To submit any new job opportunities for this list, please email ALSjobs@prize4life.org. List the employer, location, closing date if applicable, and a link to more information. Jobs are removed after 3 months, unless requested otherwise.
This free job bulletin board aims to help scientists identify job opportunities in the field of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Positions described as broadly spanning neurodegenerative diseases (NDG) are noted as ‘NDG‘. The job listing includes research positions at all levels, as well as non-research positions for which a research background at the MS, PhD, or MD level is required.
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Academia
| Job Title | Employer | Location | Degree | Conditions | Date Posted ▾ |
|---|---|---|---|---|---|
NEW! Assistant or Associate Professor of NeurologyAssistant or Associate Professor of Neurology(Click title to open job details in a new window.)Description: The Department of Neurology of Columbia University invites applications for a tenure-track faculty position at the rank of Assistant or Associate Professor. We seek a neurologist with specialty training in neuromuscular medicine, with particular expertise in the care of patients with amyotrophic lateral sclerosis (ALS). The successful candidate will have a primary affiliation with the Eleanor and Lou Gehrig ALS Center in the Neuromuscular Medicine Division, and will focus on the care of patients with ALS and other neuromuscular disorders, including those seen in the ALS and neuromuscular clinics. In addition to supporting the clinical activities of the ALS Center, the position will expand its basic, translational and/or clinical research program. Candidates with research interests in the genetics and basic biology of motor neuron disease, the development of novel ALS therapeutics, biomarker development or brain imaging are especially encouraged to apply. As a member of the Motor Neuron Center at Columbia, the new clinician-investigator will have the opportunity to interact and collaborate with a diverse group of individuals in basic science and clinical departments within the University. The ideal candidate will have extramural funding for research. Link: https://academicjobs.columbia.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1527111978983 Employer: Columbia University Location: New York, NY Sector: Academia Degree required: MD or MD/PhD Conditions: ALS Job posted: May 23rd, 2018 | Columbia University | New York, NY | MD or MD/PhD | ALS | May 23, 2018 |
NEW! Assistant Professor, Cell and Molecular BiologyAssistant Professor, Cell and Molecular Biology(Click title to open job details in a new window.)Description: The George and Anne Ryan Institute for Neuroscience and the Department of Cell and Molecular Biology invite applications for the position of Assistant Professor. The successful candidate will have an appointment in the Department of Cell and Molecular Biology (CMB) in the College of the Environment and Life Sciences. The candidate will be expected to establish a basic science or translational research program in an area that complements the mission of the Ryan Institute and the Department of Cell and Molecular Biology, and is supported by extramural funding. The successful candidate will also contribute to the University’s teaching mission and participate in service activities. The Ryan Institute is an interdisciplinary research institute that is focused on discovering and developing disease-modifying therapies for neurodegenerative diseases. CMB is a research and teaching department focused on the cellular and molecular basis of physiology and disease. We are building a faculty with a strong record of successful laboratory and/or clinical research that support our mission of integrating discovery science, translational medicine, education and community engagement to identify and deliver tomorrow’s treatments today. Responsible for managing and maintaining the COP Heber Youngken Medicinal Garden including plants in Avedisian Hall, COP assigned greenhouse(s), and surrounding COP courtyard environs. Lead students, faculty, and garden volunteers to enable use of Medicinal Garden for research, teaching, public education and outreach. Visit the URI jobs website at: https://jobs.uri.edu to apply and view complete details for job posting (F00087). Please attach the following 3 (PDF) documents to your online Faculty Employment Application: (#1) Cover letter including a description of how your qualifications match the requirements for the position, (#2) Curriculum Vitae, which should include the names and contact information for three professional references, and (#3) “Other Document” a research statement or sample(s) of relevant scholarly work (as one complete document). Application Deadline: This is an open until filled search. First consideration will be given to applications received by June 17, 2018. Share this:         Link: https://neurojobs.sfn.org/jobs/11056889/asst-professor-the-george-and-anne-ryan-institute-for-neuroscience-and-cell-and-molecular-biol Employer: University of Rhode Island Location: Kingston, RI Sector: Academia Degree required: PhD Conditions: NDG Job posted: May 16th, 2018 | University of Rhode Island | Kingston, RI | PhD | NDG | May 16, 2018 |
NEW! Bioinformatics SpecialistBioinformatics Specialist(Click title to open job details in a new window.)Description: The VIB-KU Leuven Center for Brain & Disease Research is seeking a highly motivated Single Cell Bioinformatics Specialist. You will collaborate with the 17 research groups within the Center and provide essential input on computational biology aspects of their research projects. In this job you will be confronted with exciting research questions in neurobiology and neurodegeneration; and with a broad spectrum of computational challenges and single-cell omics data sets. You will work closely with in the Laboratory of Computational Biology (Stein Aerts Lab) and with the single cell expertise unit (Suresh Poovathingal) and you will be part of an active bioinformatics community in Leuven, allowing daily interactions with colleague bioinformaticians. For additional information concerning this job please contact Prof. Stein Aerts. To apply, submit your application to our website. Please include in your application your CV (including a list of your scientific publications, and the names and contact information of 3 references) as well as a cover letter describing your motivation, previous research experience and background. Please provide also a track record of previous coding work, e.g. include your github web address. Link: https://vibvzw.jobsoid.com/j/11971/single-cell-bioinformatics-specialist Employer: VIB Location: Leuven, Belgium Sector: Academia Degree required: MSc or PhD Conditions: NDG Job posted: May 16th, 2018 | VIB | Leuven, Belgium | MSc or PhD | NDG | May 16, 2018 |
NEW! Principal ScientistPrincipal Scientist(Click title to open job details in a new window.)Description: Purpose: This person will work closely with members of the R&D organization, CROs, consultants, corporate collaborators as well as the senior leadership team to ensure development and execution of drug discovery projects according to company goals. This person will report to the SVP of Translational Sciences. Essential Job Responsibilities:
Quantitative Dimensions:
Qualifications: Required
Preferred
Link: https://astellascareers.jobs/cambridge-ma/principle-scientist-research-fellow/8FE07F4785A848658683CC64D5A32259/job/? Employer: Astellas Pharma Location: Cambridge, MA Sector: Academia Degree required: PhD Conditions: NDG Job posted: May 16th, 2018 | Astellas Pharma | Cambridge, MA | PhD | NDG | May 16, 2018 |
NEW! Research SpecialistResearch Specialist(Click title to open job details in a new window.)Description: A Lead Research Specialist position is available in the Center for Neurodegenerative Disease to join a dynamic research environment that uses a wide range of techniques and technologies to study neurodegenerative disease (e.g., Alzheimer’s disease, amyotrophic lateral sclerosis) pathogenesis. The successful applicant will be self-motivated and capable of working both independently and as a member of a team. Responsibilities will include assisting with the procurement and banking of human autopsy brain specimens and with distribution of tissue and biospecimens to investigators. He/she will also share responsibility for histological and immunohistochemical staining of human and rodent tissues. The successful applicant will be familiar with and train users in the proper use of shared laboratory equipment, and will share responsibility for maintaining the laboratory, including monitoring the storage and disposal of hazardous substances, ordering supplies, calibrating and performing routine repair and maintenance of equipment, interfacing with service personnel for equipment repairs, and maintaining and documenting laboratory safety standards. Upon hiring, the employee must complete the Laboratory Safety Training class and undergo immunization against potentially hazardous agents, as required by Emory University policy. Basic computer experience (Microsoft Word, Excel, etc.) and strong organizational and record-keeping skills are essential. Experience with Western blotting, confocal microscopy, tissue sectioning, histology and/or immunohistochemistry is highly desirable. Link: https://staff-emory.icims.com/jobs/20322/research-specialist%2c-lead/job?hub=13&mobile=false&width=1150&height=500&bga=true&needsRedirect=false&jan1offset=-300&jun1offset=-240 Employer: Emory University Location: Atlanta, GA Sector: Academia Degree required: BS Conditions: ALS Job posted: May 15th, 2018 | Emory University | Atlanta, GA | BS | ALS | May 15, 2018 |
NEW! Postdoctoral Fellow, Zhang LabPostdoctoral Fellow, Zhang Lab(Click title to open job details in a new window.)Description: Postdoctoral positions are available at the University of Wisconsin-Madison to study neural stem/progenitor cell self-renewal /reprogramming and functional dissection / therapeutic implication of human neural cells in neurological disorders. PhD or equivalent in cell / molecular / developmental biology, neuroscience, or chemistry is required. Experiences in electrophysiology, small animal microsurgery, genome editing, or 3D printing are highly desirable. Compensation follows the NIH standard. The Zhang laboratory is a leading group studying neural specification of human pluripotent stem cells and application of stem cells in developing therapeutics for neurological diseases (e.g., Cell Stem Cell, 2014, 2015, 2016, Nature Biotechnology, 2016, Nature Medicine, 2016, Nature Communication, 2017, Stem Cell Reports 2017/18). It is located in the NIH-sponsored Waisman Center that is dedicated for studying human development, developmental disability, and neurodegenerative diseases. Candidates enthusiastic in pursuing regenerative sciences are welcome to join this vibrant group in the beautiful city of Madison. Link: https://www.nature.com/naturejobs/science/jobs/644297-postdoctoral-positions-in-stem-cells-and-neural-regeneration Employer: University of Wisconsin Location: Madison, WI Sector: Academia Degree required: PhD Conditions: ALS Job posted: May 14th, 2018 | University of Wisconsin | Madison, WI | PhD | ALS | May 14, 2018 |
NEW! Bioinformatics SpecialistBioinformatics Specialist(Click title to open job details in a new window.)Description: A Bioinformatics Staff Scientist position is available at the DZNE in Tübingen within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink. The research focus of our group is to identify genetic risk factors for neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Frontal-Temporal Dementia/Motor Neuron Disease, Progressive Supranuclear Palsy and Ataxia in close collaboration with our clinical partners. As partners in the International Parkinson’s Disease Genomics Consortium (IPDGC) (http://pdgenetics.org/), we participate in large scale genetic and genomic studies to identify new genetic risk factors and to characterize the biological consequences of these mutations and risk factors by using automated high-throughput cellular screens combined with genomic and transcriptomic approaches. For further details on the scientific program of the group, please refer to http://www.dzne.de/en/sites/tuebingen/research-groups/heutink.html. To apply, submit your application online: https://jobs.dzne.de/en/jobs/184/form . Link: https://www.nature.com/naturejobs/science/jobs/644277-bioinformatics-staff-scientist-f-m Employer: German Center for Neurodegenerative Diseases (DZNE) Location: Tübingen, Germany Sector: Academia Degree required: PhD Conditions: ALS, FTD Job posted: May 13th, 2018 | German Center for Neurodegenerative Diseases (DZNE) | Tübingen, Germany | PhD | ALS, FTD | May 13, 2018 |
Graduate Studentship, Locker LabGraduate Studentship, Locker Lab(Click title to open job details in a new window.)Description: Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS) areneurodegenerative disorders (NDs) with proteostasis defects. They represent an ideal set of diseases covering >70% of patients to increase our understanding of the molecular basis of NDs. The associated pathologies are difficult to truly model and compare using animals because (i) they are mainly caused by sporadic forms of the diseases, and (ii) models do not recapitulate the basic cellular changes observed in patients. Our aim is to achieve a global understanding of RNA translation and stress granules regulation across these neurodegenerative diseases using novel genetically engineered isogenic human stem cell lines. This will identify key regulatory nodes, across diseases, revealing new points for therapeutic interventions.The PhD candidate will work as part of an EU/MRC-funded trans-national consortium that has developed control fibroblasts genetically engineered into disease cell lines (project grant MR/R02426X/1), allowing studies within identical genetic backgrounds. Following training with our project partners at McGill (Canada) and QMUL (UK), the control and disease-model iPSCs will be used to differentiate neuronal cell populations including forebrain cortical-like neurons, midbrain dopamine-like and glial astrocyte-like cells. Subsequently, the candidate will be trained in confocal microscopy techniques to detect and quantity stress granules in cells, measure translational activity globally and specifically at the mRNA level using ribosomes profiling. Applicants are expected to hold a good honours degree (upper second) in an appropriate discipline, but prior experience in research or industry may be acceptable. Enthusiasm for, and commitment to, independent study is essential. The appointed candidate will supported by a Medical Research Council grant (MR/R02426X/1: £310.088,70) awarded to N.Locker , for 3 years of PhD studies within which the candidate is expected to submit their PhD thesis. The studentship rates and minimum doctoral stipend will align to UKRI guidelines as follows: stipend for 2017/18 is £14,553; fee 2017/18 is £4,195. This will also cover bench fees associated with the projects, small equipment, travels for training purpose and conference attendance. For further details and an informal discussion please contact Dr Nicolas Locker at n.locker@surrey.ac.uk prior to submitting an application. Formal applications should be submitted through our Biosciences and Medicine programme page. You should make clear in your application that you are applying for this studentship. You should also submit a cover letter stating that you are a UK/EU national and willing to go through the required security vetting process. Link: https://jobs.surrey.ac.uk/vacancy.aspx?ref=035218 Employer: University of Surrey Location: Guildford, England Sector: Academia Degree required: BS Conditions: ALS Job posted: May 11th, 2018 | University of Surrey | Guildford, England | BS | ALS | May 11, 2018 |
Group Leader, NeurobiologyGroup Leader, Neurobiology(Click title to open job details in a new window.)Description: The Neurobiology Division of the Medical Research Councils Laboratory of Molecular Biology (MRC LMB) invites applications for a Programme Leader-Track position. We seek a scientist with a focus on the elucidation of fundamental molecular mechanisms that determine the structure and function of the neuronal synapse, in health and disease. An emphasis on the development and application of molecular neurobiological approaches is essential, and the application of cutting-edge light and/or electron microscopic imaging is encouraged. The primary selection criteria are scientific excellence and potential for synergy with our existing research programmes, both within the Division (encompassing neuronal molecular cell biology, neural circuits and simple behaviours, and the molecular/ cell biological basis of neurodegeneration) and across the wider LMB. You should hold a PhD and have an excellent publication record, be internationally recognised for your work and have outstanding potential for independent research. The position comes with substantial core funding sufficient to establish your research group, and applications for additional external grant support are encouraged. The LMB has an exceptional record of ground-breaking research, and in 2013 moved into a new building with outstanding core facilities including those for light and electron microscopy and mass spectrometry, as well as electronic and instrumentation workshops. Administrative duties are minimal and no teaching is required. Interactions across the four Divisions of the LMB are encouraged. The University of Cambridge and affiliated institutions form a vibrant Neuroscience community (http://www.neuroscience.cam.ac.uk/). The appointment will be made at Programme Leader-Track level, and candidates should have a strong international track record of relevant independent research and an ability to lead a research team, pursuing original approaches to long-term research goals. Find out more about the LMB’s Neurobiology Division at http://www2.mrc-lmb.cam.ac.uk/research/neurobiology/. Informal enquiries can be addressed to Head of Division, Michael Hastings (mha@mrc-lmb.cam.ac.uk). For further information about the MRC visit www.mrc.ac.uk To apply, submit your application online. Applications should include a covering letter and full CV, an outline of current research interests (1 page) and a proposal for future research (up to 2 pages), along with the names and addresses of three professional referees who have agreed to be contacted prior to interview. Link: https://mrc.tal.net/vx/mobile-0/appcentre-ext/brand-3/candidate/so/pm/4/pl/1/opp/834-Programme-Leader-Track-Neurobiology-Dr-Michael-Hastings-LMB-834/en-GB Employer: UKRI MRC Laboratory of Molecular Biology Location: Cambridge, England Sector: Academia Degree required: PhD Conditions: NDG Job posted: May 10th, 2018 | UKRI MRC Laboratory of Molecular Biology | Cambridge, England | PhD | NDG | May 10, 2018 |
Research Technologist, Morrison and Rothstein LabsResearch Technologist, Morrison and Rothstein Labs(Click title to open job details in a new window.)Description: A Research Technologist to work in the laboratories of Drs. Brett Morrison and Jeffrey Rothstein in the Department of Neurology. Our laboratories study the pathogenesis of the devastating motor neuron disease, amyotrophic lateral sclerosis (ALS; commonly referred to as Lou Gehrig’s disease). A particular focus is on the role played by oligodendrocytes, a key support cell in the brain that is dysfunctional and degenerates in ALS. Specific duties & responsibilities: The responsibilities of the individual in this position will be to independently pursue new projects as well as work collaboratively with the other members of the lab (principal investigators, post-docs, graduate students, and research technicians) on ongoing projects. In addition to performing laboratory experiments, ongoing responsibilities will include the management of a transgenic mouse colony, assisting the laboratory manager with the ordering of laboratory supplies, and attending all required laboratory meetings. Link: https://jobs.jhu.edu/job/Baltimore-Research-Technologist-MD-21205/437413200/ Employer: Johs Hopkins University Location: Baltimore, MD Sector: Academia Degree required: BA or BS Conditions: ALS Job posted: May 10th, 2018 | Johs Hopkins University | Baltimore, MD | BA or BS | ALS | May 10, 2018 |
NeurologistNeurologist(Click title to open job details in a new window.)Description: The Peripheral Nervous System, Muscle and ALS Department, Pasteur 2 new Hospital, CHU de Nice (France) is actually seeking a Neurologist with immediate availability for a Clinical and Research position. This department is certified as Neuromuscular Diseases Reference Center and ALS Reference Center. These Centers are affiliated to French rare diseases Healthcare Network (FILNEMUS) and French rare diseases Healthcare Network: Amyotrophic lateral sclerosis and rare motor neuron diseases (FILSLAN). The Department has also been labeled as being part of the European Reference Networks-NeuroMuscular Diseases (ERN-NMD) as Center of Excellence. With an active file of more than 2000 patients, the department is particularly involved in diagnosis and multidisciplinary care of patients suffering from myopathies, myasthenia, peripheral neuropathies and ALS. This activity implies consultations, day and week hospitalizations sectors. It is composed of an electrophysiology platform and possesses the necessary means for the performance and the analysis of muscle or nerve biopsies. The Physicians from the Department are particularly involved in Clinical and Fundamental Research projects in connection with IRCAN from the University of Nice- Sophia Antipolis- Faculty of Medicine, INSERM U1081 – CNRS UMR 7284 and INRIA. We participate in industrial Therapeutic Trials. The Department is part of the Pole of Clinical Neurosciences, Central Nervous System department and the Neurovascular Unit which are located in the same Hospital. It contributes to ensure the continuity and constant care of patients suffering from neurologic diseases. The required skills for application are the following: *Having a Medical Doctor Thesis and possessing a Diploma of specialty in Neurology which is recognized in France Dynamism and willingness of being involved in Research projects will be highly appreciated qualities. Interested candidates will beforehand contact Pr Sacconi- Head of Department. They will send their CV containing their Title and works, and a cover letter in French . Pr Sabrina SACCONI Système Nerveux Périphérique, Muscle et SLA Link: https://en.academicpositions.fi/ad/chu-de-nice/2018/neurologist-with-immediate-availability-for-a-clinical-and-research-position/112120 Employer: Centre Hospitalier Universitaire de Nice Location: Nice, France Sector: Academia Degree required: MD Conditions: ALS Job posted: May 5th, 2018 | Centre Hospitalier Universitaire de Nice | Nice, France | MD | ALS | May 05, 2018 |
Postdoctoral Fellow, Baker LabPostdoctoral Fellow, Baker Lab(Click title to open job details in a new window.)Description: You will contribute to a major new project, funded by the William Leech Charity, to generate a primate model of motor neuron disease. Click here for further details. You will be responsible for the day-to-day running of the project, gathering electrophysiological and imaging data. You will perform computational analysis of the data, and will produce the first draft of manuscripts to publish the results. A PhD in Neuroscience or related discipline is essential, and experience with primate electrophysiology, MRI, and writing MATLAB scripts for data analysis would be an advantage. Salary: £29,799 to £31,604 per annum. Excellent team skills are required to liaise with the many staff members with roles in this project, and a strong commitment to animal welfare and 3Rs. The post is tenable until the end of March 2021. Informal enquiries to stuart.baker@ncl.ac.uk.
