor will be Dr. Veronique Belzil and a bioinformatics professor will be available for guidance.


The Belzil Laboratory aims to identify genomic/epigenomic/transcriptomic mediators of neurodegeneration and evaluate their potential as biomarkers and therapeutic targets for amyotrophic lateral sclerosis (ALS) and other related diseases. Specifically, using state-of-the-art integrative multi-omics bioinformatic and system biology approaches, her laboratory aims to (1) better understand genome-epigenome-transcriptome interactions leading to ALS; (2) develop clinically relevant and scalable ALS-specific biomarker panels to guide more tailored management of ALS patients; (3) inform the next generation of individualized clinical trials for ALS; (4) identify key pathological pathways and genetic & epigenetic modifiers of transcription mediating neurodegeneration susceptibility that can be targeted by therapeutics; (5) generate results that can quickly be translated from bench to bedside: we want to quickly impact clinical practice and promote individualized medicine and (6) promote collaborative efforts — collaborations and team work is essential to finding a cure for ALS.


To apply, contact Veronique Belzil.


Employer: Mayo Clinic
Location: Jacksonville, FL
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: July 9th, 2018
Mayo ClinicJacksonville, FLPhDALSJul 09, 2018
Associate or Full Professor, Pharmacology

Associate or Full Professor, Pharmacology

(Click title to open job details in a new window.)
Description:

The Department of Pharmacology & Toxicology and the Stark Neurosciences Research Institute (SNRI) at the Indiana University of Medicine in Indianapolis invites applications from outstanding individuals for the Stark Professorship at the Associate or Full Professor level. A Ph.D. and/or M.D. degree and tenure track faculty experience are required. Preference will be given to individuals with outstanding scholarship in the fields of neuropharmacology and neuroscience. Competitive start-up packages include ample laboratory space and access to exceptional core research facilities. The successful candidate will have a strong record of publications and peer-reviewed funding as a principal investigator in the field of neuropharmacology as it relates to neuroimmunology, translational neuroscience, and neurodegenerative disease. The scientific environment at the School of Medicine, the Department of Pharmacology and Toxicology, and the SNRI is highly interactive and productive with ties on campus to other Basic Science and Clinical Departments, as well as Research Centers and Institutes. Outstanding core facilities are also available. Interested candidates should upload a cover letter, curriculum vitae, description of research goals, with names and contact information for three references at: http://indiana.peopleadmin.com/postings/4337


Link: https://indiana.peopleadmin.com/postings/4337
Employer: Indiana University
Location: Indianapolis, IN
Sector: Academia
Degree required: PhD and/or MD
Conditions: NDG
Job posted: July 5th, 2018
Indiana UniversityIndianapolis, INPhD and/or MDNDGJul 05, 2018
Research Assistant, Hardiman Lab

Research Assistant, Hardiman Lab

(Click title to open job details in a new window.)
Description:

Applications are invited for a motivated and self-driven individual for the position of research assistant with the Irish ALS Research Group, hosted in the Trinity Biomedical Sciences Institute (TBSI) Academic Unit of Neurology. The ideal candidate will have an undergraduate or Master’s degree in engineering, bioengineering, mathematics, physics, computational biology, or a cognate area. Familiarity with and/or the ability to quickly acquire skills in electrophysiological recordings and analysis (e.g. EEG/EMG), would be highly desirable as would a knowledge of computer programming (MATLAB).


Link: https://www.universityvacancies.com/trinity-college-dublin/research-assistant-neural-engineering-9905
Employer: Trinity College Dublin
Location: Dublin, Ireland
Sector: Academia
Degree required: Applicants should hold a minimum upper-second class (2:1) honours degree (or equivalent) in engineering, bioengineering, physics, (computational) neuroscience, neurophysiology, physics, mathematics, or a related area.
Conditions: ALS
Job posted: July 3rd, 2018
Applications close: July 24th, 2018
Trinity College DublinDublin, IrelandApplicants should hold a minimum upper-second class (2:1) honours degree (or equivalent) in engineering, bioengineering, physics, (computational) neuroscience, neurophysiology, physics, mathematics, or a related area.ALSJul 03, 2018
Associate Professor, Neuroscience

Associate Professor, Neuroscience

(Click title to open job details in a new window.)
Description:

The Department of Neuroscience at Mayo Clinic in Jacksonville, Florida is seeking outstanding candidates with dynamic research programs in Neurobiology of Disease and Aging.


The candidates for this position will be expected to have a track record of major contributions to the field, with an emphasis on the application of novel in vitro and in vivo imaging tools, disease modeling using animals and induced pluripotent stem cells, the use of systems level analytical and bioinformatics approaches, or the integration of multiple discovery platforms to advance our understanding of disease biology and etiology. Although all areas of neurodegenerative disease and aging research will be considered, we are particular seeking candidates who have primary interests in Alzheimer’s disease and related dementias, synaptic biology, innate immunity, vascular biology, and brain aging as it relates to neurobiology of disease. The candidates for this position are expected to have a history of extramural funding, as well as a proven record of collaborative team science endeavors. Individuals with interest and experience in research training and graduate-level education are particularly encouraged to respond.


The Mayo Clinic Department of Neuroscience is a prominent department and is internationally recognized and respected for academic excellence. Basic scientists within the neuroscience department have strong expertise in neurogenetics, neuropathology, disease modeling, immunity, and experimental therapeutics. The Department faculty play key roles in the Alzheimer’s Disease Research Center, large scale NIA-funded Alzheimer’s disease consortia including AMP-AD and M2OVE-AD, Tau Center without Walls, biomarker studies of Lewy body dementia and in NIH whole genome sequencing studies of both


frontotemporal dementia and the parkinsonian tauopathy progressive supranuclear palsy. The research mission of the department is closely aligned with the resources and initiatives of the Center for Biomedical Discovery, Center for Regenerative Medicine, Center for Individualized Medicine, Department of Neurology, Department of Neurosurgery, and the Center on Aging. The Department also has an outstanding training environment and is closely aligned with the Neurobiology of Disease Program at Mayo Clinic Graduate School of Biomedical Sciences, the Mayo Clinic School of Medicine and the Mayo Clinic School of Graduate Medical Education.


Mayo Clinic has a large number of world-class
faculty. Laboratories and shared resource facilities are state-of- the-art, including those for microscopy and imaging, cell and molecular biology, animal models, production of iPS cells and clinical grade MSCs, biomedical engineering and mathematics, materials testing, a Medical Genomics Facility, a Mouse Modeling Facility, Molecular and Microscopic Core Facilities, and unique Human Disease Tissue Banks. We offer a highly competitive compensation package with sustained intramural funding, capital equipment funding, technical and computational resources, and exceptional benefits.


Applications should include a cover letter, CV and a statement of research interests. Specific questions should be directed to: Dr. Leonard Petrucelli, Ph.D. Department of Neuroscience Chair, Search Committee C/O Adriana Semko [email protected]


Link: https://jobs.sciencecareers.org/job/482805/faculty-positions-department-of-neuroscience/
Employer: Mayo Clinic
Location: Jacksonville, FL
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: July 2nd, 2018
Mayo ClinicJacksonville, FLPhDNDGJul 02, 2018
Postdoctoral Fellow, Bhattacharya Lab

Postdoctoral Fellow, Bhattacharya Lab

(Click title to open job details in a new window.)
Description:

The Department of Neuroscience has an opening for a qualified and highly motivated Postdoctoral Research Associate. The successful candidate will join Dr. Martha Bhattacharya’s laboratory which is focused on the molecular and cellular study of nerve damage responses in both mice and Drosophila (fruit flies). The long-term goal of our research is to identify ways to delay or prevent the degeneration of axons in neurodegenerative diseases, thus preserving nerve function. Candidates who are eligible to compete for postdoctoral funding, such as the NIH Ruth L Kirschstein Institutional National Service Awards (NRSA), are strongly preferred.


To apply for this position, submit a cover letter and curriculum vitae online: https://uacareers.com/postings/29995.


To learn more about this position, contact Martha Bhattacharya.


Link: https://uacareers.com/postings/29995
Employer: University of Arizona
Location: Tucson, AZ
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: July 2nd, 2018
University of ArizonaTucson, AZPhDALSJul 02, 2018
Research Associate

Research Associate

(Click title to open job details in a new window.)
Description:

We are currently recruiting for a Research Associate I with some basic computational skills and/ or cell culture experience with the desire to learn and work on a multi-faceted project with diverse roles. The person in this position will work with iPSC from patients with Amyotrophic Lateral Sclerosis with the goal to elucidate molecular mechanisms of ALS and to help devlop platforms for drug discovery.


This person will preform some cell culture work induced pluripotent stem cells from ALS patients to generate motor or cortical i-neurons and will subject them to our novel robotic microscopy (RM) system. In addition, this person will help to run and develop some of our image analysis based programs to capture phenotypes. At the core of our research is a novel RM system that we have invented to collect images and time-lapse movies of fluorescently-labeled neurons in high throughput format. We use our microscopy system to extract various types of biological information about how patient stem cell derived neurons grow and respond to candidate drugs. Some ICC, QRT-PCR and cell culture with other cells types may also be part of duties. We have collaborations with many industry and academic groups, publish our work in high profile scientific journals, and present our work at international conferences.


Link: https://careers-gladstone.icims.com/jobs/1487/research-associate-i/job?mode=job&iis=Job+Board+-+Indeed.com&iisn=Indeed.com&mobile=false&width=990&height=500&bga=true&needsRedirect=false&jan1offset=-300&jun1offset=-240
Employer: Gladstone Institutes
Location: San Francisco, CA
Sector: Academia
Degree required: MS (preferred)
Conditions: ALS
Job posted: July 2nd, 2018
Gladstone InstitutesSan Francisco, CAMS (preferred)ALSJul 02, 2018
Postdoctoral Fellow, Bertolotti Lab

Postdoctoral Fellow, Bertolotti Lab

(Click title to open job details in a new window.)
Description:

We are looking for a post-doctoral scientist to join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consist in selective inhibition of phosphatases, an important discovery because phosphatases were thought to be undruggable before this work (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716).


You will join a strong inter-disciplinary team at the LMB, which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases. We also have an excellent record of innovative basic research leading to applications in medicine.


You will make a significant contribution to a project aimed at capitalizing on our pioneering discoveries on phosphatases and assess the therapeutic potential of newly discovered inhibitors in diverse mouse models of neurodegenerative diseases.


