Figure 1. Micrographs of spinal cord motoneurons showing SOD1-immunoreactive inclusions.
Image credit: Forsberg, et. al. 2010 under CC BY license

Job Opportunities

To submit any new job opportunities for this list, please email alsresearchforum@prize4life.org. List the employer, location, closing date if applicable, and a link to more information. Jobs are removed after 3 months, unless requested otherwise.

This free job bulletin board aims to help scientists identify job opportunities in the field of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Positions described as broadly spanning neurodegenerative diseases (NDG) are noted as ‘NDG‘. The job listing includes research positions at all levels, as well as non-research positions for which a research background at the MS, PhD, or MD level is required.


Click the title of any table column to sort.

Academia

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
NEW! Postdoctoral Fellow: Kiskinis Lab (iPSC/ALS disease modeling)

Postdoctoral Fellow: Kiskinis Lab (iPSC/ALS disease modeling)

(Click title to open job details in a new window.)
Description:

We are looking for outstanding candidates to join the Lab of Stem Cell Biology and Neurodegeneration lead by Dr. Evangelos Kiskinis at the Feinberg School of Medicine, Department of Neurology at Northwestern University in Chicago, IL. Positions are available at the Postdoctoral Level.


The broad objective of our lab is to understand the nature of the degenerative processes that drive ALS. We pursue this objective primarily by creating in vitro models of disease that enable us to screen and identify relevant therapeutics. We utilize patient-specific induced pluripotent stem cells (iPSCs) and direct reprogramming methods to generate different neuronal subtypes of the human CNS including spinal cord motor neurons . We then study these cells by a combination of genomic and proteomic approaches as well as functional electrophysiological assays.


Applicants should have a PhD or equivalent doctoral degree with at least 3 years of proven research experience as well as at least one first author publication. Expertise in any of the following approaches: iPSC technologies, protein folding, CRISPR-Cas9 gene editing, ChIP, RNA-Seq, molecular biology, electrophysiology, optogenetics, MATALAB programming and stem cell biology are highly favorable.


Feinberg Medical School is superbly located in the downtown Chicago area, a few minutes away from Lake Michigan as well as the Shopping and Restaurants of the Magnificent Mile. Salaries are highly competitive. Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women and minorities are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.


Please email Dr. Kiskinis with a copy of your CV and a letter of recommendation at:

evangelos.kiskinis@northwestern.edu


For more information on our lab please visit:

http://labs.feinberg.northwestern.edu/kiskinis/


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Link: http://www.nature.com/naturejobs/science/jobs/598607-ipsc-neurological-disease-modeling
Employer: Northwestern University
Principal investigator: Evangelos Kiskinis
Location: Chicago, IL
Sector: Academia
Degree required: PhD, MD, PhD/MD
Conditions: ALS
Job posted: December 5th, 2016
Northwestern UniversityChicago, ILPhD, MD, PhD/MDALSDec 05, 2016
Assistant Professor, Neuroinflammation Research

Assistant Professor, Neuroinflammation Research

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Description:

The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to study neuroinflammation and complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/).


Qualified applicants holding Ph.D., M.D. or equivalent degrees will be considered for appointment at assistant, associate or full professor levels. The successful candidate will be expected to use interdisciplinary approaches to direct an extramurally-funded research program in inflammatory related research associated with neurologic disorders. Institutional strategic interests for this position include Alzheimer’s disease, Multiple Sclerosis, Parkinson’s disease, amyotrophic lateral sclerosis, and brain injury. Qualified applicants in other areas of translational neuroscience research also will be considered. The successful candidate is expected to synergize/collaborate with existing research and clinical faculty, will have access to core facilities and clinical samples, and may leverage opportunities to collaborate with investigators at affiliate institutes including Phoenix Children’s Hospital, the Translational Genomics Research Institute, and the University of Arizona.