Link: https://vacancies.ncl.ac.uk/ViewVacancyV2.aspx?enc=mEgrBL4XQK0+ld8aNkwYmPgqa2Bp8pKqUS0pcNJvPheq+F+nQpHjpgLFPSxGTB+fOXxJTqYeWpcpBRlocM7s+5d2grqSaU7XcU8wUruEjst66FGyfB/K9AaxsyS8w+qz5qWCjFbmsz5xSVTvz8EVUw== Employer: Newcastle University Location: Newcastle Upon Tyne, England Sector: Academia Degree required: Conditions: ALS Job posted: May 4th, 2018 Applications close: May 18th, 2018 | Newcastle University | Newcastle Upon Tyne, England | ALS | May 04, 2018 | |
Postdoctoral Fellow, Liachko labPostdoctoral Fellow, Liachko lab(Click title to open job details in a new window.)Description: A postdoctoral research position is available in the Liachko lab located at the Veterans Affairs hospital in Seattle, and affiliated with the University of Washington (http://depts.washington.edu/geront/directory/bios/liachko.html). We use model systems including mouse primary neurons, cultured human cells and C. elegans, to study the neurodegeneration seen in amyotrophic lateral sclerosis, Alzheimer’s disease, and other aging related disorders. We are seeking a motivated post-doctoral fellow who works well with others as part of a research team. The ability to design, conduct, and report on research experiments is required. Communication skills, organizational skills, and a willingness to learn new approaches are of paramount importance. The fellow will pursue the underlying causes of aging associated protein aggregation in neurodegenerative disease using primary neuron, cell culture, and/or transgenic C. elegans models. Knowledge/ Skills necessary:
Desirable Experience/Skills:
Requirements: A PhD in the biomedical science, the ability to fulfill responsibilities listed above, and eligibility and willingness to apply for external postdoctoral funding including T32/F32 NIH training grants or other independent funding sources. Self- motivation is essential Salary: $66,000.00 to $79,000.00 /year Link: https://www.indeed.com/q-Post-Doctoral-Research-Associate-jobs.html?vjk=feb8c4a6e38047c3 Employer: VA Hospital Location: Seattle, WA Sector: Academia Degree required: PhD Conditions: ALS Job posted: May 3rd, 2018 | VA Hospital | Seattle, WA | PhD | ALS | May 03, 2018 |
Postdoctoral FellowshipPostdoctoral Fellowship(Click title to open job details in a new window.)Description: The European Bioinformatics Institute (EMBL-EBI), the NIHR Cambridge Biomedical Research Centre (BRC) and the University of Cambridge School of the Biological Sciences (SBS) are now accepting applications for joint postdoctoral fellowships, supporting projects that apply computational approaches to translational clinical or biological research. EBPOD fellowships support three-year projects supervised jointly by faculty members at EMBL-EBI and either the Cambridge BRC or the University of Cambridge’s School of the Biological Sciences. We are looking for self-directed, focused scientists with a profound interest in clinical or translational research, who enjoy working through a problem computationally. We offer an opportunity to apply your skills and energy for the greater good, working in one of the world’s most outstanding research environments. For full information on the EBPOD fellowships please click here Project details For full on this project please click here Application Instructions 1. A cover letter specifying the project you are applying for (see the list on this page); The deadline for submission of the online application and self-proposed projects is Friday, 20 July 2018 (23:00 BST) Link: https://www.embl.de/jobs/searchjobs/index.php?ref=EBI_01198&newlang=1&srch_trm=EBPOD%20Fellowship: Employer: European Molecular Biology Laboratory Location: Hinxton, England Sector: Academia Degree required: PhD Conditions: ALS Job posted: May 1st, 2018 Applications close: July 20th, 2018 | European Molecular Biology Laboratory | Hinxton, England | PhD | ALS | May 01, 2018 |
Physician, Physical Medicine & RehabilitationPhysician, Physical Medicine & Rehabilitation(Click title to open job details in a new window.)Description: The ideal candidate would be preferably Physical Medicine & Rehabilitation (PM&R), Spinal Cord Injury/Dysfunction fellowship-trained. Experience in Spinal Cord Injury-Disability (SCI-D), Spinal Cord Injury (SCI), Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), PM&R. Board Certified/Board Eligible in SCI is preferred. Candidates with board certification or board eligibility in SCI are eligible to apply regardless of residency specialization, and will be given preference in the application, but fellowship is not exclusively required if residency training is in PM&R. Link: https://www.vacareers.va.gov/job-search/job-detail.asp?job=324576 Employer: Veterans Affairs Principal investigator: Veterans Health Administration Location: St. Louis, MO Sector: Academia Degree required: MD Conditions: ALS, SCI Job posted: April 29th, 2018 | Veterans Affairs | St. Louis, MO | MD | ALS, SCI | Apr 29, 2018 |
Research Associate, Svendsen LabResearch Associate, Svendsen Lab(Click title to open job details in a new window.)Description: The Svendsen Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking personnel to join our dynamic group. The ideal incumbent should have experience in managing and analysis of large datasets using programming languages such as Python and R, and an interest in working hands on with stem cells and organ-on-chip technology with a focus on research in neurodegenerative diseases (Brain-on-Chip). Ideal candidate will also have experience in machine learning approaches for use in automation of laboratory equipment and analysis of complex bioinformatic datasets. Working with the PI and scientists, the Research Associate I (RA I) performs a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research, including the Brain-on-Chip program. RA I is responsible for the generation and curation of acquired data, implementation of analysis programs, and generation of scripts to assists in laboratory activities and research aims. RA I is responsible for general laboratory activities including maintenance of reagents, ordering and stocking of supplies. RA I keeps accurate and detailed records of experiments and results. RAH assists in the operation of specialized equipment and machinery, including the culture of human stem cell derived tissues. Observes safety standards and procedures. This position may include supervisory responsibilities. Daily Duties will include the following: – Performs a variety of routine laboratory tasks and procedures. – Works with laboratory staff to develop and implement analysis frameworks for use in biomarker and therapeutic target discovery – Keeps accurate and detailed project records of experiments and results. – Maintains lab equipment and related records. – Transports, processes and logs samples. – Maintains computer database with relevant information – implements scripts for the analysis of complex imaging and multi-omic analysis datasets. – Performs lab maintenance duties, including glassware cleaning and sterilization, – Maintains stocks of general lab materials, and places orders for lab equipment and supplies. – Assists new students and fellows at the laboratory. – Assists in the operation of specialized equipment and machinery. – Observes and complies with safety standards arid procedures. – Histology and Microscopy – Sectioning of tissue specimens – Staining of tissue specimens to include special stains and INC. Additional Information: Scheduling flexibility including evening, weekend and holiday rotation commitment is required. Travel may be required. Link: https://main.hercjobs.org/jobs/10986710/research-associate-i-stem-cells Employer: Cedars-Sinai Medical Center Location: Los Angeles, CA Sector: Academia Degree required: BA or BS Conditions: ALS Job posted: April 28th, 2018 | Cedars-Sinai Medical Center | Los Angeles, CA | BA or BS | ALS | Apr 28, 2018 |
Postdoctoral Fellow, Ferraiuolo and El-Khamisy LabsPostdoctoral Fellow, Ferraiuolo and El-Khamisy Labs(Click title to open job details in a new window.)Description: Applications are invited for the post of Postdoctoral Research Associate in the laboratories of Dr Ferraiuolo and Prof Your project, funded through the AZ Postdoctoral Programme, aims to investigate the role of astrocytes derived from MND You will have a strong background in molecular and cellular (neuro) biology with experience in a range of molecular and Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVFODkyOTJERTc1QzExOTEyOTMmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos# Employer: University of Sheffield Location: Sheffield, England Sector: Academia Degree required: PhD Conditions: ALS Job posted: April 27th, 2018 Applications close: May 28th, 2018 | University of Sheffield | Sheffield, England | PhD | ALS | Apr 27, 2018 |
Research TechnicianResearch Technician(Click title to open job details in a new window.)Description: The laboratory is seeking a motivated and enthusiastic candidate with experience in stem cell culture and molecular biology to support preclinical studies related to Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease) and pain. Working independently under the direction of the Principal Investigator, the research technician will assist in ongoing translational studies. The major responsibilities will include stem cell culture and differentiation, as well as general molecular biology techniques such as immunohistochemistry, RNA isolation and PCR to analyze the cells of interest. Additional work will include assistance with ordering, laboratory maintenance and animal husbandry. Link: https://partners.taleo.net/careersection/ex/jobdetail.ftl?job=3063589&lang=en Employer: Massachusetts General Hospital Location: Charlestown, MA Sector: Academia Degree required: BA or BS Conditions: ALS Job posted: April 27th, 2018 | Massachusetts General Hospital | Charlestown, MA | BA or BS | ALS | Apr 27, 2018 |
Research AssistantResearch Assistant(Click title to open job details in a new window.)Description: The Rockefeller University seeks a Research Assistant to join Laboratory of Molecular Biology. The Research Assistant will contribute to a project examining the molecular mechanisms of neurodegenerative and psychiatric disorders. The Research Assistant will be responsible for performing molecular techniques, including TRAP, RNA-seq, in situ hybridization, and immunohistochemistry, to examine cell type specific gene expression profiles in the mouse brain. Will complete rodent surgeries, behavioral assays, and functional imaging of brain immunohistochemistry. Will be responsible for maintaining genetically altered mouse lines and completing other routine laboratory duties as needed. Bachelor’s degree in science required; educational emphasis in neuroscience preferred. Must have experience with basic molecular biology techniques, fluorescent imaging, and handling laboratory animals. Must have computer skills and be proficient in Microsoft Excel. Must be organized, have excellent communication skills, and keep clear, accurate records. Link: https://main.hercjobs.org/jobs/10965886/research-assistant Employer: Rockefeller University Location: New York, NY Sector: Academia Degree required: BA or BS Conditions: NDG Job posted: April 21st, 2018 | Rockefeller University | New York, NY | BA or BS | NDG | Apr 21, 2018 |
Assistant or Associate Professor, NeuroscienceAssistant or Associate Professor, Neuroscience(Click title to open job details in a new window.)Description: The Department of Neurosciences, Case Western Reserve University School of Medicine invites applications for a tenure-track faculty position at the rank of Assistant or Associate Professor. We seek applicants who utilize innovative methodological approaches to investigate basic mechanisms of neural development, regeneration, or neural circuit function and how perturbation of these mechanisms contributes to neurological, neurodegenerative, and/or psychiatric diseases. The new investigator will have the opportunity to interact and collaborate with a diverse group of individuals in basic science and clinical departments within the School of Medicine, University Hospitals Cleveland Medical Center, Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, and MetroHealth Medical Center. Case Western Reserve University has an outstanding infrastructure for biomedical research including recently renovated animal facilities and core facilities supporting state-of-the-art methodologies in cellular and whole animal imaging, behavioral analyses, and proteomics and genomics. Case Western Reserve University School of Medicine has committed significant resources for major expansion of neuroscience research. Applicants for a position as Assistant Professor should have a Ph.D. and/or M.D. degree, 3 to 5 years postdoctoral experience, and a strong record of scholarly activity. Candidates for appointment as Associate Professor should have these credentials and be nationally recognized scholars with a strong, externally funded research program. Applications should include a cover letter, curriculum vitae, statement of research interests, names of three references and be submitted electronically at apply.interfolio.com/49561. The Interfolio application site will open on April 20th and close on June 20th. For technical questions about your application, please contact Interfolio directly at 877-997-8807 or help@interfolio.com. Link: http://apply.interfolio.com/49561 Employer: Case Western Reserve University Location: Cleveland, OH Sector: Academia Degree required: PhD Conditions: NDG Job posted: April 20th, 2018 Applications close: June 20th, 2018 | Case Western Reserve University | Cleveland, OH | PhD | NDG | Apr 20, 2018 |
Assistant or Associate Professor, PathologyAssistant or Associate Professor, Pathology(Click title to open job details in a new window.)Description: The Department of Pathology in the Rady Faculty of Health Sciences, University of Manitoba invites applications for a full-time tenured or tenure-track position at the Assistant or Associate Professor level, commencing on July 1, 2018, or on a date mutually agreed upon. The Department seeks an emerging scholar with a commitment to excellence in research and teaching. Outstanding candidates in any area of developmental neurobiology / developmental neuropathology will be preferred. A competitive start-up package will be provided. Salary and rank will be commensurate with experience and qualifications. The new recruit is expected to develop and maintain a rigorous and independently funded research program that will preferably complement or extend the department’s strengths in perinatal and developmental neuropathology. Other duties will include undergraduate teaching, graduate teaching and supervision, and service-related activities. The successful candidate will have a Ph.D. and at least 2 years relevant post-doctoral research experience; a track record of high quality scholarly research leading to peer reviewed publications; will have, or demonstrate the potential to establish an independent, innovative, scholarly, externally fundable research program and will have demonstrated strength in or strong potential for teaching contributions. Experience with working with human tissue is particularly desirable. Preference will be given to candidates with demonstrated evidence of the ability to work in a collaborative environment. Application materials, including letters of reference, will be handled in accordance with the Freedom of Information and Protection of Privacy Act (Manitoba). Applications will be accepted until May 15, 2018 or until the position has been filled. Applications must include: a cover letter, a curriculum vitae, a summary of research interests, a three page research plan (covering the first year and 3-5 years), a description of teaching philosophy, and the names and contact information of three referees for letters of reference (in a single PDF file). Please ensure to specify position number 25772 in the application. Applications should be addressed to the chair of the search committee: Dr. Gabor Fischer, Department Head Link: https://www.researchgate.net/job/908942_Assistant_Associate_Professor-Department_of_Pathology Employer: University of Manitoba Location: Winnipeg, Manitoba Sector: Academia Degree required: PhD Conditions: NDG Job posted: April 19th, 2018 Applications close: May 15th, 2018 | University of Manitoba | Winnipeg, Manitoba | PhD | NDG | Apr 19, 2018 |
Director, Therapeutic DevelopmentDirector, Therapeutic Development(Click title to open job details in a new window.)Description: We are currently seeking a new Director of Therapeutic Development to over see the Program of Excellence focused on Neurodegenerative Diseases. Reporting to the Executive Director of the Orphan Disease Center (ODC) and supporting a Program of Excellence, your goal will be to provide international leadership in establishing research agenda in rare disease that are a high priority of the ODC. You will be developing strong partnerships with key stakeholders, including patient advocacy groups, partnering academic institutions and key opinion leaders in relevant diseases by organizing international scientific symposiums related to diseases of interest to the program of excellence, partnering with ODC staff to organize these events. You will have the primary responsibility for creating and executing a strategic plan, to establish clinical development for novel therapeutics. You will seek advisement from all relevant stakeholders, including patient advocacy groups, ODC leadership, and external advisors in initial development of this plan. In executing this plan, you will undoubtedly be required to have extensive interactions with biopharmaceutical industry partners, knowledgeable on the development of novel therapeutics and will require you to travel to biomedical conferences. You will establish working groups within each disease to address research and clinical practice gaps, and focus on filling those gaps to further the development of effective treatments. You will be critical in the success of the program of excellence, providing careful oversight of the research conducted by grant recipients, assuring progress and progression of science towards a biopharmaceutical partnership. It will be essential that you have experience in biopharm to assure these critical links occur between the grant recipients and corporate partners. Joining the ODC offers you with unique opportunity to contribute to revolutionizing the practice of medicine for these under-served patient groups. Link: https://main.hercjobs.org/jobs/10953869/director-therapeutic-develpment-neurodegenerative Employer: University of Pennsylvania School of Medicine Location: Philadelphia, PA Sector: Academia Degree required: Conditions: NDG Job posted: April 18th, 2018 | University of Pennsylvania School of Medicine | Philadelphia, PA | NDG | Apr 18, 2018 | |
Postdoctoral Fellow, Gopal LabPostdoctoral Fellow, Gopal Lab(Click title to open job details in a new window.)Description: Motivated PhD graduates seeking research training in the cell biology of neurodegenerative disease are invited to apply to postdoctoral research position(s) in the Department of Pathology at Yale University. Successful candidates will utilize live cell and super-resolution imaging techniques, mass spectroscopy/CyTOF and biochemistry in primary neurons and mouse models, iPSC-derived neurons, and/or patient tissue samples to define the molecular mechanisms driving assembly, transport, and cellular functions of neuronal ribonucleoprotein (RNP) complexes under physiologic conditions and in neurodegenerative disease. Emphasis will be placed on defining molecular mechanisms relevant to the pathophysiology of age-related inherited and sporadic neurodegenerative diseases, including Alzheimer’s disease and related dementias, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS), with a long-term goal of guiding the development of novel therapies. Recent work has used live cell and super-resolution imaging techniques to study the biophysical properties of neuronal ribonucleoprotein granules and has shown that ALS-linked mutations fundamentally perturb the dynamic properties and transport of neuronal RNP complexes. Successful candidates will be guided to develop independent research careers under the mentorship of Dr. Gopal. Strong written and verbal communication skills, as well as a track record of publications in peer-reviewed journals, are required. Candidates should have prior expertise in cellular and molecular neurobiology, genetics, and the design and characterization of CRISPR and/or transgenic mouse models. Prior experience with iPSC-derived neurons, CRISPR gene-editing techniques, RNA imaging, quantitative analysis of imaging data, and/or characterizing mouse models of neurodegenerative or neurodevelopmental disorders is highly desirable. Interested candidates should forward a cover letter, curriculum vitae, and a 1-2 page description of their research interests, together with the names and contact information of three references via email to: pallavi.gopal@yale.edu Link: https://www.linkedin.com/jobs/view/625914190/ Employer: Yale University School of Medicine Location: New Haven, CT Sector: Academia Degree required: PhD Conditions: ALS Job posted: April 17th, 2018 | Yale University School of Medicine | New Haven, CT | PhD | ALS | Apr 17, 2018 |
Postdoctoral Fellow, Sareen LabPostdoctoral Fellow, Sareen Lab(Click title to open job details in a new window.)Description: Dr. Dhruv Sareen’s independent research laboratory at the Cedars-Sinai Medical Center, Regenerative Medicine Institute focuses on using human iPSC technology to understand the molecular mechanisms underlying neurodevelopmental/degenerative diseases and how obesity is linked to the brain. His laboratory is particularly interested ‘disease-in-a-dish’ modeling for neuromuscular, neurodegenrative and motor neuron diseases including, amyotrophic lateral sclerosis (ALS). They are particularly interested in C9orF72 and other genetic forms of ALS and what are the common elements with sporadic forms of ALS. Using the iPSC platform his lab has developed novel methods for drug screening on patient motoneurons and dissecting mechanisms for motoneuron degeneration. In the context of stem cell modeling of neurodevelopmental (SMA) and neurodegenerative diseases (ALS) Dr. Sareen’s group is particularly interested in the mechanistic insights how specific neural cell types degenerate during the disease processes. They are using OMICS (proteome, transciptome, metabolome) and imaging methodologies to gain mechanistic insights into the mitochondrial and endorplasmic reticulum stress involvement. In addition, by understanding how the cells of the nervous system develop and differentiate we will be able to develop better and safer cells for transplantation and regenerative therapies. Dr. Sareen’s group has extensive experience in pluripotent and neural stem cell research. He has developed and directed a well-renowned human iPS cell core. He has published high-profile manuscripts on human iPSC-based disease modeling in SMA and ALS. Dr. Sareen’s laboratory is searching for a highly-capable Post-doctoral Researcher to join his research group to investigate disease mechanisms in neurodegenerative diseases, especially motor neuron disorders. The incumbent should have experience in in neurobiology, biochemistry, molecular biology and stem cells, including analyzing their genetic and biochemical profiles by OMICS technologies. Bioinformatics (programming in R) knowledge is a plus. By using human iPS cell technology and differentiating into different brain cells as well as other tissues of the body we will investigate brain-linked disease mechanisms to develop assays in patient-derived enural cell types and screen for novel therapeutics. Working independently but in close cooperation and in consultation with the PI and other Research Scientists at RMI, the Post-doctoral Researcher will perform routine and complex laboratory procedures throughout. The Post-doctoral Researcher will be expected to assist the PI in preparation of multiple grant proposals and submission of such proposals. They will also prepare full manuscripts for publication as primary first and co-authors. The researcher will be expected to assist the PI in maintaining institutional IRB/SCRO protocols as well as develop new animal and IACUC protocols. The incumbent will develop, adapt, and implement new research techniques and protocols and will analyze and interpret data. They will participate in presentations as author or co-author on scientific meeting abstracts. Under the direction of Dr. Sareen (PI) the incumbent will help us achieve our research goals by performing the principal duty of using pluripotent and neural stem cell culture techniques to generate neuronal and other tissue differentiation protocols, characterization of the differentiated cells (control vs disease) using techniques such as gene and protein expression, physiological, and phenotypic assessments. The candidate will also be expected to develop and perform differentiation protocols to direct pluripotent stem cells to endoderm, ectoderm and mesoderm lineages. The successful candidate will be responsible for all cell maintenance, expansion and genetic modification using viral vectors or other gene-editing methods. Therefore, experience in stem cell and neurobiology, knowledge of pluripotent/neural cell markers combined with a proven record in stem cell culture techniques is essential. Experience with bioinformatics analysis of RNA-seq and mass spec proteomics data are important. Prior experience in novel genome-editing technologies (CRISPR/Cas9) using pluripotent stem cells is a great asset. Prior experience in high-content compound screening/imaging techniques, handling of the Molecular Devices Image Express Micro system, and a Mass Spectrometer with data analysis are preferred traits. Proficiency in computer algorithm development for automating image-based analysis is also a desirable trait. Link: https://main.hercjobs.org/jobs/10948963/postdoctoral-scientist-ipsc-on-neurodegenerative-disease Employer: Cedars Sinai Location: Los Angeles, CA Sector: Academia Degree required: PhD Conditions: ALS Job posted: April 17th, 2018 | Cedars Sinai | Los Angeles, CA | PhD | ALS | Apr 17, 2018 |