You will have a PhD molecular biology or due to complete doctoral studies within 6 months of applying. Relevant experience is required and this must be best attested by at least one impactful publication. Experience working with mice and conducting behavioral and molecular studies in mice is essential. Experience with neurodegenerative diseases and having an interest in chemical biology, signaling and/or stress responses/protein quality control is desirable.


You will enjoy interacting with a dynamic interdisciplinary team sharing a passion for science and a commitment to explore the unknown.


The successful candidate will be awarded a three-year MRC Career Development Fellowship/MRCPostdoctoral Training Scheme, which is a training and development position for a postdoctoral scientist who has recently completed doctoral studies or is moving into a new research discipline.


To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7cc8_dfa8ad6b-8b10-4afd-81a6-42c3dbf9b037/candidate/postings/977. If you are unable to apply online please contact us at [email protected].


Further information about the position may be obtained from Dr Anne Bertolotti ([email protected])


Link: https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7cc8_dfa8ad6b-8b10-4afd-81a6-42c3dbf9b037/candidate/postings/977
Employer: MRC Laboratory of Molecular Biology
Location: Cambridge, England
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: June 30th, 2018
Applications close: July 30th, 2018
MRC Laboratory of Molecular BiologyCambridge, EnglandPhDALSJun 30, 2018
Assistant, Associate or Full Professor, Chemical Biology

Assistant, Associate or Full Professor, Chemical Biology

(Click title to open job details in a new window.)
Description:

Indiana University School of Medicine is seeking applications for tenure-track faculty positions at the Assistant/Associate/Full Professor levels in the basic science areas of chemical biology, metabolism and neuroscience. A key part of a Program in Chemical Biology of the School’s Precision Health Initiative (PHI), this search is also aligned with the Department of Biochemistry & Molecular Biology (BIOM), Stark Neuroscience Research Institute (SNRI) and NIH-designated Center for Diabetes and Metabolic Diseases (CDMD). Applications are welcome from all areas of chemical biology, however, applications with a molecular and/or pharmacological research emphasis in areas such as metabolism\insulin resistance\islet biology and neurodegenerative disease states are highly encouraged. A primary appointment for successful applicants may be based in any of these units as appropriate to the credentials and goals of the candidate.


Interested individuals should submit a Curriculum Vitae, cover letter, summary of past accomplishments and future research plans, and the names and contact information for 3-5 references in electronic format. The search committee will begin considering applications immediately and on an on-going basis until positions are filled.


Link: https://main.hercjobs.org/jobs/11216646/assistant-associate-full-professor-precision-health-initiative
Employer: Indiana University
Location: Indianapolis, IN
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 29th, 2018
Indiana UniversityIndianapolis, INPhDNDGJun 29, 2018
Postdoctoral Fellow, Roberson Lab

Postdoctoral Fellow, Roberson Lab

(Click title to open job details in a new window.)
Description:

Postdoctoral fellowships are available in the laboratory of Dr. Erik Roberson (www.uab.edu/roberson) to study molecular pathogenesis of neurodegenerative disorders. Our work focuses on the neurobiology of Alzheimer’s disease and frontotemporal dementia using mouse and cell models, with an emphasis on questions of translational importance. Multiple fully funded positions are available immediately, working in areas including tau, hyperexcitability, and interneuron dysfunction in Alzheimer’s disease and progranulin gene therapy for frontotemporal dementia.


The lab is a dynamic and interactive group, based within one of the leading neurodegeneration research institutes, the highly collaborative Center for Neurodegeneration and Experimental Therapeutics at UAB. Prior fellows in the lab have been successful in obtaining both academic faculty and industry positions as well as independent funding including the K99/R00 Pathway to Independence Award.


Candidates must possess a Ph.D., M.D., or both, and should be highly motivated, creative, and productive, with excellent oral and written communication skills. A strong publication record is important. Expertise with mouse models, stereotaxic surgery, EEG, and/or synaptic physiology in slice preparations is particularly desirable.


Please send Curriculum Vitae, statement of research interests, and the names and contact information for three references to Dr. Roberson, [email protected].


Link: http://uab.edu/roberson
Employer: University of Alabama
Location: University of Alabama
Sector: Academia
Degree required: PhD
Conditions: FTD
Job posted: June 27th, 2018
Applications close: August 26th, 2018
University of AlabamaUniversity of AlabamaPhDFTDJun 27, 2018
Assistant Professor, Neuroscience

Assistant Professor, Neuroscience

(Click title to open job details in a new window.)
Description:

The Program in Neuroscience and Behavior at Mount Holyoke College invites applications for a full-time tenure-track assistant professor in systems neuroscience beginning July 1, 2019. The successful candidate will demonstrate the ability to build a rigorous program of high quality research that integrally involves the contributions of undergraduate students. Research interests across the discipline of neuroscience are welcome and may include vertebrate and invertebrate models, or computational approaches. We also seek candidates with a strong commitment to undergraduate education who will teach 4 courses per year, which may include an introductory course, the development of an intermediate neuroscience course, and upper-level laboratory and seminar courses in the candidate’s area of expertise.


Mount Holyoke supports faculty scholarship through competitive start-up funds, travel support, internal grants, and a generous sabbatical policy. Newly renovated laboratory spaces are available to accommodate mammalian and non-mammalian model organisms. Mount Holyoke also offers a comprehensive faculty mentoring program and invests in faculty across their career span. All candidates should have a doctorate at the time of application; postdoctoral experience is preferred.


Applications must be made online at https://jobs.mtholyoke.edu by submitting a cover letter, a CV and statements on the following: (1) teaching philosophy, (2) research plans, and (3) mentoring a diverse student body. Applicants should also arrange to have three letters of reference submitted on their behalf. Electronic prompts to referees will be generated automatically after the completed application has been submitted. Review of applications will begin on August 31, 2018 and continue until the position is filled.


Link: https://careers.insidehighered.com/job/1562432/assistant-professor-of-neuroscience-and-behavior/
Employer: Mount Holyoke College
Location: South Hadley, MA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 25th, 2018
Mount Holyoke CollegeSouth Hadley, MAPhDNDGJun 25, 2018
Assistant, Associate or Full Professor, Pathology

Assistant, Associate or Full Professor, Pathology

(Click title to open job details in a new window.)
Description:

The Department of Pathology (http://pathology.ucsd.edu) at the University of California San Diego seeks exceptional scientists with neurodegeneration research programs for a faculty position(s).


The appropriate series and appointment at the Assistant, Associate or Full Professor level will be based on the candidate’s qualifications and experience. Salary is commensurate with qualifications and based on the University of California pay scales. Appointments may require candidates to be self-funded.


A link to full descriptions of each series is provided for your review:


HS Clinical Professor – see: http://www.ucop.edu/academic-personnel-programs/_files/apm/apm-278.pdf

Clinical X Professor – see: http://www.ucop.edu/academic-personnel-programs/_files/apm/apm-275.pdf

Adjunct Professor – see: http://ucop.edu/academic-personnel-programs/_files/apm/apm-280.pdf

In-Residence Professor – see: http://www.ucop.edu/academic-personnel-programs/_files/apm/apm-270.pdf


Candidates must have an MD and/or PhD degree in relevant areas of neurosciences and pathology, a demonstrated track record of scholarly achievement and research excellence. Candidates must also have an innovative research focus in neurodegeneration.


Applications must be submitted through the University of California San Diego’s Academic Personnel RECRUIT system at: https://apol-recruit.ucsd.edu/apply/JPF01809.


Link: http://apptrkr.com/1243563
Employer: University of California
Location: San Diego, CA
Sector: Academia
Degree required: MD and/or PhD
Conditions: NDG
Job posted: June 20th, 2018
University of CaliforniaSan Diego, CAMD and/or PhDNDGJun 20, 2018
Assistant Professor, Computational Clinical Neuroscience

Assistant Professor, Computational Clinical Neuroscience

(Click title to open job details in a new window.)
Description:

The Department of Psychology at Tufts University is seeking applicants at the assistant professor level for a tenure-track position in computational clinical neuroscience to begin September 1, 2019. The successful candidate will have a Ph.D. (or be ABD) and an active research program capable of supporting extramural funding. Area of specialization is open, but candidates should use mathematical and computational modeling approaches (e.g., Bayesian, connectionist, reinforcement learning) and/or data science approaches in their research; candidates with research interests that bridge to those of other members of the department are of particular interest. Potential research areas might include, but are not limited to, characterizing core computational and/or neural network disruptions underlying psychological disorders; identifying neural markers that predict mental health problems and/or treatment response; testing predictions developed from computational models of basic perceptual, cognitive, or affective mechanisms in clinical populations; and applying advanced analytic approaches (e.g., multivariate analysis, machine learning) to complex neuroimaging datasets (including fMRI, EEG/ERP, and MEG).


The successful candidate will utilize methods and ask questions that can contribute to the university’s new Data Intensive Studies Center (or DISC, see http://viceprovost.tufts.edu/data-intensive-study-center/). Applicants should be interested in teaching introductory, advanced, and quantitatively-oriented courses that will contribute to our undergraduate majors in Biopsychology, Clinical Psychology, and Cognitive & Brain Sciences; to our Ph.D. graduate programs in Experimental Psychology and Cognitive Science; and to the new degree programs within the DISC. Teaching load would be four courses per year or the equivalent, with opportunities for workload-related reductions.


Applicants should submit via Interfolio (https://apply.interfolio.com/51438) the following materials: a one-page cover letter discussing their potential contributions to the department and to the DISC initiative at Tufts; a C.V.; a statement of research accomplishments and future plans (note that our department embraces open and reproducible science, and candidates are encouraged to address how they pursue these goals in their work); a statement of teaching experience and approach; three letters of recommendation which should be uploaded by recommenders directly to the Interfolio site; copies of representative scholarly work (no more than three); and a brief diversity statement that describes the candidate’s aspirations and potential for promoting diversity and inclusion in their professional career. Inquiries should be emailed to Department Manager Jessica Storozuk ([email protected]).


Review of applications will begin October 1, 2018, and will continue until the position is filled.


Link: https://apply.interfolio.com/51438
Employer: Tufts University
Location: Medford, MA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 19th, 2018
Tufts UniversityMedford, MAPhDNDGJun 19, 2018
Research Assistant, Fisher Lab

Research Assistant, Fisher Lab

(Click title to open job details in a new window.)
Description:

We are seeking a research assistant, ideally already skilled in the molecular cloning techniques required for gene targeting in the mouse. The post-holder will support a new group at MRC Harwell and the Senior Investigator Scientist who will run this group, in collaboration with Professor Elizabeth Fisher at UCL, to make gene targeted mouse models for studying neurodegeneration.


