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Professor, Neurochemistry

The professorship in neurochemistry will be placed at the Department of Biochemistry and Biophysiscs (DBB). Neurochemistry with molecular neurobiology is a predominant area of research and education at the department. Several research groups focus on molecular aspects of neurodegenerative mechanisms, studies of ion channels, neurotoxins, cellular differentiation, intra- and extracellular signal transduction and the blood-brain-barrier. A wide spectrum of analytical methods including biochemistry, bioinformatics, computational chemistry, biophysics and molecular biology are used and developed at the department. Other facilities at DBB include cell culture, MST, NMR, crystallography, cryo-electron microscopy, confocal microscopy and quantitative image analysis.

Research Assistant

Applications are invited for the post of Research Assistant working on an exciting project which aims to improve the way in which the NHS delivers respiratory therapies, such as non-invasive ventilation (NIV), to patients with motor neurone disease (MND). You will work on Work Packages 2, 3 and 4 of this project. Work Package two involves carrying out a survey to explore current clinical practices and standards relating to the use of NIV in MND in the UK and in similar services to the NHS within Europe. Work Package 3 involves carrying out stakeholder consultations to explore and contextualise the research findings from previous Work Packages and to gain input about how best to translate them into clinical practice. Work Package 4 focuses on creating and testing a practical information toolkit to support the practice of healthcare professionals involved in the respiratory management of MND patients.

Group Leader, Big Data Neuroscience

Can you develop a productive and innovative research program and establish an independent research group through a combination of core funding and extramural funding? Can you complement the research program of the NIN by working in close collaboration with other research groups at the institute? And do you have a clear vision on how to approach the current challenges in one of the three neuroscience research fields described below? Then this job may be for you.

Research Associate, McDermott Lab

We are seeking an outstanding early-career researcher with the potential to become a leader in the field of mixed-methods health services research. You will join the research group of Professor Christopher McDermott at the Sheffield Institute for Translational Neuroscience (SITraN) to work on clinical research projects focusing on the supportive and symptomatic management of patients with motor neurone disease (MND) and other neurodegenerative disorders.

Research Assistant

We are seeking a research assistant to produce proteins related to the ALS (Motor Neuron disease), as part of an international project to generate high-quality antibodies for therapeutic research.

Postdoctoral Fellow, Van Damme Lab

The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains.

Assistant Professor

The Department of Biology at the University of Massachusetts, Amherst invites applications for a tenure-track position at the rank of Assistant Professor. The successful candidate will be a part of the Institute for Applied Life Sciences (IALS), which has a primary goal of developing translational research programs and fostering interactions with industry.

Assistant Professor of Neurology

The Center of Image Acquisition (CIA) at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute seeks a qualified applicant for an Assistant Professor (tenure track) position in the USC Department of Neurology. The CIA serves as central resource for the development and application of advanced imaging for all neuroimaging research at the Keck School of Medicine of USC. The CIA will interact and collaborate with many departments at the Health Sciences Campus and the University Park Campus conducting research in methodology and its application in the study of normal, neurological and psychiatric cohorts. The ideal candidate should have a Ph.D. in Biophysics, Biomedical Engineering, or a related field, and have 2-3 years of postdoctoral training in the field of MRI physics and its applications in neuroscience. The candidate is expected to develop innovative MRI techniques, in particular noninvasive blood flow and perfusion imaging. The main duties of this position include the development of an independent and/or collaborative research program and participation in multidisciplinary research applying novel MRI imaging techniques for assessing and diagnosing neurovascular and neurodegenerative diseases. Experience on pulse sequence programming, particularly on Siemens platform is highly desirable.

Assistant Professor, Biological Chemistry and Pharmacology

The Department of Biological Chemistry and Pharmacology, in the College of Medicine at The Ohio State University, invites applications from investigators using zebrafish as a model organism for a tenure-track faculty position at the rank of Assistant Professor. The successful candidate will join a vibrant and cohesive zebrafish community at The Ohio State University. The department has complementing strengths in motor neuron disorders, neuromuscular biology, RNA biology and epigenetics. There is also a college-wide program to enhance research in neurodegenerative diseases. Research programs that are in neurodegeneration or complement department strengths are particularly encouraged.

Assistant Professor, Biological Sciences

The Department of Biological Sciences in the School of Natural Sciences and Mathematics at the University of Texas at Dallas (http://www.utdallas.edu/biology/) invites applications for a faculty position at the rank of Assistant Professor. We seek to hire an outstanding scientist with research interests that complement and build on existing departmental strengths in biochemistry, cell and molecular biology, computational and systems biology, genomics, microbiology, and pathobiology (cancer, neurodegenerative disorders, and infectious disease). Since the department has the goal of expanding its research and teaching into new directions, we will also consider applications from excellent candidates in other areas of the biological sciences. Review of applications will begin immediately and will continue until the position is filled.

Assistant Professor, Developmental and Translational Neurobiology

The Virginia Tech Carilion Research Institute (VTCRI) has launched a new center within the institute – the Developmental and Translational Neurobiology Center (DTNC; https://wp.vtc.vt.edu/dtnc/), to expand the institute’s research programs in cellular and molecular neurobiology in healthy development, disease, and trauma. There are currently two open assistant professor faculty positions – one for a neurobiologist studying mechanisms underlying brain development or neurodevelopmental disorders and one for a neurobiologist or neuro-immunologist studying neurodegenerative disease or brain injury. Applicants should have an earned doctorate, have completed postdoctoral training and demonstrated a track record of successful research, publications and either active extramural funding (preferably from NIH) or show distinct promise to obtain such funding. The new faculty will join a collaborative and highly successful group of investigators at the VTCRI with related research interests in a variety of areas of neuroscience. Competitive salary, space and start-up packages will be provided.

Assistant Professor, Developmental and Translational Neurobiology

The Virginia Tech Carilion Research Institute (VTCRI) has launched a new center within the institute – the Developmental and Translational Neurobiology Center (DTNC; https://wp.vtc.vt.edu/dtnc/), to expand the institute’s research programs in cellular and molecular neurobiology in healthy development, disease, and trauma. There are currently two open assistant professor faculty positions – one for a neurobiologist studying mechanisms underlying brain development or neurodevelopmental disorders and one for a neurobiologist or neuro-immunologist studying neurodegenerative disease or brain injury. Applicants should have an earned doctorate, have completed postdoctoral training and demonstrated a track record of successful research, publications and either active extramural funding (preferably from NIH) or show distinct promise to obtain such funding. The new faculty will join a collaborative and highly successful group of investigators at the VTCRI with related research interests in a variety of areas of neuroscience. Competitive salary, space and start-up packages will be provided.

Assistant Professor, Genetics

The Centre for Integrative Biology of the University of Trento invites candidates active in Genetics to apply for a position at the Assistant Professor level. The position is offered for a three-year period. The annual gross salary will be about 45.000 Euros. The area of research and teaching is Genetics:

Assistant Professor, Mechanisms of Neurological Disease

The Department of Cell Biology at Emory University School of Medicine seeks outstanding applicants to fill a tenure-path faculty position at the Assistant Professor level in the areas of Neurological Disease, including Neurodevelopmental Disorders or Neurodegeneration.

Assistant Professor, Neural Biology

The Department of Biological Sciences at Augusta University anticipates a tenure-track position at the rank of Assistant Professor beginning in August 2018. The Department is composed of 22 full-time and 7 part-time faculty members with expertise across a broad spectrum of biological disciplines. We have a strong commitment to providing research opportunities and experience to our undergraduate students in addition to excellent classroom and laboratory instruction. As a thriving unit in this research university, faculty in the Department of Biological Sciences have both the opportunity and the expectation to help develop new undergraduate and graduate programs in the biological sciences. Within the next academic year, we expect to launch our first master’s program in Biomolecular Sciences and the faculty member hired for this position will be an integral part of this emerging program.

Assistant Professor, Neurobiology

Applications are invited for a position at the level of tenure-track Assistant Professor. The Department of Neurobiology and Behavior is ranked as one of the top neuroscience departments in the country and engages in interdisciplinary approaches to the study of neurobiology. The Institute for Memory Impairments and Neurological Disorders is home to one of 31 Alzheimer’s Disease Research Centers funded by the National Institutes of Health. We seek outstanding candidates whose research addresses the molecular neuropathology of Alzheimer’s disease and other neurodegenerative disorders. Preference will be given to applicants whose research integrates cutting edge neuroscientific techniques using human and animal tissue.

Assistant Professor, Neurobiology

The Virginia Tech Carilion Research Institute (VTCRI) (http://research.vtc.vt.edu) is recruiting several faculty in cellular and molecular neurobiology at the assistant professor level. The faculty will be recruited into two new centers (http://research.vtc.vt.edu/centers/) within the institute – the Developmental and Translational Neurobiology Center and the Glial Biology in Health, Disease, and Cancer Center. The faculty members will have tenure track appointments in an appropriate department and college at Virginia Tech.

Assistant Professor, Neuroinflammation Research

The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to study neuroinflammation and complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/).

Assistant Professor, Neurology

The USC Stevens Neuroimaging and Informatics Institute (INI) seeks highly-qualified applicants for the position of Assistant Professor (tenure-track). The successful applicant will have a minimum 5+ years experience (post doctoral degree) in imaging in aging and neurodegenerative diseases. A particular emphasis on functional and structural connectivity in Alzheimer’s disease is desired. The candidate should have specific interest in mechanistic processes of aging include neuroinflammation, and/or genetics. A strong foundation in understanding the role of imaging, genetics, and clinical phenotypes in characterizing age- and disease-related phenomena is desired. The candidate should have a PhD in Neuroscience, Psychology, or other related disciplines; a strong foundation in neuroimaging and 5+ years post-PhD research experience with a successful publication record and teaching experience is required. The applicant must demonstrate an ability to work with a highly collaborative and multidisciplinary team. Further, the applicant must have demonstrated a strong track record of obtaining independent funding to support a research program.

Assistant Professor, Neuroscience

In a major Neuroscience initiative, we seek to hire up to 2 tenure-track or tenured faculty members as part of a cross campus multi-disciplinary effort to study the nervous system (from development, to function, to aging, degeneration and repair). We seek researchers that collectively span multi-disciplinary levels of investigation (molecular mechanisms, circuit analysis, complex animal and human behaviors) using state of the art techniques (molecular, optogenetics, behavioral, educational, computational, imaging, EEG, genetic and research of clinical populations) applied to experimental model systems of health, injury and disease (invertebrate, vertebrate or human systems). Our goal is to recruit a team of collaborative individuals with an outstanding record, committed to excellence in research, that complement existing campus strengths. Applicants for tenured positions should also demonstrate notable scientific contributions and sustained extramural support. Successful candidates must also have clear potential or demonstrated ability to work successfully with and benefit a diverse student body.

Assistant Professor, Neuroscience and Cell Biology

Specific Job Related Duties

Assistant Professor, Pharmacology and Chemical Biology

Beginning immediately, we seek investigators who will develop independent and vigorous research programs in any area of pharmacology and chemical biology. Individuals with demonstrated research interests and accomplishments in chemical biology, molecular pharmacology, systems pharmacology, as well as innovative approaches for therapeutic discovery and disease biology are encouraged to apply.

Assistant Professor, Pharmacology and Chemical Biology

The Department of Pharmacology at the Emory University School of Medicine invites applications for tenure-eligible Assistant Professor positions. Applicants for other ranks will also be considered. Beginning immediately, we seek investigators who will develop independent and vigorous research programs in any area of pharmacology and chemical biology. Individuals with demonstrated research interests and accomplishments in chemical biology, molecular pharmacology, systems pharmacology, as well as innovative approaches for therapeutic discovery and disease biology are encouraged to apply.

Assistant or Associate Clinical Professor

The candidate should have areas of specialty interest that would mesh well with existing priorities that include cerebrovascular diseases, neurodegenerative diseases, movement disorders, or epilepsy, but candidates with expertise in other areas will also be considered.  The ideal candidate will have finished a residency plus a Neurology fellowship. The successful candidate will receive start up funding, dedicated research time to build a world-class research program and have a strong interest in an academic career. This is a tenure track position.

Assistant or Associate Professor

The Department of Cellular Biology and Anatomy, Medical College of Georgia, at Augusta University is undergoing an expansion of its research program and is seeking tenure-track faculty at the Assistant or Associate Professor levels. Academic rank will be commensurate with experience. The department is seeking candidates with an interest and expertise in diseases associated with aging. Preferential consideration will be given to investigators with research expertise related to Bone/Musculoskeletal, Renal, Visual or Neurodegenerative diseases, which will complement existing strengths within the department. Augusta University is the home of the only research-oriented, state-supported medical school in Georgia and offers an outstanding interdisciplinary environment. The research infrastructure includes state-of-the-art core facilities for confocal, multi-photon and super-resolution imaging, small animal behavior/imaging, proteomics, genomics including high throughput Illumina sequencing, flow cytometry, and electron microscopy/histology. Candidates at the Assistant Professor level must demonstrate a strong potential for research including obtaining extramural funding. Candidates at the Associate Professor level must possess external funding at the NIH R01 level and demonstrate potential for its continuation. The successful candidate will receive a nationally competitive start-up package, be expected to establish and maintain an extramurally funded research program, and participate in teaching. Applicants should submit a curriculum vitae, a statement of research objectives, a description of teaching interests/experience, and identify at least three individuals as references.

Assistant or Associate Professor, Neuropathology

The Division of Neuropathology in Department of Pathology at Brigham and Women’s Hospital, a teaching affiliate of Harvard Medical School, is seeking an academically oriented, Board-certified Neuropathologist, at the Instructor, Assistant or Associate Professor level, with skills in surgical and autopsy neuropathology. Academic rank and salary will be commensurate with experience and accomplishments. Applicants should be committed to excellent patient care, as well as research, scholarship, and effective teaching. Experience or ability to participate in precision medicine and molecular pathology is preferred. Pathologists with academic focus in neurodegenerative, tumor, medical or any other areas of neuropathology expertise are encouraged to apply. The position will combine clinical duties and academic pursuits (research/teaching) and will be involved in the Longwood Neuropathology Training Program that includes the accredited fellowship program in adult and pediatric surgical and autopsy neuropathology at the Brigham and Women’s Hospital, Dana-Farber Cancer Institute and Children’s Hospital Boston. Candidates would be expected to take advantage of the extensive resources and collaborative interactions within the Brain Tumor Research Program, the Ann Romney Center for Neurologic Diseases, and the Neuroscience Programs of the Harvard Medical School, Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and The Children’s Hospital Boston. Applicants should also have the ability to lead or participate in research in an environment that provides substantial opportunities for clinical/ translational or basic research.