Professor, Structural Biology (W3)Professor, Structural Biology (W3)(Click title to open job details in a new window.)Description: The Institute of Neuropathology, University Medical Center Göttingen (UMG) invites applications for a professorship (W3), structural cell biology commencing as soon as possible. The applicant should be a highly qualified, internationally visible scientist with his or her own scientific profile as well as comprehensive knowledge of and longtime experience in the application of cryo electron microscopy and cryo electron tomography for the structural biology of excitable cells. Profound knowledge of computer-based image analysis and mathematical physical model development must be included in the successful applicant’s profile. Experience in correlating investigations using light microscopy and electron microsopy is also advantageous. Please submit your application until 13rd May using the following link: http://www.med.uni-goettingen.de/de/content/ueberuns/berufungen_onlinebewerbung.html Please send any questions you may have to Berufungen@med.uni-goettingen.de, we will try to answer them. Link: http://www.med.uni-goettingen.de/de/content/ueberuns/berufungen_onlinebewerbung.html Employer: University Medical Center Göttingen Location: Göttingen, Germany Sector: Academia Degree required: Conditions: NDG Job posted: April 17th, 2018 Applications close: May 13th, 2018 | University Medical Center Göttingen | Göttingen, Germany | NDG | Apr 17, 2018 | |
Research AssistantResearch Assistant(Click title to open job details in a new window.)Description: We are seeking a research assistant to produce proteins related to the ALS (Motor Neuron disease), as part of an international project to generate high-quality antibodies for therapeutic research. You will have a degree in biology/biochemistry and proven experience in cloning, expressing and purifying proteins from bacterial and eukaryotic cells. You will be required to adapt or develop procedures for expressing and purifying the target proteins to a high standard of yield and purity. You will be able to work as part of a multidisciplinary team and be well-organised in planning and documenting experiments. The post is full-time and available on a fixed-term contract until 31 December 2020 in the first instance. You will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post. Only applications received before 12.00 noon on 14 May 2018 will be considered. Link: http://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=134505 Employer: University of Oxford Location: Oxford, England Sector: Academia Degree required: Conditions: ALS Job posted: April 17th, 2018 Applications close: May 14th, 2018 | University of Oxford | Oxford, England | ALS | Apr 17, 2018 | |
Postdoctoral FellowPostdoctoral Fellow(Click title to open job details in a new window.)Description: The PostDoc Fellow will participate in the discovery and evaluation of candidate targets affecting motor unit function and subsequent sensory motor performance following stroke, SCI, and/or ALS. The PostDoc Fellow may also be expected to study the effects of various clinical interventions in order to aid the design of rehabilitation strategies targeting specific motor unit properties. *Design, execution and interpretation of experiments for the discovery of critical information in motor unit biology as it relates to the condition of-, or recovery from stroke, SCI and/or ALS. Link: https://ricc-hr.silkroad.com/epostings/index.cfm?fuseaction=app.jobinfo&jobid=179121&company_id=16087&version=1&source=ONLINE&jobOwner=994841&aid=1 Employer: Shirley Ryan Ability Lab Location: Chicago, IL Sector: Academia Degree required: PhD Conditions: ALS Job posted: April 15th, 2018 | Shirley Ryan Ability Lab | Chicago, IL | PhD | ALS | Apr 15, 2018 |
Assistant or Associate ProfessorAssistant or Associate Professor(Click title to open job details in a new window.)Description: The Department of Developmental Biology (www.devbio.pitt.edu) at the University of Pittsburgh School of Medicine is recruiting an outstanding tenure-track or tenured faculty at the Assistant to Associate Professor level. Candidates should have an innovative research program in the area of developmental neurobiology. The use of mouse, zebrafish, and/or stem cell culture or organoid models (iPSC or ES) with strong translational relevance to neurodevelopmental disorders are particularly encouraged to apply. Successful candidates must hold the PhD, MD, or MD/PhD degrees, and have a strong research program with an outstanding publication record. The successful candidate will be housed in new space at the Rangos Research Center of the Children’s Hospital of Pittsburgh with state of the art core facilities, includingFACS facility, vivarium, rodent behavioral core, small animal imaging facility, and others. Link: https://main.hercjobs.org/jobs/10937111/associate-professor Employer: University of PIttsburgh Location: Pittsburgh, PA Sector: Academia Degree required: PhD, MD, or MD/PhD Conditions: NDG Job posted: April 13th, 2018 | University of PIttsburgh | Pittsburgh, PA | PhD, MD, or MD/PhD | NDG | Apr 13, 2018 |
Research AssistantResearch Assistant(Click title to open job details in a new window.)Description: Applications are invited for the post of Research Assistant working on an exciting project which aims to improve the way in which the NHS delivers respiratory therapies, such as non-invasive ventilation (NIV), to patients with motor neurone disease (MND). You will work on Work Packages 2, 3 and 4 of this project. Work Package two involves carrying out a survey to explore current clinical practices and standards relating to the use of NIV in MND in the UK and in similar services to the NHS within Europe. Work Package 3 involves carrying out stakeholder consultations to explore and contextualise the research findings from previous Work Packages and to gain input about how best to translate them into clinical practice. Work Package 4 focuses on creating and testing a practical information toolkit to support the practice of healthcare professionals involved in the respiratory management of MND patients. You will work to closely with clinicians and researchers at University of Sheffield’s Department of Neuroscience Sheffield Institute for Translational Neurosciences, the School of Health and Related Research, the Psychology department and IT specialists. SITraN is in an internationally recognised multidisciplinary group of scientists and clinicians with expertise in translating research into clinical practice in neurological diseases and is a core member of the prestigious NIHR Sheffield Biomedical Research Centre. The salary is Grade 6, £25,728 – £29,799 per annum. Potential to progress to £32,548 per annum. To apply for this position, click here. Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVEODhGQUQzQTVERjE0NTlEOEUmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos# Employer: University of Sheffield Location: Sheffield, England Sector: Academia Degree required: Conditions: ALS Job posted: April 13th, 2018 Applications close: April 25th, 2018 | University of Sheffield | Sheffield, England | ALS | Apr 13, 2018 | |
Postdoctoral Fellow, Sun LabPostdoctoral Fellow, Sun Lab(Click title to open job details in a new window.)Description: Postdoctoral opportunities are available in Dr. Shuying Sun’s laboratory at Johns Hopkins University School of Medicine. The lab will explore the fascinating frontiers of RNA metabolism dysfunction and RNA-targeting therapy in neurodegenerative diseases by combining molecular and cellular approaches, genome editing, proteomic, genomic and screening platforms. The nervous system has extremely complex RNA processing regulation and dysfunction of RNA metabolism has emerged to play crucial roles in multiple neurological diseases. Mutations and pathologies of several RNA-binding proteins are found to be associated with neurodegeneration in both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). An alternative RNA-mediated toxicity arises from microsatellite repeat instability in the human genome. The expanded repeat-containing RNAs could potentially induce neuron toxicity by disrupting protein and RNA homeostasis through various mechanisms. The Sun lab is interested in deciphering the molecular mechanisms of disease pathogenesis and seeks to translate the mechanistic findings to therapeutic target development to advance treatment options against neurodegenerative diseases. We are looking for highly motivated postdoc fellows with solid PhD training in biochemistry, molecular and cellular biology. Experiences with RNA biology, neuroscience or bioinformatics are preferred but not limited to. You will join a strong and highly interactive science community at Johns Hopkins. Interested candidates should provide a cover letter (with statement of research interest and career goals), CV and the contact information for three references to Dr. Shuying Sun at shuying.sun@jhmi.edu. Please visit our lab website at http://labs.pathology.jhu.edu/sun/ for additional information. Link: https://www.nature.com/naturejobs/science/jobs/641473-postdoctoral-positions-on-rna-biology-and-neurodegenerative-disease Employer: Johns Hopkins University School of Medicine Location: Baltimore, MD Sector: Academia Degree required: PhD Conditions: ALS, FTD Job posted: April 10th, 2018 | Johns Hopkins University School of Medicine | Baltimore, MD | PhD | ALS, FTD | Apr 10, 2018 |
Research AssociateResearch Associate(Click title to open job details in a new window.)Description: The Center for Genomics of Neurodegenerative Disease at the New York Genome Center is looking for a well-organized, methodical, and highly motivated Research Associate. This is an exciting opportunity to become part of a dynamic group that is investigating the interactions between motor neurons and glial cells in ALS pathology using hiPSC cell-based models combined with next generation sequencing and CRISPR technology. Our particular focus is to examine the transcriptional, translational, and functional impact of causative ALS mutations in a cell type specific manner. The individual will interface with the Director and key scientific staff to assume responsibility for hiPSC culture, differentiation, functional assays, and RNA harvesting for NGS. The Research Associate will be part of an interdisciplinary team working in a fast-paced environment. Responsibilities Include, But Are Not Limited To Link: https://nygenome-openhire.silkroad.com/epostings/index.cfm?fuseaction=app.dspjob&jobid=265&company_id=17105&version=1&jobBoardId=3347 Employer: New York Genome Center Location: New York, NY Sector: Academia Degree required: BS or MS Conditions: ALS Job posted: April 9th, 2018 | New York Genome Center | New York, NY | BS or MS | ALS | Apr 09, 2018 |
Assistant Professor of NeurologyAssistant Professor of Neurology(Click title to open job details in a new window.)Description: The Center of Image Acquisition (CIA) at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute seeks a qualified applicant for an Assistant Professor (tenure track) position in the USC Department of Neurology. The CIA serves as central resource for the development and application of advanced imaging for all neuroimaging research at the Keck School of Medicine of USC. The CIA will interact and collaborate with many departments at the Health Sciences Campus and the University Park Campus conducting research in methodology and its application in the study of normal, neurological and psychiatric cohorts. The ideal candidate should have a Ph.D. in Biophysics, Biomedical Engineering, or a related field, and have 2-3 years of postdoctoral training in the field of MRI physics and its applications in neuroscience. The candidate is expected to develop innovative MRI techniques, in particular noninvasive blood flow and perfusion imaging. The main duties of this position include the development of an independent and/or collaborative research program and participation in multidisciplinary research applying novel MRI imaging techniques for assessing and diagnosing neurovascular and neurodegenerative diseases. Experience on pulse sequence programming, particularly on Siemens platform is highly desirable. Link: https://jobs.sciencecareers.org/job/477691/assistant-professor-of-neurology-tenure-track-/ Employer: University of Southern California Location: Los Angeles, CA Sector: Academia Degree required: PhD Conditions: NDG Job posted: April 5th, 2018 | University of Southern California | Los Angeles, CA | PhD | NDG | Apr 05, 2018 |
Assistant Professor, NeurologyAssistant Professor, Neurology(Click title to open job details in a new window.)Description: The USC Stevens Neuroimaging and Informatics Institute (INI) seeks highly-qualified applicants for the position of Assistant Professor (tenure-track). The successful applicant will have a minimum 5+ years experience (post doctoral degree) in imaging in aging and neurodegenerative diseases. A particular emphasis on functional and structural connectivity in Alzheimer’s disease is desired. The candidate should have specific interest in mechanistic processes of aging include neuroinflammation, and/or genetics. A strong foundation in understanding the role of imaging, genetics, and clinical phenotypes in characterizing age- and disease-related phenomena is desired. The candidate should have a PhD in Neuroscience, Psychology, or other related disciplines; a strong foundation in neuroimaging and 5+ years post-PhD research experience with a successful publication record and teaching experience is required. The applicant must demonstrate an ability to work with a highly collaborative and multidisciplinary team. Further, the applicant must have demonstrated a strong track record of obtaining independent funding to support a research program. To apply, include a cover letter, CV, salary history and list of references. Include in your cover letter where you saw this posting or how you learned of this opening. Link: https://jobs.sciencecareers.org/job/477692/assistant-professor-of-neurology-tenure-track-/ Employer: University of Southern California Location: Los Angeles, CA Sector: Academia Degree required: PhD Conditions: NDG Job posted: April 5th, 2018 | University of Southern California | Los Angeles, CA | PhD | NDG | Apr 05, 2018 |
Postdoctoral Fellow, Deleidi LabPostdoctoral Fellow, Deleidi Lab(Click title to open job details in a new window.)Description: A position for a talented and highly motivated Postdoctoral Researcher is available within the scientific team “Mitochondria and Inflammation in Neurodegeneration” led by Michela Deleidi in Tübingen. The research focus of our group is on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in neurodegenerative diseases. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson’s disease. Our aim is to understand, at the molecular level, how immune responses within or outside the brain contribute to neurodegeneration. Our final goal is to translate fundamental discoveries to better preventive and therapeutic approaches for neurodegenerative diseases. Please see our website for more information about our research: https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/deleidi/research-areasfocus/. The successful candidate will conduct a research project aimed at further elucidating the link between metabolic and energetic defects and immune homeostasis in Parkinson’s disease. The project will involve close collaborations with international partners. For this project, a combination of in-vitro models (human cell lines including induced pluripotent stem cells) and in-vivo models (mouse models) will be used as well as a variety of approaches including use of human induced pluripotent stem cells (2D, 3D and brain organoids), CRISPR-Cas9 genome editing, flow cytometry, microscopy, RNA-seq and metabolomics, and use of in-vivo models (with external collaborators). You will conduct your own research project, collaborating with PhD and Postdoctoral Researchers as well as international partners. The goal is to publish our work in outstanding scientific journals. Link: https://www.nature.com/naturejobs/science/jobs/641215-postdoctoral-researcher-f-m Employer: German Center for Neurodegenerative Diseases Location: Tübingen, Germany Sector: Academia Degree required: PhD Conditions: NDG Job posted: April 5th, 2018 | German Center for Neurodegenerative Diseases | Tübingen, Germany | PhD | NDG | Apr 05, 2018 |
Postdoctoral Fellow, Dupuis LabPostdoctoral Fellow, Dupuis Lab(Click title to open job details in a new window.)Description: A 3-year post-doctoral position is available in Inserm U1118, Strasbourg, France under the supervision of Dr Luc DUPUIS. The successful candidate will investigate the relationships between TAU, FUS and TDP-43 in the development of amyotrophic lateral sclerosis and fronto-temporal dementia, two related neurodegenerative diseases currently untractable. This will be done by combining mouse genetics and behaviour with molecular biology techniques based on next generation sequencing and pathological studies in patient tissues. An experience in NGS techniques such as RNAseq and/or CLIPseq will be highly appreciated. The position is secured for 3 years, and funded by the ANR. Applications including a detailed CV and contact of at leat two previous supervisors, should be sent to Dr Luc Dupuis (ldupuis@unistra.fr). Recent publications from the laboratory: Vercruysse P, et al. Brain. 2016, Apr;139(Pt 4):1106-22. Employer: Inserm U1118 Location: Strasbourg, France Sector: Academia Degree required: PhD Conditions: ALS, FTD Job posted: April 4th, 2018 | Inserm U1118 | Strasbourg, France | PhD | ALS, FTD | Apr 04, 2018 |
Research Associate II, Svendsen LabResearch Associate II, Svendsen Lab(Click title to open job details in a new window.)Description: The Svendsen Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for personnel to join our dynamic group. The ideal incumbent should have experience in managing and analysis of large datasets using programming languages such as Python and R, and an interest in working hands on with stem cells and organ-on-chip technology with a focus on research in neurodegenerative diseases (Brain-on-Chip). Ideal candidate will also have experience in machine learning approaches for use in automation of laboratory equipment and analysis of complex bioinformatic datasets. Working with the P1 and scientists, the Research Associate II (RA11) performs a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research, including the Brain-on-Chip program. RAII is responsible for the generation and curation of acquired data, implementation of analysis programs, and generation of scripts to assists in laboratory activities and research aims. RAH is responsible for general laboratory activities including maintenance of reagents, ordering and stocking of supplies. RA11 keeps accurate and detailed records of experiments and results. RAH assists in the operation of specialized equipment and machinery, including the culture of human stem cell derived tissues. Observes safety standards and procedures. This position may include supervisory responsibilities. Daily Duties will include the following: – Performs a variety of routine laboratory tasks and procedures. – Works with laboratory staff to develop and implement analysis frameworks for use in biomarker and therapeutic target discovery – Keeps accurate and detailed project records of experiments and results. – Maintains lab equipment and related records. – Transports, processes and logs samples. – Maintains computer database with relevant information – implements scripts for the analysis of complex imaging and multi-omic analysis datasets. – Performs lab maintenance duties, including glassware cleaning and sterilization, – Maintains stocks of general lab materials, and places orders for lab equipment and supplies. – Assists new students and fellows at the laboratory. – Assists in the operation of specialized equipment and machinery. – Observes and complies with safety standards arid procedures. – Histology and Microscopy – Sectioning of tissue specimens – Staining of tissue specimens to include special stains and INC. Additional Information: Scheduling flexibility including evening, weekend and holiday rotation commitment is required. Travel may be required. Link: https://main.hercjobs.org/jobs/10908722/research-associate-ii-stem-cells Employer: Cedars-Sinai Location: Los Angeles, CA Sector: Academia Degree required: BA or BS Conditions: ALS Job posted: April 4th, 2018 | Cedars-Sinai | Los Angeles, CA | BA or BS | ALS | Apr 04, 2018 |
Research Associate, McDermott LabResearch Associate, McDermott Lab(Click title to open job details in a new window.)Description: We are seeking an outstanding early-career researcher with the potential to become a leader in the field of mixed-methods health services research. You will join the research group of Professor Christopher McDermott at the Sheffield Institute for Translational Neuroscience (SITraN) to work on clinical research projects focusing on the supportive and symptomatic management of patients with motor neurone disease (MND) and other neurodegenerative disorders. This post provides an excellent opportunity to undertake high quality research within a stimulating multi-disciplinary context. You will work directly with a team of clinicians and researchers on HighCALS, a National Institute for Health (NIHR) funded research programme, with the aim to develop and evaluate a complex intervention to achieve a high calorie diet for people with Amyotrophic Lateral Sclerosis (ALS). HighCALS is a collaboration of co-investigators from the Sheffield Institute for Translational Neuroscience (SITraN), the School of Health and Related Research (ScHARR) and the Department of Psychology at the University of Sheffield; and the School of Food Science and Nutrition at the University of Leeds. You will have a Masters or PhD in a relevant discipline or equivalent experience. This post is full time, fixed term for 2 years. The salary is Grade 7, Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVFODhDQ0QzOTQ3RTQ3MzE3NEYmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos# Employer: University of Sheffield Location: Sheffield, England Sector: Academia Degree required: PhD Conditions: ALS Job posted: April 4th, 2018 Applications close: May 2nd, 2018 | University of Sheffield | Sheffield, England | PhD | ALS | Apr 04, 2018 |
Chair, Department of Translational NeurosciencesChair, Department of Translational Neurosciences(Click title to open job details in a new window.)Description: The University of Arizona College of Medicine – Phoenix is seeking an inaugural Chair for its new Department of Translational Neurosciences (TNS). TNS will be a novel medical school department, one that actively bridges basic science and clinical medicine through innovative collaborative research programs. The Chair will have the opportunity to create the overarching vision and, through strategic leadership, to build a center of translational neuroscience excellence. The Department Chair will have resources to recruit TNS faculty who will enhance our University of Arizona Health Sciences (UAHS) scientific community. We seek a visionary leader with expertise in molecular, cellular, or genetic approaches to neuroscience whose research is motivated by the challenges of nervous system disorders and directed toward advancing clinical care and improving human health in the foreseeable future. Of particular interest for the Chair of TNS position are applicants with any of the following: *Research portfolio focused on molecular, cellular, and/or genetic approaches to neuroscience. Examples of foci include: Neurodevelopmental disorders, Neuropsychiatric disorders, Disorders of the aging brain Link: https://uacareers.com/postings/26190 Employer: University of Arizona College of Medicine Location: Phoenix, AZ Sector: Academia Degree required: PhD and/or MD Conditions: NDG Job posted: April 2nd, 2018 | University of Arizona College of Medicine | Phoenix, AZ | PhD and/or MD | NDG | Apr 02, 2018 |
Postdoctoral Fellow, Durham LabPostdoctoral Fellow, Durham Lab(Click title to open job details in a new window.)Description: A postdoctoral position in ALS research is available in the laboratory of Dr. Heather Durham in the Rare Neurological Diseases Group at the Montreal Neurological Institute, McGill University, Montreal QC Canada. The project involves investigating the role of chromatin remodeling as a convergent mechanism in ALS and in neuronal stress responses (see https://www.ncbi.nlm.nih.gov/pubmed/28973294). The work would include investigation of epigenetic mechanisms in primary culture models, mouse models and post-mortem tissue as well as participation in a drug study in mouse and tissue culture models of ALS. This multidisciplinary project is funded by MDA and by an ALS Canada-Brain Canada Hudson Translational Team Grant involving collaborators with complementary expertise at other Canadian universities. Applicants are expected to have a PhD in a relevant biomedical field; to be able to work independently as well as a team member, and to bring a passionate interest in working together to understand the pathogenesis of ALS and to find effective treatment. Expertise in epigenetics, stress responses, molecular biology, biochemical assays, mouse models and tissue processing/histochemical techniques are examples of useful experience to complement our team. To apply for this position, contact Dr Heather Durham. The Montreal Neurological Institute and Hospital – The Neuro (http://www.mcgill.ca/neuro/), is a world-leading destination for brain research and advanced patient care. Since its founding in 1934 by renowned neurosurgeon Dr. Wilder Penfield, The Neuro has grown to be the largest specialized neuroscience research and clinical centre in Canada, and one of the largest in the world. The seamless integration of research, patient care, and training. The Neuro is home to one of the leading ALS clinics and clinical research units, providing interaction between ALS scientists, clinicians and patients.