This is an exciting and challenging position. The post-holder will be part of a larger Harwell – UCL Institute of Neurology group studying neurodegeneration, and will work with full support from the various services offered by MRC Harwell and at UCL. The candidate must have an interest in the technicalities of genome engineering and the biology of neurodegenerative disease.


The salary: £22,201 – £25,976.


Applications will be accepted on the MRC Harwell website until July 8, 2018.


Link: https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/955
Employer: MRC Harwell Institute
Location: Harwell, England
Sector: Academia
Degree required: BSc
Conditions: NDG
Job posted: June 13th, 2018
MRC Harwell InstituteHarwell, EnglandBScNDGJun 13, 2018
Postdoctoral Fellow, Patsopoulos Lab

Postdoctoral Fellow, Patsopoulos Lab

(Click title to open job details in a new window.)
Description:

The Patsopoulos Laboratory at the Ann Romney Center of Neurological Diseases (ARCND), Brigham & Women’s Hospital and Harvard Medical School is seeking a highly-motivated post-doctoral fellow to be part of a leading team that aims to unravel the mechanisms of neurodegenerative and autoimmune diseases.


The Patsopoulos Lab, headed by Nikolaos Patsopoulos, M.D., Ph.D., is leading large-scale efforts to decipher the genetic component of neurodegenerative and autoimmune diseases and specializes in integrating extensive heterogeneous data to inform personalized decision-making. The group uses in-house and publicly available data for the unbiased identification of key genes and pathways; it also designs avant-garde experimental procedures to create cell-specific and patient-specific response networks. The group collaborates closely with teams in the ARCND, Brigham & Women’s Hospital, and the Broad Institute of MIT and Harvard.


We are looking for one (1) post-doctoral fellow to join our group and work on large-scale RNA-seq and other sequencing based data. Expert knowledge in one or more of the following areas would be considered an advantage:


1) Analysis of next-generation sequencing, including but not limited to RNA-Seq, small RNA-Seq, GRO-Seq, Chip-Seq, and/or proteomic datasets.

2) Systems biology and/or integration of multi-omic data, with an emphasis in methods using summary statistics.

3) Track record in C/C++ and parallel computing (GPUs/Xeon Phis) will be prioritized.


The candidates should have demonstrated excellent scientific productivity, evidenced by high-quality research publications, and be able to conduct independent creative research, as well as show good inter-personal and communication skills. Excellent skills in scripting, e.g. Python, and statistical languages, e.g. R, are prerequisite. Ph.D., M.D. or equivalent degree is required for all positions.


To apply, please email your CV, cover letter summarizing your experience, and the contact information of three references to [email protected], addressed to Nikolaos Patsopoulos M.D., Ph.D., Assistant Professor of Neurology and Genetics.


Link: https://www.nature.com/naturejobs/science/jobs/646221-post-doctoral-fellow-in-the-patsopoulos-lab-brigham-and-women-s-hospital-harvard-medical-school
Employer: Brigham and Women's Hospital
Location: Boston, MA
Sector: Academia
Degree required: PhD, MD
Conditions: NDG
Job posted: June 11th, 2018
Brigham and Women's HospitalBoston, MAPhD, MDNDGJun 11, 2018
Postdoctoral Fellow, Walker Lab

Postdoctoral Fellow, Walker Lab

(Click title to open job details in a new window.)
Description:

Adam Walker is seeking a postdoctoral fellow to join his laboratory at the University of Queensland in Brisbane, Australia. The lab focuses on molecular, cellular and mouse model studies of the causes and potential treatments for motor neuron disease (MND) and frontotemporal dementia. We are an enthusiastic, cooperative, dedicated and ambitious group working towards finding cures for disease. For more information please visit qbi.uq.edu.au/walkergroup and walkerneurolab.org.


This position will involve conducting and analysing experiments to understand molecular mechanisms and identify potential treatments for motor neuron disease and frontotemporal dementia, with a focus on cellular stress responses, protein aggregation and novel pathogenic biochemical pathways. You will use techniques including biochemistry, primary cell culture, immunohistochemistry, advanced molecular biology and microscopy, lentiviruses and AAVs, analysis of human tissues, and transgenic mouse stereotactic surgery, behavioural analysis and pre-clinical testing, to identify and understand new potential therapeutic targets.


Applicants must have a PhD in a relevant area of research, such as neuroscience or cell biology. You will have demonstrated expertise in techniques involving biochemistry, molecular biology, cell biology or mouse models of neurological disease (including stereotactic surgery in neonatal and adult mice).


Experience in the use of cutting-edge techniques including CRISPR and in vivo AAVs, and a deep understanding of molecular mechanisms of neurodegeneration with particular focus on MND and FTD will be an advantage. You will have a strong desire to make important scientific discoveries, to build new research directions and to apply your expertise and develop new skills to advance our research goals. Your record of high-profile first-author publications in neuroscience or cell biology together with your record of success in competitive funding schemes, and prizes and awards for research, will make you an ideal candidate for this position.


To discuss this role please contact Dr Adam Walker via email [email protected]


To submit an application for this role, use the Apply button on this webpage. All applicants must supply the following documents: Cover letter, Resume and Selection Criteria responses.


Note: The closing date has been extended to July 9, 2018.


Link: https://www.seek.com.au/job/36441307
Employer: University of Queensland
Location: Brisbane, Australia
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: June 11th, 2018
University of QueenslandBrisbane, AustraliaPhDALS, FTDJun 11, 2018
Postdoctoral Fellow, Xu Lab

Postdoctoral Fellow, Xu Lab

(Click title to open job details in a new window.)
Description:



A postdoctoral position is available in Zuoshang Xu’s laboratory to study mechanism of motoneuron degeneration in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. We are studying how mutant genes such as SOD1, PFN1 and TDP-43 cause motor neuron degeneration and ALS. Techniques utilized include transgenic mice, cell culture, fluorescent imaging, and other molecular, cellular and biochemical approaches.


Highly motivated scientists with a Ph.D., proficiency in molecular biology and a strong interest in neurodegenerative disease are encouraged to apply. Send curriculum vitae and names of three references to:


Zuoshang Xu, MD, Ph.D.


Department of Biochemistry and Molecular Pharmacology


University of Massachusetts Medical School


55 Lake Avenue N


Worcester, MA 01655


Fax: (508) 856-5080


e-mail: [email protected]





Link: https://careers-umms.icims.com/jobs/31164/post-doctoral-associate-/job
Employer: University of Massachusetts Medical School
Location: Worcester, MA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: June 11th, 2018
University of Massachusetts Medical SchoolWorcester, MAPhDALSJun 11, 2018
Postdoctoral Fellow, Butovsky Lab

Postdoctoral Fellow, Butovsky Lab

(Click title to open job details in a new window.)
Description:

Dr. Butovsky is seeking a highly-motivated post-doctoral fellow to join his team, whose major scientific interest is to understand the biology of resident microglia and peripheral innate immunity in homeostasis and neurodegenerative conditions. Dr. Butovsky and his lab are internationally recognized for investigations that have led to the identification of novel potential therapy targets for ALS and new roles of APOE in microglia regulation in neurodegenerative diseases including Alzheimer’s disease (Immunity and Nature, 2017). The lab is actively involved in multiple international and national collaborative efforts including those local to Brigham and Women’s Hospital, Harvard, and the Broad Institute of MIT and with clinical scientists to translate basic observations and validate their application in human disease. The laboratory is funded by multiple NIH grants and several awards from foundations such as the Cure Alzheimer’s Fund and the Amyotrophic Lateral Sclerosis Association; research support sustains studies related to identification of therapeutic targets and biomarkers of central and peripheral innate immunity. The ultimate goal of the laboratory is to find microglia- and monocyte-based immunomodulatory approaches to treat neurodegenerative diseases.


To apply, please email your CV, cover letter, three letters of reference, and contact information to [email protected] and copy [email protected] (Zoë Dale, administrative assistant).


Link: https://www.nature.com/naturejobs/science/jobs/646007-the-butovsky-laboratory-oleg-butovsky-ph-d-pi-assistant-professor-of-neurology-ann-romney-center-for-neurologic-diseases-brigham-and-women-s-hospital-harvard-medical-school
Employer: Brigham and Women's Hospital
Location: Boston, MA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: June 7th, 2018
Applications close: August 6th, 2018
Brigham and Women's HospitalBoston, MAPhDALSJun 07, 2018
Associate or Full Professor, Molecular Imaging

Associate or Full Professor, Molecular Imaging

(Click title to open job details in a new window.)
Description:

The Molecular Imaging Innovations Institute (MI3) in the Department of Radiology at Weill Cornell Medicine is seeking highly motivated applicants to join our institute, which is located in the brand new, state-of-the-art, Belfer Research Building. MI3is committed to becoming an internationally recognized institute of excellence in the discovery and development of new molecular imaging agents, and strategies for use in basic and translational research and clinical care. Scientists will have access to on-site imaging systems for preclinical and human studies including: MRI, PET/CT, PET/MR, SPECT, CT, optical and ultrasound.


Senior positions at the Associate or full Professorship levels will be considered commensurate with experience and track record of extramural funding and publications.


Qualified applicants should respond via email by submitting a letter of interest, including: research interests, current CV, and three references to:


Dr. Ching Tung

Director of Molecular Imaging Innovations Institute

Department of Radiology, Weill Cornell Medicine

[email protected]


Link: https://jobs.sciencecareers.org/job/482200/senior-faculty-positions-in-radiology-/?LinkSource=PremiumListing
Employer: Weill Cornell Medical College
Location: New York, NY
Sector: Academia
Degree required:
Conditions: NDG
Job posted: June 5th, 2018
Weill Cornell Medical CollegeNew York, NYNDGJun 05, 2018
Postdoctoral Fellow, Lloyd Lab

Postdoctoral Fellow, Lloyd Lab

(Click title to open job details in a new window.)
Description:

Postdoctoral positions are available at Johns Hopkins University School of Medicine to study cellular mechanisms underlying degenerative diseases of the neuromuscular system such as Inclusion Body Myositis (IBM) and Amyotrophic Lateral Sclerosis (ALS) in the laboratory of Thomas E. Lloyd, MD PhD. We are actively recruiting for a postdoctoral fellow to work on a mouse model of myosits in which human muscle biopsies are xenografted into immunodeficient mice. This exciting precision medicine initiatve will explore the interaction between the immune system and regenerating muscle in autoimmune and degenerative muscle and motor neuron diseases. Expertise in immunology, muscle, or mouse models of neuromuscular disease is preferred. The Lloyd laboratory uses a combination of genetic, molecular, cellular, physiologic, and imaging approaches in Drosophila, mouse, and iPS models in addition to human brain and muscle tissue to study the cell biology of degenerative diseases affecting the neuromuscular system.