Assistant or Associate Professor, Neuroscience

The Albert Einstein College of Medicine (Einstein), together with the Montefiore Medical Center, has launched an ambitious Brain Sciences Initiative. As part of this large-scale expansion, the Dominick P. Purpura Department of Neuroscience has recruited a number of outstanding faculty, and will continue to recruit additional faculty in the coming years.

Assistant or Associate Professor, Neuroscience

We are seeking individuals with research interests that complement our existing programs related to biological mechanisms and modeling of neurodegenerative diseases. Of particular interest are programs with a focus on Alzheimer’s Disease, Frontotemporal Dementia, and Parkinson’s Disease. Candidates with expertise and documented productivity in research areas that include investigation of how unfolded protein responses contribute to these diseases, with particular focus on tauopathies, are preferred. Candidates must have a desire to expand the educational landscape of the Department of Neuroscience through teaching and research training program development.

Assistant or Full Professor, Chemical Biology

Sanford Burnham Prebys Medical Discovery Institute (SBP) is an independent non-profit biomedical research institute that blends world-class fundamental research with drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders. The Institute invests in talent, technology, and partnerships to accelerate the translation of laboratory discoveries that will have the greatest impact on patients. Recognized for its world-class NCI-designated Cancer Center and the Conrad Prebys Center for Chemical Genomics, SBP employs more than 1,100 scientists and staff in La Jolla (San Diego), California, and Lake Nona (Orlando), Florida.

Assistant, Associate and Full Professor, Neuroscience

The Department of Neuroscience on the Jupiter, FL campus of The Scripps Research Institute (TSRI) is seeking outstanding applicants for tenure track faculty positions at all levels. We invite applications from ambitious and interactive investigators from all areas of modern neuroscience applying molecular, genetic, biochemical, biophysical, cellular anatomical, and behavioral approaches to elucidate the mechanisms underlying nervous system function and its disorders.

Assistant, Associate or Full Professor, Biomedical Sciences

The UTRGV School of Medicine is seeking Faculty members at the Assistant, Associate or Professor level experienced in research in Biomedical Sciences. The background should be in all disciplines of biomedical sciences including endocrine and metabolic diseases (such as diabetes and obesity), neuroscience and neurodegenerative diseases, cancer or oncology research and research in infectious diseases. The selected individuals will carry out high quality research projects and are expected to successfully acquire extramural research support. Laboratory space, competitive salary and start-up packages are available. Postdoctoral research experience in a top-rated research program is preferred.

Assistant, Associate or Full Professor, Chemical Neuroscience

The Department of Medicinal Chemistry at the University of Minnesota invites applications for a tenure-track faculty position at the rank of Assistant, Associate, or Full Professor level. The Department is housed in the College of Pharmacy (CoP), which is ranked #2 in the Nation as a Top Pharmacy School and #3 in research funding among its peers. The position will be a twelve-month full-time appointment, with expectations in teaching (in the areas of Medicinal Chemistry & Neuroscience) and service to both the PharmD professional curriculum and also the Departmental graduate education programs. Candidates are expected to establish, maintain, and direct a major research program addressing chemical neuroscience from a medicinal chemistry/chemical biology perspective to interface with other activities within the University of Minnesota, the CoP, and the Institute for Translational Neuroscience (https://www.med.umn.edu/research/research-strengths-expertise/neuroscience/institute-translational-neuroscience ). Emphasis is placed on research in neurodegenerative disorders, epilepsy, psychiatric diseases, neuroaddiction, and neuroendocrinology, but all neuroscience sub-disciplines are encouraged to apply. Interested candidates are strongly encouraged to apply by December 15, 2016 for the first review; however, this position will remain open until filled.

Assistant, Associate or Full Professor, Environmental Health

The Department of Environmental and Occupational Health (EOH) within the Robert Stempel College of Public Health & Social Work (RSCPHSW) at Florida International University (FIU) invites applications for two tenured/tenure-track faculty member at the Assistant/Associate/Professor rank (rank and tenure commensurate with qualifications).

Assistant, Associate or Full Professor, Molecular Pharmacology & Physiology

The Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine invites applications for tenure-track faculty positions at the Assistant/Associate/Full Professor levels. A doctoral degree in medical or biomedical sciences is required. Applicants must demonstrate a strong record of academic accomplishments with NIH-supported research programs. Expertise in neuroscience, cardiovascular, splanchnic organ system, metabolism and inflammation/immunology research areas is preferred, with an emphasis on the study of molecular, cellular and systemic mechanisms. Applicants must also demonstrate a history of medical school teaching excellence and are expected to have outstanding verbal communication skills.

Assistant, Associate or Full Professor, Neurobiology

The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/). Qualified applicants holding Ph.D., M.D. or equivalent degrees will be considered for appointment at assistant, associate or full professor levels. The successful candidate will be expected to direct an extramurally-funded research program in neurodegenerative disease research using interdisciplinary approaches. Institutional strategic interests for this position are in Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and traumatic brain injury. Qualified applicants in other areas of translational neuroscience also will be considered. The successful candidate is expected to synergize/collaborate with existing research and clinical faculty, will have access to core facilities and clinical samples, and may leverage opportunities to collaborate with investigators at affiliate institutes including Phoenix Children’s Hospital, the Translational Genomics Research Institute, and the University of Arizona. The successful candidate will receive a highly competitive start-up package and salary support.

Assistant, Associate or Professor, Pharmacology

The University of Southern California (USC) Titus Family Department of Clinical Pharmacy invites applications for a tenured/tenure track position at the rank of Assistant, Associate or Professor. Individuals with research interests in pharmacogenomics, pharmacometrics, bioinformatics, or medication safety are encouraged to apply.

Assistant, Associate, Full Professor, Pathology and Cell Biology

The Department of Pathology and Cell Biology at the Columbia University Medical Center seeks highly qualified individuals for faculty positions in surgical pathology, clinical pathology and research. Appointments can be at the Instructor, Assistant, Associate, Professor, or Associate Research Scientist level depending on experience and qualifications. All positions require outstanding academic credentials and a record of scholarly productivity. Clinical positions require board certification and a license in NYS. Columbia University’s Department of Pathology & Cell Biology invites applications for a junior/senior level faculty position. Candidates should have a strong record of research and teaching qualifications (distinction). Candidates will be expected to sustain an active research and publication portfolio and supervise graduate students, and fellows. Candidate will play a vital role in Departmental activities.

Associate Director or Senior Manager, Business Development and Alliance Management

In conjunction with and reporting to the Sr. Vice President of Business Development, the Senior Manager/Associate Director, Business Development and Alliance Management will focus on building value through strategic alliances and/or licensing transactions.

Associate Professor, Cognitive Neuroscience

The Department of Psychiatry & Behavioral Sciences and the Cognitive Neurology and Alzheimer’s Disease Center at the Northwestern University Feinberg School of Medicine are jointly searching for a cognitive neuroscientist. The successful candidate will have the credentials for a full-time tenure-track appointment (Investigator Track) at the level of Associate Professor. The candidate will have the capability to lead an independent laboratory on the experimental neuropsychology and multimodal imaging of neurodegenerative diseases and successful aging. Established track record of research achievements in these areas and expertise on the cognitive aspects of aging and dementia are desirable. The successful candidate will contribute to the academic mission of the Clinical Psychology Doctoral Program within the Department of Psychiatry and will lead his/her research program on dementia and aging within the Cognitive Neurology and Alzheimer’s Disease Center. The start date is negotiable and the position will remain open until filled.

Associate Scientist

Amgen is seeking an Associate Scientist to join the Neuroscience Department at our research facility in Cambridge, MA. The Associate Scientist will work independently and as part of cross-disciplinary teams. The Associate Scientist will join an energetic research team responsible for the design and execution of innovative assays and the production of high quality data with the goal of developing therapeutics for neurological disorders with an emphasis on Neurodegenerative Diseases (Parkinson’s disease, Alzheimer’s disease, and Amyotrophic Lateral Sclerosis).

Associate Scientist

The ALS Therapy Development Institute (ALS TDI) has an opening for a full-time Associate Scientist working in the Translational Research group. The Associate Scientist will be part of the team working to develop patient-derived induced pluripotent stem cell (iPSc) collection, as well as the development and implementation of cell-based high content screens for target and drug discovery.

Associate Scientist

Yumanity is seeking a talented and versatile BS/MS scientist to join our interdisciplinary team to help advance novel drug discovery programs for neurodegenerative diseases. This position will be laboratory based, and requires strong experimental skills with background in cell and molecular biology and experience in quantitative assay development. The successful candidate must be highly flexible and team-oriented. The position will report to a Principal Scientist in the Mammalian Assay Development group, and will interact across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification, stem cells and chemistry.

Associate Scientist

Yumanity is seeking an associate scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based and requires experimental skills in human stem cell culture, including experience differentiating patient and control-derived progenitor cells into various central nervous system cells. This position will report to a Senior Scientist in Discovery Biology and will collaborate across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry.

Associate Scientist II, ALS

The Department of Neurology Research is seeking a highly talented and enthusiastic associate to join an in vitro / in vivo target discovery and validation effort in Amyotrophic Lateral Sclerosis (ALS) aimed at bringing new targets and therapeutic strategies from discovery to development. The successful candidate will be expected to support efforts to develop and validate new in vitro ALS models for candidate identification and validate findings in primary mouse tissue.

Associate Scientist II, Neuroimmunology, Research

The Neuroimmunology department at Biogen is searching for a committed, enthusiastic and dependable associate scientist to assist with the design, execution and interpretation of preclinical studies for drug discovery and development. The incumbent will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative/neuroinflammatory diseases. He/she should be able to plan and execute in vivo and in vitro experiments with high level of independency, organization and scientific rigor. He/she should be able to maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members.

Associate Scientist III, ALS

The Department of Neurology Research is seeking a highly talented and enthusiastic associate to join an in vitro / in vivo target discovery and validation effort in Amyotrophic Lateral Sclerosis (ALS) aimed at bringing new targets and therapeutic strategies from discovery to development. The successful candidate will be expected to support efforts to develop and validate new in vitro ALS models for candidate identification and validate findings in primary mouse tissue.

Associate Scientist III, Neuroimmunology

The Biogen Department of Neuro/Immunology seeks a highly motivated and keen associate scientist whose primary responsibility is to advance target validation, drug discovery and development. The individual is expected to have mastered a broad range of experimental techniques, preferably having established expertise in the field of neuroimmunology. The individual will be expected to perform with significant independence with respect to designing and executing controlled experiments, analyzing and interpreting results, establishing and executing existing or new protocols/methodologies and recommending modifications. The individual is expected to read pertinent literature and exhibit knowledge of molecular and biological processes, applying their knowledge to propose new ideas and regularly make suggestions for creative solutions to technical challenges. The individual is expected to have strong written and verbal communication skills, preparing and delivering oral presentations, posters, draft research reports and contributing to manuscripts.

Associate or Full Professor, Neuroscience

In a major Neuroscience initiative, we seek to hire up to 2 tenure-track or tenured faculty members as part of a cross campus multi-disciplinary effort to study the nervous system (from development, to function, to aging, degeneration and repair). We seek researchers that collectively span multi-disciplinary levels of investigation (molecular mechanisms, circuit analysis, complex animal and human behaviors) using state of the art techniques (molecular, optogenetics, behavioral, educational, computational, imaging, EEG, genetic and research of clinical populations) applied to experimental model systems of health, injury and disease (invertebrate, vertebrate or human systems). Our goal is to recruit a team of collaborative individuals with an outstanding record, committed to excellence in research, that complement existing campus strengths. Applicants for tenured positions should also demonstrate notable scientific contributions and sustained extramural support. Successful candidates must also have clear potential or demonstrated ability to work successfully with and benefit a diverse student body.

Associate or Full Professor, Neuroscience

The Department of Neuroscience and Center for Brain Immunology and Glia at the University of Virginia are seeking candidates for tenure-eligible Associate and Full Professor positions.

Biocuration Scientist

The Biocuration Scientist is responsible for the ongoing curation of scientific databases and directories that serve the neurodegeneration research community. The databases reflect the breadth of AD research and include information on research models, mutations, biomarkers, therapeutics, and other aspects of research on AD and related disorders. The Biocuration Scientist collaborates with the scientific content manager and other Alzforum staff members to ensure that information is accurate, up to date, and consistent across the website.

Bioinformatician, Salomoni Lab

We are seeking an interactive and self-motivated Bioinformatician / Computational Biologist to join a team of cell and molecular biologists working on brain pathophysiology. The projects will focus on interrogating and integrating existing and new genetic and epigenetic datasets generated from genetically engineered mouse models as well as primary human samples. This programme of work is based on published/unpublished work from the team. This work will be conducted by Professor Paolo Salomoni whose research interest is nuclear function in regulation of cell fate in normal brain and CNS disease.

Bioinformatician, Single Cell Bioinformatics

The VIB-KU Leuven Center for Brain & Disease Research is located in Leuven, Belgium, and part of VIB and the University of Leuven (KU Leuven). With more than 300 people working in 17 labs, we study the brain in health and disease. Our research focuses on disorders such as Alzheimer’s, Parkinson’s, frontotemporal dementia and amyotrophic lateral sclerosis (ALS), but also basic research questions relating the cellular heterogeneity of the brain, brain wiring and synapse biology. These studies are integrated with immunology and studies on protein aggregation and amyloid toxicity.

Biologics Group Leader

The Biotechnology Discovery Research (BioTDR) Lead Generation is looking to fill a position for an experienced researcher to lead a drug discovery group passionate about discovering and enablement of large molecule drugs to combat diseases in the immunology, diabetes, oncology, neurodegenerative and pain areas. Are you a highly skilled scientist who has demonstrated ability to facilitate communication between multidisciplinary teams, coordinating complex cross-functional teams? Are you prepared to lead productive collaborations both within BioTDR, and with therapeutic area partners as well as clinical colleagues so as to identify and develop opportunities for protein therapeutics? You will participate in ongoing research projects as well as initiate new drug discovery research efforts. You should be able to work in an interdisciplinary setting, have detailed understanding of disease pathophysiology and drug hunting experience.