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Link: https://goo.gl/cuO6N3
Employer: Barrow Neurological Institute
Location: Phoenix, AZ
Sector: Academia
Degree required: PhD, MD, MD/PhD
Conditions: ALS, NDG
Job posted: November 17th, 2016
Barrow Neurological InstitutePhoenix, AZPhD, MD, MD/PhDALS, NDGNov 17, 2016
Postdoctoral Fellow, UCF

Postdoctoral Fellow, UCF

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Description:

A group of established investigators recently join the University of Central Florida (UCF) Medical College to form a competitive research team studying the mechanisms of neurodegeneration in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). The team uses genetically engineered rats as a relevant model for the in vivo study of neurodegeneration associated with genetic mutations discovered by the team and by the other groups. Team members have documented findings in the journals including PLoS Genetics (2010 and 2011), the Journal of Clinical Investigation (2012), EMBO J (2013), PNAS (2013), and Acta Neuropath (2015). The team is funded by multiple NIH grants and has received supports from the UCF. The team invites experienced persons to join as a key member in the journey of discovery on disease mechanisms and therapies.


Post-doctors: Post-doctor positions are immediately available to candidates who have experienced one or more of the following research activities: 1) characterizing transgenic or knockout mouse or rat models for neurological diseases; 2) characterizing protein-protein interaction with biochemical and molecular approaches; 3) studying synaptic function with molecular and physiological approaches; and 4) studying autophagy or proteasome dysfunction in disease conditions. Publication in a related field is required.


Technicians: An animal technician position is available to applicants who have received training on breeding transgenic or knockout mice or rats, extracting DNA from mouse or rat tails, genotyping rodents by PCR, and perfusing rodents for histology. Another technician position is available to applicants who have received adequate training on pronuclear injection to create mutant mice or rats. This position requires experience in harvesting fertilized rodent eggs, injecting fertilized rodent eggs, and transplanting injected eggs into the uterus of pseudo-pregnant female animals.


Lab manager or senior scientist: A position is available to interested person who has experience in training students and is good at scientific writing. Retired researcher who wants to move to Florida is also considered.


The University of Central Florida is located in Orlando of the sunny state Florida. The medical school is quite new and is rapidly growing. Interested persons are sincerely invited to apply for the positions. Please send cover-letter and CV to Dr. Grace H. Zhou or Dr. Xugang Xia at grace06zhou@yahoo.com, or, xia67gang@yahoo.com


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Link: http://www.nature.com/naturejobs/science/jobs/596715-post-doctor-and-technician
Employer: University of Central Florida
Location: Orlando, FL
Sector: Academia
Degree required: PhD, MD, MD/PhD
Conditions: ALS, NDG
Job posted: November 17th, 2016
University of Central FloridaOrlando, FLPhD, MD, MD/PhDALS, NDGNov 17, 2016
Postdoctoral Position – Fenghua Hu Lab

Postdoctoral Position – Fenghua Hu Lab

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Description:

A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply.


Please visit http://hu.wicmb.cornell.edu/ for more details and send your CV and 3 letters of references.


 


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Employer: Cornell University
Principal investigator: Fengua Hu
Location: Ithaca, NY
Sector: Academia
Degree required: PhD, MD, PhD/MD
Conditions: ALS, FTD
Job posted: October 27th, 2016
Cornell UniversityIthaca, NYPhD, MD, PhD/MDALS, FTDOct 27, 2016
PhD Student for Drosophila Research – ALS and CMT

PhD Student for Drosophila Research – ALS and CMT

(Click title to open job details in a new window.)
Description:

The Max-Planck-Institute for Molecular Biomedicine has an opening for a PhD Student (position-code 23-2016) in the Molecular Neurogenetics Laboratory (group leader: Erik Storkebaum). We combine Drosophila and mouse genetics to study the molecular pathogenesis of the neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and Charcot-Marie-Tooth peripheral neuropathy (CMT). The project that is offered will focus on the molecular mechanisms underlying CMT associated with mutations in tRNA synthetases, and is based on our recent publications in this field. It involves the generation and characterization of novel Drosophila CMT models, which will complement our existing models. Drosophila genetic approaches in combination with in vivo studies of protein synthesis will subsequently be used to evaluate whether all disease causing mutations in tRNA synthetases cause peripheral neuropathy phenotypes through a gain-of-toxic-function mechanism leading to inhibition of translation, or alternatively, whether different mutations lead to peripheral neuropathy through disparate mechanisms.