Employer: McGill University Location: Montreal, Canada Sector: Academia Degree required: PhD Conditions: ALS Job posted: March 30th, 2018 | McGill University | Montreal, Canada | PhD | ALS | Mar 30, 2018 |
Group Leader, Big Data NeuroscienceGroup Leader, Big Data Neuroscience(Click title to open job details in a new window.)Description: Can you develop a productive and innovative research program and establish an independent research group through a combination of core funding and extramural funding? Can you complement the research program of the NIN by working in close collaboration with other research groups at the institute? And do you have a clear vision on how to approach the current challenges in one of the three neuroscience research fields described below? Then this job may be for you. There is an increasing global collaboration to collect, pool and distribute huge datasets on human genetics, gene expression and brain imaging in order to understand the neurobiological underpinnings of a wide variety of complex traits and phenotypes in health and disease. To bridge these opportunities with current research topics and facilities like the Brain Bank and 7T MRI at the NIN, we are seeking an outstanding scientist who is leading in the innovative use of datasets like the UKBiobank, 23andMe and ENIGMA. The ideal candidate has mathematical, computational, statistical, neurobiological and cognitive-behavioral expertise, as well as technological skills for cluster computing. Applications should be submitted via the online application form, before 30 April 2018:
The pre-selection will be done by a gender-balanced panel of peers from the institute. For further information you can look at our website: nin.nl or contact Pieter Roelfsema p.roelfsema@nin.knaw.nl, General Director, Ronald van der Neut r.van.der.neut@nin.knaw.nl, Managing director, or Dorien Bisselink d.bisselink@nin.knaw.nl, head human resources department. Link: https://www.academictransfer.com/employer/KNAW/vacancy/46229/lang/en/ Employer: Netherlands Institute for Neuroscience Location: Amsterdam, Netherlands Sector: Academia Degree required: PhD Conditions: NDG Job posted: March 28th, 2018 Applications close: April 29th, 2018 | Netherlands Institute for Neuroscience | Amsterdam, Netherlands | PhD | NDG | Mar 28, 2018 |
Postdoctoral Fellow, Van Damme LabPostdoctoral Fellow, Van Damme Lab(Click title to open job details in a new window.)Description: The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains. In addition, the laboratory is one of the research groups of the VIB Center for Brain & Disease Research (CBD) at KU Leuven/ Campus Gasthuisberg focusing on Neuroscience. There are 17 research groups within the CBD with a total employment of 300 researchers (38 different nationalities). The Laboratory focusses on clinical and fundamental research into the prevention, heredity, the pathogenesis and treatment of neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Charcot-Marie-Tooth Disease (CMT) and stroke. We are looking for a highly motivated doctoral researcher with interest in neurodegeneration and experience in progranulin biology and/or iPSC technology. Motivated candidates with a strong commitment to basic research are invited to apply. The research project, under supervision of principal investigator Philip Van Damme, will focus on the neurodegenerative disorders ALS and FTD and will involve in vitro techniques, validation of neuroprotective compounds, iPSCs and small animal models. Applications should be submitted through the VIB website. Please complete the online application procedure and include a CV, a list of publications if applicable, a summary of past research and the contact information of 2 to 3 referees. The best-ranked candidates will be invited for an interview. For additional information concerning this job offer, please contact Lien Houbrechts. Link: https://www.nature.com/naturejobs/science/jobs/640803-phd-position-on-ipsc-models-in-neurodegeneration-als-and-frontotemporal-dementia Employer: VIB Location: Leuven, Belgium Sector: Academia Degree required: PhD Conditions: ALS, FTD Job posted: March 27th, 2018 Applications close: May 27th, 2018 | VIB | Leuven, Belgium | PhD | ALS, FTD | Mar 27, 2018 |
Neuropathologist, Physician Scientist, Neurodegenerative DiseaseNeuropathologist, Physician Scientist, Neurodegenerative Disease(Click title to open job details in a new window.)Description: The Department of Pathology at Northwestern University Feinberg School of Medicine seeks a full-time Assistant Professor, Associate Professor or Professor on the tenure track. Qualified candidates will be physician-scientists MD or MD, PhD, and be Board-certified in Neuropathology. They are expected to develop a federally funded, independent research program in the area of neurodegeneration and engage in collaborations with other researchers who study neurodegenerative diseases throughout Northwestern University. Service responsibilities include participation in diagnostic neuropathology, which could include surgical, autopsy or neurodegenerative neuropathology, depending on the applicant’s career goals. There will be ample opportunities for mentoring and teaching graduate students, medical students and resident/fellows, as well as for service on department, school or university committees. Qualified candidates will become a leader of the Neuropathology Core of the federally funded Cognitive Neurology and Alzheimer’s Disease Center. The environment for hypothesis driven basic research, and for translational and collaborative research at Northwestern University and the Northwestern Memorial Hospital is outstanding. Interested applicants should submit a letter of interest, curriculum vitae, and names of three to five references via Northwestern University’s Faculty Recruiting Website. Daniel J. Brat MD, PhD Link: https://jobs.sciencecareers.org/job/477324/neurodegenerative-neuropathologist-physician-scientist/ Employer: Northwestern University Location: Chicago, IL Sector: Academia Degree required: MD or MD/PhD, and Board-certified in Neuropathology Conditions: NDG Job posted: March 26th, 2018 | Northwestern University | Chicago, IL | MD or MD/PhD, and Board-certified in Neuropathology | NDG | Mar 26, 2018 |
Assistant, Associate or Full Professor, Molecular Pharmacology & PhysiologyAssistant, Associate or Full Professor, Molecular Pharmacology & Physiology(Click title to open job details in a new window.)Description: The Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine invites applications for tenure-track faculty positions at the Assistant/Associate/Full Professor levels. A doctoral degree in medical or biomedical sciences is required. Applicants must demonstrate a strong record of academic accomplishments with NIH-supported research programs. Expertise in neuroscience, cardiovascular, splanchnic organ system, metabolism and inflammation/immunology research areas is preferred, with an emphasis on the study of molecular, cellular and systemic mechanisms. Applicants must also demonstrate a history of medical school teaching excellence and are expected to have outstanding verbal communication skills. Candidates should send their curriculum vitae that include previous and current research funding, teaching experience, a statement of research plans, and the names/contact information of three references in a single PDF to: Victoria Mothershed at vmothershed@health.usf.edu. Link: https://jobs.sciencecareers.org/job/477224/assistant-associate-full-professor/ Employer: University of South Florida Location: Tampa, FL Sector: Academia Degree required: PhD Conditions: NDG Job posted: March 22nd, 2018 | University of South Florida | Tampa, FL | PhD | NDG | Mar 22, 2018 |
Postdoctoral Fellow, Mueller LabPostdoctoral Fellow, Mueller Lab(Click title to open job details in a new window.)Description: We seek a talented and motivated postdoc to join the laboratory of Dr Christian Mueller in the Horae Gene Therapy Center at the University of Massachusetts Medical School. Our dynamic and collaborative research environment at UMMS includes world renowned clinicians and scientists. Additionally, our location close to Boston supports many collaborations with academic and industrial research groups. Open positions include: CNS Lead. Responsible for advancing the lab’s preclinical programs for CNS diseases. Lead indications are SOD1, C9orf72-linked amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD). Projects will include early stage research on genome editing for ALS, an IND-enabling study in non-human primates for a gene therapy candidate for ALS, and an IND-enabling study in non-human primates for a gene therapy candidate for HD. Required Qualifications: Required skills: For more information on the Mueller Lab for Gene Therapy we invite you to visit our website: www.umassmed.edu/muellerlab Link: https://www.indeed.com/viewjob?jk=529c3289cc30c894&tk=1c9a9vpkj0keo44e&from=serp&vjs=3 Employer: University of Massachusetts Medical Center Location: Worcester, MA Sector: Academia Degree required: PhD Conditions: ALS Job posted: March 21st, 2018 | University of Massachusetts Medical Center | Worcester, MA | PhD | ALS | Mar 21, 2018 |
Postdoctoral Fellow, Kalra LabPostdoctoral Fellow, Kalra Lab(Click title to open job details in a new window.)Description: Postdoctoral positions are available in the ALS Neuroimaging Research Unit at the University of Alberta. The mission of the lab is to further our understanding of the biology of amyotrophic lateral sclerosis (ALS) using advanced MRI methods. The lab is directed by Dr. Sanjay Kalra, a neurologist and researcher, and the director of the Canadian ALS Neuroimaging Consortium (CALSNIC). Areas of investigation include 1) Modeling of multimodal MRI data to quantify and characterize cerebral degeneration, 2) Development of novel image analysis methods as potential biomarkers, and 3) Ex-vivo validation of MRI metrics. Qualifications: • A PhD or equivalent in a relevant discipline such as computer science, biomedical or electrical engineering, medical physics, or neuroscience • Experience with image analysis methods and tools (MATLAB, Unix, FSL, etc) • Familiarity with DTI, structural and functional connectivity, magnetic resonance spectroscopy, cortical thickness estimation, or ex-vivo imaging is an asset • Highly motivated and able to work collaboratively in a multidisciplinary environment • Good written and verbal communication skills in English Interested individuals should forward a CV and list of references with their email addresses to: Sanjay Kalra, MD FRCPC Professor, Department of Medicine University of Alberta sanjay.kalra@ualberta.ca Link: http://www.alsresearchforum.org/wp-content/uploads/PDF-Kalra.pdf Employer: University of Alberta Location: Alberta, Canada Sector: Academia Degree required: PhD Conditions: ALS Job posted: March 19th, 2018 | University of Alberta | Alberta, Canada | PhD | ALS | Mar 19, 2018 |
Senior Research InvestigatorSenior Research Investigator(Click title to open job details in a new window.)Description: The Gene Therapy Program (GTP) and Orphan Disease Center (ODC) are entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases. Our R&D organization has a translational infrastructure that includes: technology discovery, specialized immunology assays operating under GLP, a Vector Core/Manufacturing unit that conducts GMP comparable work, and a large non-clinical program for animal testing under GLP including large NHP and rodent vivaria. We are currently looking for Senior Research Investigator (SRI), Translational Research, to work in one of several therapeutic areas such as motor neuron, neurodegenerative, and/or therapeutic antibodies. This position offers the opportunity to interface broadly internally & externally with diverse functional areas. Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures. Candidate must thrive in a team environment, have excellent written and oral communication skills, ability to prioritize in a fast-paced environment, and proficiency with standard methods of data analyses Link: https://www.linkedin.com/jobs/view/308194466/ Employer: University of Pennsylvania Location: Philadelphia, PA Sector: Academia Degree required: PhD Conditions: ALS Job posted: March 19th, 2018 | University of Pennsylvania | Philadelphia, PA | PhD | ALS | Mar 19, 2018 |
Industry
| Job Title | Employer | Location | Degree | Conditions | Date Posted ▾ |
|---|---|---|---|---|---|
Director, Antibody DiscoveryDirector, Antibody Discovery(Click title to open job details in a new window.)Description: Voyager is seeking a highly motivated scientist and leader with extensive experience in therapeutic antibody discovery and development to contribute to our research team and build the Antibody Platform at the company. This individual will build and lead a platform effort on antibody discovery and engineering including but not limited to AAV-vectorized antibodies, integrating both internal and external resources. Incumbent will also play an important role in business development opportunities and ongoing and future partnerships. The candidate should have substantial working familiarity and demonstrated success with state-of-the-art approaches for generating, selecting, humanizing and optimizing human antibodies and antibody fragments against targets of interest. These approaches include tools and systems such as transgenic mouse strains that produce human antibodies, high throughput hybridoma and B-cell cloning from immunized animals and from human samples, and display technologies for affinity maturation. Responsibilities will include the development of a strategy and implementation of plans for rapid advancement of the vectorized antibody platform, and oversight of a group responsible for activities that include hybridoma screening, antibody gene cloning and sequencing, recombinant antibody expression, antibody humanization, lead antibody identification, antibody optimization including affinity maturation, and antibody characterization. This is an ideal position for an individual who is energetic and thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech company environment. This role is located in Cambridge, MA. Link: https://www.linkedin.com/jobs/view/618406811/ Employer: Voyager Therapeutics Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: May 2nd, 2018 | Voyager Therapeutics | Cambridge, MA | PhD | NDG | May 02, 2018 |
Postdoctoral FellowPostdoctoral Fellow(Click title to open job details in a new window.)Description: We are seeking a highly motivated postdoctoral associate interested in proteinopathy research in the context of neurodegenerative diseases. The successful candidate will be responsible for developing in vitro models to understand underlying mechanisms of pathogenic protein inclusion formation in the brain. The ideal candidate should have excellent communication and writing skills and the ability to work well in a multidisciplinary team. The candidate will periodically present his/her results and will prepare manuscripts for publication of findings in a peer-reviewed journal. Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&partnerid=13617&siteid=5260&jobId=2555665 Employer: Novartis Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: May 2nd, 2018 | Novartis | Cambridge, MA | PhD | NDG | May 02, 2018 |
Senior Scientist, Analytical DevelopmentSenior Scientist, Analytical Development(Click title to open job details in a new window.)Description: Voyager is seeking a highly motivated scientist to contribute to the Analytical Development group. The qualified candidate will participate in development, qualification, and transfer of new state-of-the-art analytical methods to be used for characterization and release of Voyager’s products. This role is currently an individual contributor but may expand to having direct reports in the future. This position is located in Cambridge, MA. Primary responsibilities include, but are not limited to, the following: *Develop analytical methodologies and strategies needed to progress products in the pipeline including method development, process support, formulation and stability support, product characterization and method qualifications Link: https://www.linkedin.com/jobs/view/671598488/ Employer: Voyager Therapeutics Location: Cambridge, MA Sector: Industry Degree required: PhD or MS Conditions: ALS Job posted: April 27th, 2018 | Voyager Therapeutics | Cambridge, MA | PhD or MS | ALS | Apr 27, 2018 |
Senior ScientistSenior Scientist(Click title to open job details in a new window.)Description: Voyager Therapeutics is developing recombinant adeno-associated virus (rAAV) vectors for treating neurological diseases. Developing robust and reliable vector production processes is central for establishing successful gene therapy applications. Voyager is seeking a highly motivated Senior Scientist and/or Engineer to join the Process Development Group with a focus on upstream production. The qualified candidate will be a leader within the group with a strong background and expertise in cell culture manufacturing of biologics. Primary responsibilities will include carrying out upstream process development activities for the manufacture of pre-clinical and cGMP grade rAAV products, participating in and leading internal productions, writing appropriate documents and carrying out technology transfer to assorted CMOs, and finally participating in cGMP manufacture person in plant activities. The ability to independently organize and design experiments, analyze data and report the results of their and other’s work in a concise and well documented manner, and to take the initiative to successfully drive Voyager’s projects and manufacturing process are all important aspects of the position. Ref# 18TO-CM002 To apply, email careers@voyagertherapeutics.com Link: http://www.voyagertherapeutics.com/join-our-team/careers/ Employer: Voyager Therapeutics Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: ALS Job posted: April 24th, 2018 | Voyager Therapeutics | Cambridge, MA | PhD | ALS | Apr 24, 2018 |
Staff Scientist, Medicinal ChemistryStaff Scientist, Medicinal Chemistry(Click title to open job details in a new window.)Description: This lab-based chemist will be a key part of an interdisciplinary team of scientists and will be involved in the design, synthesis, purification, and characterization of novel drugs in the areas of neurodegenerative disease. In this dynamic team focused role, the qualified candidate will also be expected to manage and run the chemistry laboratory, and act as a mentor for junior chemists as needed. Responsibilities include: *Design, synthesis, purification, and characterization of novel drugs in the areas of neurodegenerative disease Link: http://www.yumanity.com/careers/ Employer: Yumanity Therapeutics Location: Cambridge, MA Sector: Industry Degree required: BS or MS Conditions: NDG Job posted: April 20th, 2018 | Yumanity Therapeutics | Cambridge, MA | BS or MS | NDG | Apr 20, 2018 |
Senior Scientist, NeuroscienceSenior Scientist, Neuroscience(Click title to open job details in a new window.)Description: The Merck Early Discovery Neuroscience team is seeking a passionate, research focused and technically skilled in-vitro scientist with strong molecular, cellular and biochemistry expertise in neurodegenerative diseases to join our Boston-based research community. The high-level goal of the group is to effectively advance de novo discoveries from within the laboratory toward medicines to treat neurodegenerative diseases. The concentration of the group is centered on understanding the key determinants of microglia that impact their functional responses to neurodegenerative disease states. Mainly, how do genetic mutations in selected neuroimmune genes confer neurodegenerative susceptibility and by what common or unique mechanisms? By generating and characterizing transgenic models and developing cell-based systems, the team aims to gain insights into causal disease pathophysiology informed by human genetics using combinations of molecular and functional profiling technologies. Target, pathway and functional insights are pressure-tested with pharmacological, biologic and genetic experimental tools to validate insights and mechanistic hypotheses. A core part of the group mission and responsibility of the Senior Scientist is to establish, optimize and transfer insights and assays to enable target and pathway screening. To that goal, candidates with extensive expertise in cellular and molecular neuroscience with de novo assay development experience are encouraged to apply. Link: https://jobs.merck.com/job/Boston-Senior-Scientist-Discovery-Neuroscience-MA-02108/471840600/ Employer: Merck Location: Boston, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: April 19th, 2018 | Merck | Boston, MA | PhD | NDG | Apr 19, 2018 |
Senior Research Associate, NeurobiologySenior Research Associate, Neurobiology(Click title to open job details in a new window.)Description: Verge Genomics is seeking a Research Associate or Sr. Research Associate to join the Neurobiology Research and Drug Discovery team and contribute to innovative research in finding therapies to treat CNS diseases. This candidate will bring pharmaceutical industry experience to conduct in vivo and in vitro research in our SF Bay Area laboratories and join team meetings at Verge Genomics headquarters in SF. The qualified candidate will be highly motivated, interactive and creative with ability to work across functions and projects. The candidate is responsible for contributing to the execution of target validation and evaluation of novel drug candidates for neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. The ideal candidate will have working knowledge of CNS disease and or mechanisms with existing and experimental therapeutic approaches. A keen ability to identify efficient solutions to laboratory problems and working knowledge with statistical analysis are essential. This position reports to the Director of Drug Discovery. Link: https://www.linkedin.com/jobs/view/622106278/ Employer: Verge Genomics Location: San Francisco, CA Sector: Industry Degree required: BS or MS Conditions: ALS Job posted: April 15th, 2018 | Verge Genomics | San Francisco, CA | BS or MS | ALS | Apr 15, 2018 |
Associate ScientistAssociate Scientist(Click title to open job details in a new window.)Description: Yumanity is seeking an associate scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based and requires experimental skills in human stem cell culture, including experience differentiating patient and control-derived progenitor cells into various central nervous system cells. This position will report to a Senior Scientist in Discovery Biology and will collaborate across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry. Responsibilities include: Link: http://www.yumanity.com/careers/ Employer: Yumanity Therapeutics Location: Cambridge, MA Sector: Industry Degree required: BS or MS Conditions: NDG Job posted: April 13th, 2018 | Yumanity Therapeutics | Cambridge, MA | BS or MS | NDG | Apr 13, 2018 |
Principal Scientist, Blood-Brain Barrier (BBB) Transport TechnologiesPrincipal Scientist, Blood-Brain Barrier (BBB) Transport Technologies(Click title to open job details in a new window.)Description: We are seeking an experienced scientist to join Biogen’s Biologics Drug Discovery Team, and contribute to our mission to design, optimize, and develop important protein therapeutics to improve the lives of patients with neurodegenerative disease. In this role, you will jointly lead a cross-functional effort to identify and validate novel methods for enhancing delivery of protein biologics to the central nervous system (CNS). Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=805613#jobDetails=805613_5140 Employer: Biogen Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: April 13th, 2018 | Biogen | Cambridge, MA | PhD | NDG | Apr 13, 2018 |
Scientist I, Analytical Development (Small Molecule + ASO)Scientist I, Analytical Development (Small Molecule + ASO)(Click title to open job details in a new window.)Description: The individual will develop, implement, and qualify innovative analytical solutions for the characterization and testing of ASOs and pharmaceuticals (both off-line and on-line). This work will support process and formulation development and will drive the control strategy. Key areas of focus will be in enhanced impurity monitoring, simple and specific identity testing, and evaluating novel formulations. The primary methods are HPLC/UPLC, MS, and spectroscopy, but the use of other methods is required and should be explored. The work requires cross-functional interactions and the ability to work independently and creatively to influence stakeholders across the development organization. Excellent technical skills, the ability to think outside of the box, and the ability to drive experiments from proof of concept to implementation are required. The selected individual should be able to clearly communicate their results and accomplishments to a broad audience at team meetings and in written reports. Strong self-motivation and drive to make impactful contributions in a fast-paced environment is critical. Qualifications •In-depth knowledge of separation sciences, including (U)HPLC, GC, RP, IC, AEX, and chiral chromatography, and mass spectrometry with extensive laboratory experiences Education Ph.D. (preferred) in analytical chemistry, chemistry, pharmaceutical sciences, or related discipline with a minimum of 0-3 years experience OR MS Degree with a minimum of 5 years experience. Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=806754#jobDetails=806754_5140 Employer: Biogen Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: April 13th, 2018 | Biogen | Cambridge, MA | PhD | NDG | Apr 13, 2018 |
Senior Research Associate, NeuroscienceSenior Research Associate, Neuroscience(Click title to open job details in a new window.)Description: Voyager is seeking a highly motivated biologist to contribute to our research team at our facility in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in in vitro and in vivoexperimental methods, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. The individual will work in the laboratory and be responsible for experimental execution, and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. We are looking for extensive prior hands-on in with techniques such as cell culture, in vitro assay development and execution, CNS tissue preparation, qRT-PCR, western, and ELISA. This role is located in Cambridge, MA and reports to a Principal Research Scientist. Requirements
Strongly Preferred
Link: https://www.linkedin.com/jobs/view/597107321/ Employer: Voyager Therapeutics Location: Cambridge, MA Sector: Industry Degree required: BS or MS Conditions: NDG Job posted: April 5th, 2018 | Voyager Therapeutics | Cambridge, MA | BS or MS | NDG | Apr 05, 2018 |
Scientist I, BiomarkersScientist I, Biomarkers(Click title to open job details in a new window.)Description: The Discovery and Early Development Biomarkers group, part of Biogen’s Research and Early Development department is seeking a highly motivated scientist to join a dynamic team engaged in the discovery and progression of novel biomarkers for neurodegenerative diseases. Responsibilities include executing experiments to identify, evaluate, and characterize relevant fluid biomarkers that will provide useful pharmacodynamic and efficacy endpoints in either preclinical or clinical settings. The successful candidate will be capable of multitasking and effective planning to consistently meet deadlines. Effective communication and collaboration are crucial. Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=805617#jobDetails=805617_5140 Employer: Biogen Location: Cambridge, MA Sector: Industry Degree required: PhD Conditions: NDG Job posted: March 30th, 2018 | Biogen | Cambridge, MA | PhD | NDG | Mar 30, 2018 |
Non-Profit and Government
| Job Title | Employer | Location | Degree | Conditions | Date Posted ▾ |
|---|---|---|---|---|---|
Director, Registry OperationsDirector, Registry Operations(Click title to open job details in a new window.)Description: The Registry Operations Director will direct and manage operations for MDA’s large, multi-disease Neuromuscular Observational Research (MOVR) Data Hub, a key element of MDA’s mission to improve patient outcomes and help drive drug development. This position works across multiple departments within MDA and with external stakeholders including, but not limited to, industry, governmental agencies, academic institutions and other non-profit organizations to build and maintain the MOVR Data Hub. This position will report directly to the SVP, Scientific Program Director. Link: https://mda.jobs.net/en-US/job/registry-operations-director/J3M1LZ6QC72Q5W1D3F9 Employer: Muscular Dystrophy Association Location: Boston, MA Sector: Nonprofit Degree required: BS or BSN Conditions: NDG Job posted: May 8th, 2018 | Muscular Dystrophy Association | Boston, MA | BS or BSN | NDG | May 08, 2018 |
Senior ScientistSenior Scientist(Click title to open job details in a new window.)Description: Sage Bionetworks is recruiting a scientist with bioinformatics or computational biology experience to lead integrative genomic analysis within multiple consortia of biologists and computational biologists studying neurodegenerative and neuropsychiatric diseases. Specific Responsibilities Include: Job responsibilities include facilitating research between teams of scientists. Including implementing analyses, coordination of consortium-wide analyses, and cross-project evaluation and integration of results. These projects will advance our molecular understanding of neurodegenerative and neuropsychiatric disease biology to eventually refine disease diagnoses or targeted therapeutic intervention. Specific responsibilities will focus on leading efforts in analysis of primarily genomic data through the following activities: • Perform research through well-informed biological and methodological strategic decisions on analyses of genomic and/or imaging datasets. • Develop novel mechanisms to evaluate and combine outcomes across multiple lines of biological and statistical evidence • Develop visualizations • Create scientifically rigorous publications, communications and presentations • Lead integrated analytical efforts and interpretation of results across collaborators within consortia • Work with a high-degree of independence to complete and publish high quality research in a transparent, reproducible manner. • Coordinate data deposition and analytical outputs across multiple researchers • Utilize internally developed software tools to manage collaborations and work closely with the software team to provide feedback on the development of these tools. Basic qualifications: • Ph.D. in bioinformatics, computational biology, genomics, computer science, statistics or relevant scientific discipline with 3+ years of relevant experience or MS with 5+ years of relevant experience. • Expertise in analyzing and interpreting at-least one of the high-throughput genomics data: next generation sequencing (DNA, RNA, methylation), SNP Arrays, mass spectrometry (proteomics, metabolomics). • Proficient in at least one of following programming languages: R, Python, or Matlab Additional skills/Preferences: • Extended knowledge of statistical data analysis of genomic data • Track record of innovative publications in application of or methodological development of integrative analysis of high-dimensional data. • Expertise with integrative, mechanistic, network, and/or predictive modeling • Domain knowledge in neurobiology, neuropsychiatry or inflammatory disease. • Outstanding ability to manage a cross-disciplinary group of researchers in a collaborative project • Experience communicating advanced scientific concepts to a broad audience • Experience with high performance compute or cloud computing Link: https://sagebase.clearcompany.com/careers/jobs/567fa130-6578-58a9-f671-38e3fabbaf7b/apply?source=676017-CS-28397 Employer: Sage Bionetworks Location: Seattle, WA Sector: Nonprofit Degree required: PhD Conditions: NDG Job posted: May 7th, 2018 | Sage Bionetworks | Seattle, WA | PhD | NDG | May 07, 2018 |
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Postdoctoral Fellow, Van Damme Lab
Employer: VIBLocation: Leuven, Belgium
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: March 27, 2018
Closes: May 27, 2018
Description:
The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains.