Biostatistician, Research Fellow

Applications are invited for a motivated and self-driven individual for the position of Biostatistician with the Irish ALS Research Group, hosted in the Trinity Biomedical Sciences Institute’s Academic Unit of Neurology. This project will combine high resolution structural and dynamic imaging of the brain at 3 Tesla and spectral EEG/ EMG with clinical and genomic data to identify sub-clusters of ALS patients.

CNS Pre-Clinical Research Lead

The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for:

Chair, Department of Neuroscience

The UConn School of Medicine is seeking an outstanding neuroscientist at a rank of Associate or Full Professor to become Chair of the Department of Neuroscience. Candidates with nationally recognized accomplishments in research, sustained NIH or extramural funding, and leadership experience are encouraged to apply. Desired areas of expertise include but are not limited to cellular and molecular neuroscience, chronic and neurodegenerative diseases, brain circuitry research, and neurogenesis and regeneration. This position is ideal for an energetic individual with the leadership skills and vision required to foster the health and growth of a department that values academic excellence and collaboration. The departmental faculty excel in a variety of research areas (neuroscience.uchc.edu), lead educational programs in the graduate, medical and dental schools, and provide a stimulating environment for research trainees.

Chair, Department of Neuroscience

The UConn School of Medicine is seeking an outstanding neuroscientist at a rank of Associate or Full Professor to become Chair of the Department of Neuroscience. Candidates with nationally recognized accomplishments in research, sustained NIH or extramural funding, and leadership experience are encouraged to apply. Desired areas of expertise include but are not limited to cellular and molecular neuroscience, chronic and neurodegenerative diseases, brain circuitry research, and neurogenesis and regeneration. This position is ideal for an energetic individual with the leadership skills and vision required to foster the health and growth of a department that values academic excellence and collaboration. The departmental faculty excel in a variety of research areas

Chair, Department of Translational Neurosciences

The University of Arizona College of Medicine – Phoenix is seeking an inaugural Chair for its new Department of Translational Neurosciences (TNS). TNS will be a novel medical school department, one that actively bridges basic science and clinical medicine through innovative collaborative research programs. The Chair will have the opportunity to create the overarching vision and, through strategic leadership, to build a center of translational neuroscience excellence. The Department Chair will have resources to recruit TNS faculty who will enhance our University of Arizona Health Sciences (UAHS) scientific community. We seek a visionary leader with expertise in molecular, cellular, or genetic approaches to neuroscience whose research is motivated by the challenges of nervous system disorders and directed toward advancing clinical care and improving human health in the foreseeable future.

Chair, Neurological Sciences

The College of Medicine at Florida State University has embarked on a strategic effort to increase basic and translational research in human neuroscience. In an effort to extend our impact in neural health, we are seeking applications for the College of Medicine’s Mina Jo Powell Chair in Neurological Sciences.

Chief of Staff, VA

VA Puget Sound Health Care System (VAPSHCS), located in Seattle, Washington, and the University of Washington (UW) are recruiting for a Physician to serve as their Chief of Staff to provide administrative, programmatic, and clinical leadership for the medical center.

Clinical Assistant Professor, Neuropsychology

The Neuropsychology Section in the Department of Neurology at the Indiana University School of Medicine and Indiana University Health Physicians has an immediate opening for an Adult Neuropsychologist at the rank of Clinical Assistant Professor. The Section of Neuropsychology is situated in new space inside a unique, integrated clinical neuroscience center of excellence, comprising neurology, psychiatry, neurosurgery, and related services. Responsibilities will include coordination and provision of clinical assessment services, participation in multidisciplinary treatment teams, supervision of pre- and postdoctoral trainees and staff, and participation in the overall academic mission (including lectures to neurology residents). Major patient populations include neurodegenerative diseases, movement disorders, epilepsy, oncology, and brain injury, as well as a broad range of complex medical disorders. Although primarily a clinical position, there are significant opportunities for participation in research, including brain imaging work in alcoholism risk, Alzheimer disease, stroke, epilepsy, etc. Requirements include post-doctoral training in clinical neuropsychology and eligibility for licensure in Indiana. Preference will be given to ABPP-eligible or already board certified clinicians experienced with the above patient populations. Applications will be considered until the position is filled. Indiana University is an EEO/AA Employer, M/F/D. Qualified candidates should submit a letter of career goals and interests and a current CV to: http://indiana.peopleadmin.com/postings/5050

Clinical Cognitive Neuroscientist

Cognitive Neuroscience at the University of Nebraska Medical Center. The Department of Neurological Sciences at the University of Nebraska Medical Center invites applications for a tenure leading faculty position in Clinical Cognitive Neuroscience. This position is part of a new Neuroimaging Section within the department and aims to leverage multiple hires across the School of Medicine in human neuroscience. We welcome applications from any area of cognitive neuroscience, including memory, executive function, visual attention, perception, audition, motor control, emotion, and decision-making. Methodological specialty within neuroimaging is open, but ideally the candidate would benefit from our strong existing program in MEG imaging, and develop a translational, theory-based multimodal neuroimaging program focusing on their area of interest. The successful applicant would join a growing group of cognitive neuroscientists within the department (and across campus) using MEG, fMRI, and other modalities, and hopefully help grow other programs in parallel with building their own.

Clinical Coordinator

The Division of Neuromuscular Disorders is seeking a Research Support Coordinator to join a very active clinical research program with multiple ongoing research studies. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). The research support coordinator will work closely with clinical research coordinators, data manager, statistician, clinical staff and the principal investigator.

Clinical Psychologist

We are seeking a Clinical Psychologist with a strong interest in neuroscience and experience in neuropsychological assessment to join a well-established multidisciplinary neuroscience team specialising in early onset and/or rare dementias.

Clinical Research Coordinator

Cedars-Sinai Department of Neurology neuromuscular group is looking for an experienced Clinical Research Coordinator to join their research team. We are currently recruiting for over 10 protocols which include repositories, natural history studies, and interventional trials including pharmacological and surgical approaches.

Clinical Research Coordinator

The University of Miami’s Division of Neuromuscular Disorders in the Department of Neurology is seeking a full time Clinical Research Coordinator. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). To effectively perform in this position, the Clinical Research Coordinator will ideally have experience working on investigator-initiated clinical research projects, to be able to work independently with minimal supervision and to function effectively as part of a team.

Clinical Research Fellow, Neuromuscular Diseases

We now offer a unique opportunity to an academic clinical neurologist to join our team as a Clinical Research Fellow in Neuromuscular Diseases. During a negotiable 1-2 year commitment based at Cytokinetics’ offices in South San Francisco, the Fellow will contribute invaluable expertise to our clinical development programs in neuromuscular diseases. The Fellow will benefit from an experience rarely available in a strictly academic position; i.e., the day-to-day leadership and management of a clinical trial aimed at the development of new therapeutics for patients. The Fellow may engage in this opportunity in the context of their academic fellowship as a means to satisfy a research requirement if agreeable to their institution. Continued involvement in the clinical management of patients during the period of this fellowship will be encouraged. The Fellow may return to his or her academic post at the conclusion of the term, enriched by this experience in addition to returning to the parent institution with a portfolio of valuable clinical research competencies.

Cognitive Clinical Research Nurse

The Cognitive Clinical Research Nurse is responsible to promote organizational values of patient and visitor satisfaction by demonstrating courtesy and respect for families, visitors and other employees. Cares for patients in all age groups from young adult through geriatrics. Demonstrates competence in the assessment, treatment and care of patients serviced. Works in collaborative practice setting with supervising/collaborating physicians to care for patients within the Penn Frontotemporal Degeneration Center.

Computational Biologist

Verge Genomics is looking for a genomics scientist to develop algorithms, statistical methods, and software to analyze large-scale gene expression and genomic datasets. You will implement these methods to identify new disease targets and mechanisms, and drugs that target these disease gene networks. As one of the first employees at Verge, you will develop cutting-edge methods that will serve as the foundation of a revolutionary drug development model.

Data Analyst

This analyst will work under the guidance of investigators in the Center for Biomedical Image Computing and Analytics (http://www.cbica.upenn.edu/, CBICA), Director, Christos Davatzikos, PhD.

Director of Clinical Operations

At Alector, we believe that neurodegeneration and dementia, are in fact immune disorders and we made it our mission to empower the immune system to cure Alzheimer’s disease, frontotemporal dementia, ALS and other degenerative brain conditions. We are supported by leading investors in healthcare including Orbimed, Polaris, Google Ventures and count some of the most innovative pharma companies as our strategic backers.

Director of Neurodegeneration Disease Models

Alector is looking for exceptional scientists, senior scientists, and director-level investigators with a PhD and/or MD, an outstanding publication and track record, and a drive to innovate. The candidate must have extensive, hands-on expertise in conducting and managing disease model studies for neuro-degeneration and dementia, including Alzheimer’s disease, Parkinson’s disease, Frontotemporal dementia and ALS, in rodents. The successful candidates will play leading roles in the discovery and development of novel, disease-modifying drugs.

Director of Neurodegenerative Research

We are currently on the hunt for a Director of Research– Neurodegenerative to oversee all aspects of neurodegenerative gene therapy research at the GTP at PENN. In this role, you will be responsible for build a team of Senior Research Investigators (SRI) to support GTP’s Neurodegenerative research efforts; establishing processes for mentoring and leading SRIs in research projects; directly oversee and manage a team of SRIs and technicians; In consultation with the PI of the GTP, the Research Director – Neurodegenerative will assess the rare disease programs that are brought into GTP for scientific research. The individual should have in-vivo pharmacology expertise for preclinical translational programs as well as expertise in testing the efficacy of therapeutic interventions for neurodegenerative disease indications. Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures.

Director or Senior Director, Gene Transfer Technologies

The Director/Senior Director is a recognized expert in the science and applications of gene transfer and gene therapy. The incumbent will lead the Gene Transfer Technologies research group whose mission is to:

Director, Center for Neurodegenerative Disorders

The University of Maryland Department of Neurology is seeking a senior level physician scientist with expertise in dementia and neurodegeneration to serve as the Director of the Center for Neurodegenerative Disorders. Specifically, the Department is seeking an investigator with a strong history of external funding whose work focuses on the molecular and cellular pathogenesis of neurodegenerative disorders including Alzheimer’s disease (AD), Huntington’s disease (HD), Fronto-temporal dementia (FTD), or hereditary ataxias (HA).

Director, Center for Neurodegenerative Disorders (Physician-Scientist)

The University of Maryland Department of Neurology is seeking a senior level physician scientist with expertise in dementia and neurodegeneration to serve as the Director of the Center for Neurodegenerative Disorders. Specifically, the Department is seeking an investigator with a strong history of external funding whose work focuses on the molecular and cellular pathogenesis of neurodegenerative disorders including Alzheimer’s disease (AD), Huntington’s disease (HD), Fronto-temporal dementia (FTD), or hereditary ataxias (HA).

Director, Clinical Pharmacology

Reporting to the EVP Research & Development, the Director, Clinical Pharmacology will be responsible principally for early clinical drug development activities with a strong focus on Phase I and Phase IIa clinical trials. He/She will work closely with the Clinical Research Group and other members of the R&D team to ensure a strategic view is taken for the pipeline progression of individual projects.

Director, Division of Neuroscience

The National Institute of Neurological Disorders and Stroke (NINDS) seeks a Director to lead its extramural Division of Neuroscience. The Director of the Division of Neuroscience will be responsible for planning and directing a program of extramural and collaborative research in neuroscience, guiding NINDS’s largest research portfolio and charting the future of a vibrant, growing neuroscience research community https://www.ninds.nih.gov/. The Director of the Division of Neuroscience will lead a group of approximately 60 professional staff. The research portfolio of the Division of Neuroscience includes an annual budget of over $1 billion dollars in grants and over $30 million in R&D contracts.

Director, Institute of Biotechnology

Helsinki Institute of Life Science HiLIFE of the University of Helsinki is seeking a Director of the Institute of Biotechnology (bi.helsinki.fi). The Institute of Biotechnology (BI) is at the forefront of molecular biology research with eight current ERC grantees, and has a strong focus in biotechnology through developing new strategies e.g. to combat neurodegenerative and metabolic diseases. Current research programs at the BI are in Cell and Molecular Biology, Developmental Biology, Genome Biology, and Structural Biology and Biophysics. BI is an international, competitive and rewarding workplace, where the staff within the 25 research groups and 7 core facilities exceeds 250 and comes from 30 different countries. As of 2017 the Institute of Biotechnology is a unit of HiLIFE (www.helsinki.fi/hilife) and collaborates locally across life science units and organizations.

Director, Neurobiology

Verge Genomics is seeking a motivated and accomplished Director of Neurobiology with experience using in vivo pharmacology models to translate in vitro compound hits to optimized drug leads. You will lead in vivo studies to validate small molecule efficacy and minimize side effect potentials and establish proof of concept by the manipulation of gene targets to ameliorate or create disease models. The ideal candidate will apply a combination of his or her expertise in the etiology and treatment of ALS, Parkinson’s and Alzheimer’s disease, results from our cell-based screens, and animal studies you will lead to best apply gene networks to guide our drug discovery efforts. With knowledge of neuropharmacology and experience translating compound discoveries to CNS applications, this position offers the opportunity to help lead the neurobiology research program at an emerging biotech company.

Director, Neurodegenerative Disease Research, Cleveland Clinic

The Cleveland Clinic Department of Neurosciences and Neurological Institute are actively seeking a Director to head the Cleveland Clinic Neurodegenerative Disease Research Center. The Director will have the opportunity to lead, expand, and integrate basic, translational, and clinical research programs. Senior candidates with PhD and/or MD degrees and well-established, independently-funded research programs are encouraged to apply. The Department of Neurosciences, the Lerner Research Institute, and the Neurological Institute offer excellent research and core facilities, generous start-up funds, and ongoing operational support. Candidates should submit a curriculum vitae and a brief statement of research interests and vision for the Center via e-mail to nelsonc6@ccf.org.