A broad spectrum of methods will be applied, all of which are well established in our lab, including Drosophila genetics, the recently developed FUNCAT technique, immunohistochemistry, several imaging techniques, molecular biology, protein biochemistry, and possibly also mouse genetics.


For further information please visit the Storkebaum lab website:

http://www.mpi-muenster.mpg.de/22108/storkebaum


We are looking for a highly motivated and team-oriented PhD student interested in a scientific career and with a backgound in biomedical sciences (biology, bioengineering, biochemistry, medicine, etc). Previous experience with Drosophila or mouse genetics is a plus but not required. A good command of the English language is necessary.

Applications are invited till November 15, 2016, starting date will be January 2017 or later.

We offer the challenging, dynamic, international and multidisciplinary environment of the Max Planck Institute, with state of the art facilities for mouse and Drosophila genetics, histology, light and electron microscopy, next-generation sequencing, cell sorting and proteomics. For people without German language skills, help with German administration, apartment hunting, etc. will be provided. The salary and working conditions will be according to the regulations of the Max Planck Society.


The Max-Planck society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply. Please send your application (with the position-code 23-2016), including motivation letter (up to one page), CV and the names of 2 referees via email to:

career@mpi-muenster.mpg.de


Max Planck Institute for Molecular Biomedicine

Roentgenstrasse 20

48149 Muenster

Germany


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Employer: Max-Planck-Institute for Molecular Biomedicine
Location: Muenster, Germany
Sector: Academia
Degree required: MSc
Conditions: ALS
Job posted: October 25th, 2016
Applications close: November 15th, 2016
Max-Planck-Institute for Molecular BiomedicineMuenster, GermanyMScALSOct 25, 2016
Post-Doctoral Fellow Research, RIC Sensory Motor Performance Program

Post-Doctoral Fellow Research, RIC Sensory Motor Performance Program

(Click title to open job details in a new window.)
Description:

General Summary: The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).


The PostDoc Fellow will be responsible for the design, execution and interpretation of experiments within a laboratory team environment and a larger laboratory research program of engineers, physical therapists and neuroscientists focused on sensory motor performance and rehabilitation within a major, nationally leading Academic Rehabilitation Hospital.


The PostDoc Fellow consistently demonstrates support of the RIC statement of Mission and Philosophy by striving for excellence, contributing to the team efforts and showing respect and compassion for patients and their families, fellow employees, and all others with whom there is contact at or in the interest of the institute.


The PostDoc Fellow demonstrates RIC Core Attributes: Communication, Accountability, Flexibility/Adaptability, Judgment/Problem Solving, Customer Service and RIC Values (Hope, Compassion, Discovery, Collaboration, & Commitment to Excellence) while fulfilling job duties.


Principal Responsibilities: The PostDoc Fellow will participate in the discovery and evaluation of candidate targets affecting motor unit function and subsequent sensory motor performance following stroke, SCI, and/or ALS. The PostDoc Fellow may also be expected to study the effects of various clinical interventions in order to aid the design of rehabilitation strategies targeting specific motor unit properties.



  1. Design, execution and interpretation of experiments for the discovery of critical information in motor unit biology as it relates to the condition of-, or recovery from stroke, SCI and/or ALS.

  2. Independent leadership of research projects in a team environment

  3. Participates in regular development meetings with supervising team members.

  4. Keeps informed of developments in field to maintain and enhance professional expertise; offers suggestions regarding continuing development of program.

  5. Participates in research activities.


Reporting Relationships: Reports directly to assigned Research Scientist or Principal Investigator.


Knowledge, Skills & Abilities Required



  1. PhD degree in Biological or engineering Sciences.

  2. Excellent oral and written communication skills.

  3. Less than 5 years of postdoctoral training.

  4. Proficiency in the use of current electrophysiology and/or nerve conduction techniques and analyses, use of electromyography, kinematic measurements including active range of motion, peak velocity, peak acceleration, movement smoothness, and movement speed; and kinetic parameters, including isometric voluntary contraction and clinical measurements of motor impairment.

  5. General knowledge or interest in rehabilitation and/or bio- or mechanical engineering principles.

  6. Experience working with stroke, SCI or ALS subjects.

  7. Experience with clinical assessments related to movement (ie FIMS).

  8. Experience using or developing computer models is a plus.


Working Conditions: Normal laboratory environment within a hospital setting with little or no exposure to biohazard materials.