Recent relevant publications include: Zhang K et al (2018) Cell 173:958; Lloyd TE et al (2017) Neurology 88:1454; Bharadwaj et al (2016) Hum Mol Gen 25:681; Zhang K et al (2015) Nature 525:56. Highly motivated and energetic candidates with a strong publication record are encouraged to apply. Interested applicants should send curriculum vitae to [email protected].


Link: https://www.nature.com/naturejobs/science/jobs/645751-postdoctoral-research-scientist
Employer: Johns Hopkins University
Location: Baltimore, MD
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: June 5th, 2018
Johns Hopkins UniversityBaltimore, MDPhDALSJun 05, 2018
Postdoctoral Fellow, Yang Lab

Postdoctoral Fellow, Yang Lab

(Click title to open job details in a new window.)
Description:

The Yang lab also studies pathogenic roles of astrocyte dysfunction in neurological diseases/disorders, such as fragile x syndrome (FXS) and amyotrophic lateral sclerosis (ALS). The lab employs novel genetically modified mouse tools, in combination with primary astrocyte and neuronal cultures, imaging, electrophysiological and biochemical/molecular techniques. The candidate must be able to handle rodents and are familiar with biochemical techniques and prior knowledge of neurodegenerative diseases is desirable. It is expected that the candidate should have a recent PhD (less than 2 years) in Neuroscience/Genetics/Cell Biology/Biochemistry or equivalent and is able to communicate well with others. To apply, please send your CV (via e-mail) including all past education and training, a brief description of research interests, list of publications and other scientific activities as well as names and e-mail addresses of three references to Dr. Yongjie Yang at: [email protected].


Link: https://neurojobs.sfn.org/jobs/11127600/postdoctoral-fellow-in-neuroscience-neuron-to-glia-signaling
Employer: Tufts University School of Medicine
Location: Boston, MA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: June 5th, 2018
Tufts University School of MedicineBoston, MAPhDALSJun 05, 2018
Associate Professor, Neuroscience

Associate Professor, Neuroscience

(Click title to open job details in a new window.)
Description:

The Eccles Institute of Neuroscience at The John Curtin School of Medical Research is seeking applications from highly motivated, internationally recognized neuroscientists to drive high-impact independent research programs as well as contribute to undergraduate and postgraduate teaching. These tenure-track positions will provide funding for 7 years in the first instance. Applicants will be expected to have an international research profile in neuroscience, teaching experience, and a competitive funding record. We are interested in expanding our expertise in molecular, cellular, systems and computational neuroscience, but are open to applications from exceptional neuroscientists in any area.


The Eccles Institute of Neuroscience (EIN), led by Professor Gregory Stuart, was launched in 2012 in new state-of-the-art facilities within the John Curtin School of Medical Research (JCSMR). EIN was planned and built specifically to allow co-location of much of the neuroscience research at the ANU under one roof. It currently comprises over a dozen independent research groups working in areas such as synaptic transmission, sensory processing, the retina and excitation-contraction coupling, with expertise in electrophysiology (patch-clamp & lipid bilayer), immunohistochemistry, advanced optical techniques (optogenetics & 2-photon), modeling and molecular biology. This research is being carried out in vitro, in vivo and in awake behaving animals. EIN provides staff and students with an exceptional environment for research on brain function, with a cellular focus and an emphasis on signal processing in sensory systems. For further informaiton on The John Curtin School of Medical Research or the Eccles Institute of Neuroscience please visit: http://jcsmr.anu.edu.au/


This position will be a tenure track appointment to engage a world-class academic for an initial period of seven years, with the option of renewal or conversion at the end of the initial employment agreement.


Job no: 525084

Salary package: $115,729-$128,825 per annum (Level C) / $138,643-$147,376 per annum (Level D) per annum plus 17% superannuation.


For further information, please contact Professor Greg Stuart, on +61 2 6125 8927, or [email protected]


Position description:  Level C_D_Fellow_Associate Professor_Neuroscience.pdf


 



Link: http://jobs.anu.edu.au/cw/en/job/525084/fellow-associate-professor-in-neuroscience-up-to-two-positions
Employer: Australian National University
Location: Canberra, Australia
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 4th, 2018
Applications close: July 2nd, 2018
Australian National UniversityCanberra, AustraliaPhDNDGJun 04, 2018
Professor or Associate Professor, Neuroscience

Professor or Associate Professor, Neuroscience

(Click title to open job details in a new window.)
Description:

Applications are invited for an Associate Professor or Professor of Neuroscience to join the School of Life Sciences (SLS). We particularly encourage applications from candidates who complement existing strengths in the School who perform research on the effects of ageing on brain function in mammalian models, including both healthy ageing and/or neurodegenerative processes. Those who can teach across a wide area of contemporary neuroscience and physiology and who can demonstrate, or have potential to attract, industrial support for their research may be given preference.


You will hold a PhD or equivalent and postdoctoral experience, with considerable evidence of sustained academic excellence and of success in raising research funding. Successful applicants will have an outstanding research track record, established lines of funded research, and the potential to continue to attract funding to develop your research portfolio. You will be able to show commitment to undergraduate and postgraduate education and preference may be given to candidates who hold teaching accreditation. Candidates should expect to demonstrate how they would strengthen partnerships and disciplines within the School, and how they would foster dynamic research collaborations within the university, on the international stage and with industry.


Salary: Associate Professor of Neuroscience – £ 49,149-£56,950 per annum or

Professor of Neurobiology – Competitive Salary


To be considered for this position, please complete the online application, including a CV, names of three expert referees who are able to comment on your readiness to embark on an independent career and a one-page cover letter. Please state clearly in your application form which level post you wish to be considered for.


For informal enquiries, in the first instance please contact: Professor Nicholas Dale ([email protected])


Employer: University of Warwick
Location: Warwick, England
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 1st, 2018
Applications close: June 27th, 2018
University of WarwickWarwick, EnglandPhDNDGJun 01, 2018
Professor, Computational Neuroscience

Professor, Computational Neuroscience

(Click title to open job details in a new window.)
Description:

The Département de neurosciences at the Université de Montréal invites applications for a faculty position at the assistant or associate level, in Systems/Computational Neuroscience. We are seeking candidates who use experimental and/or computational approaches to study how large-scale distributed brain networks implement behavioural-level phenomena such as sensorimotor control and decision-making, with a particular emphasis on system-level learning mechanisms. Ideal candidates will either combine multi-electrode, multi-area neurophysiological studies in behaving animals (in particular non-human primates) with sophisticated computational modeling of brain function, or alternatively, will use predominantly computational approaches to study how biologically realistic large-scale and recurrent network models simulate behavioral-level phenomena. The Département de neurosciences offers state of the art laboratory space and animal facilities for rodent and non-human primates research.


Link: https://jobs.sciencecareers.org/job/482110/professor-in-systems-computational-neuroscience-/
Employer: Université de Montréal
Location: Montréal, Canada
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: June 1st, 2018
Université de MontréalMontréal, CanadaPhDNDGJun 01, 2018
Assistant Professor, Neurological Disorders

Assistant Professor, Neurological Disorders

(Click title to open job details in a new window.)
Description:

To fulfill its mission, QBRI is recruiting independent, full-time Scientists (equivalent to Assistant Professor), Senior Scientists (equivalent to Associate Professor), and Principal Investigators (equivalent to Full Professor) for the Neurological Disorders Research Center, to lead and support basic, clinical and translational research on the genetics of neurodevelopmental and neurodegenerative diseases. Individuals with expertise in drug/biomarkers discovery, functional genomics, computational and systems biology, development of cellular and animal disease models, and neurodevelopment phenotyping are encouraged to apply.


Link: https://hbku.edu.qa/qbri/neurological-disorders-scientists
Employer: Qatar Biomedical Research Institute
Location: Doha, Qatar
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 29th, 2018
Qatar Biomedical Research InstituteDoha, QatarPhDNDGMay 29, 2018
Professor (Open Rank), Neuroscience

Professor (Open Rank), Neuroscience

(Click title to open job details in a new window.)
Description:

The Department of Cell Biology and Physiology and the Neuroscience Center at the University of North Carolina at Chapel Hill invite applications for an open-rank, tenure-track/tenure eligible faculty position. Research areas of particular interest include Alzheimer’s disease, neurodegeneration, pain, glial biology and glial diseases, but outstanding work in any area of neuroscience will be considered.


Applicants should apply online at http://unc.peopleadmin.com/postings/127292 . The online application will require a cover letter, curriculum vitae, brief (~1,500 word) statement of ongoing and planned research, and the names and contact information for four referees. Review of applications will begin November 1,2017, but applications will continue to be considered until the position is filled.


Link: https://unc.peopleadmin.com/postings/127292
Employer: University of North Carolina
Location: Chapel Hill, NC
Sector: Academia
Degree required: PhD, MD or MD/PhD
Conditions: NDG
Job posted: May 27th, 2018
University of North CarolinaChapel Hill, NCPhD, MD or MD/PhDNDGMay 27, 2018
Assistant or Associate Professor of Neurology

Assistant or Associate Professor of Neurology

(Click title to open job details in a new window.)
Description:

The Department of Neurology of Columbia University invites applications for a tenure-track faculty position at the rank of Assistant or Associate Professor. We seek a neurologist with specialty training in neuromuscular medicine, with particular expertise in the care of patients with amyotrophic lateral sclerosis (ALS). The successful candidate will have a primary affiliation with the Eleanor and Lou Gehrig ALS Center in the Neuromuscular Medicine Division, and will focus on the care of patients with ALS and other neuromuscular disorders, including those seen in the ALS and neuromuscular clinics. In addition to supporting the clinical activities of the ALS Center, the position will expand its basic, translational and/or clinical research program. Candidates with research interests in the genetics and basic biology of motor neuron disease, the development of novel ALS therapeutics, biomarker development or brain imaging are especially encouraged to apply. As a member of the Motor Neuron Center at Columbia, the new clinician-investigator will have the opportunity to interact and collaborate with a diverse group of individuals in basic science and clinical departments within the University. The ideal candidate will have extramural funding for research.