Postdoctoral Fellow, Ferraiuolo and El-Khamisy Labs
Employer: University of SheffieldLocation: Sheffield, England
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: April 27, 2018
Closes: May 28, 2018
Description:
Applications are invited for the post of Postdoctoral Research Associate in the laboratories of Dr Ferraiuolo and Prof
Assistant or Associate Professor, Neuroscience
Employer: Case Western Reserve UniversityLocation: Cleveland, OH
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: April 20, 2018
Closes: June 20, 2018
Description:
The Department of Neurosciences, Case Western Reserve University School of Medicine invites applications for a tenure-track faculty position at the rank of Assistant or Associate Professor. We seek applicants who utilize innovative methodological approaches to investigate basic mechanisms of neural development, regeneration, or neural circuit function and how perturbation of these mechanisms contributes to neurological, neurodegenerative, and/or psychiatric diseases. The new investigator will have the opportunity to interact and collaborate with a diverse group of individuals in basic science and clinical departments within the School of Medicine, University Hospitals Cleveland Medical Center, Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, and MetroHealth Medical Center. Case Western Reserve University has an outstanding infrastructure for biomedical research including recently renovated animal facilities and core facilities supporting state-of-the-art methodologies in cellular and whole animal imaging, behavioral analyses, and proteomics and genomics. Case Western Reserve University School of Medicine has committed significant resources for major expansion of neuroscience research.
Postdoctoral Fellowship
Employer: European Molecular Biology LaboratoryLocation: Hinxton, England
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 1, 2018
Closes: July 20, 2018
Description:
The European Bioinformatics Institute (EMBL-EBI), the NIHR Cambridge Biomedical Research Centre (BRC) and the University of Cambridge School of the Biological Sciences (SBS) are now accepting applications for joint postdoctoral fellowships, supporting projects that apply computational approaches to translational clinical or biological research.
Graduate Studentship, Charlet-Berguerand Lab
Employer: Institut de Génétique et Biologie Moléculaire et CellulaireLocation: Illkirch-Graffenstaden, France
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: February 1, 2018
Closes: November 1, 2018
Description:
Recently, the most common genetic cause of ALS-FTD was identified as an expansion of CGGGGC repeats located within the first intron of the C9ORF72 gene. This mutation leads to expression of toxic dipeptide proteins translated from the GGGGCC repeats, and to decreased expression of the C9ORF72 gene. Currently, it is unclear which one of these mechanisms is the leading cause of motor neuron degeneration and death.
Assistant Professor
Employer: University of MassachusettsLocation: Amherst, MA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: October 25, 2017
Description:
The Department of Biology at the University of Massachusetts, Amherst invites applications for a tenure-track position at the rank of Assistant Professor. The successful candidate will be a part of the Institute for Applied Life Sciences (IALS), which has a primary goal of developing translational research programs and fostering interactions with industry.
Assistant Professor of Neurology
Employer: University of Southern CaliforniaLocation: Los Angeles, CA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: April 5, 2018
Description:
The Center of Image Acquisition (CIA) at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute seeks a qualified applicant for an Assistant Professor (tenure track) position in the USC Department of Neurology. The CIA serves as central resource for the development and application of advanced imaging for all neuroimaging research at the Keck School of Medicine of USC. The CIA will interact and collaborate with many departments at the Health Sciences Campus and the University Park Campus conducting research in methodology and its application in the study of normal, neurological and psychiatric cohorts. The ideal candidate should have a Ph.D. in Biophysics, Biomedical Engineering, or a related field, and have 2-3 years of postdoctoral training in the field of MRI physics and its applications in neuroscience. The candidate is expected to develop innovative MRI techniques, in particular noninvasive blood flow and perfusion imaging. The main duties of this position include the development of an independent and/or collaborative research program and participation in multidisciplinary research applying novel MRI imaging techniques for assessing and diagnosing neurovascular and neurodegenerative diseases. Experience on pulse sequence programming, particularly on Siemens platform is highly desirable.
Employer: University of Southern California
Location: Los Angeles, CA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: April 5th, 2018
Assistant Professor, Biological Chemistry and Pharmacology
Employer: Ohio State UniversityLocation: Columbus, OH
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 5, 2017
Description:
The Department of Biological Chemistry and Pharmacology, in the College of Medicine at The Ohio State University, invites applications from investigators using zebrafish as a model organism for a tenure-track faculty position at the rank of Assistant Professor. The successful candidate will join a vibrant and cohesive zebrafish community at The Ohio State University. The department has complementing strengths in motor neuron disorders, neuromuscular biology, RNA biology and epigenetics. There is also a college-wide program to enhance research in neurodegenerative diseases. Research programs that are in neurodegeneration or complement department strengths are particularly encouraged.
Assistant Professor, Biological Sciences
Employer: University of TexasLocation: Dallas, Texas
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: November 22, 2017
Description:
The Department of Biological Sciences in the School of Natural Sciences and Mathematics at the University of Texas at Dallas (http://www.utdallas.edu/biology/) invites applications for a faculty position at the rank of Assistant Professor. We seek to hire an outstanding scientist with research interests that complement and build on existing departmental strengths in biochemistry, cell and molecular biology, computational and systems biology, genomics, microbiology, and pathobiology (cancer, neurodegenerative disorders, and infectious disease). Since the department has the goal of expanding its research and teaching into new directions, we will also consider applications from excellent candidates in other areas of the biological sciences. Review of applications will begin immediately and will continue until the position is filled.
Employer: University of Texas
Location: Dallas, Texas
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: November 22nd, 2017
Assistant Professor, Cell and Molecular Biology
Employer: University of Rhode IslandLocation: Kingston, RI
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: May 16, 2018
Description:
The George and Anne Ryan Institute for Neuroscience and the Department of Cell and Molecular Biology invite applications for the position of Assistant Professor.
Assistant Professor, Developmental and Translational Neurobiology
Employer: Virginia TechLocation: Roanoke, VA
Sector: Academia
Degree Required: PhD, MD/PhD, DVM/PhD
Conditions: NDG
Posted on: November 16, 2016
Description:
The Virginia Tech Carilion Research Institute (VTCRI) has launched a new center within the institute – the Developmental and Translational Neurobiology Center (DTNC; https://wp.vtc.vt.edu/dtnc/), to expand the institute’s research programs in cellular and molecular neurobiology in healthy development, disease, and trauma. There are currently two open assistant professor faculty positions – one for a neurobiologist studying mechanisms underlying brain development or neurodevelopmental disorders and one for a neurobiologist or neuro-immunologist studying neurodegenerative disease or brain injury. Applicants should have an earned doctorate, have completed postdoctoral training and demonstrated a track record of successful research, publications and either active extramural funding (preferably from NIH) or show distinct promise to obtain such funding. The new faculty will join a collaborative and highly successful group of investigators at the VTCRI with related research interests in a variety of areas of neuroscience. Competitive salary, space and start-up packages will be provided.
Employer: Virginia Tech
Location: Roanoke, VA
Sector: Academia
Degree required: PhD, MD/PhD, DVM/PhD
Conditions: NDG
Job posted: November 16th, 2016
Assistant Professor, Developmental and Translational Neurobiology
Employer: Virginia TechLocation: Blacksburg, VA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: July 12, 2017
Description:
The Virginia Tech Carilion Research Institute (VTCRI) has launched a new center within the institute – the Developmental and Translational Neurobiology Center (DTNC; https://wp.vtc.vt.edu/dtnc/), to expand the institute’s research programs in cellular and molecular neurobiology in healthy development, disease, and trauma. There are currently two open assistant professor faculty positions – one for a neurobiologist studying mechanisms underlying brain development or neurodevelopmental disorders and one for a neurobiologist or neuro-immunologist studying neurodegenerative disease or brain injury. Applicants should have an earned doctorate, have completed postdoctoral training and demonstrated a track record of successful research, publications and either active extramural funding (preferably from NIH) or show distinct promise to obtain such funding. The new faculty will join a collaborative and highly successful group of investigators at the VTCRI with related research interests in a variety of areas of neuroscience. Competitive salary, space and start-up packages will be provided.
Employer: Virginia Tech
Location: Blacksburg, VA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: July 12th, 2017
Assistant Professor, Genetics
Employer: University of TrentoLocation: Trento, Italy
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: May 15, 2017
Description:
The Centre for Integrative Biology of the University of Trento invites candidates active in Genetics to apply for a position at the Assistant Professor level. The position is offered for a three-year period. The annual gross salary will be about 45.000 Euros. The area of research and teaching is Genetics:
Assistant Professor, Mechanisms of Neurological Disease
Employer: Emory UniversityLocation: Atlanta, Georgia
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 9, 2017
Description:
The Department of Cell Biology at Emory University School of Medicine seeks outstanding applicants to fill a tenure-path faculty position at the Assistant Professor level in the areas of Neurological Disease, including Neurodevelopmental Disorders or Neurodegeneration.
Assistant Professor, Neural Biology
Employer: Augusta UniversityLocation: Augusta, GA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: March 7, 2018
Description:
The Department of Biological Sciences at Augusta University anticipates a tenure-track position at the rank of Assistant Professor beginning in August 2018. The Department is composed of 22 full-time and 7 part-time faculty members with expertise across a broad spectrum of biological disciplines. We have a strong commitment to providing research opportunities and experience to our undergraduate students in addition to excellent classroom and laboratory instruction. As a thriving unit in this research university, faculty in the Department of Biological Sciences have both the opportunity and the expectation to help develop new undergraduate and graduate programs in the biological sciences. Within the next academic year, we expect to launch our first master’s program in Biomolecular Sciences and the faculty member hired for this position will be an integral part of this emerging program.
Assistant Professor, Neurobiology
Employer: University of CaliforniaLocation: Irvine, CA
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: September 6, 2017
Description:
Applications are invited for a position at the level of tenure-track Assistant Professor. The Department of Neurobiology and Behavior is ranked as one of the top neuroscience departments in the country and engages in interdisciplinary approaches to the study of neurobiology. The Institute for Memory Impairments and Neurological Disorders is home to one of 31 Alzheimer’s Disease Research Centers funded by the National Institutes of Health. We seek outstanding candidates whose research addresses the molecular neuropathology of Alzheimer’s disease and other neurodegenerative disorders. Preference will be given to applicants whose research integrates cutting edge neuroscientific techniques using human and animal tissue.
Assistant Professor, Neurobiology
Employer: Virginia TechPrincipal Investigator: Veterans Health Administration
Location: Blacksburg, VA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: August 30, 2017
Description:
The Virginia Tech Carilion Research Institute (VTCRI) (http://research.vtc.vt.edu) is recruiting several faculty in cellular and molecular neurobiology at the assistant professor level. The faculty will be recruited into two new centers (http://research.vtc.vt.edu/centers/) within the institute – the Developmental and Translational Neurobiology Center and the Glial Biology in Health, Disease, and Cancer Center. The faculty members will have tenure track appointments in an appropriate department and college at Virginia Tech.
Assistant Professor, Neuroinflammation Research
Employer: Barrow Neurological InstitutePrincipal Investigator: Veterans Health Administration
Location: Phoenix, AZ
Sector: Academia
Degree Required: PhD, MD, MD/PhD
Conditions: ALS, NDG
Posted on: November 17, 2016
Description:
The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to study neuroinflammation and complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/).
Assistant Professor, Neurology
Employer: University of Southern CaliforniaPrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: April 5, 2018
Description:
The USC Stevens Neuroimaging and Informatics Institute (INI) seeks highly-qualified applicants for the position of Assistant Professor (tenure-track). The successful applicant will have a minimum 5+ years experience (post doctoral degree) in imaging in aging and neurodegenerative diseases. A particular emphasis on functional and structural connectivity in Alzheimer’s disease is desired. The candidate should have specific interest in mechanistic processes of aging include neuroinflammation, and/or genetics. A strong foundation in understanding the role of imaging, genetics, and clinical phenotypes in characterizing age- and disease-related phenomena is desired. The candidate should have a PhD in Neuroscience, Psychology, or other related disciplines; a strong foundation in neuroimaging and 5+ years post-PhD research experience with a successful publication record and teaching experience is required. The applicant must demonstrate an ability to work with a highly collaborative and multidisciplinary team. Further, the applicant must have demonstrated a strong track record of obtaining independent funding to support a research program.
Assistant Professor, Neuroscience
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: Riverside, CA
Sector: Academia
Degree Required: PhD, MD, PharmD
Conditions: NDG
Posted on: January 10, 2017
Description:
In a major Neuroscience initiative, we seek to hire up to 2 tenure-track or tenured faculty members as part of a cross campus multi-disciplinary effort to study the nervous system (from development, to function, to aging, degeneration and repair). We seek researchers that collectively span multi-disciplinary levels of investigation (molecular mechanisms, circuit analysis, complex animal and human behaviors) using state of the art techniques (molecular, optogenetics, behavioral, educational, computational, imaging, EEG, genetic and research of clinical populations) applied to experimental model systems of health, injury and disease (invertebrate, vertebrate or human systems). Our goal is to recruit a team of collaborative individuals with an outstanding record, committed to excellence in research, that complement existing campus strengths. Applicants for tenured positions should also demonstrate notable scientific contributions and sustained extramural support. Successful candidates must also have clear potential or demonstrated ability to work successfully with and benefit a diverse student body.
Assistant Professor, Neuroscience and Cell Biology
Employer: University of TexasPrincipal Investigator: Veterans Health Administration
Location: Galveston, TX
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: May 16, 2017
Description:
Specific Job Related Duties
Assistant Professor, Pharmacology and Chemical Biology
Employer: Emory UniversityPrincipal Investigator: Veterans Health Administration
Location: Atlanta , GA
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: March 9, 2018
Description:
Beginning immediately, we seek investigators who will develop independent and vigorous research programs in any area of pharmacology and chemical biology. Individuals with demonstrated research interests and accomplishments in chemical biology, molecular pharmacology, systems pharmacology, as well as innovative approaches for therapeutic discovery and disease biology are encouraged to apply.
Assistant Professor, Pharmacology and Chemical Biology
Employer: Emory University School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Atlanta, GA
Sector: Academia
Degree Required: PhD and/or MD
Conditions: NDG
Posted on: December 29, 2017
Description:
The Department of Pharmacology at the Emory University School of Medicine invites applications for tenure-eligible Assistant Professor positions. Applicants for other ranks will also be considered. Beginning immediately, we seek investigators who will develop independent and vigorous research programs in any area of pharmacology and chemical biology. Individuals with demonstrated research interests and accomplishments in chemical biology, molecular pharmacology, systems pharmacology, as well as innovative approaches for therapeutic discovery and disease biology are encouraged to apply.
Assistant Project Manager – NEALS
Employer: Massachusetts General Hospital (MGH)Principal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Conditions: ALS
Posted on: August 1, 2016
Description:
The Neurological Clinical Research Institute (NCRI) develops, designs, supports and manages innovative observational and interventional trials for neurological disorders. This fast paced institute has an impressive record of efficiently organizing, overseeing, coordinating, and conducting small and large multi-center, international clinical trials. The mission of the NCRI is to accelerate translational research in neurological disorders through initiating and testing novel therapies. The NCRI also serves as a Coordinating Center for the Northeast ALS Consortium (NEALS), a non-profit, research consortium committed to the cooperative implementation, timely completion, analysis, and reporting of clinical trials and other research studies aimed at improving patient care and understanding of the disease process of Amyotrophic Lateral Sclerosis (ALS).
Assistant or Associate Clinical Professor
Employer: Stony Brook UniversityPrincipal Investigator: Veterans Health Administration
Location: Stony Brook, NY
Sector: Academia
Degree Required: MD/PhD
Conditions: NDG
Posted on: September 7, 2017
Description:
The candidate should have areas of specialty interest that would mesh well with existing priorities that include cerebrovascular diseases, neurodegenerative diseases, movement disorders, or epilepsy, but candidates with expertise in other areas will also be considered. The ideal candidate will have finished a residency plus a Neurology fellowship. The successful candidate will receive start up funding, dedicated research time to build a world-class research program and have a strong interest in an academic career. This is a tenure track position.