Director, Neuropharmacology

The Neuropharmacology Research group is seeking independent and motivated scientists to join a newly established research team focused on the rapid progression of novel therapeutics to humans for neurodegenerative, neurobehavioral and neuromuscular diseases. The Director, Neuropharmacology will be responsible for establishing and leading a research pharmacology group responsible for developing and leading innovative approaches to the treatment of neurodegenerative, neurobehavioral and neuromuscular disorders. The candidate will be expected to lead their own research project, as well as oversee other drug development programs with the goal of building a robust and sustainable portfolio of candidates for clinical development. The candidate will also oversee the efforts and be responsible for guiding the career development of 6-10 scientists.

Director, Neuroscience Electrophysiology

Job Responsibilities Include:

Director, Neuroscience Research & Drug Discovery

Verge Genomics is seeking a motivated and highly accomplished “drug hunter,” responsible for directing, managing, and leading basic research and drug discovery efforts for neurodegenerative diseases and leading multidisciplinary project teams. This position offers the opportunity to grow and lead a drug discovery program at an emerging biotech from the ground up, while establishing important external partnerships. As a member of the early team at Verge, you will be deeply involved in key strategic decisions and in organization of the research & discovery team, and help build the foundation of a revolutionary drug development model.

Director/Senior Director of Neurodegeneration and Repair Research

We are looking for a talented leader to direct preclinical research in Dementia and Memory Disorders within the new Neurodegeneration and Repair Research Unit. In close partnership with the early clinical lead for within the same unit, the successful candidate will be responsible for delivering innovative drug candidates for proof-of-concept trials in AD, FTD and other memory disorders. He/she will lead the efforts of multiple research teams from early target discovery to late preclinical development and support the clinical trial strategy. We seek a candidate with knowledge of the biology of neurodegeneration and an outstanding track record in the field of drug development. He/she will succeed by collaborating closely with other Biogen scientists and clinicians in the areas of neurodegeneration, neuroimmunology and repair, as well as experts in the multiple therapeutic modalities – small molecules, antibodies, biologics, antisense oligonucleotides and gene therapy – in the Biogen portfolio. An innovative approach to biomarker and drug delivery strategies will also be required. We particularly seek candidates who have demonstrated strong scientific rigor while exploring novel pathways and mechanisms in humans and model systems and in leading multidisciplinary research teams. Demonstrated expertise in Alzheimer’s research and experimental models would be an advantage but is not required.

Director/Sr. Director, Neurodegeneration and Repair Research

We are looking for a talented leader to direct preclinical research in Dementia and Memory Disorders within the new Neurodegeneration and Repair Research Unit. In close partnership with the early clinical lead for within the same unit, the successful candidate will be responsible for delivering innovative drug candidates for proof-of-concept trials in AD, FTD and other memory disorders. He/she will lead the efforts of multiple research teams from early target discovery to late preclinical development and support the clinical trial strategy. We seek a candidate with knowledge of the biology of neurodegeneration and an outstanding track record in the field of drug development. He/she will succeed by collaborating closely with other Biogen scientists and clinicians in the areas of neurodegeneration, neuroimmunology and repair, as well as experts in the multiple therapeutic modalities – small molecules, antibodies, biologics, antisense oligonucleotides and gene therapy – in the Biogen portfolio. An innovative approach to biomarker and drug delivery strategies will also be required. We particularly seek candidates who have demonstrated strong scientific rigor while exploring novel pathways and mechanisms in humans and model systems and in leading multidisciplinary research teams. Demonstrated expertise in Alzheimer’s research and experimental models would be an advantage but is not required.

Electrophysiologist

The Musculoskeletal disease area research department at the Novartis Institutes for BioMedical Research (NIBR) in Basel, Switzerland, is looking for a Scientific Associate with excellent electrophysiology skills to join a highly motivated research team that aims to identify and develop therapies for neuromuscular diseases and peripheral neuropathies like amyotrophic lateral sclerosis and sarcopenia.

Executive Director, Clinical Research, Rare and Neurological Diseases

The Rare Disease Research Unit is looking for a talented senior physician scientist to join our team developing transformational new treatments in rare Neuromuscular, Neurodevelopmental and Neurodegenerative diseases using AAV gene therapy. This individual will focus on the challenging translational, clinical and regulatory problems presented by gene therapy in rare (often) pediatric indications, including natural history studies, novel endpoint development and clinical trial design. The candidate will be accountable for the delivery of translational and clinical development plans for AAV gene therapy programs in multiple rare neurological indications, and will be skilled in early clinical program design and conduct from pre-clinical stages to POC. Similar activities will be required for programs exploiting other treatment modalities. Experience and proven collaborative skills with basic and clinical scientists, investigators, regulators and safety functions are essential.

Faculty Position – Dept. of Neuroscience

The Department of Neuroscience at Mayo Clinic in Jacksonville, FL, is seeking outstanding candidates with dynamic research programs in neurobiology of disease and aging. The ideal candidate for this position will be an investigator with an innovative and dynamic research program that is directed at understanding the fundamental role of disease biology in neurodegenerative disease including Alzheimer’s disease, Parkinson’s disease, Frontotemporal dementia, and Amyotrophic Lateral Sclerosis. Specific areas of interest include cerebrovascular disease, CNS immunity, neurobiology of aging, stem cell biology, neurodegeneration and neuroregeneration across a range of neurological disorders. We are seeking a world-class researcher to participate in departmental and institutional initiatives emphasizing collaboration and team science.

Faculty, Department of Biopharmaceutical Sciences

The University of Illinois at Chicago, College of Pharmacy, Department of Biopharmaceutical Sciences (http://go.uic.edu/BPS) invites applications for an open rank tenure-track faculty position in the field of pharmaceutics, drug delivery, or therapeutic bioengineering. Of particular interest are candidates with training and research interests in the areas of biologics, biopharmaceutical processing, formulation, and delivery. Special attention will be given to candidates whose research complements and expands our research in the areas of cancer, neurodegenerative diseases and/or the human microbiome.

Genetic Counselor

Working in the Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital (MGH) the genetic counselor will collaborate with and support the Amyotrophic Lateral Sclerosis (ALS) multidisciplinary clinical research team. The incumbent must have prior genetic counseling experience and a desire to be a key component of a team working to define the field of ALS genetics research. The majority of work will remain in the research realm; however, there will be opportunity to assist with complex ALS cases within the MGH ALS Multidisciplinary clinic or MGH Brain Health Clinic.

Graduate Research Assistant

The laboratory is seeking a motivated Graduate Research Assistant to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis (ALS) and dementia. There is an increased focus on altered RNA processing as a central component of neurodegeneration in ALS and frontotemporal dementia. Our group explores the role of RNA alterations in neuronal death and uses splicing and expression profiles to identify therapeutic strategies that correct disease-linked gene expression events. The successful candidate will lead a research project using various cellular and animal models of ALS to explore disease mechanisms. Under the supervision of the Principal Investigator, the candidate will design and perform experiments, will participate to the scientific lab meetings and is expected to fully participate in the organization and joint upkeep of the laboratory. He/She will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, preparation of libraries for high throughput sequencing, and mammalian cell cultures. Experience in mouse handling and mouse histology is preferred. The individual must pay attention to details, be capable of working independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team.

Graduate Studentship

The project will focus on the composition and biological impact of protein aggregates in ALS throughout the evolution of the disease and among the different types of the disease (e.g. C9ORF72-related ALS). To identify steps of different types of protein aggregate maturation human brain samples will be analyzed biochemically and neuropathologically. The biological effects (e.g. on nucleocytoplasmic transport) and toxicity of the aggregates will be tested in cell culture systems of human-derived induced pluripotent stem cells (iPSCS).

Graduate Studentship

We are looking for highly motivated candidates to explore the role of C9ORF72 in neurodegeneration associated with amyotrophic lateral sclerosis (ALS). ALS is a motor neuron disease characterised by progressive injury and death motor neurons in the brain and spinal cord. Recent reports suggest that C9ORF72 hexanucleotide intronic repeat expansion cause ALS with high prevalence in both familial and sporadic cases. The C9ORF72 gene is located on chromosome 9p (9p21) and encodes twelve exons, with three transcription variants, and two possible protein isoforms, termed a and b. The normal expansion typically comprises a fewer than 30 of GGGGCC repeats. Pathogenic expansions consists of hundreds to thousands repeats. RNA foci are observed in fibroblasts and CNS of patients with C9ORF72 expansion, suggesting defects of RNA metabolism. Despite the significant progress in C9orf72 research, the exact function of the C9orf72 protein remains unclear. Thus, further research efforts aimed at better understanding the role of C9ORF72 protein are of the utmost importance to enable therapeutic development for ALS.

Graduate Studentship, Basso Lab

The major focus of the project is on extracellular vesicles and motor neuron degeneration with a particular interest on the role of RNA in the glia-motoneuronal intercellular communication. The PhD student will acquire expertise on extracellular vesicles analysis, RNA profiling in the field of neurodegeneration.

Graduate Studentship, De Vos Lab

Applications are now being invited for a three-year Basic Science PhD Studentship funded by Alzheimer’s Society, starting in October 2017. The successful candidate will join an established training programme at the Sheffield Institute for Translational neuroscience (SITraN) in the group of Dr Kurt De Vos. Expansions of a noncoding GGGGCC hexanucleotide repeat in the C9ORF72 gene are the most common genetic defect found to date in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). How the repeat expansion causes disease is not known, but appears to involve both loss-of-function (C9ORF72 haploinsufficiency), and gain-of-function (repeat-associated non-ATG (RAN) translation, RNA toxicity) mechanisms. To unravel the ways in which C9orf72 expansions cause disease it is crucial to understand the normal functions of the C9orf72 protein. In this project we will investigate how the cellular levels of C9orf72 are regulated and leverage this knowledge to devise novel therapeutic strategies. Candidates must have a first or upper second class honors degree or significant research experience.

Graduate Studentship, Kadener Lab

We are looking for a highly motivated student to investigate the contribution and role of circular RNAs (circRNAs) in the development of neurodegenerative diseases. The student will join the Kadener lab in Jerusalem, a multidisciplinary team studying the role of circRNAs in physiology and disease in Drosophila. The position is part of circTrain (https://circtrain.eu/) an EU-funded International Training Network (ITN) that focuses on different aspects of circRNA biology.

Graduate Studentship, Maudsley Lab

The aim of this project is to disentangle the converging molecular pathomechanisms in the frontotemporal dementia – amyotrophic lateral sclerosis spectrum. We will pursue this goal by investigating different mouse models using state-of-the-art proteomic and transcriptomic technologies. Using this approach, we intend to unravel the disease mechanisms already at presymptomatic stages.

Graduate Studentship, Vande Velde Lab

Dr. Christine Vande Velde is looking to recruit a graduate student to her laboratory located at the CRCHUM facility, a research center affiliated with the Université de Montréal and located in Downtown Montreal.

Group Leader, Translational Biomarkers

Denali Therapeutics is seeking to recruit a Group Leader to lead the company’s translational biomarker efforts. S/he will be responsible for leading translational biomarker strategies and developing and implementing biomarker assays to assess the target engagement and PK/PD/response relationships of drug candidates in both preclinical models and clinical trials.

Head of Translational Science

The University of Texas Southwestern Medical Center, Center for Alzheimer’s and Neurodegenerative Diseases (CAND), is seeking applications for a faculty position as Head of Translational Science. Responsibilities include supporting the translation of novel targets and inventions into viable drug development and/or patient care solutions, engaging with Principal Investigators (PI’s), postdocs, and students to advance inventions from CAND laboratories, advancing high-throughput screening (HTS) hits into lead series, optimizing lead series to IND-ready clinical candidates, connecting entrepreneurs, bankers, and venture funds with CAND science, and utilizing Contract Research Organization (CRO) network to rapidly and cost-effectively advance CAND programs. Appointment rank will be commensurate with academic accomplishments and experience.Candidates must have a Ph.D. in chemistry, life sciences or a related discipline, practical experience in advancing drug programs into the clinic and validation of novel targets with in vivo proof of concept experiments.Desired skills include medicinal chemistry and DMPK expertise, hit and lead series evaluation, competitive analysis of programs, intellectual property path advisement, ability to connect CAND PI’s with resources such as CRO’s for chemistry and pharmacology, on-campus capabilities and UT System resources, grant writing, and design and interpretation of clinically relevant PI/PD experiments.

Junior or Senior Group Leader

The Grenoble Institute of Neurosciences (GIN), an outstanding research center devoted to understanding brain functions and the development of innovative clinical therapies for neurological, neuromuscular and psychiatric disorders, is welcoming applications for positions as junior and senior group leaders in basic and/or clinical research.

Lab Manager

The position is for a Lab Manager to help facilitate all daily lab operations. The individual will report to a Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders. A successful candidate will have excellent communication skills, highly confident decision making ability, experience managing multiple projects and life sciences lab management, and embrace the highly dynamic environment.

Lab Manager, Neurosciences Clinical Research Unit

The position is responsible for, and critically important to Neurosciences Clinical Research Unit (NCRU), and Memory and Aging Center (MAC) investigators for the overall operational management of clinical research activities for the biospecimens processing lab. The Lab Manager has direct responsibility for implementing a diverse portfolio of processing protocols which include multicenter clinical trials (both NIH and industry-sponsored), local investigator-initiated clinical trials, and clinical research activities, including a clinical database and biorepository LIMS system.

Lab Technician, Grinberg Lab

The position is for a part time Lab Technician / Staff Research Associate I (SRA I) to assist the Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus ( see http://grinberglab.ucsf.edu). The candidate is expected to be open to learning new methods.

Medical Director

Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to the genetics and biology of neurodegeneration and the principles of translational medicine. In anticipation of the Company’s growth plans, Denali Therapeutics is seeking to recruit a Medical Director. The Medical Director will be responsible for design, implementation, monitoring, analysis, and reporting of clinical trials and will provide strategic leadership for development programs.

Neurobiology Research Associate II

Verge Genomics is seeking a Neurobiology Research Associate II to join the Drug Discovery team. This candidate will gain pharmaceutical industry experience in a cutting-edge academic lab in the SF Bay Area and at Verge Genomics headquarters in SF. The candidate will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative diseases. The candidate will conduct in vivo studies in mice, including neonatal intracerebroventricular injections, and drug administration by oral routes. Experience with stereotaxic surgery, gene therapy (AAV9 or ASO), behavioral observations, gait analysis, rotarod and grip strength, and genotyping are a plus. The ideal candidate will have excellent problem-solving skills and familiarity with statistical analysis. This position reports to a PhD Scientist. The candidate will also culture motor neurons differentiated from induced pluripotent human stem cells and aid in the design and development of cellular assays to identify genes and compounds for treating neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). The candidate will have extensive experience with sterile in vitro laboratory tasks, including harvesting, storing, growing, and expanding neuronal cultures, formulating and adding compounds and molecular probes, measuring cell numbers with light microscopy and properties based on immunohistochemical markers, and writing SOPs and detailed records of all work.