The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification.  They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of personnel so classified. 


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Link: https://ricc-hr.silkroad.com/epostings/index.cfm?fuseaction=app.dspjob&jobid=177362&company_id=16087
Employer: Rehabilitation Institute of Chicago
Location: Chicago, IL
Sector: Academia
Degree required: PhD, MD, PhD/MD
Conditions: ALS, stroke, SCI
Job posted: October 25th, 2016
Rehabilitation Institute of ChicagoChicago, ILPhD, MD, PhD/MDALS, stroke, SCIOct 25, 2016
Statistical Programmer

Statistical Programmer

(Click title to open job details in a new window.)
Description:

The Neuromuscular Program in the Department of Neurology at the University of Miami has an exciting opportunity for a full-time or part-time Statistical Programmer to join an active clinical and translational research group focused on therapy development for Lou Gehrig’s disease (Amyotrophic Lateral Sclerosis, or ALS). The statistical programmer will be an integral member of the research team and provide programming support for the cleaning, summarizing/reporting, and analysis of research data. The statistical programmer will work most closely with the biostatistician and the data manager. The appropriate title for the position will be contingent upon the selected candidate’s education and years of experience. Candidates with additional experience could be considered for a Sr. Statistical Programmer position.


The primary responsibilities are: Develop and implement strategies for real-time data QC. Conduct routine data checks to ensure data integrity. Write SAS macros and programs for data cleaning, reporting (e.g. tables, listings, figures), and the creation of analysis datasets. Construct view tables from a MySQL database. Perform statistical analyses defined in statistical analysis plans, as needed. Perform other related duties and responsibilities, as assigned.


The minimum requirements are: Bachelor’s or Master’s degree in statistics, biostatistics, mathematics, computer science, engineering, or a closely related analytical field and 1 year of relevant experience. Experience in SAS programming. Knowledge of SQL. Excellent verbal and written communication skills. Ability to multi-task and prioritize as necessary to meet deadlines. Ability to work within a team and as an individual contributor in a fast-paced and dynamic environment. Strong organizational and follow-up skills, as well as attention to detail. Any appropriate combination of relevant education, experience and/or certifications may be considered.


UHealth-University of Miami Health System, South Florida’s only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We’re the challenge you’ve been looking for.The University of Miami offers competitive salaries and a comprehensive benefits package including medical and dental benefits, tuition remission, vacation, paid holidays and much more. The University of Miami is an Equal Opportunity/Affirmative Action-Veteran/Disability Employer. Come join us!


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Link: https://um.hodesiq.com/job_detail.asp?JobID=5289386&user_id=&ViewAll=&emid=3640
Employer: University of Miami
Location: Miami, FL
Sector: Academia
Degree required: BSc, MSc
Conditions: ALS
Job posted: October 25th, 2016
University of MiamiMiami, FLBSc, MScALSOct 25, 2016
Technician B – Tom Maniatis Laboratory

Technician B – Tom Maniatis Laboratory

(Click title to open job details in a new window.)
Description:

The Maniatis lab is seeking a highly motivated Technician B to work on a project focusing on the progression of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). The technician will work closely with colleagues using techniques such as in vivo mouse genetics, gene expression profiling and in vitro cell culture assays. Comfortability with dissections preferred.


Principal Responsibilities:

Genotyping and general husbandry and maintenance of mouse colony; Real-time PCR analysis of gene expression; Cell culture of mouse pluripotent cells for differentiation into motor neurons and cortical cell isolation for astrocytes; RNA extraction and purification; Sectioning, in situ hybridization, and antibody staining of tissues for gene expression analysis; Cortical and spinal cord dissections.


Minimum qualifications:

B.Sc. or M.Sc. in Molecular Biology (or related field). At least 1 year of relevant laboratory experience preferred.