Employer: Stony Brook University
Location: Stony Brook, NY
Sector: Academia
Degree required: MD/PhD
Conditions: NDG
Job posted: September 7th, 2017
Assistant or Associate Professor
Employer: Medical College of GeorgiaPrincipal Investigator: Veterans Health Administration
Location: Augusta, GA
Sector: Academia
Conditions: NDG
Posted on: January 24, 2018
Description:
The Department of Cellular Biology and Anatomy, Medical College of Georgia, at Augusta University is undergoing an expansion of its research program and is seeking tenure-track faculty at the Assistant or Associate Professor levels. Academic rank will be commensurate with experience. The department is seeking candidates with an interest and expertise in diseases associated with aging. Preferential consideration will be given to investigators with research expertise related to Bone/Musculoskeletal, Renal, Visual or Neurodegenerative diseases, which will complement existing strengths within the department. Augusta University is the home of the only research-oriented, state-supported medical school in Georgia and offers an outstanding interdisciplinary environment. The research infrastructure includes state-of-the-art core facilities for confocal, multi-photon and super-resolution imaging, small animal behavior/imaging, proteomics, genomics including high throughput Illumina sequencing, flow cytometry, and electron microscopy/histology. Candidates at the Assistant Professor level must demonstrate a strong potential for research including obtaining extramural funding. Candidates at the Associate Professor level must possess external funding at the NIH R01 level and demonstrate potential for its continuation. The successful candidate will receive a nationally competitive start-up package, be expected to establish and maintain an extramurally funded research program, and participate in teaching. Applicants should submit a curriculum vitae, a statement of research objectives, a description of teaching interests/experience, and identify at least three individuals as references.
Assistant or Associate Professor
Employer: University of PIttsburghPrincipal Investigator: Veterans Health Administration
Location: Pittsburgh, PA
Sector: Academia
Degree Required: PhD, MD, or MD/PhD
Conditions: NDG
Posted on: April 13, 2018
Description:
The Department of Developmental Biology (www.devbio.pitt.edu) at the University of Pittsburgh School of Medicine is recruiting an outstanding tenure-track or tenured faculty at the Assistant to Associate Professor level. Candidates should have an innovative research program in the area of developmental neurobiology. The use of mouse, zebrafish, and/or stem cell culture or organoid models (iPSC or ES) with strong translational relevance to neurodevelopmental disorders are particularly encouraged to apply. Successful candidates must hold the PhD, MD, or MD/PhD degrees, and have a strong research program with an outstanding publication record. The successful candidate will be housed in new space at the Rangos Research Center of the Children’s Hospital of Pittsburgh with state of the art core facilities, includingFACS facility, vivarium, rodent behavioral core, small animal imaging facility, and others.
Employer: University of PIttsburgh
Location: Pittsburgh, PA
Sector: Academia
Degree required: PhD, MD, or MD/PhD
Conditions: NDG
Job posted: April 13th, 2018
Assistant or Associate Professor of Neurology
Employer: Columbia UniversityPrincipal Investigator: Veterans Health Administration
Location: New York, NY
Sector: Academia
Degree Required: MD or MD/PhD
Conditions: ALS
Posted on: May 23, 2018
Description:
The Department of Neurology of Columbia University invites applications for a tenure-track faculty position at the rank of Assistant or Associate Professor. We seek a neurologist with specialty training in neuromuscular medicine, with particular expertise in the care of patients with amyotrophic lateral sclerosis (ALS). The successful candidate will have a primary affiliation with the Eleanor and Lou Gehrig ALS Center in the Neuromuscular Medicine Division, and will focus on the care of patients with ALS and other neuromuscular disorders, including those seen in the ALS and neuromuscular clinics. In addition to supporting the clinical activities of the ALS Center, the position will expand its basic, translational and/or clinical research program. Candidates with research interests in the genetics and basic biology of motor neuron disease, the development of novel ALS therapeutics, biomarker development or brain imaging are especially encouraged to apply. As a member of the Motor Neuron Center at Columbia, the new clinician-investigator will have the opportunity to interact and collaborate with a diverse group of individuals in basic science and clinical departments within the University. The ideal candidate will have extramural funding for research.
Employer: Columbia University
Location: New York, NY
Sector: Academia
Degree required: MD or MD/PhD
Conditions: ALS
Job posted: May 23rd, 2018
Assistant or Associate Professor, Neuropathology
Employer: Brigham and Women's HospitalPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: Board-certified Neuropathologist
Conditions: NDG
Posted on: October 27, 2017
Description:
The Division of Neuropathology in Department of Pathology at Brigham and Women’s Hospital, a teaching affiliate of Harvard Medical School, is seeking an academically oriented, Board-certified Neuropathologist, at the Instructor, Assistant or Associate Professor level, with skills in surgical and autopsy neuropathology. Academic rank and salary will be commensurate with experience and accomplishments. Applicants should be committed to excellent patient care, as well as research, scholarship, and effective teaching. Experience or ability to participate in precision medicine and molecular pathology is preferred. Pathologists with academic focus in neurodegenerative, tumor, medical or any other areas of neuropathology expertise are encouraged to apply. The position will combine clinical duties and academic pursuits (research/teaching) and will be involved in the Longwood Neuropathology Training Program that includes the accredited fellowship program in adult and pediatric surgical and autopsy neuropathology at the Brigham and Women’s Hospital, Dana-Farber Cancer Institute and Children’s Hospital Boston. Candidates would be expected to take advantage of the extensive resources and collaborative interactions within the Brain Tumor Research Program, the Ann Romney Center for Neurologic Diseases, and the Neuroscience Programs of the Harvard Medical School, Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and The Children’s Hospital Boston. Applicants should also have the ability to lead or participate in research in an environment that provides substantial opportunities for clinical/ translational or basic research.
Assistant or Associate Professor, Neuroscience
Employer: Albert Einstein College of MedicinePrincipal Investigator: Veterans Health Administration
Location: New York, NY
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: October 26, 2017
Description:
The Albert Einstein College of Medicine (Einstein), together with the Montefiore Medical Center, has launched an ambitious Brain Sciences Initiative. As part of this large-scale expansion, the Dominick P. Purpura Department of Neuroscience has recruited a number of outstanding faculty, and will continue to recruit additional faculty in the coming years.
Assistant or Associate Professor, Neuroscience
Employer: University of FloridaPrincipal Investigator: Veterans Health Administration
Location: Gainesville, Florida
Sector: Academia
Degree Required: PhD
Conditions: FTD
Posted on: December 8, 2017
Description:
We are seeking individuals with research interests that complement our existing programs related to biological mechanisms and modeling of neurodegenerative diseases. Of particular interest are programs with a focus on Alzheimer’s Disease, Frontotemporal Dementia, and Parkinson’s Disease. Candidates with expertise and documented productivity in research areas that include investigation of how unfolded protein responses contribute to these diseases, with particular focus on tauopathies, are preferred. Candidates must have a desire to expand the educational landscape of the Department of Neuroscience through teaching and research training program development.
Assistant or Full Professor, Chemical Biology
Employer: Sanford Burnham Prebys Medical Discovery InstitutePrincipal Investigator: Veterans Health Administration
Location: La Jolla, CA
Sector: Academia
Degree Required: PhD or MD/PhD
Conditions: NDG
Posted on: March 17, 2017
Description:
Sanford Burnham Prebys Medical Discovery Institute (SBP) is an independent non-profit biomedical research institute that blends world-class fundamental research with drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders. The Institute invests in talent, technology, and partnerships to accelerate the translation of laboratory discoveries that will have the greatest impact on patients. Recognized for its world-class NCI-designated Cancer Center and the Conrad Prebys Center for Chemical Genomics, SBP employs more than 1,100 scientists and staff in La Jolla (San Diego), California, and Lake Nona (Orlando), Florida.
Assistant, Associate and Full Professor, Neuroscience
Employer: Scripps Research InstitutePrincipal Investigator: Veterans Health Administration
Location: Jupiter, FL
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: February 22, 2018
Description:
The Department of Neuroscience on the Jupiter, FL campus of The Scripps Research Institute (TSRI) is seeking outstanding applicants for tenure track faculty positions at all levels. We invite applications from ambitious and interactive investigators from all areas of modern neuroscience applying molecular, genetic, biochemical, biophysical, cellular anatomical, and behavioral approaches to elucidate the mechanisms underlying nervous system function and its disorders.
Assistant, Associate or Full Professor, Biomedical Sciences
Employer: University of Texas Rio Grande Valley School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Edinburg, Texas
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: December 5, 2017
Description:
The UTRGV School of Medicine is seeking Faculty members at the Assistant, Associate or Professor level experienced in research in Biomedical Sciences. The background should be in all disciplines of biomedical sciences including endocrine and metabolic diseases (such as diabetes and obesity), neuroscience and neurodegenerative diseases, cancer or oncology research and research in infectious diseases. The selected individuals will carry out high quality research projects and are expected to successfully acquire extramural research support. Laboratory space, competitive salary and start-up packages are available. Postdoctoral research experience in a top-rated research program is preferred.
Assistant, Associate or Full Professor, Chemical Neuroscience
Employer: University of MinnesotaPrincipal Investigator: Veterans Health Administration
Location: Minneapolis, MN
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: November 17, 2016
Description:
The Department of Medicinal Chemistry at the University of Minnesota invites applications for a tenure-track faculty position at the rank of Assistant, Associate, or Full Professor level. The Department is housed in the College of Pharmacy (CoP), which is ranked #2 in the Nation as a Top Pharmacy School and #3 in research funding among its peers. The position will be a twelve-month full-time appointment, with expectations in teaching (in the areas of Medicinal Chemistry & Neuroscience) and service to both the PharmD professional curriculum and also the Departmental graduate education programs. Candidates are expected to establish, maintain, and direct a major research program addressing chemical neuroscience from a medicinal chemistry/chemical biology perspective to interface with other activities within the University of Minnesota, the CoP, and the Institute for Translational Neuroscience (https://www.med.umn.edu/research/research-strengths-expertise/neuroscience/institute-translational-neuroscience ). Emphasis is placed on research in neurodegenerative disorders, epilepsy, psychiatric diseases, neuroaddiction, and neuroendocrinology, but all neuroscience sub-disciplines are encouraged to apply. Interested candidates are strongly encouraged to apply by December 15, 2016 for the first review; however, this position will remain open until filled.
Employer: University of Minnesota
Location: Minneapolis, MN
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: November 17th, 2016
Assistant, Associate or Full Professor, Environmental Health
Employer: Florida International UniversityPrincipal Investigator: Veterans Health Administration
Location: Miami, FL
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: July 13, 2017
Description:
The Department of Environmental and Occupational Health (EOH) within the Robert Stempel College of Public Health & Social Work (RSCPHSW) at Florida International University (FIU) invites applications for two tenured/tenure-track faculty member at the Assistant/Associate/Professor rank (rank and tenure commensurate with qualifications).
Assistant, Associate or Full Professor, Molecular Pharmacology & Physiology
Employer: University of South FloridaPrincipal Investigator: Veterans Health Administration
Location: Tampa, FL
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: March 22, 2018
Description:
The Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine invites applications for tenure-track faculty positions at the Assistant/Associate/Full Professor levels. A doctoral degree in medical or biomedical sciences is required. Applicants must demonstrate a strong record of academic accomplishments with NIH-supported research programs. Expertise in neuroscience, cardiovascular, splanchnic organ system, metabolism and inflammation/immunology research areas is preferred, with an emphasis on the study of molecular, cellular and systemic mechanisms. Applicants must also demonstrate a history of medical school teaching excellence and are expected to have outstanding verbal communication skills.
Assistant, Associate or Full Professor, Neurobiology
Employer: Barrow Neurological InstitutePrincipal Investigator: Veterans Health Administration
Location: Phoenix, AZ
Sector: Academia
Degree Required: PhD or MD
Conditions: ALS
Posted on: October 26, 2017
Description:
The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/). Qualified applicants holding Ph.D., M.D. or equivalent degrees will be considered for appointment at assistant, associate or full professor levels. The successful candidate will be expected to direct an extramurally-funded research program in neurodegenerative disease research using interdisciplinary approaches. Institutional strategic interests for this position are in Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and traumatic brain injury. Qualified applicants in other areas of translational neuroscience also will be considered. The successful candidate is expected to synergize/collaborate with existing research and clinical faculty, will have access to core facilities and clinical samples, and may leverage opportunities to collaborate with investigators at affiliate institutes including Phoenix Children’s Hospital, the Translational Genomics Research Institute, and the University of Arizona. The successful candidate will receive a highly competitive start-up package and salary support.
Assistant, Associate or Professor, Pharmacology
Employer: University of Southern CaliforniaPrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: July 21, 2017
Description:
The University of Southern California (USC) Titus Family Department of Clinical Pharmacy invites applications for a tenured/tenure track position at the rank of Assistant, Associate or Professor. Individuals with research interests in pharmacogenomics, pharmacometrics, bioinformatics, or medication safety are encouraged to apply.
Assistant, Associate, Full Professor, Pathology and Cell Biology
Employer: Columbia UniversityPrincipal Investigator: Veterans Health Administration
Location: New York, NY
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: October 6, 2017
Description:
The Department of Pathology and Cell Biology at the Columbia University Medical Center seeks highly qualified individuals for faculty positions in surgical pathology, clinical pathology and research. Appointments can be at the Instructor, Assistant, Associate, Professor, or Associate Research Scientist level depending on experience and qualifications. All positions require outstanding academic credentials and a record of scholarly productivity. Clinical positions require board certification and a license in NYS. Columbia University’s Department of Pathology & Cell Biology invites applications for a junior/senior level faculty position. Candidates should have a strong record of research and teaching qualifications (distinction). Candidates will be expected to sustain an active research and publication portfolio and supervise graduate students, and fellows. Candidate will play a vital role in Departmental activities.
Associate Director or Senior Manager, Business Development and Alliance Management
Employer: CytokineticsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD, MBA or JD
Conditions: ALS
Posted on: April 18, 2017
Description:
In conjunction with and reporting to the Sr. Vice President of Business Development, the Senior Manager/Associate Director, Business Development and Alliance Management will focus on building value through strategic alliances and/or licensing transactions.
Associate Professor, Cognitive Neuroscience
Employer: Northwestern UniversityPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Conditions: NDG
Posted on: July 25, 2017
Description:
The Department of Psychiatry & Behavioral Sciences and the Cognitive Neurology and Alzheimer’s Disease Center at the Northwestern University Feinberg School of Medicine are jointly searching for a cognitive neuroscientist. The successful candidate will have the credentials for a full-time tenure-track appointment (Investigator Track) at the level of Associate Professor. The candidate will have the capability to lead an independent laboratory on the experimental neuropsychology and multimodal imaging of neurodegenerative diseases and successful aging. Established track record of research achievements in these areas and expertise on the cognitive aspects of aging and dementia are desirable. The successful candidate will contribute to the academic mission of the Clinical Psychology Doctoral Program within the Department of Psychiatry and will lead his/her research program on dementia and aging within the Cognitive Neurology and Alzheimer’s Disease Center. The start date is negotiable and the position will remain open until filled.
Associate Scientist
Employer: AmgenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: January 10, 2018
Description:
Amgen is seeking an Associate Scientist to join the Neuroscience Department at our research facility in Cambridge, MA. The Associate Scientist will work independently and as part of cross-disciplinary teams. The Associate Scientist will join an energetic research team responsible for the design and execution of innovative assays and the production of high quality data with the goal of developing therapeutics for neurological disorders with an emphasis on Neurodegenerative Diseases (Parkinson’s disease, Alzheimer’s disease, and Amyotrophic Lateral Sclerosis).
Associate Scientist
Employer: ALS Therapy Development InstitutePrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Non-Profit
Degree Required: BA or BS
Conditions: ALS
Posted on: January 5, 2018
Description:
The ALS Therapy Development Institute (ALS TDI) has an opening for a full-time Associate Scientist working in the Translational Research group. The Associate Scientist will be part of the team working to develop patient-derived induced pluripotent stem cell (iPSc) collection, as well as the development and implementation of cell-based high content screens for target and drug discovery.
Associate Scientist
Employer: YumanityPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: September 8, 2017
Description:
Yumanity is seeking a talented and versatile BS/MS scientist to join our interdisciplinary team to help advance novel drug discovery programs for neurodegenerative diseases. This position will be laboratory based, and requires strong experimental skills with background in cell and molecular biology and experience in quantitative assay development. The successful candidate must be highly flexible and team-oriented. The position will report to a Principal Scientist in the Mammalian Assay Development group, and will interact across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification, stem cells and chemistry.
Employer: Yumanity
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: September 8th, 2017
Associate Scientist
Employer: Yumanity TherapeuticsPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 9, 2018
Description:
Yumanity is seeking an associate scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based and requires experimental skills in human stem cell culture, including experience differentiating patient and control-derived progenitor cells into various central nervous system cells. This position will report to a Senior Scientist in Discovery Biology and will collaborate across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry.
Employer: Yumanity Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 9th, 2018
Associate Scientist
Employer: Yumanity TherapeuticsPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: April 13, 2018
Description:
Yumanity is seeking an associate scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based and requires experimental skills in human stem cell culture, including experience differentiating patient and control-derived progenitor cells into various central nervous system cells. This position will report to a Senior Scientist in Discovery Biology and will collaborate across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry.
Associate Scientist II, ALS
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: MS
Conditions: ALS
Posted on: July 31, 2017
Description:
The Department of Neurology Research is seeking a highly talented and enthusiastic associate to join an in vitro / in vivo target discovery and validation effort in Amyotrophic Lateral Sclerosis (ALS) aimed at bringing new targets and therapeutic strategies from discovery to development. The successful candidate will be expected to support efforts to develop and validate new in vitro ALS models for candidate identification and validate findings in primary mouse tissue.
Associate Scientist II, Neuroimmunology, Research
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BSc, MSc
Conditions: NDG
Posted on: October 25, 2016
Description:
The Neuroimmunology department at Biogen is searching for a committed, enthusiastic and dependable associate scientist to assist with the design, execution and interpretation of preclinical studies for drug discovery and development. The incumbent will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative/neuroinflammatory diseases. He/she should be able to plan and execute in vivo and in vitro experiments with high level of independency, organization and scientific rigor. He/she should be able to maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members.
Associate Scientist III, ALS
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: MS
Conditions: ALS
Posted on: August 29, 2017
Description:
The Department of Neurology Research is seeking a highly talented and enthusiastic associate to join an in vitro / in vivo target discovery and validation effort in Amyotrophic Lateral Sclerosis (ALS) aimed at bringing new targets and therapeutic strategies from discovery to development. The successful candidate will be expected to support efforts to develop and validate new in vitro ALS models for candidate identification and validate findings in primary mouse tissue.
Associate Scientist III, Neuroimmunology
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: March 17, 2017
Description:
The Biogen Department of Neuro/Immunology seeks a highly motivated and keen associate scientist whose primary responsibility is to advance target validation, drug discovery and development. The individual is expected to have mastered a broad range of experimental techniques, preferably having established expertise in the field of neuroimmunology. The individual will be expected to perform with significant independence with respect to designing and executing controlled experiments, analyzing and interpreting results, establishing and executing existing or new protocols/methodologies and recommending modifications. The individual is expected to read pertinent literature and exhibit knowledge of molecular and biological processes, applying their knowledge to propose new ideas and regularly make suggestions for creative solutions to technical challenges. The individual is expected to have strong written and verbal communication skills, preparing and delivering oral presentations, posters, draft research reports and contributing to manuscripts.
Associate or Full Professor, Neuroscience
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: Riverside, CA
Sector: Academia
Degree Required: PhD, PharmD or MD
Conditions: NDG
Posted on: January 10, 2017
Description:
In a major Neuroscience initiative, we seek to hire up to 2 tenure-track or tenured faculty members as part of a cross campus multi-disciplinary effort to study the nervous system (from development, to function, to aging, degeneration and repair). We seek researchers that collectively span multi-disciplinary levels of investigation (molecular mechanisms, circuit analysis, complex animal and human behaviors) using state of the art techniques (molecular, optogenetics, behavioral, educational, computational, imaging, EEG, genetic and research of clinical populations) applied to experimental model systems of health, injury and disease (invertebrate, vertebrate or human systems). Our goal is to recruit a team of collaborative individuals with an outstanding record, committed to excellence in research, that complement existing campus strengths. Applicants for tenured positions should also demonstrate notable scientific contributions and sustained extramural support. Successful candidates must also have clear potential or demonstrated ability to work successfully with and benefit a diverse student body.
Associate or Full Professor, Neuroscience
Employer: University of VirginiaPrincipal Investigator: Veterans Health Administration
Location: Charlottesville, VA
Sector: Academia
Degree Required: PhD, MD, or MD/PhD
Conditions: NDG
Posted on: November 12, 2017
Description:
The Department of Neuroscience and Center for Brain Immunology and Glia at the University of Virginia are seeking candidates for tenure-eligible Associate and Full Professor positions.
Biocuration Scientist
Employer: AlzforumPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Non-Profit
Degree Required: PhD
Conditions: NDG
Posted on: April 12, 2017
Description:
The Biocuration Scientist is responsible for the ongoing curation of scientific databases and directories that serve the neurodegeneration research community. The databases reflect the breadth of AD research and include information on research models, mutations, biomarkers, therapeutics, and other aspects of research on AD and related disorders. The Biocuration Scientist collaborates with the scientific content manager and other Alzforum staff members to ensure that information is accurate, up to date, and consistent across the website.