Link: https://academicjobs.columbia.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1527111978983
Employer: Columbia University
Location: New York, NY
Sector: Academia
Degree required: MD or MD/PhD
Conditions: ALS
Job posted: May 23rd, 2018
Columbia UniversityNew York, NYMD or MD/PhDALSMay 23, 2018
Director, Therapeutic Development

Director, Therapeutic Development

(Click title to open job details in a new window.)
Description:

We are currently seeking a new Medical Science Liason (Director of Therapeutic Development) to oversee the Program of Excellence focused on Lysosomal Storage, Neurodegenerative, Liver Metabolics, or Infantile Epilepsy diseases/disorders.

Reporting to the Executive Director of the Orphan Disease Center (ODC) and supporting a Program of Excellence, your goal will be to provide international leadership in establishing research agenda in rare diseases that are a high priority of the ODC. You will be developing strong partnerships with key stakeholders, including patient advocacy groups, partnering academic institutions and key opinion leaders in relevant diseases by organizing international scientific symposiums related to diseases of interest to the program of excellence, partnering with ODC staff to organize these events. You will have the primary responsibility for creating and executing a strategic plan, to establish clinical development for novel therapeutics. You will seek advisement from all relevant stakeholders, including patient advocacy groups, ODC leadership, and external advisors in the initial development of this plan. In executing this plan, you will undoubtedly be required to have extensive interactions with biopharmaceutical industry partners, knowledgeable on the development of novel therapeutics and will require you to travel to biomedical conferences. You will establish working groups within each disease to address research and clinical practice gaps, and focus on filling those gaps to further the development of effective treatments.


Link: https://www.linkedin.com/jobs/view/603668361/
Employer: University of Pennsylvania School of Medicine
Location: Philadelphia, PA
Sector: Academia
Degree required: PhD, MD preferred.
Conditions: NDG
Job posted: May 22nd, 2018
University of Pennsylvania School of MedicinePhiladelphia, PAPhD, MD preferred.NDGMay 22, 2018
Associate or Full Professor (Animal Disease Models)

Associate or Full Professor (Animal Disease Models)

(Click title to open job details in a new window.)
Description:

The Model Animal Research Center (MARC) of Nanjing University, which focuses on basic and translational medicine research with the achievement published in high profile journals such as Cell, Nature, Neuron, Nature Medicine and their sister series, invites applications for full-time faculty positions, at academic ranks of Associate or Full Professor. Individuals with demonstrated accomplishments in, but not limited to, the following areas are encouraged to apply – 1) Organogenesis and Birth Defect 2) Physiological Homeostasis Control and Metabolic Disease 3) Cancer and Stem Cell Biology 4) Neurobiology and neurodegenerative disease 5) Bioinformatics Specialists. Highly competitive research package will be provided in a stimulating and nurturing research environment: substantial start-up funds from “National Youth 1000-Talent Plan” and Nanjing University “Deng Feng Plan”; excellent laboratory space; and outstanding Vivarium Facility. For more information and to apply visit website: http://www.nicemice.cn


Link: https://jobs.sciencecareers.org/job/481516/full-time-professor-pi-positions-in-model-animal-research-center-marc-of-nanjing-university/
Employer: Nanjing University
Location: Nanjing, China
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 21st, 2018
Nanjing UniversityNanjing, ChinaPhDNDGMay 21, 2018
Assistant Professor, Cell and Molecular Biology

Assistant Professor, Cell and Molecular Biology

(Click title to open job details in a new window.)
Description:

The George and Anne Ryan Institute for Neuroscience and the Department of Cell and Molecular Biology invite applications for the position of Assistant Professor.


The successful candidate will have an appointment in the Department of Cell and Molecular Biology (CMB) in the College of the Environment and Life Sciences. The candidate will be expected to establish a basic science or translational research program in an area that complements the mission of the Ryan Institute and the Department of Cell and Molecular Biology, and is supported by extramural funding. The successful candidate will also contribute to the University’s teaching mission and participate in service activities.


The Ryan Institute is an interdisciplinary research institute that is focused on discovering and developing disease-modifying therapies for neurodegenerative diseases. CMB is a research and teaching department focused on the cellular and molecular basis of physiology and disease. We are building a faculty with a strong record of successful laboratory and/or clinical research that support our mission of integrating discovery science, translational medicine, education and community engagement to identify and deliver tomorrow’s treatments today.


Responsible for managing and maintaining the COP Heber Youngken Medicinal Garden including plants in Avedisian Hall, COP assigned greenhouse(s), and surrounding COP courtyard environs. Lead students, faculty, and garden volunteers to enable use of Medicinal Garden for research, teaching, public education and outreach.


Visit the URI jobs website at: https://jobs.uri.edu  to apply and view complete details for job posting (F00087).  Please attach the following 3 (PDF) documents to your online Faculty Employment Application:  (#1) Cover letter including a description of how your qualifications match the requirements for the position, (#2) Curriculum Vitae, which should include the names and contact information for three professional references, and (#3) “Other Document” a research statement or sample(s) of relevant scholarly work (as one complete document).


Application Deadline:  This is an open until filled search. First consideration will be given to applications received by June 17, 2018.


Link: https://neurojobs.sfn.org/jobs/11056889/asst-professor-the-george-and-anne-ryan-institute-for-neuroscience-and-cell-and-molecular-biol
Employer: University of Rhode Island
Location: Kingston, RI
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 16th, 2018
University of Rhode IslandKingston, RIPhDNDGMay 16, 2018
Bioinformatics Specialist

Bioinformatics Specialist

(Click title to open job details in a new window.)
Description:

The VIB-KU Leuven Center for Brain & Disease Research is seeking a highly motivated Single Cell Bioinformatics Specialist. You will collaborate with the 17 research groups within the Center and provide essential input on computational biology aspects of their research projects. In this job you will be confronted with exciting research questions in neurobiology and neurodegeneration; and with a broad spectrum of computational challenges and single-cell omics data sets. You will work closely with in the Laboratory of Computational Biology (Stein Aerts Lab) and with the single cell expertise unit (Suresh Poovathingal) and you will be part of an active bioinformatics community in Leuven, allowing daily interactions with colleague bioinformaticians.


For additional information concerning this job please contact Prof. Stein Aerts.


To apply,  submit your application to our website. Please include in your application your CV (including a list of your scientific publications, and the names and contact information of 3 references) as well as a cover letter describing your motivation, previous research experience and background. Please provide also a track record of previous coding work, e.g. include your github web address.


Link: https://vibvzw.jobsoid.com/j/11971/single-cell-bioinformatics-specialist
Employer: VIB
Location: Leuven, Belgium
Sector: Academia
Degree required: MSc or PhD
Conditions: NDG
Job posted: May 16th, 2018
VIBLeuven, BelgiumMSc or PhDNDGMay 16, 2018
Principal Scientist

Principal Scientist

(Click title to open job details in a new window.)
Description:

Purpose:


This person will work closely with members of the R&D organization, CROs, consultants, corporate collaborators as well as the senior leadership team to ensure development and execution of drug discovery projects according to company goals. This person will report to the SVP of Translational Sciences.


Essential Job Responsibilities:



  • Lead drug discovery programs using both internal and external (CRO, academia) resources

  • Mentor junior scientists in project leadership in a matrix environment

  • Provide scientific and strategic input into the company’s target pipeline and best disease indication selection


Quantitative Dimensions:



  • Lead all aspects of drug discovery project(s) using internal and external resources

  • Proactively identify critical-path project goals, activities, and constraints, propose mitigation plans when necessary

  • Direct, motivate and hold accountable to goals and timelines all internal and external team members associated with the project

  • Effectively communicate project status, changes to plan and risks to senior leadership team

  • Contribute in identifying the most relevant external resources for the project

  • Contribute to strategies that advance projects from early stage to IND and clinical development

  • Contribute to the company’s scientific strategy


Qualifications:


Required



  • PhD degree in pharmacology, biology, molecular biology, biochemistry, or related field

  • At least 8 years of experience in a drug discovery setting (biotech or large pharma)

  • Prior experience in leading drug discovery projects from lead discovery to IND

  • Exceptional demonstration of scientific leadership and strategy, track record of leading value-creating accomplishments, external recognition of scientific leadership in translational setting

  • Excellent written and oral communication skills

  • Ability to work productively in a collaborative and cross functional team environment within and outside of Mitobridge


Preferred



  • Experience in areas such as muscle, kidney, metabolic, neurodegenerative diseases, rare diseases and/or mitochondrial biology

  • A great sense of urgency and ownership for moving projects efficiently forward

  • Experience with due diligence of business development opportunities in early and late stage programs


Link: https://astellascareers.jobs/cambridge-ma/principle-scientist-research-fellow/8FE07F4785A848658683CC64D5A32259/job/?
Employer: Astellas Pharma
Location: Cambridge, MA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 16th, 2018
Astellas PharmaCambridge, MAPhDNDGMay 16, 2018
Research Specialist

Research Specialist

(Click title to open job details in a new window.)
Description:

A Lead Research Specialist position is available in the Center for Neurodegenerative Disease to join a dynamic research environment that uses a wide range of techniques and technologies to study neurodegenerative disease (e.g., Alzheimer’s disease, amyotrophic lateral sclerosis) pathogenesis. The successful applicant will be self-motivated and capable of working both independently and as a member of a team. Responsibilities will include assisting with the procurement and banking of human autopsy brain specimens and with distribution of tissue and biospecimens to investigators. He/she will also share responsibility for histological and immunohistochemical staining of human and rodent tissues. The successful applicant will be familiar with and train users in the proper use of shared laboratory equipment, and will share responsibility for maintaining the laboratory, including monitoring the storage and disposal of hazardous substances, ordering supplies, calibrating and performing routine repair and maintenance of equipment, interfacing with service personnel for equipment repairs, and maintaining and documenting laboratory safety standards. Upon hiring, the employee must complete the Laboratory Safety Training class and undergo immunization against potentially hazardous agents, as required by Emory University policy. Basic computer experience (Microsoft Word, Excel, etc.) and strong organizational and record-keeping skills are essential. Experience with Western blotting, confocal microscopy, tissue sectioning, histology and/or immunohistochemistry is highly desirable.