Neurologist

The Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern Medical Center is accepting applications for a Board eligible/certified neurologist with an interest in cognitive and memory disorders. Research areas could include: 1) Running clinical trials; and 2) Studying clinical/pathological correlations of imaging and blood/CSF biomarkers. This faculty position will have a joint appointment in the Department of Neurology and Neurotherapeutics and the work will involve the interface of clinical and basic research.

Neurologist, Rehabilitation Service

As a neurologist on the Neurology and Rehabilitation Service at the Oklahoma City Veterans Affairs Health Care System,who subspecializes in rehabilitation. The duties of this position include: supervise residents and students and attend on the neurology inpatient service 2-3 months annually; attend on the rehabilitation inpatient service2-3 months annually; direct the power-mobility clinic; direct the spinal cord injury, spinal cord diseases, multiple sclerosis, and amyotrophic lateral sclerosis clinic; direct the stroke-care program. The applicant must be able toprovidecare and rehabilitation tothe following populations ofveterans: acute neurology patients in all outpatient and outpatient settings including intensive care units and emergency room; spinal cord injury, spinal cord disease, ALS and MS in the Hub and Spoke system of care; disabled patients due to neurological or orthopedic impairments for rehabilitation care on outpatient and inpatient settings. The applicant must be able to provide acute stroke and post-stroke care and supervise neurology stroke fellows who rotate at the VA. The applicant must participate in ongoing CARF accreditations activities for a Comprehensive Integrated Inpatient Rehabilitation Program, and assist in meeting standards forspecial accreditation in Stroke Rehabilitation. The applicant must be able to supervise neurology stroke fellows, neurology residents, other trainees and students who rotate on the Neurology Inpatient and Outpatient Service, and therefore must meet criteria for faculty appointment in Neurology at the University of Oklahoma Health Science Center.

Neuropathologist, Physician Scientist, Neurodegenerative Disease

The Department of Pathology at Northwestern University Feinberg School of Medicine seeks a full-time Assistant Professor, Associate Professor or Professor on the tenure track. Qualified candidates will be physician-scientists MD or MD, PhD, and be Board-certified in Neuropathology. They are expected to develop a federally funded, independent research program in the area of neurodegeneration and engage in collaborations with other researchers who study neurodegenerative diseases throughout Northwestern University.

PI, Medicinal Chemistry and Drug Discovery

SOUTHERN RESEARCH is seeking an outstanding scientist to join the faculty of the Chemistry Department in the Drug Discovery Division. We are particularly interested in attracting a scientist with an established research program with excellent translational potential toward the identification of novel therapeutic agents. Chemists with a strong desire to collaborate with biochemists, microbiologists, and our high-throughput screening center, especially in the areas of oncology, anti-infectives, or CNS and neurodegenerative diseases, are particularly encouraged to apply.

PhD Position – Motor Neuron Disease

An exciting opportunity has arisen for a PhD project in the field of neuroimaging in motor neuron disease (MND). MND is a devastating, fatal, incurable neurodegenerative condition that typically results in death within 2-3 years. Therapeutic efforts have been limited by an incomplete understanding of disease pathophysiology, and because an available biomarker is lacking with which to track therapeutic effects over short timescales; for this reason, many potential agents never make it to clinical trial. There is increasing evidence for abnormal energy metabolism in MND, both a hypermetabolic early phase characterised clinically by weight loss and, later, mitochondrial failure, which may contribute to motor neuronal cell death.

Physician Scientist, Tenure-Track

The Center for Translational Medicine (CTM) at the Lewis Katz School of Medicine at Temple University is seeking qualified candidates and candidate nominations for a Tenure Track Faculty Physician-Scientist dedicated to neurodegeneration research. This position will also have clinical responsibilities and a joint appointment in the Department of Neurology.

Physician, Neuropathologist

West Virginia University School of Medicine, Department of Pathology, Anatomy and Laboratory Medicine seeks an academically oriented, Board Certified/eligible Neuropathologist qualified for appointment at either the Assistant Professor, Associate Professor, or Professor rank with skills in surgical and autopsy neuropathology. Experience and ability to participate in other pathology specialty functions is desirable but not required. Pathologists with an academic focus in the neurosciences (eg, neurodegenerative disorders, tumor, stroke, etc) are encouraged to apply. Other service responsibilities and the effort levels designated in support of our academic and clinical service missions will be based on a candidate s training, skills and passions, as well as departmental and institutional needs. In addition to providing patient care, the successful candidate will be involved in the teaching of medical students and residents. For appointment at the Associate Professor or Professor rank, it is expected that candidates sustain an outstanding, extramurally supported research program.

Physician-Scientist (Faculty)

Lewis Katz School of Medicine at Temple University

Physician-Scientist, Tenure-Track

The Center for Translational Medicine (CTM) at the Lewis Katz School of Medicine at Temple University is seeking qualified candidates and candidate nominations for a Tenure Track Faculty Physician-Scientist dedicated to neurodegeneration research. This position will also have clinical responsibilities and a joint appointment in the Department of Neurology.

Post-Doctoral Fellow Research, RIC Sensory Motor Performance Program

General Summary: The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).

Postdoctoral Fellow

Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly qualified and motivated Postdoctoral Scientist to investigate the underlying disease biology of amyotrophic lateral sclerosis (ALS). The successful candidate will implement manifold in vitro and in vivo experimental approaches to help identify and validate innovative therapeutic targets for the treatment of ALS. These techniques include molecular biology, biochemistry, cell culture, immunoblotting, immunohistochemistry, microscopy, laser capture microdissection and the use of transgenic mouse models.

Postdoctoral Fellow

The international “Regulatory T cell responses at the crossroads of immune homeostasis and inflammation in the context of barrier diseases” (TregBar) project is an international research project funded by the Luxembourg National Research Fund`s (FNR) bilateral AFR funding instrument. The program will initiate long-term collaborations between the biomedical initiatives of the Luxembourg Institute of Health (Esch-sur-Alzette, Luxembourg) and the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg with the RIKEN Center for Integrative Medical Sciences (IMS) in Yokohama, Japan.

Postdoctoral Fellow

The lab for microRNA Models of Neurodegenerative Disease at the Institute of Molecular and Cell Biology is seeking to recruit a highly motivated Research Fellow to investigate pathogenic pathways underlying neurodegeneration linked to loss of microRNA function.

Postdoctoral Fellow

The successful candidate will participate in federal and private-funded projects aiming to understand the role and molecular mechanism of autophagy (an essential lysosomal degradation pathway) in the regulation of metabolism and animal behavior, using knockout, knockin and transgenic mice, cell biology, biochemistry, imaging and state-of-the-art behavioral techniques.

Postdoctoral Fellow, Boulis Lab

The Boulis laboratory in the department of Neurosurgery at Emory University in Atlanta, GA, is seeking a capable and self-motivated individual to oversee projects involving the transplantation of iPS cells for the treatment of motor neuron diseases and nerve damage.

Postdoctoral Fellow, Buchan Lab

A position is available in the Buchan lab to study cytoplasmic mRNA biology. We are particularly interested in the assembly, disassembly and function of stress granules and P-bodies, which are cytoplasmic mRNA-protein (mRNP) assemblies that are implicated in regulation of mRNA translation, storage and decay. Recent evidence also suggests important roles for these mRNP bodies in viral defense, cancer and neurodegenerative diseases. A related focus is on the role of vesicular trafficking pathways in mediating clearance of P-bodies, stress granules and aggregates of proteins implicated in neurodegenerative disease such as Amyotrophic Lateral Sclerosis (ALS).

Postdoctoral Fellow, Cai Lab

The Department of Cell Biology and Neuroscience at Rutgers University is currently accepting applications for a postdoctoral position to study (1) the cellular mechanisms regulating autophagy-lysosomal function; (2) how altered axonal transport impacts the autophagy-lysosomal system, leading to axonal degeneration; (3) how deficits in the endolysosomal pathway contribute to the dysregulation of neuronal signaling. Given that defective axonal transport has been implicated in the pathogenesis of major neurodegenerative diseases, our studies will yield fundamental information to advance our understanding of human neurodegenerative diseases. Candidates for this position should hold a PhD with a strong research background in neurobiology or cell biology, at least in one of these areas: membrane trafficking, organelle transport, mitochondrial quality control, neuronal signaling, and neurodegenerative mouse models. Interested individuals should send CV, a personal statement describing research interests, and names and details of 3 references to cai@biology.rutgers.edu. Att: Qian Cai, M.D., Ph.D. Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Nelson Biological Laboratories, Busch Campus, 604 Allison Road, Piscataway, NJ 08854. Lab Webpage: https://cbn.rutgers.edu/cb-profile/userprofile/qc29 Application review will begin immediately and will continue until a suitable candidate is selected.

Postdoctoral Fellow, Da Cruz Lab

The Da Cruz laboratory focuses on disease mechanisms and therapy development for human neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), the second most common dementia. The laboratory combines sophisticated mouse genetics, cutting-edge stem cell and genome editing approaches to model human neurological disorders in vitro.

Postdoctoral Fellow, De Paola Lab

A Postdoctoral Research Fellowship is available in the Laboratory of Synaptic plasticity and Repair of Imperial College London, starting immediately. The aim of this project is to gain new and fundamental insights into the cellular and molecular mechanisms that regulate the regeneration of adult neocortical circuits. We have previously demonstrated that certain populations of cortical neurons exhibit enhanced spontaneous regenerative capacity compared to others, and we are now interested in understanding the mechanisms responsible for this differential response to injury. Our goal is to develop effective strategies to enhance functional axon and synaptic regeneration (Holtmaat et al Nature protocols 2009; Canty et al Nature Communications 2013; Grillo et al Nature Neuroscience 2015).

Postdoctoral Fellow, Deleidi Lab

A position for a talented and highly motivated Postdoctoral Researcher is available within the scientific team “Mitochondria and Inflammation in Neurodegeneration” led by Michela Deleidi in Tübingen. The research focus of our group is on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in neurodegenerative diseases. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson’s disease. Our aim is to understand, at the molecular level, how immune responses within or outside the brain contribute to neurodegeneration. Our final goal is to translate fundamental discoveries to better preventive and therapeutic approaches for neurodegenerative diseases. Please see our website for more information about our research: https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/deleidi/research-areasfocus/.

Postdoctoral Fellow, Dupuis Lab

A 3-year post-doctoral position is available in Inserm U1118, Strasbourg, France under the supervision of Dr Luc DUPUIS.

Postdoctoral Fellow, Durham Lab

A postdoctoral position in ALS research is available in the laboratory of Dr. Heather Durham in the Rare Neurological Diseases Group at the Montreal Neurological Institute, McGill University, Montreal QC Canada. The project involves investigating the role of chromatin remodeling as a convergent mechanism in ALS and in neuronal stress responses (see https://www.ncbi.nlm.nih.gov/pubmed/28973294). The work would include investigation of epigenetic mechanisms in primary culture models, mouse models and post-mortem tissue as well as participation in a drug study in mouse and tissue culture models of ALS. This multidisciplinary project is funded by MDA and by an ALS Canada-Brain Canada Hudson Translational Team Grant involving collaborators with complementary expertise at other Canadian universities.

Postdoctoral Fellow, Farese-Walther Lab

We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.

Postdoctoral Fellow, Fitzpatrick Lab

The Fitzpatrick lab, a member of the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University in the City of New York (https://zuckermaninstitute.columbia.edu/), has openings for four postdoctoral scientists opportunities.

Postdoctoral Fellow, Fraenkel Lab

Are you an expert in neurodegeneration, with a passion for research that will have an impact on curing disease? We seek a talented post-doc to participate in an unprecedented study of the neurodegenerative disease ALS. Working with researchers at clinical and academic institutions across the United States, we are gathering data on approximately 1,000 ALS patients and controls. Induced pluripotent stem cell (iPSC) lines are being derived from each individual and these are being used to generate motor neurons for a wide range of omic studies. Our collaboration seeks to identify different subtypes of the disease, identify correlations between molecular pathways and clinical symptoms and propose therapeutic strategies.

Postdoctoral Fellow, Guo Lab

Postdoctoral positions are available in Dr. Junjie Guo’s lab in the Department of Neuroscience at Yale School of Medicine. The Guo lab studies questions at the intersection between RNA biology and neuroscience. Currently, we are interested in the roles of mRNA and noncoding RNA structures in neurodevelopment and neurodegenerative diseases, taking a combination of computational, biochemical, genetic, and genomic approaches. Our lab is situated within the dynamic and collaborative RNA biology and neuroscience communities at Yale that includes the Yale Center for RNA Science and Medicine, the Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR), and the Kavli Institute for Neuroscience at Yale.

Postdoctoral Fellow, Heutink Lab

A position for a post-doctoral researcher is available from 01.03.2018 within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink in Tübingen.

Postdoctoral Fellow, Hickman and Shuler Labs

This post doctoral research opportunity focuses combining microfabrication and cell culture to construct in vitro models of the human body or “Body-on-a-Chip” for use in drug development. Multiple organs and their physiological interactions are represented on a single device; these interactions are based on physiologically based pharmacokinetic models. Of particular interest will be to combine metabolically active tissue, such as from the liver, with electrically active tissues such as cardiac myocytes or neuronal cells and then conduct pharmacological studies in this system.

Postdoctoral Fellow, Hu Lab

A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply. Please visit http://hu.wicmb.cornell.edu/ for more details and send your CV and 3 letters of references.

Postdoctoral Fellow, Kalra Lab

Postdoctoral positions are available in the ALS Neuroimaging Research Unit at the University of Alberta. The mission of the lab is to further our understanding of the biology of amyotrophic lateral sclerosis (ALS) using advanced MRI methods. The lab is directed by Dr. Sanjay Kalra, a neurologist and researcher, and the director of the Canadian ALS Neuroimaging Consortium (CALSNIC).