Additional qualifications:

The technician should be self-driven, accountable, and capable of performing experiments without direct supervision. Ability to clearly communicate data and findings in weekly meetings and presentations is necessary. Significant understanding of neurobiology and neurodegenerative disease;

Previous experience with mammalian cell culture is helpful, iPSC culture a bonus;

Exceptional organizational skills, attention to detail, strong interpersonal skills, and ability to maintain detailed written records of research;

Independence and a high degree of flexibility will be beneficial in a novel and rapidly changing research environment;


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Link: http://jobs.columbia.edu/applicants/Central?quickFind=158261
Employer: Columbia University
Location: New York, NY
Sector: Academia
Degree required: BSc
Conditions: ALS
Job posted: October 25th, 2016
Columbia University New York, NYBScALSOct 25, 2016
Postdoctoral Positions in Cellular Neuroscience and Neurogenetics/Bioinformatics

Postdoctoral Positions in Cellular Neuroscience and Neurogenetics/Bioinformatics

(Click title to open job details in a new window.)
Description:

The Rademakers Laboratory in the Department of Neuroscience at the Mayo Clinic Florida in Jacksonville, FL, USA, seeks applications from qualified candidates to complement our established neurogenetics research team. Multiple postdoctoral positions are available with specific needs in the areas of bioinformatics, cell biology and human induced pluripotent stem cell (iPSC) technology. Our laboratory aims to provide new insights into disease pathogenesis and to identify novel targets for therapy through the discovery and subsequent study of novel disease genes implicated in early-onset dementia’s including Alzheimer’s disease (AD), frontotemporal lobar degeneration (FTLD) and related disorders.


Successful candidates must be creative and must have the ability to find and apply innovative methods to biological questions. Individuals with a Ph.D. or M.D./Ph.D. are eligible to apply. Applicants must have excellent verbal and written communication skills and a strong record of peer-reviewed publications. They must have experience in two or more of the following areas: molecular biology, cell biology, human stem-cell biology, genome-editing, molecular genetics, genomics, computational biology/bioinformatics including the analysis of large next-generation sequencing datasets, and neuroscience. A solid knowledge of the neurobiology of relevant CNS disorders, such as AD, FTLD and/or amyotrophic lateral sclerosis will be considered a significant plus.


Mayo Clinic Jacksonville is one of the leading research establishments in neurodegenerative disorders in North America. The Rademakers Laboratory and adjacent Mayo research laboratories are well funded and well equipped. The campus and laboratories are located in sparse pine woodlands, a few minutes from the ocean and the intercoastal waterway of northern Florida.


Interested applicants for this position should sent by e-mail a curriculum vitae, a brief statement of research interest and the names and telephone numbers of three references to:


Rosa Rademakers PhD

Mildred A. and Henry Uihlein II Professor of Medical Research

Mayo Clinic Florida, Department of Neuroscience

Birdsall Building 207

4500 San Pablo Road, Jacksonville, FL 32224

Tel: 904 953 6279

e-mail: Rademakers.rosa@mayo.edu


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Link: http://www.nature.com/naturejobs/science/jobs/594991-postdoctoral-positions-in-cellular-neuroscience-and-neurogenetics-bioinformatics-at-mayo-clinic-florida
Employer: Mayo Clinic Florida
Location: Jacksonville, FL
Sector: Academia
Degree required: PhD, MD, PhD/MD
Conditions: ALS, FTD, NDG
Job posted: October 14th, 2016
Applications close: December 12th, 2016
Mayo Clinic FloridaJacksonville, FLPhD, MD, PhD/MDALS, FTD, NDGOct 14, 2016
Research Fellow / PhD Position

Research Fellow / PhD Position

(Click title to open job details in a new window.)
Description:

At TU Dresden the Junior Research Group of Dr. Jared Sterneckert, iPS Cells and Neurodegenerative Disease, of the Center for Regenerative Therapies Dresden (CRTD) is looking for a Research Fellow / PhD Position. Dr. Sterneckert’s group uses patient specific induced pluripotent stem (iPS) cells to generate models of neurodegenerative diseases, including Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS). Using a combination of gene editing, proteomics, and small molecules, we aim at understanding the mechanism(s) of pathogenesis and identifying novel treatments.