Link: https://staff-emory.icims.com/jobs/20322/research-specialist%2c-lead/job?hub=13&mobile=false&width=1150&height=500&bga=true&needsRedirect=false&jan1offset=-300&jun1offset=-240
Employer: Emory University
Location: Atlanta, GA
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: May 15th, 2018
Emory UniversityAtlanta, GABSALSMay 15, 2018
Postdoctoral Fellow, Zhang Lab

Postdoctoral Fellow, Zhang Lab

(Click title to open job details in a new window.)
Description:

Postdoctoral positions are available at the University of Wisconsin-Madison to study neural stem/progenitor cell self-renewal /reprogramming and functional dissection / therapeutic implication of human neural cells in neurological disorders. PhD or equivalent in cell / molecular / developmental biology, neuroscience, or chemistry is required. Experiences in electrophysiology, small animal microsurgery, genome editing, or 3D printing are highly desirable. Compensation follows the NIH standard. The Zhang laboratory is a leading group studying neural specification of human pluripotent stem cells and application of stem cells in developing therapeutics for neurological diseases (e.g., Cell Stem Cell, 2014, 2015, 2016, Nature Biotechnology, 2016, Nature Medicine, 2016, Nature Communication, 2017, Stem Cell Reports 2017/18). It is located in the NIH-sponsored Waisman Center that is dedicated for studying human development, developmental disability, and neurodegenerative diseases. Candidates enthusiastic in pursuing regenerative sciences are welcome to join this vibrant group in the beautiful city of Madison.


Link: https://www.nature.com/naturejobs/science/jobs/644297-postdoctoral-positions-in-stem-cells-and-neural-regeneration
Employer: University of Wisconsin
Location: Madison, WI
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: May 14th, 2018
University of WisconsinMadison, WIPhDALSMay 14, 2018
Bioinformatics Specialist

Bioinformatics Specialist

(Click title to open job details in a new window.)
Description:

A Bioinformatics Staff Scientist position is available at the DZNE in Tübingen within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink. The research focus of our group is to identify genetic risk factors for neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Frontal-Temporal Dementia/Motor Neuron Disease, Progressive Supranuclear Palsy and Ataxia in close collaboration with our clinical partners. As partners in the International Parkinson’s Disease Genomics Consortium (IPDGC) (http://pdgenetics.org/), we participate in large scale genetic and genomic studies to identify new genetic risk factors and to characterize the biological consequences of these mutations and risk factors by using automated high-throughput cellular screens combined with genomic and transcriptomic approaches. For further details on the scientific program of the group, please refer to http://www.dzne.de/en/sites/tuebingen/research-groups/heutink.html.


To apply, submit your application online: https://jobs.dzne.de/en/jobs/184/form .


Link: https://www.nature.com/naturejobs/science/jobs/644277-bioinformatics-staff-scientist-f-m
Employer: German Center for Neurodegenerative Diseases (DZNE)
Location: Tübingen, Germany
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: May 13th, 2018
German Center for Neurodegenerative Diseases (DZNE)Tübingen, GermanyPhDALS, FTDMay 13, 2018
Graduate Studentship, Locker Lab

Graduate Studentship, Locker Lab

(Click title to open job details in a new window.)
Description:

Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS) areneurodegenerative disorders (NDs) with proteostasis defects. They represent an ideal set of diseases covering >70% of patients to increase our understanding of the molecular basis of NDs. The associated pathologies are difficult to truly model and compare using animals because (i) they are mainly caused by sporadic forms of the diseases, and (ii) models do not recapitulate the basic cellular changes observed in patients. Our aim is to achieve a global understanding of RNA translation and stress granules regulation across these neurodegenerative diseases using novel genetically engineered isogenic human stem cell lines. This will identify key regulatory nodes, across diseases, revealing new points for therapeutic interventions.The PhD candidate will work as part of an EU/MRC-funded trans-national consortium that has developed control fibroblasts genetically engineered into disease cell lines (project grant MR/R02426X/1), allowing studies within identical genetic backgrounds. Following training with our project partners at McGill (Canada) and QMUL (UK), the control and disease-model iPSCs will be used to differentiate neuronal cell populations including forebrain cortical-like neurons, midbrain dopamine-like and glial astrocyte-like cells. Subsequently, the candidate will be trained in confocal microscopy techniques to detect and quantity stress granules in cells, measure translational activity globally and specifically at the mRNA level using ribosomes profiling.


Applicants are expected to hold a good honours degree (upper second) in an appropriate discipline, but prior experience in research or industry may be acceptable. Enthusiasm for, and commitment to, independent study is essential.


The appointed candidate will supported by a Medical Research Council grant (MR/R02426X/1: £310.088,70) awarded to N.Locker , for 3 years of PhD studies within which the candidate is expected to submit their PhD thesis. The studentship rates and minimum doctoral stipend will align to UKRI guidelines as follows: stipend for 2017/18 is £14,553; fee 2017/18 is £4,195. This will also cover bench fees associated with the projects, small equipment, travels for training purpose and conference attendance.


For further details and an informal discussion please contact Dr Nicolas Locker at [email protected] prior to submitting an application. Formal applications should be submitted through our Biosciences and Medicine programme page. You should make clear in your application that you are applying for this studentship. You should also submit a cover letter stating that you are a UK/EU national and willing to go through the required security vetting process.


Link: https://jobs.surrey.ac.uk/vacancy.aspx?ref=035218
Employer: University of Surrey
Location: Guildford, England
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: May 11th, 2018
University of SurreyGuildford, EnglandBSALSMay 11, 2018
Group Leader, Neurobiology

Group Leader, Neurobiology

(Click title to open job details in a new window.)
Description:

The Neurobiology Division of the Medical Research Councils Laboratory of Molecular Biology (MRC LMB) invites applications for a Programme Leader-Track position.   We seek a scientist with a focus on the elucidation of fundamental molecular mechanisms that determine the structure and function of the neuronal synapse, in health and disease.  An emphasis on the development and application of molecular neurobiological approaches is essential, and the application of cutting-edge light and/or electron microscopic imaging is encouraged.  The primary selection criteria are scientific excellence and potential for synergy with our existing research programmes, both within the Division (encompassing neuronal molecular cell biology, neural circuits and simple behaviours, and the molecular/ cell biological basis of neurodegeneration) and across the wider LMB.  You should hold a PhD and have an excellent publication record, be internationally recognised for your work and have outstanding potential for independent research.


The position comes with substantial core funding sufficient to establish your research group, and applications for additional external grant support are encouraged.  The LMB has an exceptional record of ground-breaking research, and in 2013 moved into a new building with outstanding core facilities including those for light and electron microscopy and mass spectrometry, as well as electronic and instrumentation workshops.  Administrative duties are minimal and no teaching is required.  Interactions across the four Divisions of the LMB are encouraged.  The University of Cambridge and affiliated institutions form a vibrant Neuroscience community (http://www.neuroscience.cam.ac.uk/).


The appointment will be made at Programme Leader-Track level, and candidates should have a strong international track record of relevant independent research and an ability to lead a research team, pursuing original approaches to long-term research goals.


Find out more about the LMB’s Neurobiology Division at http://www2.mrc-lmb.cam.ac.uk/research/neurobiology/.  Informal enquiries can be addressed to Head of Division, Michael Hastings ([email protected]).  For further information about the MRC visit www.mrc.ac.uk


To apply, submit your application online.  Applications should include a covering letter and full CV, an outline of current research interests (1 page) and a proposal for future research (up to 2 pages), along with the names and addresses of three professional referees who have agreed to be contacted prior to interview.


Link: https://mrc.tal.net/vx/mobile-0/appcentre-ext/brand-3/candidate/so/pm/4/pl/1/opp/834-Programme-Leader-Track-Neurobiology-Dr-Michael-Hastings-LMB-834/en-GB
Employer: UKRI MRC Laboratory of Molecular Biology
Location: Cambridge, England
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 10th, 2018
UKRI MRC Laboratory of Molecular BiologyCambridge, EnglandPhDNDGMay 10, 2018
Research Technologist, Morrison and Rothstein Labs

Research Technologist, Morrison and Rothstein Labs

(Click title to open job details in a new window.)
Description:

A Research Technologist to work in the laboratories of Drs. Brett Morrison and Jeffrey Rothstein in the Department of Neurology. Our laboratories study the pathogenesis of the devastating motor neuron disease, amyotrophic lateral sclerosis (ALS; commonly referred to as Lou Gehrig’s disease). A particular focus is on the role played by oligodendrocytes, a key support cell in the brain that is dysfunctional and degenerates in ALS.


Specific duties & responsibilities:


The responsibilities of the individual in this position will be to independently pursue new projects as well as work collaboratively with the other members of the lab (principal investigators, post-docs, graduate students, and research technicians) on ongoing projects. In addition to performing laboratory experiments, ongoing responsibilities will include the management of a transgenic mouse colony, assisting the laboratory manager with the ordering of laboratory supplies, and attending all required laboratory meetings.


Link: https://jobs.jhu.edu/job/Baltimore-Research-Technologist-MD-21205/437413200/
Employer: Johs Hopkins University
Location: Baltimore, MD
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: May 10th, 2018
Johs Hopkins UniversityBaltimore, MDBA or BSALSMay 10, 2018
Neurologist

Neurologist

(Click title to open job details in a new window.)
Description:

The Peripheral Nervous System, Muscle and ALS Department, Pasteur 2 new Hospital, CHU de Nice (France) is actually seeking a Neurologist with immediate availability for a Clinical and Research position. This department is certified as Neuromuscular Diseases Reference Center and ALS Reference Center. These Centers are affiliated to French rare diseases Healthcare Network (FILNEMUS) and French rare diseases Healthcare Network: Amyotrophic lateral sclerosis and rare motor neuron diseases (FILSLAN). The Department has also been labeled as being part of the European Reference Networks-NeuroMuscular Diseases (ERN-NMD) as Center of Excellence.


With an active file of more than 2000 patients, the department is particularly involved in diagnosis and multidisciplinary care of patients suffering from myopathies, myasthenia, peripheral neuropathies and ALS. This activity implies consultations, day and week hospitalizations sectors. It is composed of an electrophysiology platform and possesses the necessary means for the performance and the analysis of muscle or nerve biopsies. The Physicians from the Department are particularly involved in Clinical and Fundamental Research projects in connection with IRCAN from the University of Nice- Sophia Antipolis- Faculty of Medicine, INSERM U1081 – CNRS UMR 7284 and INRIA. We participate in industrial Therapeutic Trials.


The Department is part of the Pole of Clinical Neurosciences, Central Nervous System department and the Neurovascular Unit which are located in the same Hospital. It contributes to ensure the continuity and constant care of patients suffering from neurologic diseases.


The required skills for application are the following:


*Having a Medical Doctor Thesis and possessing a Diploma of specialty in Neurology which is recognized in France

*Being fluent in French (oral and written) and in English.