Postdoctoral Fellow, Khurana Lab

One postdoctoral position is available in the Khurana laboratory (khuranalab.bwh.harvard.edu) at Harvard Medical School and Brigham and Women’s Hospital.

Postdoctoral Fellow, Knowles Lab

Applications are invited for a Postdoctoral Research Associate (PDRA) to work on the development and applications of a microfluidic platform for analysing of Fused in Sarcoma (FUS) protein assembly, with a focus on liquid-liquid phase transitions using recombinant protein, cellular and cultured neuron systems, a project funded by the Wellcome Trust. The PDRA will work in the group of Professor Knowles in the Department of Chemistry.

Postdoctoral Fellow, Meyer Lab

The Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital to move additional programs forward.

Postdoctoral Fellow, Mueller Lab

We seek a talented and motivated postdoc to join the laboratory of Dr Christian Mueller in the Horae Gene Therapy Center at the University of Massachusetts Medical School. Our dynamic and collaborative research environment at UMMS includes world renowned clinicians and scientists. Additionally, our location close to Boston supports many collaborations with academic and industrial research groups.

Postdoctoral Fellow, Neurobiology of Aging and Neurodegenerative Disease

The collaborative and interactive Arizona postdoctoral fellowship program in Neurobiology of Aging and Neurodegenerative Disease is seeking highly qualified applicants for positions supported by a National Institutes of Health training grant.  Institutions included in the research consortium include the University of Arizona, Arizona State University, Barrow Neurological Institute, The Translational Genomics Research Institute, Banner Alzheimer’s Institute, Banner Sun Health Research Institute, and Mayo Clinic.  All institutions are participants in the state wide Arizona Alzheimer’s Consortium.  Training programs afford the opportunity to study neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Amyotrophic Lateral Sclerosis, Traumatic Brain Injury, other related disorders, as well as non-pathological brain aging. Areas of interest include behavioral, systems and clinical neurosciences, molecular neurobiology and epigenetics, brain imaging, genomics, computational and statistical analysis of complex data sets, experimental therapeutics, and clinical neuropathological research.  Research resources include human longitudinal cohorts and data sets, a brain and body research donation program, PET and MRI research programs, wild type and transgenic rodent, non-human primate and human behavioral testing facilities, and cutting-edge cellular and molecular biological research methods with emphasis within each of the noted disciplines.  Trainees will benefit from a Professional Development Committee to foster career development from an omnibus perspective, and the training experience will be enriched via opportunities to work, learn, and produce across institutions, driven by a collaborative experimental training plan.  This is a U.S. Government funded training grant and is only available to U.S. citizens or Permanent Residents.  All institutions involved in this training program value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community.  Because, we seek a workforce with a wide range of perspectives and experiences, we encourage diverse candidates to apply, including people of color, women, veterans, and individuals with disabilities.

Postdoctoral Fellow, Neurogenetics

As postdoc you will be working on data from Project MinE (www.projectmine.com). This is unique genomic dataset in the field of Amyotrophic Lateral Sclerosis (ALS), a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles, which include epigenetic, whole genome sequencing and clinical data of several thousand of ALS patients and matched controls. We have recently published the first results of this dataset (Van Rheenen et al. Nat Genet. 2016 (PMID: 27455348), and Kenna et al. Nat. Genet. 2016 (PMID: 27455347)). Your focus will be on exploring adding external controls and cases to this dataset while preserving type I error in case-control comparisons, annotating the non-coding genome by integrating our data with other publicly available omics datalayers, including RNAseq, Hi-C and Chip-seq and relating this to case-control status. Another type of genomic variation potentially related to ALS we are interested in, is structural variation. This means you need to have experience in working with raw sequencing data on a large number of samples and be able to apply complex genetic statistics in this context. There is a suitable ICT setup available for you to achieve this. We expect you to be able to use various bioinformatic tools on next-generation sequencing data and combine these to identify possible novel ALS risk genes, and pathological pathways. Also, we would like you to integrate these genetic data with drug databases in order to prioritize potential new drug targets for ALS and repurposing of existing drugs for ALS. This part of the work will be done in collaboration with a biotech company. You will also be expected to participate in writing scientific papers and grant applications, provide methodological advice to other members of the team (bioinformaticians, PhD students, postdocs, technicians), and participate in educating bachelor and master students.

Postdoctoral Fellow, Pathology

This position is funded by ForeFront, an NHMRC Program grant, that brings together a multidisciplinary research team to address the diagnosis, management and treatment of frontotemporal dementia and related disorders. A junior postdoctoral researcher is required to contribute to projects exploring the pathogenesis of neurodegeneration with a particular focus on immune-mediated mechanisms. This is a valuable opportunity to expand your research skills.

Postdoctoral Fellow, Plowman Lab

The Department of Speech, Language, and Hearing Sciences at the University of Florida has a funded post-doctoral associate position available to work in the Swallowing Systems Core under the direct mentorship of Dr. Emily Plowman. This line is funded by an R01 grant from the National Institute of Neurological Disorders and Stroke (N.I.N.D.S) in the area of bulbar dysfunction in individuals with Amyotrophic Lateral Sclerosis. The successful post-doctoral associate would have the opportunity to work in the Swallowing Systems Core (SSC) that combines the expertise of both Dr. Plowman and Dr. Ianessa Humbert. The Swallowing Systems Core (SSC) is housed within the Dental Tower of Shands Hospital in the University of Florida Health Science Center and is equipped with its own research dedicated C-arm to perform high-resolution videofluoroscopy, fiberoptic endoscopic evaluation of swallowing workstation and high resolution manometry set up. The SSC currently comprises two Co-directors (Plowman and Humbert), two full time clinical coordinators, a biomedical engineer, four doctoral students, seven masters’ thesis students and five undergraduate honors students. The successful applicant would be expected to work cohesively with the entire SSC team.

Postdoctoral Fellow, Respiratory Physiology

Applications are being solicited for two NIH post-doctoral fellowships in respiratory neurobiology at the University of Wisconsin-Madison. The first position will investigate cellular mechanisms and physiological significance of neuroplasticity in the control of breathing, with an emphasis on sleep apnea. The second position will investigate functional outcomes of ex vivocell therapy (stem cell-based trophic factor delivery) to preserve respiratory motor neuron and diaphragm function in rodent models of Amyotrophic Lateral Sclerosis (ALS).

Postdoctoral Fellow, Sajjadi Lab

The Department of Neurology at the University of California, Irvine, invites applications for a post-doctoral fellow position in the laboratory of Dr. S. Ahmad Sajjadi MD, PhD beginning early 2017. The appointment is for 1 year with the possibility of extension upon satisfactory performance. We are seeking a highly motivated investigator with previous experience in neuropsychological assessments. Priority will be given to candidates with a recent PhD in neuroscience, psychology, or related fields and strong organizational and communication skills. The main purpose of this appointment is to establish a cohort of atypical dementia syndromes (mainly frontotemporal dementia) at the University of California, Irvine who will undergo regular clinical and neuropsychological assessments. Assessment of language and spontaneous speech will be a focus of the research and therefore, background in disorder of language will be desirable as is previous experience in neuro-imaging acquisition/analysis since the project will include structural MRI and PET scans. The position requires an individual who is an effective team player, highly organized, and innovative.

Postdoctoral Fellow, Sareen Lab

Dr, Dhruv Sareen’s independent research laboratory at the Cedars-Sinai Medical Center, Regenerative Medicine Institute focuses on using human iPSC technology to understand the molecular mechanisms underlying neurodevelopmental/degenerative diseases and how obesity is linked to the brain. His laboratory is particularly interested ‘disease-in-a-dish’ modeling for neuromuscular, neurodegenrative and motor neuron diseases including, amyotrophic lateral sclerosis (ALS). They are particularly interested in C9orF72 and other genetic forms of ALS and what are the common elements with sporadic forms of ALS. Using the iPSC platform his lab has developed novel methods for drug screening on patient motoneurons and dissecting mechanisms for motoneuron degeneration. In the context of stem cell modeling of neurodevelopmental (SMA) and neurodegenerative diseases (ALS) Dr. Sareen’s group is particularly interested in the mechanistic insights how specific neural cell types degenerate during the disease processes. They are using OMICS (proteome, transciptome, metabolome) and imaging methodologies to gain mechanistic insights into the mitochondrial and endorplasmic reticulum stress involvement. In addition, by understanding how the cells of the nervous system develop and differentiate we will be able to develop better and safer cells for transplantation and regenerative therapies. Dr. Sareen’s group has extensive experience in pluripotent and neural stem cell research. He has developed and directed a well-renowned human iPS cell core. He has published high-profile manuscripts on human iPSC-based disease modeling in SMA and ALS.

Postdoctoral Fellow, Sareen Lab

Dr. Dhruv Sareen’s independent research laboratory at the Cedars-Sinai Medical Center, Regenerative Medicine Institute focuses on using human iPSC technology to understand the molecular mechanisms underlying neurodevelopmental/degenerative diseases and how obesity is linked to the brain. His laboratory is particularly interested ‘disease-in-a-dish’ modeling for neuromuscular, neurodegenrative and motor neuron diseases including, amyotrophic lateral sclerosis (ALS). They are particularly interested in C9orF72 and other genetic forms of ALS and what are the common elements with sporadic forms of ALS. Using the iPSC platform his lab has developed novel methods for drug screening on patient motoneurons and dissecting mechanisms for motoneuron degeneration. In the context of stem cell modeling of neurodevelopmental (SMA) and neurodegenerative diseases (ALS) Dr. Sareen’s group is particularly interested in the mechanistic insights how specific neural cell types degenerate during the disease processes. They are using OMICS (proteome, transciptome, metabolome) and imaging methodologies to gain mechanistic insights into the mitochondrial and endorplasmic reticulum stress involvement. In addition, by understanding how the cells of the nervous system develop and differentiate we will be able to develop better and safer cells for transplantation and regenerative therapies. Dr. Sareen’s group has extensive experience in pluripotent and neural stem cell research. He has developed and directed a well-renowned human iPS cell core. He has published high-profile manuscripts on human iPSC-based disease modeling in SMA and ALS.

Postdoctoral Fellow, Shirley Ryan AbilityLab

The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).

Postdoctoral Fellow, Strittmatter Lab

Postdoctoral positions are available to study neural repair and/or neurodegeneration in Stephen Strittmatter’s laboratory.

Postdoctoral Fellow, Sun Lab

Postdoctoral opportunities are available in Dr. Shuying Sun’s laboratory at Johns Hopkins University School of Medicine. The lab will explore the fascinating frontiers of RNA metabolism dysfunction and RNA-targeting therapy in neurodegenerative diseases by combining molecular and cellular approaches, genome editing, proteomic, genomic and screening platforms.

Postdoctoral Fellow, Taylor Lab

A postdoctoral position to study the molecular and cellular mechanisms of neurodegenerative disease, including amyotrophic lateral sclerosis and frontotemporal dementia, is available at the St. Jude Children’s Research Hospital in Memphis, TN, USA. We identified that many of neurodegenerative diseases are caused by defects in the assembly, disassembly, or clearance of cellular packages of RNA and proteins known as RNA granules. Our research focus is to investigate the role of RNA granules in regulating gene activity, explore how granules are assembled and disassembled, and investigate how these types of defects in RNA metabolism can cause neurodegenerative diseases.

Postdoctoral Fellow, Van Damme Lab

The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains.

Postdoctoral Fellow, Vande Velde Lab

Dr. Christine Vande Velde is looking to recruit a PostDoc to her laboratory located at the CRCHUM facility, a research center affiliated with the Université de Montréal and located in Downtown Montreal.

Postdoctoral Fellow, Verfaillie Lab

The lab of Dr. Verfaillie at the Stem Cell Institute Leuven is looking for a postdoctoral fellow with expertise in: The lab of Dr. Verfaillie at the Stem Cell Institute at KU Leuven is recruiting an outstanding postdoctoral fellow highly versed in pluripotent stem cell biology techniques, including multicellular organoid cultures either in 2.5D and in 3D in suspension or in hydrogel based static or bioreactor cultures. The goal is to create lifelike small brain tissues, including the blood brain barrier or the cortex, that can be used as disease models in a dish, to study, Alzheimer’s, Parkinson, frontotemporal dementia or ALS available from teams at KU Leuven and the Flemish Institute of Technology (VIB), using patient iPSC and their isogenic counterparts. The technology should enable gaining superior insights in mature brain features such as defined connectivity and neuron-glia interactions, neurodegeneration phenotypes, and identification of druggable phenotypes.

Postdoctoral Fellow, Ward Lab

A postdoctoral position in cell biology and neurodegenerative diseases is available in the lab of Dr. Michael Ward, National Institute of Neurological Disorders and Stroke (NINDS), Neurogenetics Branch, in Bethesda MD. The Ward lab utilizes human iPSC-derived neurons to study basic mechanisms of neurodegeneration. By combining forward-genetics, proteomics, and molecular/biochemical techniques, we seek to identify converging disease pathways that underlie inherited neurodegenerative diseases. In parallel, we pursue complimentary drug discovery approaches using ultra high-content small molecule screens with colleagues in the National Center for Advancing Translational Sciences (NCATS).

Postdoctoral Fellow, Wolozin Lab

A NIH funded postdoctoral position is available in the laboratory of Benjamin Wolozin to study the role of RNA binding proteins, RNA metabolism and RNA granules in the pathophysiology of neurodegenerative diseases. The postdoctoral fellow will investigate how these processes are regulated, and how dysfunction contributes to disease. The studies will use phase separation biology, cell biology, imaging, optogenetics, proteomics, systems biology and RNAseq. The studies will take advantage of our finding that reducing the RNA binding protein TIA1 delays progression in a mouse model of tauopathy (Apicco, et al, Nature Neuro., 21(1):72-80, PMID: 29273772.)

Postdoctoral Fellow, Xia Lab

A research lab at the University of Central Florida Medical College invites you to apply for post-doctoral associate position. Research in the lab is focused on the genetic and molecular mechanisms of neurodegeneration in amyotrophic lateral sclerosis and Parkinson’s disease. Our team has published our findings in Acta Neuropath, EMBO J, the Journal of Clinical Investigation, PLoS Genetics, and PNAS. Post-doctors being recruited will help validate the pathogenic role of genetic mutations newly discovered in the lab using cell culture and animal models. The research lab is located at the UCF Burnett School of Biomedical Sciences at the Lake Nona campus. Researchers who have recently obtained their PhD degrees and seek to further develop their academic career are encouraged to apply for the positions. Please email your CV to Dr. Xugang Xia at xugang.xia@ucf.edu

Postdoctoral Fellow, Xu Lab

A postdoctoral position is available in Zuoshang Xu’s laboratory to study mechanism of motor neuron degeneration in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease.