Bioinformatician, Salomoni Lab
Employer: German Center for Neurodegenerative Diseases (DZNE)Principal Investigator: Veterans Health Administration
Location: Bonn, Germany
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: November 28, 2016
Description:
We are seeking an interactive and self-motivated Bioinformatician / Computational Biologist to join a team of cell and molecular biologists working on brain pathophysiology. The projects will focus on interrogating and integrating existing and new genetic and epigenetic datasets generated from genetically engineered mouse models as well as primary human samples. This programme of work is based on published/unpublished work from the team. This work will be conducted by Professor Paolo Salomoni whose research interest is nuclear function in regulation of cell fate in normal brain and CNS disease.
Employer: German Center for Neurodegenerative Diseases (DZNE)
Location: Bonn, Germany
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: November 28th, 2016
Bioinformatician, Single Cell Bioinformatics
Employer: VIBPrincipal Investigator: Veterans Health Administration
Location: Ghent, Belgium
Sector: Academia
Degree Required: MSc or PhD
Conditions: ALS
Posted on: March 6, 2018
Description:
The VIB-KU Leuven Center for Brain & Disease Research is located in Leuven, Belgium, and part of VIB and the University of Leuven (KU Leuven). With more than 300 people working in 17 labs, we study the brain in health and disease. Our research focuses on disorders such as Alzheimer’s, Parkinson’s, frontotemporal dementia and amyotrophic lateral sclerosis (ALS), but also basic research questions relating the cellular heterogeneity of the brain, brain wiring and synapse biology. These studies are integrated with immunology and studies on protein aggregation and amyloid toxicity.
Bioinformatics Specialist
Employer: German Center for Neurodegenerative Diseases (DZNE)Principal Investigator: Veterans Health Administration
Location: Tübingen, Germany
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: May 13, 2018
Description:
A Bioinformatics Staff Scientist position is available at the DZNE in Tübingen within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink. The research focus of our group is to identify genetic risk factors for neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Frontal-Temporal Dementia/Motor Neuron Disease, Progressive Supranuclear Palsy and Ataxia in close collaboration with our clinical partners. As partners in the International Parkinson’s Disease Genomics Consortium (IPDGC) (http://pdgenetics.org/), we participate in large scale genetic and genomic studies to identify new genetic risk factors and to characterize the biological consequences of these mutations and risk factors by using automated high-throughput cellular screens combined with genomic and transcriptomic approaches. For further details on the scientific program of the group, please refer to http://www.dzne.de/en/sites/tuebingen/research-groups/heutink.html.
Bioinformatics Specialist
Employer: VIBPrincipal Investigator: Veterans Health Administration
Location: Leuven, Belgium
Sector: Academia
Degree Required: MSc or PhD
Conditions: NDG
Posted on: May 16, 2018
Description:
The VIB-KU Leuven Center for Brain & Disease Research is seeking a highly motivated Single Cell Bioinformatics Specialist. You will collaborate with the 17 research groups within the Center and provide essential input on computational biology aspects of their research projects. In this job you will be confronted with exciting research questions in neurobiology and neurodegeneration; and with a broad spectrum of computational challenges and single-cell omics data sets. You will work closely with in the Laboratory of Computational Biology (Stein Aerts Lab) and with the single cell expertise unit (Suresh Poovathingal) and you will be part of an active bioinformatics community in Leuven, allowing daily interactions with colleague bioinformaticians.
Biologics Group Leader
Employer: LillyPrincipal Investigator: Veterans Health Administration
Location: Indianapolis, IN
Sector: Industry
Degree Required: PhD or MD/PhD or MD
Conditions: NDG
Posted on: March 12, 2018
Description:
The Biotechnology Discovery Research (BioTDR) Lead Generation is looking to fill a position for an experienced researcher to lead a drug discovery group passionate about discovering and enablement of large molecule drugs to combat diseases in the immunology, diabetes, oncology, neurodegenerative and pain areas. Are you a highly skilled scientist who has demonstrated ability to facilitate communication between multidisciplinary teams, coordinating complex cross-functional teams? Are you prepared to lead productive collaborations both within BioTDR, and with therapeutic area partners as well as clinical colleagues so as to identify and develop opportunities for protein therapeutics? You will participate in ongoing research projects as well as initiate new drug discovery research efforts. You should be able to work in an interdisciplinary setting, have detailed understanding of disease pathophysiology and drug hunting experience.
Employer: Lilly
Location: Indianapolis, IN
Sector: Industry
Degree required: PhD or MD/PhD or MD
Conditions: NDG
Job posted: March 12th, 2018
Biostatistician
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: MS, PhD
Conditions: ALS, NDG
Posted on: May 17, 2016
Description:
The Biostatistician is responsible for providing statistical support to nonclinical and biomarker studies or projects as assigned. He/She participates in activities in cross-functional project teams for study design and execution. He/She provides statistical consultation to teams, and ensures the incorporation of statistical input in study design and execution. He/She develops statistical analysis plans and performs statistical analyses, interprets statistical results.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: MS, PhD
Conditions: ALS, NDG
Job posted: May 17th, 2016
Biostatistician, Research Fellow
Employer: University of DublinPrincipal Investigator: Veterans Health Administration
Location: Dublin, Ireland
Sector: Academia
Conditions: ALS
Posted on: Sep 24, 2016
Description:
Applications are invited for a motivated and self-driven individual for the position of Biostatistician with the Irish ALS Research Group, hosted in the Trinity Biomedical Sciences Institute’s Academic Unit of Neurology. This project will combine high resolution structural and dynamic imaging of the brain at 3 Tesla and spectral EEG/ EMG with clinical and genomic data to identify sub-clusters of ALS patients.
CNS Pre-Clinical Research Lead
Employer: Spark TherapeuticsPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: September 15, 2017
Description:
The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for:
Chair, Department of Neuroscience
Employer: University of Connecticut School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Farmington, CT
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: January 14, 2017
Description:
The UConn School of Medicine is seeking an outstanding neuroscientist at a rank of Associate or Full Professor to become Chair of the Department of Neuroscience. Candidates with nationally recognized accomplishments in research, sustained NIH or extramural funding, and leadership experience are encouraged to apply. Desired areas of expertise include but are not limited to cellular and molecular neuroscience, chronic and neurodegenerative diseases, brain circuitry research, and neurogenesis and regeneration. This position is ideal for an energetic individual with the leadership skills and vision required to foster the health and growth of a department that values academic excellence and collaboration. The departmental faculty excel in a variety of research areas (neuroscience.uchc.edu), lead educational programs in the graduate, medical and dental schools, and provide a stimulating environment for research trainees.
Chair, Department of Neuroscience
Employer: University of Connecticut School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Farmington, CT
Sector: Academia
Degree Required: PhD or MD/PhD
Conditions: NDG
Posted on: July 28, 2017
Description:
The UConn School of Medicine is seeking an outstanding neuroscientist at a rank of Associate or Full Professor to become Chair of the Department of Neuroscience. Candidates with nationally recognized accomplishments in research, sustained NIH or extramural funding, and leadership experience are encouraged to apply. Desired areas of expertise include but are not limited to cellular and molecular neuroscience, chronic and neurodegenerative diseases, brain circuitry research, and neurogenesis and regeneration. This position is ideal for an energetic individual with the leadership skills and vision required to foster the health and growth of a department that values academic excellence and collaboration. The departmental faculty excel in a variety of research areas
Chair, Department of Translational Neurosciences
Employer: University of Arizona College of MedicinePrincipal Investigator: Veterans Health Administration
Location: Phoenix, AZ
Sector: Academia
Degree Required: PhD and/or MD
Conditions: NDG
Posted on: April 2, 2018
Description:
The University of Arizona College of Medicine – Phoenix is seeking an inaugural Chair for its new Department of Translational Neurosciences (TNS). TNS will be a novel medical school department, one that actively bridges basic science and clinical medicine through innovative collaborative research programs. The Chair will have the opportunity to create the overarching vision and, through strategic leadership, to build a center of translational neuroscience excellence. The Department Chair will have resources to recruit TNS faculty who will enhance our University of Arizona Health Sciences (UAHS) scientific community. We seek a visionary leader with expertise in molecular, cellular, or genetic approaches to neuroscience whose research is motivated by the challenges of nervous system disorders and directed toward advancing clinical care and improving human health in the foreseeable future.
Chair, Neurological Sciences
Employer: Florida State University College of MedicinePrincipal Investigator: Veterans Health Administration
Location: Tallahassee, Florida
Sector: Academia
Degree Required: PhD or MD
Conditions: NDG
Posted on: November 16, 2017
Description:
The College of Medicine at Florida State University has embarked on a strategic effort to increase basic and translational research in human neuroscience. In an effort to extend our impact in neural health, we are seeking applications for the College of Medicine’s Mina Jo Powell Chair in Neurological Sciences.
Chief of Staff, VA
Employer: University of WashingtonPrincipal Investigator: Veterans Health Administration
Location: Seattle, WA
Sector: Academia
Degree Required: MD
Conditions: NDG
Posted on: December 1, 2017
Description:
VA Puget Sound Health Care System (VAPSHCS), located in Seattle, Washington, and the University of Washington (UW) are recruiting for a Physician to serve as their Chief of Staff to provide administrative, programmatic, and clinical leadership for the medical center.
Clinical Assistant Professor, Neuropsychology
Employer: Indiana UniversityPrincipal Investigator: Veterans Health Administration
Location: Indianapolis, IN
Sector: Academia
Degree Required: Board-certified neuropsychologist preferred.
Conditions: NDG
Posted on: December 1, 2017
Description:
The Neuropsychology Section in the Department of Neurology at the Indiana University School of Medicine and Indiana University Health Physicians has an immediate opening for an Adult Neuropsychologist at the rank of Clinical Assistant Professor. The Section of Neuropsychology is situated in new space inside a unique, integrated clinical neuroscience center of excellence, comprising neurology, psychiatry, neurosurgery, and related services. Responsibilities will include coordination and provision of clinical assessment services, participation in multidisciplinary treatment teams, supervision of pre- and postdoctoral trainees and staff, and participation in the overall academic mission (including lectures to neurology residents). Major patient populations include neurodegenerative diseases, movement disorders, epilepsy, oncology, and brain injury, as well as a broad range of complex medical disorders. Although primarily a clinical position, there are significant opportunities for participation in research, including brain imaging work in alcoholism risk, Alzheimer disease, stroke, epilepsy, etc. Requirements include post-doctoral training in clinical neuropsychology and eligibility for licensure in Indiana. Preference will be given to ABPP-eligible or already board certified clinicians experienced with the above patient populations. Applications will be considered until the position is filled. Indiana University is an EEO/AA Employer, M/F/D. Qualified candidates should submit a letter of career goals and interests and a current CV to: http://indiana.peopleadmin.com/postings/5050
Employer: Indiana University
Location: Indianapolis, IN
Sector: Academia
Degree required: Board-certified neuropsychologist preferred.
Conditions: NDG
Job posted: December 1st, 2017
Clinical Cognitive Neuroscientist
Employer: University of Nebraska Medical CenterPrincipal Investigator: Veterans Health Administration
Location: Omaha, NE
Sector: Academia
Degree Required: MD, MD/PhD, or PhD
Conditions: NDG
Posted on: January 14, 2018
Description:
Cognitive Neuroscience at the University of Nebraska Medical Center. The Department of Neurological Sciences at the University of Nebraska Medical Center invites applications for a tenure leading faculty position in Clinical Cognitive Neuroscience. This position is part of a new Neuroimaging Section within the department and aims to leverage multiple hires across the School of Medicine in human neuroscience. We welcome applications from any area of cognitive neuroscience, including memory, executive function, visual attention, perception, audition, motor control, emotion, and decision-making. Methodological specialty within neuroimaging is open, but ideally the candidate would benefit from our strong existing program in MEG imaging, and develop a translational, theory-based multimodal neuroimaging program focusing on their area of interest. The successful applicant would join a growing group of cognitive neuroscientists within the department (and across campus) using MEG, fMRI, and other modalities, and hopefully help grow other programs in parallel with building their own.
Clinical Coordinator
Employer: University of MiamiPrincipal Investigator: Veterans Health Administration
Location: Miami, FL
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: October 27, 2017
Description:
The Division of Neuromuscular Disorders is seeking a Research Support Coordinator to join a very active clinical research program with multiple ongoing research studies. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). The research support coordinator will work closely with clinical research coordinators, data manager, statistician, clinical staff and the principal investigator.
Clinical Psychologist
Employer: Salford Royal NHS Foundation TrustPrincipal Investigator: Veterans Health Administration
Location: Salford, England
Sector: Academic
Conditions: FTD
Posted on: May 1, 2017
Description:
We are seeking a Clinical Psychologist with a strong interest in neuroscience and experience in neuropsychological assessment to join a well-established multidisciplinary neuroscience team specialising in early onset and/or rare dementias.
Clinical Research Coordinator
Employer: Cedars-SinaiPrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Conditions: ALS, NDG
Posted on: Oct 11, 2016
Description:
Cedars-Sinai Department of Neurology neuromuscular group is looking for an experienced Clinical Research Coordinator to join their research team. We are currently recruiting for over 10 protocols which include repositories, natural history studies, and interventional trials including pharmacological and surgical approaches.
Clinical Research Coordinator
Employer: Univ. of MiamiPrincipal Investigator: Veterans Health Administration
Location: Miami, FL
Sector: Academia
Conditions: ALS
Posted on: Sep 29, 2016
Description:
The University of Miami’s Division of Neuromuscular Disorders in the Department of Neurology is seeking a full time Clinical Research Coordinator. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). To effectively perform in this position, the Clinical Research Coordinator will ideally have experience working on investigator-initiated clinical research projects, to be able to work independently with minimal supervision and to function effectively as part of a team.
Clinical Research Fellow, Neuromuscular Diseases
Employer: CytokineticsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: MD, MD/PhD, or DO
Conditions: ALS
Posted on: April 18, 2017
Description:
We now offer a unique opportunity to an academic clinical neurologist to join our team as a Clinical Research Fellow in Neuromuscular Diseases. During a negotiable 1-2 year commitment based at Cytokinetics’ offices in South San Francisco, the Fellow will contribute invaluable expertise to our clinical development programs in neuromuscular diseases. The Fellow will benefit from an experience rarely available in a strictly academic position; i.e., the day-to-day leadership and management of a clinical trial aimed at the development of new therapeutics for patients. The Fellow may engage in this opportunity in the context of their academic fellowship as a means to satisfy a research requirement if agreeable to their institution. Continued involvement in the clinical management of patients during the period of this fellowship will be encouraged. The Fellow may return to his or her academic post at the conclusion of the term, enriched by this experience in addition to returning to the parent institution with a portfolio of valuable clinical research competencies.
Cognitive Clinical Research Nurse
Employer: University of PennsylvaniaPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: RN
Conditions: FTD
Posted on: October 6, 2017
Description:
The Cognitive Clinical Research Nurse is responsible to promote organizational values of patient and visitor satisfaction by demonstrating courtesy and respect for families, visitors and other employees. Cares for patients in all age groups from young adult through geriatrics. Demonstrates competence in the assessment, treatment and care of patients serviced. Works in collaborative practice setting with supervising/collaborating physicians to care for patients within the Penn Frontotemporal Degeneration Center.
Computational Biologist
Employer: Verge GenomicsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD, MD, MD/PhD
Conditions: ALS, NDG
Posted on: Aug 16, 2016
Description:
Verge Genomics is looking for a genomics scientist to develop algorithms, statistical methods, and software to analyze large-scale gene expression and genomic datasets. You will implement these methods to identify new disease targets and mechanisms, and drugs that target these disease gene networks. As one of the first employees at Verge, you will develop cutting-edge methods that will serve as the foundation of a revolutionary drug development model.
Data Analyst
Employer: University of Pennsylvania School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Conditions: NDG
Posted on: January 19, 2018
Description:
This analyst will work under the guidance of investigators in the Center for Biomedical Image Computing and Analytics (http://www.cbica.upenn.edu/, CBICA), Director, Christos Davatzikos, PhD.
Director of Clinical Operations
Employer: AlectorPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: MS; MBA preferred
Conditions: ALS, FTD
Posted on: July 1, 2017
Description:
At Alector, we believe that neurodegeneration and dementia, are in fact immune disorders and we made it our mission to empower the immune system to cure Alzheimer’s disease, frontotemporal dementia, ALS and other degenerative brain conditions. We are supported by leading investors in healthcare including Orbimed, Polaris, Google Ventures and count some of the most innovative pharma companies as our strategic backers.
Director of Neurodegeneration Disease Models
Employer: AlectorPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD, MD, PhD/MD
Conditions: ALS, FTD, NDG
Posted on: May 11, 2016
Description:
Alector LLC (alector.com) is a privately-funded, broad-based, neuroscience biotech startup located in the San Francisco Mission Bay. We combine state-of-the-art antibody technology with recent discoveries in human genetics to discover and clinically develop a platform of novel disease modifying therapeutics for Alzheimer’s disease, Frontotemporal dementia, Parkinson’s disease, amyotrophic lateral sclerosis, and traumatic brain injury.
Director of Neurodegeneration Disease Models
Employer: AllectorPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Conditions: ALS, FTD, NDG
Posted on: Sep 20, 2016
Description:
Alector is looking for exceptional scientists, senior scientists, and director-level investigators with a PhD and/or MD, an outstanding publication and track record, and a drive to innovate. The candidate must have extensive, hands-on expertise in conducting and managing disease model studies for neuro-degeneration and dementia, including Alzheimer’s disease, Parkinson’s disease, Frontotemporal dementia and ALS, in rodents. The successful candidates will play leading roles in the discovery and development of novel, disease-modifying drugs.
Director of Neurodegenerative Research
Employer: University of PennsylvaniaPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: July 24, 2017
Description:
We are currently on the hunt for a Director of Research– Neurodegenerative to oversee all aspects of neurodegenerative gene therapy research at the GTP at PENN. In this role, you will be responsible for build a team of Senior Research Investigators (SRI) to support GTP’s Neurodegenerative research efforts; establishing processes for mentoring and leading SRIs in research projects; directly oversee and manage a team of SRIs and technicians; In consultation with the PI of the GTP, the Research Director – Neurodegenerative will assess the rare disease programs that are brought into GTP for scientific research. The individual should have in-vivo pharmacology expertise for preclinical translational programs as well as expertise in testing the efficacy of therapeutic interventions for neurodegenerative disease indications. Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures.
Director or Senior Director, Gene Transfer Technologies
Employer: REGENXBIOPrincipal Investigator: Veterans Health Administration
Location: Rockville, MD
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: September 17, 2017
Description:
The Director/Senior Director is a recognized expert in the science and applications of gene transfer and gene therapy. The incumbent will lead the Gene Transfer Technologies research group whose mission is to:
Director, Antibody Discovery
Employer: Voyager TherapeuticsPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: May 2, 2018
Description:
Voyager is seeking a highly motivated scientist and leader with extensive experience in therapeutic antibody discovery and development to contribute to our research team and build the Antibody Platform at the company.
Director, Center for Neurodegenerative Disorders
Employer: University of MarylandPrincipal Investigator: Veterans Health Administration
Location: Baltimore, Maryland
Sector: Academia
Degree Required: MD
Conditions: NDG
Posted on: September 14, 2017
Description:
The University of Maryland Department of Neurology is seeking a senior level physician scientist with expertise in dementia and neurodegeneration to serve as the Director of the Center for Neurodegenerative Disorders. Specifically, the Department is seeking an investigator with a strong history of external funding whose work focuses on the molecular and cellular pathogenesis of neurodegenerative disorders including Alzheimer’s disease (AD), Huntington’s disease (HD), Fronto-temporal dementia (FTD), or hereditary ataxias (HA).
Director, Center for Neurodegenerative Disorders (Physician-Scientist)
Employer: University of MarylandPrincipal Investigator: Veterans Health Administration
Location: Baltimore, MD
Sector: Academia
Degree Required: MD
Conditions: FTD
Posted on: October 25, 2017
Description:
The University of Maryland Department of Neurology is seeking a senior level physician scientist with expertise in dementia and neurodegeneration to serve as the Director of the Center for Neurodegenerative Disorders. Specifically, the Department is seeking an investigator with a strong history of external funding whose work focuses on the molecular and cellular pathogenesis of neurodegenerative disorders including Alzheimer’s disease (AD), Huntington’s disease (HD), Fronto-temporal dementia (FTD), or hereditary ataxias (HA).
Director, Clinical Pharmacology
Employer: CytokineticsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: MD
Conditions: ALS
Posted on: April 18, 2017
Description:
Reporting to the EVP Research & Development, the Director, Clinical Pharmacology will be responsible principally for early clinical drug development activities with a strong focus on Phase I and Phase IIa clinical trials. He/She will work closely with the Clinical Research Group and other members of the R&D team to ensure a strategic view is taken for the pipeline progression of individual projects.
Director, Division of Neuroscience
Employer: NINDSPrincipal Investigator: Veterans Health Administration
Location: Bethesda, MD
Sector: Non-Profit
Degree Required: PhD or MD
Conditions: NDG
Posted on: October 20, 2017
Description:
The National Institute of Neurological Disorders and Stroke (NINDS) seeks a Director to lead its extramural Division of Neuroscience. The Director of the Division of Neuroscience will be responsible for planning and directing a program of extramural and collaborative research in neuroscience, guiding NINDS’s largest research portfolio and charting the future of a vibrant, growing neuroscience research community https://www.ninds.nih.gov/. The Director of the Division of Neuroscience will lead a group of approximately 60 professional staff. The research portfolio of the Division of Neuroscience includes an annual budget of over $1 billion dollars in grants and over $30 million in R&D contracts.