The aim of this PhD project is to use CRISPR-Cas9 to generate iPS cells carrying reporters for stress granule formation and autophagy in order to model ALS pathogenesis. A primary goal is to identify therapeutic small molecules using high-throughput screening. In collaboration with the teams of Anthony Hyman and Simon Alberti (both from MPI-CBG), we will characterize the biophysical states of ALS proteins in human motor neurons. This project is highly collaborative, involving multiple, international, and prestigious labs, and is sponsored by the European Union’s Joint Programme – Neurodegenerative Disease Research and funded by the BMBF.


Position and Requirements

– An outstanding university degree (Master or equivalent) in Biology, Biomedicine or similar

– Significant experience with cell culture. Experience with iPS cell culture and/or CRISPR/Cas9 mediated gene editing are preferred.

– Experience with molecular/biochemical methods, including Western blotting, plasmid construction/preparation, and immunofluorescence are helpful.


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Link: http://www.nature.com/naturejobs/science/jobs/594089-research-fellow-phd-position
Employer: Center for Regenerative Therapies Dresden
Location: Dresden, Germany
Sector: Academia
Degree required:
Conditions: NDG
Job posted: October 12th, 2016
Applications close: November 1st, 2016
Center for Regenerative Therapies DresdenDresden, GermanyNDGOct 12, 2016
Clinical Research Coordinator

Clinical Research Coordinator

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Description:

Cedars-Sinai Department of Neurology neuromuscular group is looking for an experienced Clinical Research Coordinator to join their research team. We are currently recruiting for over 10 protocols which include repositories, natural history studies, and interventional trials including pharmacological and surgical approaches.


The Clinical Research Coordinator II works independently providing study coordination including screening of potential patients for protocol eligibility, presenting non-medical trial concepts and details, and participating in the informed consent process. Responsible for accurate and timely source documents, data collection, documentation, entry and reporting including timely response to sponsor queries. Responsible for compiling and reporting each study including information at regular research staff meetings. May plan and coordinate strategies for increasing patient enrollment, improving efficiency, training of personnel, or identifying new research opportunities. Ensures compliance with all federal and local agencies including the Food and Drug Administration (FDA) and local Institutional Review Board (IRB).


Qualification Requirements/Preferences:

Educational Requirements: BS or BA degree


Experience: Four (4) years minimum of related experience clinical trial or research experience. Preferred familiarity with neurologic and/or neuromuscular disorders such as Amyotrophic Lateral Sclerosis (ALS) and Charcot Marie Tooth (CMT).


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Link: https://www.cedars-sinaimedicalcenter.apply2jobs.com//ProfExt/index.cfm?fuseaction=mExternal.showJob&RID=23719&CurrentPage=1&sid=69
Employer: Cedars-Sinai
Location: Los Angeles, CA
Sector: Academia
Degree required:
Conditions: ALS, NDG
Job posted: October 11th, 2016
Cedars-SinaiLos Angeles, CAALS, NDGOct 11, 2016
Clinical Research Coordinator

Clinical Research Coordinator

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Description:

The University of Miami’s Division of Neuromuscular Disorders in the Department of Neurology is seeking a full time Clinical Research Coordinator. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). To effectively perform in this position, the Clinical Research Coordinator will ideally have experience working on investigator-initiated clinical research projects, to be able to work independently with minimal supervision and to function effectively as part of a team.


The coordinator will be expected to:

– Acquire an in-depth understanding of the research program and the details of specific research projects.

– Acquire and maintain IRB approval for research studies as needed, including drafting protocol revisions, writing informed consent documents, developing and updating manual of procedures and case report forms.

– Recruit and enroll study participants, coordinate study visits, and assist with collection and quality control of study data.

– Maintain accurate and complete source documents and case report forms.


The minimum qualifications:

– Bachelor’s degree in a health related field.

– Three years of prior clinical research experience.

– Experience with the regulatory aspects of clinical research.

– Pay Band Min / Max: $46,400.00 – $83,600.00


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Link: https://um.hodesiq.com/job_detail.asp?JobID=5238818&user_id=&ViewAll=&emid=3640
Employer: Univ. of Miami
Location: Miami, FL
Sector: Academia
Degree required:
Conditions: ALS
Job posted: September 29th, 2016
Univ. of MiamiMiami, FLALSSep 29, 2016

Industry

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
Associate Scientist II, Neuroimmunology, Research

Associate Scientist II, Neuroimmunology, Research

(Click title to open job details in a new window.)
Description:

The Neuroimmunology department at Biogen is searching for a committed, enthusiastic and dependable associate scientist to assist with the design, execution and interpretation of preclinical studies for drug discovery and development. The incumbent will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative/neuroinflammatory diseases. He/she should be able to plan and execute in vivo and in vitro experiments with high level of independency, organization and scientific rigor. He/she should be able to maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members.