*Having an overall knowledge of neuromuscular pathologies especially in peripheral nerve ones and being able to ensure a diagnostic activity and electrophysiological diagnosis. (ENMG).

*Candidates having knowledge and or diploma justifying their expertise in Neuromuscular diseases field (clinical, electrophysiology) will be considered in priority.


Dynamism and willingness of being involved in Research projects will be highly appreciated qualities.


Interested candidates will beforehand contact Pr Sacconi- Head of Department. They will send their CV containing their Title and works, and a cover letter in French .


Pr Sabrina SACCONI


Système Nerveux Périphérique, Muscle et SLA

Hôpital Pasteur 2, Avenue voie Romaine,

06001 Nice cedex 01, France

email : [email protected],

Téléphone : +33 (0)492 03 5757


Link: https://en.academicpositions.fi/ad/chu-de-nice/2018/neurologist-with-immediate-availability-for-a-clinical-and-research-position/112120
Employer: Centre Hospitalier Universitaire de Nice
Location: Nice, France
Sector: Academia
Degree required: MD
Conditions: ALS
Job posted: May 5th, 2018
Centre Hospitalier Universitaire de NiceNice, FranceMDALSMay 05, 2018

Industry

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
NEW! Research Associate

Research Associate

(Click title to open job details in a new window.)
Description:

We are looking to recruit a talented and motivated Research Associate to join our highly dynamic neuroscience team. The successful candidate would work on the understanding of neurodegenerative diseases and the discovery of novel therapeutic targets and neuroprotection strategies. In addition to our commitment to multidisciplinary, cutting-edge research, we are committed to mentoring, supporting, and encouraging our team members to grow scientifically, take initiatives, bring new ideas, and play a leading role in our research, which is an important part of our culture and the secret to our success. Candidates who aspire to become part of an innovative and scientifically inspiring environment, with unlimited resources and state-of-the-art facilities and technologies, who enjoy collaborating within and outside of a team, have a passion for scientific discovery, face challenges with a positive attitude, can multitask and work independently, and are dedicated to high quality research, are encouraged to apply. The ideal candidate will be able to fulfill the following key responsibilities and will meet the following requirements:


Responsibilities:


1) Characterize the aggregation properties of proteins associated with neurodegeneration using biochemistry and immunocytochemistry.

2) Examine the role of protein misfolding and aggregation in neuronal function in vitro and in vivo.

3) Investigate mechanisms of cell-to-cell propagation of protein aggregation using cell-based systems.

4) Perform immunohistochemical, biochemical and behavioral analyses of mouse models of neurodegenerative diseases, such as amyotrophic lateral sclerosis, frontotemporal dementia and multiple sclerosis.

5) Generate DNA constructs and develop assays for examination of the relationship between protein homeostasis mechanisms and protein aggregation and clearance.

6) Keep abreast of current/relevant literature in order to further develop scientific expertise, new assays and expand scientific/technical knowledge and skill sets.

7) Participate in group and departmental meetings and give presentations.

8) Document experiments, results and findings in laboratory notebook.

9) Contribute to writing of protocols, method development reports, and articles for publication.


Link: https://careers.regeneron.com/job/REGEA0026306190/Research-Associate-neurodegenerative-diseases
Employer: Regeneron
Location: Tarrytown, NY
Sector: Industry
Degree required: BS degree (MS preferred)
Conditions: NDG
Job posted: July 18th, 2018
RegeneronTarrytown, NYBS degree (MS preferred)NDGJul 18, 2018
NEW! Research Scientist, Molecular and Cellular Immunology

Research Scientist, Molecular and Cellular Immunology

(Click title to open job details in a new window.)
Description:

Amgen Neuroscience is looking for a motivated cell and molecular biologist to be a driver of our efforts to develop therapies for neurodegenerative disease. As the field of neuroimmunology holds great potential for neurodegenerative disease treatments, the candidate will bring a perspective on the innate immune system to construct assays and uncover decision-driving human biology. This position is for the dedicated experimentalist who will work in a multidisciplinary team as part of our pre-clinical research. Core areas of focus will be translating genetics and human biology observations into both in vitro and in vivo systems to understand modifiers of neurodegenerative pathology. Also, this position will be charged with exploring the emerging target space of the immune system in the brain via functional genomics (siRNA, shRNA, CRISPR/Cas9, and chemogenomic screens), proteomics, and transcriptomics.


A second point of emphasis for this position is innovation in genome editing techniques (CRISPR/Cas9 and variants) to advance neurodegenerative disease research. To validate targets in the neuroimmunology space, we seek to integrating cell line generation, molecular biology, and genome editing methodologies. Working effectively with bio-informaticists, chemists, and a variety of in vivo and in vitro-oriented collaborators is essential for success. This position is designed for someone seeking to become a technical leader and a critical resource within Amgen Neuroscience. A core aim will be discovering new biological insight to enable drug discovery programs within Amgen and to impact the external scientific community through publication.


Link: https://careers.amgen.com/job/8507703/molecular-and-cellular-neuroimmunologist-cambridge-ma/
Employer: Amgen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: July 18th, 2018
AmgenCambridge, MAPhDNDGJul 18, 2018
Senior Leader, Translational Medicine, Neurology

Senior Leader, Translational Medicine, Neurology

(Click title to open job details in a new window.)
Description:

The Neuroscience Translational Medicine group at Roche is recruiting a Translational Medicine Leader to lead early development projects, chiefly in the areas of neurodegenerative and neuro-immunologic disorders. The position reports directly to the Section Head of Translational Medicine Neuroscience/Neurology. In this role you will lead early stage clinical projects through proof of mechanism and proof of concept to transform molecules into new medicines in area with high unmet medical need.


Link: https://www.roche.com/careers/jobs/jobsearch/job.htm?id=E-201805-105704&locale=en&title=Senior+Translational+Medicine+Leader-Neurology
Employer: Roche
Location: Basel, Switzerland
Sector: Industry
Degree required: MD or MD/PhD
Conditions: NDG
Job posted: July 6th, 2018
RocheBasel, SwitzerlandMD or MD/PhDNDGJul 06, 2018
Clinical Scientist

Clinical Scientist

(Click title to open job details in a new window.)
Description:

We are looking for an enthusiastic, self-motivated, hands-on scientist who is capable of performing multiple duties inherent in clinical development and comfortable working in an open environment. The clinical scientist will be an integral member of the clinical team and support programs both in the clinic and preparing to enter the clinic. This person will provide cross-functional support to programs by working closely the Medical, Operational, Regulatory, Biomarker, and Technical groups. Successful applicants are expected to function with a high degree of independence in a fast-paced start-up environment while also working collaboratively within a multidisciplinary team that is dedicated to the development of new therapies for neurodegenerative diseases.


Link: https://www.linkedin.com/jobs/view/clinical-scientist-at-prevail-therapeutics-706779217/
Employer: Prevail Therapeutics
Location: New York, NY
Sector: Industry
Degree required: PhD or PharmD
Conditions: NDG
Job posted: July 5th, 2018
Prevail TherapeuticsNew York, NYPhD or PharmDNDGJul 05, 2018
Medical Director, Clinical Development (ALS, SMA)

Medical Director, Clinical Development (ALS, SMA)

(Click title to open job details in a new window.)
Description:

The position of Associate Medical Director/Medical Director, Clinical Development sits within Pain, Neuromuscular and Rare Disease of Late Stage Clinical Development. The new Medical Director will support neuromuscular indications including Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS). The successful candidate will demonstrate the flexibility and capability to function at a high level across multiple studies. Activities include direct responsibility for advancing high priority clinical programs through clinical study design and execution, development of biomarker strategies, as well as interpretation of data from key clinical studies. The individual who assumes this position will interact with multiple levels of management within Biogen, external stakeholders in the medical community as well with global regulatory authorities.


Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=812014#jobDetails=812014_5140
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: MD, PhD, or PharmD
Conditions: ALS, SMA
Job posted: June 29th, 2018
BiogenCambridge, MAMD, PhD, or PharmDALS, SMAJun 29, 2018
Senior Scientist, Neuroscience

Senior Scientist, Neuroscience

(Click title to open job details in a new window.)
Description:

The Neuroscience Exploratory Biology Lead at Celgene will have the responsibility for testing novel concepts in cell based drug discovery and target validation for neurodegenerative diseases. The two foundational activities of this group will be to evaluate and implement new cell based screening approaches and, secondly, to develop and support internal collaborations that exploit Celgene expertise in target and lead discovery. The position will have an outward facing role as well, utilizing and leading collaborations with contract research organizations, academic labs, and other drug discovery companies to fulfill the mission of developing new therapeutics for neurodegenerative diseases. The candidate should have demonstrated expertise in applying a variety of genetic and compound based screening approaches in a relevant field of biology. The candidate should be equally adept contributing to our science directly and through leading and guiding others.


Link: http://jobs.celgene.com/ShowJob/Id/1680289/Sr.%20Scientist,%20Neuroscience%20%20%20Imaging
Employer: Celgene
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: June 24th, 2018
CelgeneCambridge, MAPhDNDGJun 24, 2018
Scientist I

Scientist I

(Click title to open job details in a new window.)
Description:

Voyager is seeking a highly motivated neurobiologist to contribute to our research team. This is an ideal position for an individual with a strong background in in vivo experimental methods and readouts, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. The individual will work in the laboratory and be responsible for experimental execution and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. The successful candidate will have extensive prior experience in drug discovery in neurodegenerative diseases and with hands-on techniques in stereotaxic surgery, in vivo behavioral assays of rodent models, CNS tissue dissection, and downstream analysis (RT-qPCR, western blot and ELISA).


Link: https://www.linkedin.com/jobs/view/726802274/
Employer: Voyager Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: June 16th, 2018
Voyager TherapeuticsCambridge, MAPhDNDGJun 16, 2018
Director, Research, Neuroscience (ALS and PD)

Director, Research, Neuroscience (ALS and PD)

(Click title to open job details in a new window.)
Description:

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring a Director, Research in our Neuroscience group at our Research and Development facility in Cambridge MA (AMA).