Postdoctoral Fellow, Yang Lab

The Yang lab also studies pathogenic roles of astrocyte dysfunction in neurological diseases/disorders, such as fragile x syndrome (FXS) and amyotrophic lateral sclerosis (ALS). The lab employs novel genetically modified mouse tools, in combination with primary astrocyte and neuronal cultures, imaging, electrophysiological and biochemical/molecular techniques. The candidate must be able to handle rodents and are familiar with biochemical techniques and prior knowledge of neurodegenerative diseases is desirable. It is expected that the candidate should have a recent PhD (less than 2 years) in Neuroscience/Genetics/Cell Biology/Biochemistry or equivalent and is able to communicate well with others. To apply, please send your CV (via e-mail) including all past education and training, a brief description of research interests, list of publications and other scientific activities as well as names and e-mail addresses of three references to Dr. Yongjie Yang at: Yongjie.yang@tufts.edu.

Postdoctoral Fellow, Zhang Lab

Two fully funded postdoctoral positions are immediately available, in the laboratory of Chun-Li Zhang, Ph.D., Department of Molecular Biology. One is to examine human neurodegenerative disease by using human embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and age-matched directly reprogrammed neurons. The focus is on molecular and cellular mechanisms underlying degeneration and the identification of chemical compounds promoting neuronal survival and function.

Postdoctoral Position – Center fro Bionic Medicine

The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS). The PostDoc Fellow will be responsible for the design, execution and interpretation of experiments within a laboratory team environment and a larger laboratory research program of engineers, physical therapists and neuroscientists focused on sensory motor performance and rehabilitation within a major, nationally leading Academic Rehabilitation Hospital.

Postdoctoral Position – Fenghua Hu Lab

A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply.

Postdoctoral Position – Lewcock Lab

Joe Lewcock’s Lab at Denali Therapeutics is seeking to recruit Postdoctoral Scientists to interrogate the molecular and cellular pathways underlying neurodegenerative diseases, with the ultimate goal of identifying new drug targets. Candidates should have proficiency in a broad range of molecular genetic, biochemical, and cellular techniques including: molecular cloning, transfection, RNA interference, Western blotting, immunofluorescence and/or live imaging techniques, and quantitative image analysis.

Postdoctoral Positions – Institute for Genomic Medicine

Multiple postdoctoral positions in Precision Medicine in Columbia’s Institute for Genomic Medicine.

Principal Investigator, Laboratory of Neuronal Cell Biology

As Principal Investigator for the Laboratory of Neuronal Cell Biology (LNCB), he or she will be:

Principal Scientist, Neuroscience

We are seeking a Research Principal Scientist to join a vibrant and growing group currently focusing on developing new and effective therapeutics for neurodegenerative diseases, migraine and neuropathic pain. This position is within the Neuroscience Therapeutic Area, a key component of the Discovery Research unit at Amgen’s site in Cambridge, MA. The Principal Scientist will focus on in vivo model test systems and the development and validation of mechanism based pharmacodynamic measures supporting characterization and pipeline advancement of novel CNS therapeutics.

Principal Scientist, Neuroscience, In Vivo Pharmacology

The successful candidate will be a member of the West Point Pharmacology Department, a department that provides in vitro and in vivo pharmacology solutions to support a wide variety of neuroscience, infectious disease, and cardio-metabolic programs.

Research Assistant, Engle Lab

This is an Exciting opportunity at Boston Children’s Hospital to support a cutting edge developmental neuroscience laboratory using emerging techniques in single cell RNA sequencing (scRNAseq) to understand the molecular mechanisms of motor neuron diseases, including eye movement disorders and amyotrophic lateral sclerosis (ALS). (http://www.childrenshospital.org/research-and-innovation/research/labs/engle-laboratory).

Research Assistant, Jackrel Lab

The Jackrel Lab is interested in hiring a research specialist. We are looking for recent graduates in Chemistry, Biochemistry, Biophysics, Cell Biology, Genetics, Neuroscience, and related areas. Applicants with more senior experience will also be considered. Responsibilities will include driving an independent research project and assisting in the general organization and running of the lab. We study protein folding and misfolding, and how protein misfolding can lead to neurodegenerative disease. For more information about our research interests, please visit: https://sites.wustl.edu/jackrel/

Research Assistant, Neurodegenerative Disease

As a research assistant, the successful candidate will work with protein analysis (Western blot), histological analysis (immunofluorescence, in situ hybridization), analysis of data from in vivo neurotransmitter recordings (glutamate, dopamine recordings) and cytological analysis (immunofluorescence). The source of these samples will be from cell lines, animal models and human samples. The applicant will work close with patients and perform skin biopsies, blood sampling and lumbar punctures to obtain working material. The applicant will be responsible for analyzing these samples according to their respective protocols and the analyses are documented and stored in structured and easy to follow way.

Research Assistant, Spillantini Lab

Applications are invited for a Research Assistant role to work on a collaborative project between the groups of Professor David Klenerman and Professor Maria Grazia Spillantini to study the molecular basis of neurodegenerative disease.

Research Associate

Nuredis, Inc. discovers and develops small molecule therapies for a group of inherited neurodegenerative and neuromuscular diseases, aiming to treat the cause of disease rather than just managing symptoms. Nuredis was founded in 2016 based on technology licensed from Stanford, with facilities in Menlo Park. We are currently seeking self-driven, intelligent individuals to add their complementary talents to our highly-motivated team.

Research Associate

The position is for a full time Staff Research Associate to assist the PI in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus. The Staff Research Associate is expected to be open to learning new methods. One year of relevant laboratory experience including laboratory histology (embedding, cutting, immunohistochemistry, and coverslipping).The position represents an excellent opportunity to further basic laboratory and research skills in a dynamic clinical neuroscience environment. The successful individual will be an energetic, team player, self-directed learner with a keen interest in research.

Research Associate

Under the supervision of the Principal Investigator, the Staff Research Associate II (SRA II) will assist in the performance of behavioral testing and in the analysis of behavioral and neuroimaging data to support research on the neural bases of decision-making in healthy individuals with a family history of frontotemporal dementia. Specific techniques utilized in these studies will include online computer-based testing, task-based functional MRI, psychophysiology, voxel-based morphometry, functional connectivity, and computational modeling of behavior.

Research Associate – Taylor Lab

The Howard Hughes Medical Institute is seeking a highly motivated Research Specialist to join Dr. J. Paul Taylor’s group at St. Jude Children’s Research Hospital. The primary focus of this position will be the use of Drosophila melanogaster as a tool to investigate the molecular genetics of neurological diseases.

Research Associate II

Incumbent will assist with new metabolic targets to treat neurodegenerative disease. Under general supervision, assist the principal investigator and laboratory members in developing novel techniques and models to study the intersection between mitochondrial metabolism and neural physiology. Research duties will include assisting with animal handling, tissue harvest, dissections, and primary neural cell preparations. Additional responsibilities will include biochemical assays (immunoblot analysis ,subcellular fractionation), molecular biology (qRT-PCR and genetic manipulation of cells with siRNA, viral vectors, or CRISPR technology), and specialized metabolic assays (Seahorse XF analysis, plate-based enzymatic assays). Preparation of samples for high-content imaging or mass spectrometry analysis will also be required. Further duties will include general lab maintenance responsibilities, such as organization and management of supplies, chemical reagents, and animals.

Research Associate II/III

Summary

Research Associate, Baloh Lab

Under the direction of the PI or research staff, the Research Associate will help us achieve our research goals by performing and managing tissue culture projects in the lab. The primary focus will be human fibroblasts and stem cell culture, but primary neuron culture from animal models will also be performed.

Research Associate, Fraenkel Lab

The research group of Professor Ernest Fraenkel seeks a talented scientist to participate in an unprecedented study of the neurodegenerative disease ALS. Working with researchers at clinical and academic institutions across the United States, we are gathering data on approximately 1,000 ALS patients and controls. Induced pluripotent stem cell (iPSC) lines are being derived from each individual and these are being used to generate motor neurons for a wide range of omic studies. Our collaboration seeks to identify different subtypes of the disease, identify correlations between molecular pathways and clinical symptoms, and propose therapeutic strategies.

Research Associate, Gao Lab

A Research Associate position in the laboratory of Dr. Fen-Biao Gao at the Department of Neurology is available to help study frontotemporal dementia using induced pluripotent stem cells (iPSCs). Candidates with substantial research experiences in molecular biology (such as western blot, cloning etc.) and cell biology (such as stem cell culture and differentiation, or mammalian cell cultures in general) are encouraged to apply. Candidates with PhD or MD degrees will be considered as well.

Research Associate, Grinberg Lab

The Staff Research Associate II (SRA II) position is for a full time lab technician (Research Assistant) to assist the Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus (see http://grinberglab.ucsf.edu).

Research Associate, Meyer Lab

They Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital. Our laboratory is looking for a highly motivated, Research Associate with minimum 2 years of experience to join our young and energetic team. The position does not require a background in gene therapy, but experience in performance of ELISAs and ELISpots, or previous experience working in a clinical laboratory, would be of advantage. The candidate will perform research experiments using patient samples, document and maintain exact records of experiments, prepare laboratory reports and assist with analyzing data.

Research Associate, Neuro-Muscular Group

We are seeking a Research Associate to join the Neuro-Muscular group at CRISPR Therapeutics, an exciting, fast growing and well-financed company. The successful candidate will be an integral part of a team whose aim is to discover the next generation of genetic therapies for serious neurodegenerative diseases. The position requires enthusiasm, passion, attention to detail and a desire to create new medicines for patients.

Research Associate, Neuroimaging

One Research Associate position is currently available at the Laboratory of Neuro Imaging in the area of neuroimaging genetics, involving the development of algorithms for the identification of novel multimodal (imaging and genetic) feature combinations and models that explain such imaging-genetic interactions and facilitate diagnoses and prognoses in neuropsychiatric, neurodegenerative, and neurodevelopmental brain disorders. Additional responsibilities will be to train student researchers and interact with other laboratory assistants on common projects. Other key responsibilities will be documentation of procedures using word processing, data base and web-based applications, and supervised statistical analyses, figure and table preparation for various manuscripts and scientific presentations. The successful candidate will have a strong background in multimodal brain image analysis, large-scale genetic association study and statistical modeling. Knowledge of neuroanatomy and basic neuroscience, computer programming experience (working knowledge of Linux, Matlab, R, Python, C/C++, etc.) and excellent communication and writing skills are desired. Experience on database, bioinformatics, graphical models, dimensionality reduction, and machine learning is desirable.

Research Associate, Process Analytics

Voyager Therapeutics is a gene therapy company developing life-changing treatments for severe neurological diseases. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector optimization and engineering, dosing techniques, as well as process development and production. The company’s pipeline is focused on severe neurological diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease, spinal muscular atrophy (SMA), frontotemporal dementia and Alzheimer’s disease and severe chronic pain.

Research Associate, Proteomics

Job description

Research Associate, Svendsen Lab

The Svendsen Laboratory at the Cedars-Sinai Regenerative Medicine Institute is looking 1hr personnel to join our dynamic group. The incumbent should have an interest in the basic science of stem cells and neuroscience. By understanding how the cells grow and differentiate we will be able to produce a better cell for transplantation and develop techniques for disease modeling. The laboratory technician will, under the direction of the P1, lab manager and project scientist, assist in the conduct of research in Amyotrophic Lateral Sclerosis (ALS).

Research Associate, Thomsen Lab

Dr. Gretchen Thomsen’s Laboratory at the Cedars-Sinai Regenerative Medicine Institute is looking for personnel to join our dynamic group. The incumbent should have an interest in the basic science of stem cells and animal research. The laboratory technician will, under the direction of the PI and lab manager, assist in the conduct of research in amyotrophic lateral sclerosis (ALS) and traumatic brain injury (TBI).

Research Associate, ViTAL Consortium

The postholder will join the ViTAL consortium of researchers working on Amyotrophic Lateral Sclerosis (ALS), funded by the charity TARGET-ALS. They will identify toxic elements that are secreted through exosomes in ALS, and determine their role in ALS. (Fixed-term until 30 June 2018)

Research Lead, CNS

The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for:

Research Scientist

AC Immune is seeking a highly qualified Research Scientist to expand the

Research Scientist

Inscopix is looking for a talented neuroscientist with a strong background working with rodent models of neurodegenerative disease who is interested in pursuing groundbreaking brain science in a highly-motivating and fast-paced entrepreneurial environment. You will have unique opportunities to work in close collaboration with an interdisciplinary team of driven neuroscientists, physicists, engineers, and data scientists. If you are looking for an opportunity that immerses you in 21st century neuroscience, we want to hear from you!

Research Scientist

The Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco (UCSF) is seeking a molecular/cell biologist to design, develop and validate novel tools for the study of neurodegenerative diseases. The director of the IND is Nobel Laureate Dr. Stanley Prusiner.

Research Scientist

The researcher will be devoted to the development of advanced techniques of in vivo Clinical Biochemistry, in particular metabolic (MR spectroscopy), microstructural and molecular (diffusion tensor imaging) and functional (fMRI) imaging, for the study of the central nervous system and neuromuscular system. The research activity will be applied to inflammatory, neurometabolic, neurodegenerative and neoplastic disorders, aimed to a) the identification of early diagnostic and prognostic markers and surrogate markers of treatment; b) the characterization of brain activations patterns; c) optimization of structural and functional connectivity analysis.

Research Scientist

This scientist will lead an early-stage, hit-to-lead drug development project for Amyotrophic Lateral Sclerosis (ALS). Initially, he or she will conduct in-house experiments and work with external collaborators and CROs to establish a structure-activity relationship and guide the associated medicinal chemistry work. This individual will advance the project into the lead optimization phase, including ADME and in vivo efficacy. The requirements include a PhD in the biomedical sciences, competency in mammalian cell culture and assay development, background in neuroscience research, and industry experience in CNS drug development. Salary will be commensurate with experience; BrainXell offers full health and dental benefits.