Qualifications:


•BS/MS in neurobiology, biology, or related field and a demonstrated track record of hands-on experience with in vivo and in vitro procedures

• Neuroinflammation/neurodegeneration background is highly preferable

• General molecular biology skills (DNA/RNA isolation, qPCR), knowledge of IHC/IF

• Experience with mammalian tissue culture techniques (primary cells and cell lines)

• Significant experience with protein analysis (Western blot, ELISA, protein extraction)

• Small rodent handling and dosing via standard delivery routes

• Imaging and FACS analysis preferable

• Strong commitment and high flexibility of work schedule is required


Education:  BS or MS degree in life science field.


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Link: https://jobs.biogen.com/job/Cambridge-Associate-Scientist-II%2C-Research-MA-02138/371072000
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: BSc, MSc
Conditions: NDG
Job posted: October 25th, 2016
BiogenCambridge, MABSc, MScNDGOct 25, 2016
Scientist I, Neuro Discovery, Research

Scientist I, Neuro Discovery, Research

(Click title to open job details in a new window.)
Description:

We seek an independent neuroscientist focused on identification of new targets for promoting axon regeneration, axon integrity and synapsis. The candidate will (1) be expected with the goal of delivering new targets to the clinic, focusing on multiple sclerosis and other neurodegenerative diseases, (2) apply in vitro and in vivo models to study the underlying mechanisms of degeneration and dysfunction in neurodegenerative diseases, (3) be familiar with cellular and animal models to study the effects of small molecules, antisense oligonucleotides, and antibodies for their roles in regeneration and repair, (4) enjoy membership amongst a highly productive and dynamic research team with many possibilities to collaborate internally and with external academic leaders, and (5) be expected to lead the project, present and publish their findings.


Qualifications: Candidates should (1) show extensive knowledge and hands-on experience with neuronal degeneration animal models, neuronal cell biology, neuron/glial cell interactions, (2) exhibit strong communication and collaborative skills, and (3) deliver in a dynamic and fast- moving research environment. A strong track record of relevant accomplishments and high-level publications is required.


Education: The successful candidate will have a Ph.D. in neuroscience or a related area with a productive postdoc training


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Link: https://jobs.biogen.com/job/Cambridge-Associate-Scientist-IIISr_-Associate-Scientist%2C-Research-MA-02138/344509100/
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD, MD, PhD/MD
Conditions: NDG
Job posted: October 25th, 2016
BiogenCambridge, MAPhD, MD, PhD/MDNDGOct 25, 2016
Scientist I/II, Research

Scientist I/II, Research

(Click title to open job details in a new window.)
Description:

The Biogen Epigenetics group seeks a highly motivated, creative scientist who will expand capabilities in epigenomic engineering within our Epigenetics and Cell & Gene Therapy groups, in consultation with colleagues in Neurology and Rare Disease groups. This scientist will have interests in the discovery and validation of mechanisms, pathways and potential drug targets for the treatment of neurodegenerative and rare diseases. S/he will create the means for the validation and modulation of targets of interest through the development of epigenomic engineering approaches for the modulation of disease-relevant target genes.


The ideal candidate will have an exemplary track record of scientific accomplishments, as reflected by a strong publication record, and will leverage evolving approaches in epigenetic research and epigenomic engineering to generate new opportunities for drug discovery. Experience in the investigation of epigenetic mechanisms and/or expertise in molecular and cell biology and an interest in epigenomic engineering are preferred. Research experience in epigenetic mechanisms underlying neurodegenerative and rare disease is highly desirable. Competitive candidates will be comfortable working in a fast-paced, dynamic, collaborative research environment, and will have a strong interest in translational research that will yield benefits to patients living with neurodegenerative and rare diseases.