•Lead Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) discovery research efforts from target identification and validation to preclinical discovery characterization and clinical candidate nomination


•Develop and execute a research strategy to establish a sustainable and innovative pipeline in PD and ALS with a strong emphasis on human genetic insights


•Enhance the scientific reputation of Amgen and increase the external visibility in the PD and ALS areas by establishing impactful external research collaborations, participating in and presenting at key external meetings and publishing in peer-reviewed journals


•Build seamless collaborative partnership with Alzheimer’s disease therapeutic team, and other Neuroscience groups, to maximize resources and eliminate operational redundancies


•Ensure a highly effective partnership with functions in Therapeutic Discovery, Translational Sciences, Clinical Development, Process Development and Commercial and effectively position preclinical development candidates with these key stakeholders


•Participate in business development efforts resulting in the acquisition of innovative assets and/or enabling technologies that enhance the PD and ALS discovery research pipeline


•Recruit, develop and retain world class scientists, building a strong research team as evidenced by pipeline productivity and external scientific reputation


•Effectively represent Amgen by presenting the company’s capabilities and technologies and value of the PD, ALS and Neuroscience pipeline to external constituents


•Ensure that Amgen derives its sense of purpose from the needs of the patient and that all key decisions are made from a patient-centered perspective


Link: https://careers.amgen.com/job/8390459/dir-research-neuroscience-cambridge-ma/
Employer: Amgen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD preferred
Conditions: ALS
Job posted: June 12th, 2018
AmgenCambridge, MAPhD preferredALSJun 12, 2018
Research Scientist, Senior Research Scientist

Research Scientist, Senior Research Scientist

(Click title to open job details in a new window.)
Description:

Prevail Therapeutics is a venture capital-backed, New York City-based biotechnology company, with a mission to cure Parkinson’s disease and other neurodegenerative diseases using gene therapy approaches. The primary responsibility is to perform bioanalytical and cell-based assays and to assist our efforts to identify and advance the development of novel targets for neurodegenerative disorders. We are looking for an enthusiastic, self-motivated, hands-on, scientist with excellent interpersonal skills who is comfortable working in an open environment spanning multiple functions. As an early hire at a new company, you will have exposure to senior management, to all activities at Prevail, and you will be influential in championing and developing Prevail’s culture.


Link: https://jobs.sciencecareers.org/job/482363/multiple-positions-at-varying-levels-of-scientist/
Employer: Prevail Therapeutics
Location: New York, NY
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: June 12th, 2018
Prevail TherapeuticsNew York, NYPhDNDGJun 12, 2018
Director, Antibody Discovery

Director, Antibody Discovery

(Click title to open job details in a new window.)
Description:

Voyager is seeking a highly motivated scientist and leader with extensive experience in therapeutic antibody discovery and development to contribute to our research team and build the Antibody Platform at the company.


This individual will build and lead a platform effort on antibody discovery and engineering including but not limited to AAV-vectorized antibodies, integrating both internal and external resources. Incumbent will also play an important role in business development opportunities and ongoing and future partnerships. The candidate should have substantial working familiarity and demonstrated success with state-of-the-art approaches for generating, selecting, humanizing and optimizing human antibodies and antibody fragments against targets of interest. These approaches include tools and systems such as transgenic mouse strains that produce human antibodies, high throughput hybridoma and B-cell cloning from immunized animals and from human samples, and display technologies for affinity maturation. Responsibilities will include the development of a strategy and implementation of plans for rapid advancement of the vectorized antibody platform, and oversight of a group responsible for activities that include hybridoma screening, antibody gene cloning and sequencing, recombinant antibody expression, antibody humanization, lead antibody identification, antibody optimization including affinity maturation, and antibody characterization. This is an ideal position for an individual who is energetic and thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech company environment. This role is located in Cambridge, MA.


Link: https://www.linkedin.com/jobs/view/618406811/
Employer: Voyager Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: June 1st, 2018
Voyager TherapeuticsCambridge, MAPhDNDGJun 01, 2018
Research Associate

Research Associate

(Click title to open job details in a new window.)
Description:

BlueRock Therapeutics is a next-generation regenerative medicine company focused on breakthrough treatments and new horizons in medicine. BlueRock Therapeutics’ platform is based on state of the art pluripotent stem cell engineering tools and expansion technology. The company represents a strategic partnership between Bayer and Versant Ventures, and has been granted access to one of the largest-ever Series A financings in biotech.


As part of BlueRock Therapeutics vision to change the future of medicine by enabling ground-breaking cell therapies. The successful candidate will be a key technical contributor of a dynamic and progressive team developing novel therapeutics. This challenging opportunity requires in depth knowledge of neurodegenerative diseases as well as stem cell biology. The ideal candidate will be a highly motivated individual who leads from the bench and enjoys having broad responsibilities and opportunities. The ability to effectively communicate with internal team members is critical. Collaboration with a highly-motivated, world-class team of scientists and engineers promises an exciting and engaging work environment for motivated, self-starting candidates. Familiarity with cGMP aseptic manufacturing regulations is a plus.


Link: https://www.linkedin.com/jobs/view/712513567/
Employer: BlueRock Therapeutics
Location: New York, NY
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: May 31st, 2018
BlueRock TherapeuticsNew York, NYBS or MSNDGMay 31, 2018
Postdoctoral Fellow, ALS

Postdoctoral Fellow, ALS

(Click title to open job details in a new window.)
Description:

Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly qualified and motivated Postdoctoral Scientist to investigate the underlying disease biology of amyotrophic lateral sclerosis (ALS). The successful candidate will establish in vitro human glial and neuronal models to identify and validate innovative therapeutic targets for the treatment of ALS. The candidate will also evaluate the impact of engaging these novel targets in ALS transgenic mouse models.


Link: https://jobs.sanofi.us/job/framingham/postdoctoral-fellow-cns-genetic-disease-research-neuroscience-research-ta/507/8177065
Employer: Sanofi
Location: Framingham, MA
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: May 24th, 2018
SanofiFramingham, MAPhDALSMay 24, 2018

Non-Profit and Government

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
Epidemiologist

Epidemiologist

(Click title to open job details in a new window.)
Description:

The Epidemiologist I serves as the Registry Coordinator for the Massachusetts statewide registry of amyotrophic lateral sclerosis (ALS). Responsibilities include those related to the day-to-day operation of the Registry, including contact with all patient reporting sources to ensure complete case ascertainment, oversight of data abstraction and data verification activities, data entry of all clinical files received, and the oversight of all electronic and paper Registry files.


This position is also responsible for maintaining a clean and accurate Registry database, conducting statistical analyses on program evaluation and ALS epidemiology in Massachusetts, assisting in the preparation of statistical reports, attending public meetings, and working with other technical staff on special studies. Other duties will include organizing annual advisory committee meetings and collaborating with other Bureau of Environmental Health (BEH) staff in the design and implementation of other environmentally-related chronic disease surveillance systems. This position requires strong organizational skills, excellent oral and written communication skills, and the ability to conduct basic statistical analyses using Access, Excel, and SAS.


Link: https://massanf.taleo.net/careersection/ex/jobdetail.ftl?job=1800040G&tz=GMT-05:00&src=JB-10080
Employer: Massachusetts Department of Public Health
Location: Boston, MA
Sector: Non-Profit
Degree required: BS or MS
Conditions: ALS
Job posted: July 5th, 2018
Massachusetts Department of Public HealthBoston, MABS or MSALSJul 05, 2018
Director, Registry Operations

Director, Registry Operations

(Click title to open job details in a new window.)
Description:

The Registry Operations Director will direct and manage operations for MDA’s large, multi-disease Neuromuscular Observational Research (MOVR) Data Hub, a key element of MDA’s mission to improve patient outcomes and help drive drug development. This position works across multiple departments within MDA and with external stakeholders including, but not limited to, industry, governmental agencies, academic institutions and other non-profit organizations to build and maintain the MOVR Data Hub. This position will report directly to the SVP, Scientific Program Director.


Link: https://mda.jobs.net/en-US/job/registry-operations-director/J3M1LZ6QC72Q5W1D3F9
Employer: Muscular Dystrophy Association
Location: Boston, MA
Sector: Nonprofit
Degree required: BS or BSN
Conditions: NDG
Job posted: May 8th, 2018
Muscular Dystrophy AssociationBoston, MABS or BSNNDGMay 08, 2018
Senior Scientist

Senior Scientist

(Click title to open job details in a new window.)
Description:

Sage Bionetworks is recruiting a scientist with bioinformatics or computational biology experience to lead integrative genomic analysis within multiple consortia of biologists and computational biologists studying neurodegenerative and neuropsychiatric diseases.


Specific Responsibilities Include:


Job responsibilities include facilitating research between teams of scientists.  Including  implementing  analyses, coordination of consortium-wide analyses, and cross-project evaluation and integration of results. These projects will advance our molecular understanding of neurodegenerative and neuropsychiatric disease biology to eventually refine disease diagnoses or targeted therapeutic intervention.


Specific responsibilities will focus on leading efforts in analysis of primarily genomic data through the following activities:


•     Perform research through well-informed biological and methodological strategic decisions on analyses of genomic and/or imaging datasets.


•     Develop novel mechanisms to evaluate and combine outcomes across multiple lines of biological and statistical evidence


•     Develop visualizations


•     Create scientifically rigorous publications, communications and presentations


•     Lead integrated analytical efforts and interpretation of results across collaborators within consortia


•     Work with a high-degree of independence to complete and publish high quality research in a transparent, reproducible manner.


•     Coordinate data deposition and analytical outputs across multiple researchers


•     Utilize internally developed software tools to manage collaborations and work closely with the software team to provide feedback on the development of these tools.


Basic qualifications:


•     Ph.D. in bioinformatics, computational biology, genomics, computer science, statistics or relevant scientific discipline with 3+ years of relevant experience or MS with 5+ years of relevant experience.


•     Expertise in analyzing and interpreting at-least one of the high-throughput genomics data: next generation sequencing (DNA, RNA, methylation), SNP Arrays, mass spectrometry (proteomics, metabolomics).


•     Proficient in at least one of following programming languages: R, Python, or Matlab


Additional skills/Preferences:


•     Extended knowledge of statistical data analysis of genomic data


•     Track record of innovative publications in application of or methodological development of integrative analysis of high-dimensional data.


•     Expertise with integrative, mechanistic, network, and/or predictive modeling


•     Domain knowledge in neurobiology, neuropsychiatry or inflammatory disease.


•     Outstanding  ability to manage a cross-disciplinary group of researchers in a collaborative project


•     Experience communicating advanced scientific concepts to a broad audience


•     Experience with high performance compute or cloud computing


Link: https://sagebase.clearcompany.com/careers/jobs/567fa130-6578-58a9-f671-38e3fabbaf7b/apply?source=676017-CS-28397
Employer: Sage Bionetworks
Location: Seattle, WA
Sector: Nonprofit
Degree required: PhD
Conditions: NDG
Job posted: May 7th, 2018
Sage BionetworksSeattle, WAPhDNDGMay 07, 2018