Research Scientist

Under general direction of the Principal Investigator (PI), leadership investigators, and project manager, the incumbent will undertake project activities under a CIRM award developing an embryonic stem cell-based therapy to treat Amyotrophic Lateral Sclerosis (ALS), making innovative and significant independent contributions pertaining to achievement of project milestones.

Research Scientist

We are currently seeking a highly motivated, experienced scientist to join the stem cell group in the Neuroscience department to aid in target discovery and validation in the areas of psychiatry and neurodegeneration.

Research Scientist

We are looking for an experienced BS or MS degreed research scientist to join the Neuroscience department. The candidate will play a hands-on role in a highly collaborative team responsible for research on neurodegenerative diseases. You will conceive, conduct, and analyze experiments to identify and evaluate compounds or biologics in various assays and cellular models. These include but are not limited to bioanalytical and biochemical assays, human ES/iPS derived neuronal models, and analysis of tissue samples.

Research Scientist

We are looking for an experienced research scientist to join the Neuroscience department. The scientist will assume a hands-on role in a team responsible for an early drug discovery project for a neurodegenerative disorder. The scientist will conceive, conduct, and analyze experiments to identify and validate novel targets and low molecular weight modulators. In vitro and ex vivo models, including hPSC-derived neuronal platforms, and other molecular and cell biology techniques, will be heavily utilized within projects. Excellent communication and teamwork will be critical.

Research Scientist

We are seeking highly motivated individuals with BS/MS degrees to join a dynamic research group in the Neurosciences Division at Novartis Institutes for Biomedical Research in Cambridge, MA. The individual will conduct hands-on research directed towards understanding the molecular mechanisms underlying neurodegenerative disorders, and identify and evaluate small molecule compounds or biologics that target key pathogenic events in these diseases. Proficiency in the use of current molecular biology and biochemical techniques is expected. Extensive experience in mammalian cell culture, viral transduction techniques as well as gene knockdown technology and stable cell line generation are preferred. Candidates should have strong data analysis and communication skills. In addition to the above expertise candidates are expected to gain new skills based on evolving project needs and demands.

Research Scientist in Autoradiography

AC Immune is seeking a highly qualified Research Scientist. The candidate must possess scientific background in structural biophysics and protein dynamics in neurodegenerative diseases and a clear record of accomplishment in an academic or a commercial setting. S/he will work on the discovery and characterization of PET radiotracers for the diagnosis of neurodegenerative disorders. Previous experience in neuroscience and neurodegenerative disorders, notably ALS and FTD along with TDP-43, is an advantage. S/he must have demonstrated their ability to make significant discoveries in an academic setting or bring a research product to a clinical stage.

Research Scientist, ALS

Under general direction of the Principal Investigator (PI), leadership investigators, and project manager, the incumbent will undertake project activities under a CIRM award developing an embryonic stem cell-based therapy to treat Amyotrophic Lateral Sclerosis (ALS), making innovative and significant independent contributions pertaining to achievement of project milestones.

Research Scientist, Neuroinflammation

The Krembil Research Institute at the University Health Network in Toronto Canada is seeking an early to mid career basic scientist in the area of neuroinflammation. Preference will be given to individuals with a research focus on the involvement of innate immunity, including the roles of immune mediators such as microglia and astrocytes, and their expressed cytokines and chemokines, in neurodegenerative diseases affecting the human CNS. The successful candidate will have a PhD or MD/PhD, postdoctoral experience and demonstrated research excellence. The successful candidate will be expected to qualify for an appointment at the Assistant or Associate Professor level (status only) in the appropriate department at the University of Toronto.

Research Scientist, Pathology

The Department of Pathology currently has an outstanding opportunity for a Research Scientist/Engineer 2. Under the general direction of the PI, this position provides comprehensive research to develop biomarkers for the diagnosis and staging of neurodegenerative diseases, and for the evaluation of potential disease modifying agents.

Research Scientist, Protein Sciences

We are seeking a Scientist with expertise in protein expression, purification and analytical characterization to contribute to our drug discovery efforts.

Research Scientist, Senior Research Scientist, Biomarkers

Denali Therapeutics is seeking to recruit a Research Scientist/Senior Research Scientist in support of the company’s growing translational biology and biomarker needs. This individual will work in close collaboration with colleagues in the In Vivo group, Research, Development Sciences, and Clinical Development to implement biomarker assays in support of preclinical target engagement studies. S/He would also contribute towards discovery/development of novel biomarkers for target engagement assessment and disease biology.

Research Specialist

A full-time position is available in the laboratory of Dr. Corey McMillan in the Department of Neurology at the University of Pennsylvania. This laboratory focuses on translational neuroscience questions related to improving the diagnostic and prognostic biomarkers of related neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). We also explore genotype and phenotype relationships using a multimodal approach that integrates clinical, imaging, genetic, and biofluid datasets. Applicant responsibilities will include collection of psychometric and imaging data from patients with ALS and/or FTD, preliminary statistical analyses, database management, processing biofluid samples, and administrative coordination with consortia collaborators.

Research Specialist – Taylor Lab

The Howard Hughes Medical Institute is seeking a highly motivated Research Specialist to join Dr. J. Paul Taylor’s group at St. Jude Children’s Research Hospital. The primary focus of this position will be the use of Drosophila melanogaster as a tool to investigate the molecular genetics of neurological diseases.

Research Specialist, Grossman Lab

A full-time position is available in the laboratory of Dr. Murray Grossman in the Department of Neurology at the University of Pennsylvania. This lab focuses on cognitive neuroscience and clinical questions relating to language, memory, and neurodegenerative disease (e.g., primary progressive aphasia, behavioral variant frontotemporal degeneration, Alzheimer’s). Applicant responsibilities will include the collection and analysis of PET scan data, and the collection and analysis of structural MRI data. This position will provide a strong foundation for individuals interested in continuing their education in graduate or medical school.

Research Specialist, Plotkin Lab

A full-time position is available in the lab of Alice Chen-Plotkin in the Department of Neurology at the University of Pennsylvania. Our lab researches neurodegenerative disease, with a particular focus on frontotemporal dementia and Parkinson’s disease. Projects range from studying the basic mechanisms of disease to finding and developing clinically useful tools such as biomarkers. Responsibilities for this position will include assistance with biochemical, molecular biological, and cell biological assays as needed to meet scientific goals. In addition, familiarity with analysis of large genetic datasets is preferred, including knowledge of statistical and computational methods (i.e. familiarity with linear/logistic regression, ability to use R or other statistical tools). All members of the lab are also expected to attend weekly lab meetings and to participate in the educational activities (e.g. journal club) of the lab.

Research Specialist, Southworth Lab

The Institute for Neurodegenerative Diseases (IND) at UCSF, Mission Bay Campus is seeking a Specialist for full-time work to perform and manage research activities in biochemistry and structural biology. The position is in the laboratory of Dr. Daniel Southworth and will support research efforts using cryo-electron microscopy to determine 3D structures of important biological macromolecules associated with human neurodegenerative diseases. Highly motivated candidates capable of independent problem solving and teamwork are encouraged to apply. This position will be part of a collaborative environment with access to state-of-the-art facilities in the Sandler Neurosciences Building on the UCSF Mission Bay campus. A successful candidate will be hired at the Junior, Assistant, or Associate Specialist rank commensurate with experience and qualifications.

Research Study Coordinator

The Division of Neuromuscular Disorders is seeking a Research Support Coordinator to join a very active clinical research program with multiple ongoing research studies. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). The research support coordinator will work closely with clinical research coordinators, data manager, statistician, clinical staff and the Principal Investigator.

Research Technician

The laboratory is seeking a motivated individual to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under the direction of the Principal Investigator, the research technician will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining and preparation of libraries for high throughput sequencing. The incumbent will also be responsible for handling patient samples and genetic testing of neurodegenerative conditions as part of a research project in collaboration with the ALS multidisciplinary clinic. Additional skills include maintenance of cell cultures, ordering necessary reagents to conduct experiments, and participation in joint upkeep of the lab. Experience in mouse handling and surgical procedures is preferred. The candidate will participate to the research activity of the lab and is expected to be fully engaged in the scientific projects, as well as participate to the scientific lab meetings. The individual must pay attention to details, can work independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team.

Research Technician

We are looking for individuals interested in a career in medicine to join our productive clinical research team for a 1-year term limited position (possible extension 1-3 years depending on funding).

Research Technician, Biffi Lab

Our lab aims at developing and testing a novel pharmacological platform, based on MRI/PET traceable nanoparticles targeted to activated microglia, as a therapeutic approach to track and modulate neuroinflammation in Amyotrophic Lateral Sclerosis. This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.

Research Technician, Maniatis Lab

The Maniatis lab iat CUMC is seeking a highly motivated Technician B to work on a project focusing on the role of innate immunity and autophagy pathways on the progression of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). The technician will work closely with colleagues using techniques such as gene expression profiling, in vitro cell culture assays, and in vivo mouse genetics.

Research Technician, Morrison and Rothstein Labs

A Research Technologist to work in the laboratories of Drs. Brett Morrison and Jeffrey Rothstein in the Department of Neurology. Our laboratories study the pathogenesis of the devastating motor neuron disease, amyotrophic lateral sclerosis (ALS; commonly referred to as Lou Gehrig’s disease). A particular focus is on the role played by oligodendrocytes, a key support cell in the brain that is dysfunctional and degenerates in ALS.

Scientific Director, Research Professor

VIB and UAntwerp are in search for a dynamic, internationally recognized leader in genetics and genomics to inspire and lead the VIB research centre at the University of Antwerp. The selected candidate will be appointed as scientific director at VIB and will have a research professor appointment (ZAPBOF) as (full) professor at the University of Antwerp.

Scientist

As Scientist and critical member of the committed Neuro-Immunology team, you’ll help Alector discover and develop novel drugs targeting dementia and other neurological disorders. You will design and prioritize your own experiments and research endeavors to further Alector’s collective scientific understanding. In doing so you’ll apply your scientific insights to grow the company and guide its direction. Your work will be both inside and outside of the lab, and both strategic and hands-on. As an early hire, you’ll be influential in championing and developing Alector’s culture.

Scientist – Neuroscience FDE

Lilly Neuroscience is seeking an associate-level scientist (Bachelors or Masters) to join the Neurodegeneration Team to facilitate its mission of discovering novel medicines for the treatment of Alzheimer’s disease, Parkinson’s disease, and other related neurodegenerative conditions. The individual must possess a keen interest to understand the pathophysiological processes that underlie neurodegenerative conditions such as Alzheimer disease and have an exceptional attention to scientific detail.

Scientist I, ALS

Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention. The successful candidate will execute in vivo experiments to support the validation of novel drug targets and the development of small- and large-molecule drugs for the treatment of ALS. A major component of this work will be the assessment of drug candidates in a multiple rodent models, using a wide variety of morphological and functional endpoints, working closely with members of the ALS team as well as multiple internal and external collaborators. You will work in a fast paced, highly collaborative team environment at an exciting period for ALS research.

Scientist I, ALS

Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention. The successful candidate will execute in vivo experiments to support the validation of novel drug targets and the development of small- and large-molecule drugs for the treatment of ALS. A major component of this work will be the assessment of drug candidates in a multiple rodent models, using a wide variety of morphological and functional endpoints, working closely with members of the ALS team as well as multiple internal and external collaborators. You will work in a fast paced, highly collaborative team environment at an exciting period for ALS research.

Scientist I, Analytical Development (Small Molecule + ASO)

The individual will develop, implement, and qualify innovative analytical solutions for the characterization and testing of ASOs and pharmaceuticals (both off-line and on-line). This work will support process and formulation development and will drive the control strategy. Key areas of focus will be in enhanced impurity monitoring, simple and specific identity testing, and evaluating novel formulations. The primary methods are HPLC/UPLC, MS, and spectroscopy, but the use of other methods is required and should be explored.

Scientist I, Biomarkers

The Discovery and Early Development Biomarkers group, part of Biogen’s Research and Early Development department is seeking a highly motivated scientist to join a dynamic team engaged in the discovery and progression of novel biomarkers for neurodegenerative diseases.

Scientist I, Neuro Discovery, Research

We seek an independent neuroscientist focused on identification of new targets for promoting axon regeneration, axon integrity and synapsis. The candidate will (1) be expected with the goal of delivering new targets to the clinic, focusing on multiple sclerosis and other neurodegenerative diseases, (2) apply in vitro and in vivo models to study the underlying mechanisms of degeneration and dysfunction in neurodegenerative diseases, (3) be familiar with cellular and animal models to study the effects of small molecules, antisense oligonucleotides, and antibodies for their roles in regeneration and repair, (4) enjoy membership amongst a highly productive and dynamic research team with many possibilities to collaborate internally and with external academic leaders, and (5) be expected to lead the project, present and publish their findings.

Scientist I, Research

Perform Drosophila neurobiological research to study neuronal function including electrophysiology and imaging. Design and execute experiments that test disease biology and investigate neuronal function in genetic models of neurodegenerative disease in the fly. Conduct hands-on research and interact with other members of the Department of Neurology Research engaged in biomedical and behavioral studies. Perform research involving electrophysiological and imaging techniques in Drosophila.

Scientist I/II

Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention.

Scientist I/II, NeuroImmunology

The Biogen Department of NeuroImmunology seeks a highly motivated and keen experimentalist whose primary responsibility is to advance drug discovery and development by performing bench research. The individual will be expected to design studies and execute research aimed at target discovery as well as the development of therapeutic approaches to treat acute neurological indications and chronic neurodegenerative diseases. The individual is expected to function independently and creatively within the context of project teams, drawing on pertinent literature, and to foster collaborations to maximize synergies and cross disciplinary approaches to advance the studies. The work will involve a wide array of in vitro and in vivo techniques and is expected to yield high quality publications.

Scientist I/II, Research

The Biogen Epigenetics group seeks a highly motivated, creative scientist who will expand capabilities in epigenomic engineering within our Epigenetics and Cell & Gene Therapy groups, in consultation with colleagues in Neurology and Rare Disease groups. This scientist will have interests in the discovery and validation of mechanisms, pathways and potential drug targets for the treatment of neurodegenerative and rare diseases. S/he will create the means for the validation and modulation of targets of interest through the development of epigenomic engineering approaches for the modulation of disease-relevant target genes.