Key Behaviors:

Engagement in hands-on bench work

Communication/influencing skills

Entrepreneurial spirit

Adaptable/flexible/agile

Creative/innovative/problem-solving


Education:

A Ph.D. in biochemistry, cell biology or a related discipline (background flexible), and 5+ years of postdoctoral/industrial experience


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Link: https://jobs.biogen.com/job/Cambridge-Scientist-III%2C-Research-MA-02138/354319200/
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD, MD, PhD/MD
Conditions: NDG
Job posted: October 25th, 2016
BiogenCambridge, MAPhD, MD, PhD/MDNDGOct 25, 2016
Scientist – Neuroscience FDE

Scientist – Neuroscience FDE

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Description:

Lilly Neuroscience is seeking an associate-level scientist (Bachelors or Masters) to join the Neurodegeneration Team to facilitate its mission of discovering novel medicines for the treatment of Alzheimer’s disease, Parkinson’s disease, and other related neurodegenerative conditions. The individual must possess a keen interest to understand the pathophysiological processes that underlie neurodegenerative conditions such as Alzheimer disease and have an exceptional attention to scientific detail.


Key Objectives/Deliverables:

Master several biochemical extraction techniques.

Execute biochemical assays, particularly ELISA, on a daily basis

Become proficient in developing/performing/problem solving multiple biochemical assay formats (ELISA and Western based)

Be proficient with Excel and Softmax Pro for data analysis

Perform data analysis, maintain and update notebook

Interact professionally on a daily basis with multiple labs

Basic Qualifications

Bachelor’s degree in Biochemistry, Pharmacology, or a related field

Minimum two years of post-degree academic or industry experience.

Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position


Additional Skills/Preferences

Strong skills and significant experience in developing/ performing/problem solving biochemical analyses (ELISA/Western blotting)

Experience in the area of Neurodegenerative disease

Industry experience in assay development and drug discovery.

Experience in developing novel biomarker assays

Exceptional learning agility and attention to detail

Strong skills and significant experience in developing/ performing/problem solving biochemical analyses (ELISA/Western blotting).

The applicant will be expected to have accurate and timely record keeping and strong data analysis and organizational skills.

Must be able to clearly communicate data to supervisor and be able to work independently.


Additional Information

This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.


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Link: http://jobs.sciencecareers.org/job/428029/scientist-neuroscience-fde/?TrackID=169008
Employer: Lilly Neuroscience
Location: Indianapolis, IN
Sector: Industry
Degree required: BSc, MSc
Conditions: NDG
Job posted: October 24th, 2016
Lilly NeuroscienceIndianapolis, INBSc, MScNDGOct 24, 2016
Research Scientist in Autoradiography

Research Scientist in Autoradiography

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Description:

AC Immune is seeking a highly qualified Research Scientist. The candidate must possess scientific background in structural biophysics and protein dynamics in neurodegenerative diseases and a clear record of accomplishment in an academic or a commercial setting. S/he will work on the discovery and characterization of PET radiotracers for the diagnosis of neurodegenerative disorders. Previous experience in neuroscience and neurodegenerative disorders, notably ALS and FTD along with TDP-43, is an advantage. S/he must have demonstrated their ability to make significant discoveries in an academic setting or bring a research product to a clinical stage.


Job description:

• Preparation and characterization of human brain tissue for binding studies

• Evaluation of new procedures and protocols for the enrichment of pathological protein aggregates from human tissues (e.g. immunoprecipitation, sucrose gradient, FACS)

• Setting up autoradiography assay conditions for new radioligands on human and TG mouse tissue sections

• Screening small molecule compounds

• Immunostaining of human tissue sections

• Autoradiography with tritiated ligands


Qualifications.

• Ph.D. training in life sciences

• Previous experience in structural biophysics and protein dynamics

• Postdoctoral experience is an advantage

• Excellent oral and written skills in English is mandatory


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Link: http://www.acimmune.com/content/images/RS_2.pdf
Employer: AC Immune
Location: Lausanne, Switzerland
Sector: Industry
Degree required:
Conditions: ALS, NDG
Job posted: October 13th, 2016
AC ImmuneLausanne, SwitzerlandALS, NDGOct 13, 2016

Non-Profit and Government

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
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