Director, Institute of Biotechnology
Employer: University of HelsinkiPrincipal Investigator: Veterans Health Administration
Location: Helsinki, Finland
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: June 17, 2017
Description:
Helsinki Institute of Life Science HiLIFE of the University of Helsinki is seeking a Director of the Institute of Biotechnology (bi.helsinki.fi). The Institute of Biotechnology (BI) is at the forefront of molecular biology research with eight current ERC grantees, and has a strong focus in biotechnology through developing new strategies e.g. to combat neurodegenerative and metabolic diseases. Current research programs at the BI are in Cell and Molecular Biology, Developmental Biology, Genome Biology, and Structural Biology and Biophysics. BI is an international, competitive and rewarding workplace, where the staff within the 25 research groups and 7 core facilities exceeds 250 and comes from 30 different countries. As of 2017 the Institute of Biotechnology is a unit of HiLIFE (www.helsinki.fi/hilife) and collaborates locally across life science units and organizations.
Director, Neurobiology
Employer: Verge GenomicsPrincipal Investigator: Veterans Health Administration
Location: Ann Arbor, MI
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: May 2, 2017
Description:
Verge Genomics is seeking a motivated and accomplished Director of Neurobiology with experience using in vivo pharmacology models to translate in vitro compound hits to optimized drug leads. You will lead in vivo studies to validate small molecule efficacy and minimize side effect potentials and establish proof of concept by the manipulation of gene targets to ameliorate or create disease models. The ideal candidate will apply a combination of his or her expertise in the etiology and treatment of ALS, Parkinson’s and Alzheimer’s disease, results from our cell-based screens, and animal studies you will lead to best apply gene networks to guide our drug discovery efforts. With knowledge of neuropharmacology and experience translating compound discoveries to CNS applications, this position offers the opportunity to help lead the neurobiology research program at an emerging biotech company.
Employer: Verge Genomics
Location: Ann Arbor, MI
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: May 2nd, 2017
Director, Neurodegenerative Disease Research, Cleveland Clinic
Employer: Cleveland ClinicPrincipal Investigator: Veterans Health Administration
Location: Cleveland, OH
Sector: Academia
Degree Required: PhD and/or MD
Conditions: NDG
Posted on: February 6, 2018
Description:
The Cleveland Clinic Department of Neurosciences and Neurological Institute are actively seeking a Director to head the Cleveland Clinic Neurodegenerative Disease Research Center. The Director will have the opportunity to lead, expand, and integrate basic, translational, and clinical research programs. Senior candidates with PhD and/or MD degrees and well-established, independently-funded research programs are encouraged to apply. The Department of Neurosciences, the Lerner Research Institute, and the Neurological Institute offer excellent research and core facilities, generous start-up funds, and ongoing operational support. Candidates should submit a curriculum vitae and a brief statement of research interests and vision for the Center via e-mail to nelsonc6@ccf.org.
Director, Neuropharmacology
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Conditions: NDG
Posted on: August 25, 2016
Description:
The Neuropharmacology Research group is seeking independent and motivated scientists to join a newly established research team focused on the rapid progression of novel therapeutics to humans for neurodegenerative, neurobehavioral and neuromuscular diseases. The Director, Neuropharmacology will be responsible for establishing and leading a research pharmacology group responsible for developing and leading innovative approaches to the treatment of neurodegenerative, neurobehavioral and neuromuscular disorders. The candidate will be expected to lead their own research project, as well as oversee other drug development programs with the goal of building a robust and sustainable portfolio of candidates for clinical development. The candidate will also oversee the efforts and be responsible for guiding the career development of 6-10 scientists.
Director, Neuropharmacology
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD, MD, PhD/MD
Conditions: ALS, NDG
Posted on: May 9, 2016
Description:
The Neuropharmacology Research group is seeking independent and motivated scientists to join a newly established research team focused on the rapid progression of novel therapeutics to humans for neurodegenerative, neurobehavioral and neuromuscular diseases. The Director, Neuropharmacology will be responsible for establishing and leading a research pharmacology group responsible for developing and leading innovative approaches to the treatment of neurodegenerative, neurobehavioral and neuromuscular disorders. The candidate will be expected to lead their own research project, as well as oversee other drug development programs with the goal of building a robust and sustainable portfolio of candidates for clinical development. The candidate will also oversee the efforts and be responsible for guiding the career development of 6-10 scientists.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD, MD, PhD/MD
Conditions: ALS, NDG
Job posted: May 9th, 2016
Director, Neuroscience Electrophysiology
Employer: GSKPrincipal Investigator: Veterans Health Administration
Location: Collegeville, PA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: September 18, 2017
Description:
Job Responsibilities Include:
Director, Neuroscience Research & Drug Discovery
Employer: Verge GenomicsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD, MD, MD/PhD
Conditions: ALS, NDG
Posted on: Aug 16, 2016
Description:
Verge Genomics is seeking a motivated and highly accomplished “drug hunter,” responsible for directing, managing, and leading basic research and drug discovery efforts for neurodegenerative diseases and leading multidisciplinary project teams. This position offers the opportunity to grow and lead a drug discovery program at an emerging biotech from the ground up, while establishing important external partnerships. As a member of the early team at Verge, you will be deeply involved in key strategic decisions and in organization of the research & discovery team, and help build the foundation of a revolutionary drug development model.
Director, Registry Operations
Employer: Muscular Dystrophy AssociationPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Nonprofit
Degree Required: BS or BSN
Conditions: NDG
Posted on: May 8, 2018
Description:
The Registry Operations Director will direct and manage operations for MDA’s large, multi-disease Neuromuscular Observational Research (MOVR) Data Hub, a key element of MDA’s mission to improve patient outcomes and help drive drug development. This position works across multiple departments within MDA and with external stakeholders including, but not limited to, industry, governmental agencies, academic institutions and other non-profit organizations to build and maintain the MOVR Data Hub. This position will report directly to the SVP, Scientific Program Director.
Employer: Muscular Dystrophy Association
Location: Boston, MA
Sector: Nonprofit
Degree required: BS or BSN
Conditions: NDG
Job posted: May 8th, 2018
Director, Therapeutic Development
Employer: University of Pennsylvania School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Conditions: NDG
Posted on: April 18, 2018
Description:
We are currently seeking a new Director of Therapeutic Development to over see the Program of Excellence focused on Neurodegenerative Diseases.
Director/Senior Director of Neurodegeneration and Repair Research
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD or PhD/MD
Conditions: FTD
Posted on: March 5, 2017
Description:
We are looking for a talented leader to direct preclinical research in Dementia and Memory Disorders within the new Neurodegeneration and Repair Research Unit. In close partnership with the early clinical lead for within the same unit, the successful candidate will be responsible for delivering innovative drug candidates for proof-of-concept trials in AD, FTD and other memory disorders. He/she will lead the efforts of multiple research teams from early target discovery to late preclinical development and support the clinical trial strategy. We seek a candidate with knowledge of the biology of neurodegeneration and an outstanding track record in the field of drug development. He/she will succeed by collaborating closely with other Biogen scientists and clinicians in the areas of neurodegeneration, neuroimmunology and repair, as well as experts in the multiple therapeutic modalities – small molecules, antibodies, biologics, antisense oligonucleotides and gene therapy – in the Biogen portfolio. An innovative approach to biomarker and drug delivery strategies will also be required. We particularly seek candidates who have demonstrated strong scientific rigor while exploring novel pathways and mechanisms in humans and model systems and in leading multidisciplinary research teams. Demonstrated expertise in Alzheimer’s research and experimental models would be an advantage but is not required.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD or PhD/MD
Conditions: FTD
Job posted: March 5th, 2017
Director/Sr. Director, Neurodegeneration and Repair Research
Employer: BiogenPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD or PhD/MD
Conditions: FTD
Posted on: October 23, 2017
Description:
We are looking for a talented leader to direct preclinical research in Dementia and Memory Disorders within the new Neurodegeneration and Repair Research Unit. In close partnership with the early clinical lead for within the same unit, the successful candidate will be responsible for delivering innovative drug candidates for proof-of-concept trials in AD, FTD and other memory disorders. He/she will lead the efforts of multiple research teams from early target discovery to late preclinical development and support the clinical trial strategy. We seek a candidate with knowledge of the biology of neurodegeneration and an outstanding track record in the field of drug development. He/she will succeed by collaborating closely with other Biogen scientists and clinicians in the areas of neurodegeneration, neuroimmunology and repair, as well as experts in the multiple therapeutic modalities – small molecules, antibodies, biologics, antisense oligonucleotides and gene therapy – in the Biogen portfolio. An innovative approach to biomarker and drug delivery strategies will also be required. We particularly seek candidates who have demonstrated strong scientific rigor while exploring novel pathways and mechanisms in humans and model systems and in leading multidisciplinary research teams. Demonstrated expertise in Alzheimer’s research and experimental models would be an advantage but is not required.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD or PhD/MD
Conditions: FTD
Job posted: October 23rd, 2017
Electrophysiologist
Employer: Novartis Pharma AGPrincipal Investigator: Veterans Health Administration
Location: Basel, Switzerland
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: May 24, 2017
Description:
The Musculoskeletal disease area research department at the Novartis Institutes for BioMedical Research (NIBR) in Basel, Switzerland, is looking for a Scientific Associate with excellent electrophysiology skills to join a highly motivated research team that aims to identify and develop therapies for neuromuscular diseases and peripheral neuropathies like amyotrophic lateral sclerosis and sarcopenia.
Epidemiologist I
Employer: MA Department of Public HealthPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Non-Profit and Government
Degree Required: BS, MS, PhD
Conditions: ALS
Posted on: May 4, 2016
Description:
Serves as Registry Coordinator for the Massachusetts statewide registry of amyotrophic lateral sclerosis (ALS). Responsibilities include those related to the day-to-day operation of the Registry, including contact with all patient reporting sources to ensure complete case ascertainment, oversight of data abstraction and data verification activities, data entry of all clinical files received, and the management of all electronic and paper Registry files. This position is also responsible for maintaining a clean and accurate Registry database, conducting statistical analyses on program evaluation and ALS epidemiology in Massachusetts, assisting in the preparation of statistical reports, attending public meetings, and working with other technical staff on special studies. Other duties will include organizing annual advisory committee meetings and collaborating with other Bureau of Environmental Health (BEH) staff in the design and implementation of other environmentally-related chronic disease surveillance systems.
Employer: MA Department of Public Health
Location: Boston, MA
Sector: Other
Degree required: BS, MS, PhD
Conditions: ALS
Job posted: May 4th, 2016
Executive Director, Clinical Research, Rare and Neurological Diseases
Employer: PfizerPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: MD or MD/PhD
Conditions: NDG
Posted on: November 29, 2017
Description:
The Rare Disease Research Unit is looking for a talented senior physician scientist to join our team developing transformational new treatments in rare Neuromuscular, Neurodevelopmental and Neurodegenerative diseases using AAV gene therapy. This individual will focus on the challenging translational, clinical and regulatory problems presented by gene therapy in rare (often) pediatric indications, including natural history studies, novel endpoint development and clinical trial design. The candidate will be accountable for the delivery of translational and clinical development plans for AAV gene therapy programs in multiple rare neurological indications, and will be skilled in early clinical program design and conduct from pre-clinical stages to POC. Similar activities will be required for programs exploiting other treatment modalities. Experience and proven collaborative skills with basic and clinical scientists, investigators, regulators and safety functions are essential.
Faculty Position – Assistant Professor, Neuroinflammation Research
Employer: St. Joseph's Hospital and Med Ctr / Barrow Neurological InstitutePrincipal Investigator: Veterans Health Administration
Location: Phoenix, Arizona
Sector: Academia
Conditions: ALS, NDG
Posted on: Aug 1, 2016
Description:
Faculty Position – Dept. of Neuroscience
Employer: Mayo ClinicPrincipal Investigator: Veterans Health Administration
Location: Jacksonville, FL
Sector: Academia
Conditions: ALS, FTD, NDG
Posted on: August 16, 2016
Description:
The Department of Neuroscience at Mayo Clinic in Jacksonville, FL, is seeking outstanding candidates with dynamic research programs in neurobiology of disease and aging. The ideal candidate for this position will be an investigator with an innovative and dynamic research program that is directed at understanding the fundamental role of disease biology in neurodegenerative disease including Alzheimer’s disease, Parkinson’s disease, Frontotemporal dementia, and Amyotrophic Lateral Sclerosis. Specific areas of interest include cerebrovascular disease, CNS immunity, neurobiology of aging, stem cell biology, neurodegeneration and neuroregeneration across a range of neurological disorders. We are seeking a world-class researcher to participate in departmental and institutional initiatives emphasizing collaboration and team science.
Faculty Position – Neuroinflammation Research
Employer: St. Joseph's Hospital and Medical CenterPrincipal Investigator: Veterans Health Administration
Location: Phoenix, AZ
Sector: Academia
Conditions: ALS, NDG
Posted on: Jul 5, 2016
Description:
The BARROW NEUROLOGICAL INSTITUTE seeks an exceptionally promising or accomplished investigator to study neuroinflammation and complement other translational neuroscience research in a unique and dynamic environment within the Division of Neurobiology at the Barrow Neurological Institute (https://www.barrowneuro.org/).
Faculty Position in Academic Faculty of Health Sciences
Employer: Curtin UniversityPrincipal Investigator: Veterans Health Administration
Location: Perth, Western Australia
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: April 27, 2016
Description:
Curtin University is seeking to appoint an Associate Professor/Professor, to further strengthen Western Australia’s research on neurological disorders and neuroscience, at the soon to be completed Sarich Neuroscience Research Institute building. You will take a leadership role in fostering translational research and links with industry and community groups.
Employer: Curtin University
Location: Perth, Western Australia
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: April 27th, 2016
Faculty Position in Computational & Systems Biology
Employer: University of PennsylvaniaPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: PhD, MD
Conditions: NDG
Posted on: April 8, 2016
Description:
The Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Assistant or Associate Professor position in the tenure track. The successful applicant will have experience in the field of Computational & Systems Biology with a focus on neurodegenerative diseases, including modeling cellular and molecular interactions and pathways, use of model organisms for generating human disease oriented leads, analysis of large genomic and phenotype data sets, and personalized medicine for central nervous system disorders.
Employer: University of Pennsylvania
Location: Philadelphia, PA
Sector: Academia
Degree required: PhD, MD
Conditions: NDG
Job posted: April 8th, 2016
Faculty Position in Neuroinflammation and Neurodegeneration
Employer: University of Tennessee Health Science CenterPrincipal Investigator: Veterans Health Administration
Location: Memphis, TN
Sector: Academia
Degree Required: PhD, MD
Conditions: ALS, NDG
Posted on: May 3, 2016
Description:
The Department of Anatomy and Neurobiology at the University of Tennessee Health Science Center seeks an outstanding researcher in the area of neuroinflammation and neurodegeneration to fill an open rank tenure-track position. We seek candidates to complement and extend departmental and campus-wide research on the role of microglia/neuroinflammation in neurodegenerative diseases, especially, but not limited to, traumatic brain injury, chronic traumatic encephalopathy, stroke, Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis.
Employer: University of Tennessee Health Science Center
Location: Memphis, TN
Sector: Academia
Degree required: PhD, MD
Conditions: ALS, NDG
Job posted: May 3rd, 2016
Faculty Positions in Aging & Metabolism Research Program
Employer: Oklahoma Medical Research FoundationPrincipal Investigator: Veterans Health Administration
Location: Oklahoma City, OK
Sector: Academia
Degree Required: PhD
Conditions: ALS, NDG
Posted on: April 26, 2016
Description:
The Oklahoma Medical Research Foundation (OMRF) is seeking established investigators to maintain a research program that addresses issues relevant to mechanisms of sarcopenia and frailty, neuromuscular junction maintenance, aspects of age-related changes in muscle physiology, or mechanisms of age-related neurodegeneration. Candidates with significant knowledge of diseases of neuromuscular degeneration, such as ALS, are of special interest.
Faculty, Department of Biopharmaceutical Sciences
Employer: University of IllinoisPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: March 8, 2018
Description:
The University of Illinois at Chicago, College of Pharmacy, Department of Biopharmaceutical Sciences (http://go.uic.edu/BPS) invites applications for an open rank tenure-track faculty position in the field of pharmaceutics, drug delivery, or therapeutic bioengineering. Of particular interest are candidates with training and research interests in the areas of biologics, biopharmaceutical processing, formulation, and delivery. Special attention will be given to candidates whose research complements and expands our research in the areas of cancer, neurodegenerative diseases and/or the human microbiome.
Genetic Counselor
Employer: Massachusetts General HospitalPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: MS
Conditions: ALS
Posted on: January 05, 2017
Description:
Working in the Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital (MGH) the genetic counselor will collaborate with and support the Amyotrophic Lateral Sclerosis (ALS) multidisciplinary clinical research team. The incumbent must have prior genetic counseling experience and a desire to be a key component of a team working to define the field of ALS genetics research. The majority of work will remain in the research realm; however, there will be opportunity to assist with complex ALS cases within the MGH ALS Multidisciplinary clinic or MGH Brain Health Clinic.
Employer: Massachusetts General Hospital
Location: Boston, MA
Sector: Academia
Degree required: MS
Conditions: ALS
Job posted: January 5th, 2017
Graduate Research Assistant
Employer: Massachusetts General HospitalPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS, FTD
Posted on: April 27, 2017
Description:
The laboratory is seeking a motivated Graduate Research Assistant to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis (ALS) and dementia. There is an increased focus on altered RNA processing as a central component of neurodegeneration in ALS and frontotemporal dementia. Our group explores the role of RNA alterations in neuronal death and uses splicing and expression profiles to identify therapeutic strategies that correct disease-linked gene expression events. The successful candidate will lead a research project using various cellular and animal models of ALS to explore disease mechanisms. Under the supervision of the Principal Investigator, the candidate will design and perform experiments, will participate to the scientific lab meetings and is expected to fully participate in the organization and joint upkeep of the laboratory. He/She will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, preparation of libraries for high throughput sequencing, and mammalian cell cultures. Experience in mouse handling and mouse histology is preferred. The individual must pay attention to details, be capable of working independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team.
Graduate Studentship
Employer: KU LeuvenPrincipal Investigator: Veterans Health Administration
Location: Leuven, Belgium
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: August 22, 2017
Description:
The project will focus on the composition and biological impact of protein aggregates in ALS throughout the evolution of the disease and among the different types of the disease (e.g. C9ORF72-related ALS). To identify steps of different types of protein aggregate maturation human brain samples will be analyzed biochemically and neuropathologically. The biological effects (e.g. on nucleocytoplasmic transport) and toxicity of the aggregates will be tested in cell culture systems of human-derived induced pluripotent stem cells (iPSCS).
Graduate Studentship
Employer: University of SheffieldPrincipal Investigator: Veterans Health Administration
Location: Sheffield, England
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: January 8, 2018
Description:
We are looking for highly motivated candidates to explore the role of C9ORF72 in neurodegeneration associated with amyotrophic lateral sclerosis (ALS). ALS is a motor neuron disease characterised by progressive injury and death motor neurons in the brain and spinal cord. Recent reports suggest that C9ORF72 hexanucleotide intronic repeat expansion cause ALS with high prevalence in both familial and sporadic cases. The C9ORF72 gene is located on chromosome 9p (9p21) and encodes twelve exons, with three transcription variants, and two possible protein isoforms, termed a and b. The normal expansion typically comprises a fewer than 30 of GGGGCC repeats. Pathogenic expansions consists of hundreds to thousands repeats. RNA foci are observed in fibroblasts and CNS of patients with C9ORF72 expansion, suggesting defects of RNA metabolism. Despite the significant progress in C9orf72 research, the exact function of the C9orf72 protein remains unclear. Thus, further research efforts aimed at better understanding the role of C9ORF72 protein are of the utmost importance to enable therapeutic development for ALS.
Graduate Studentship, Basso Lab
Employer: University of TrentoPrincipal Investigator: Veterans Health Administration
Location: Trento, Italy
Sector: Academia
Degree Required: MS
Conditions: ALS
Posted on: July 24, 2017
Description:
The major focus of the project is on extracellular vesicles and motor neuron degeneration with a particular interest on the role of RNA in the glia-motoneuronal intercellular communication. The PhD student will acquire expertise on extracellular vesicles analysis, RNA profiling in the field of neurodegeneration.
Employer: University of Trento
Location: Trento, Italy
Sector: Academia
Degree required: MS
Conditions: ALS
Job posted: July 24th, 2017
Graduate Studentship, De Vos Lab
Employer: University of SheffieldPrincipal Investigator: Veterans Health Administration
Location: Sheffield, England
Sector: Academia
Degree Required: BS
Conditions: ALS, FTD
Posted on: April 14, 2017
Description:
Applications are now being invited for a three-year Basic Science PhD Studentship funded by Alzheimer’s Society, starting in October 2017. The successful candidate will join an established training programme at the Sheffield Institute for Translational neuroscience (SITraN) in the group of Dr Kurt De Vos. Expansions of a noncoding GGGGCC hexanucleotide repeat in the C9ORF72 gene are the most common genetic defect found to date in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). How the repeat expansion causes disease is not known, but appears to involve both loss-of-function (C9ORF72 haploinsufficiency), and gain-of-function (repeat-associated non-ATG (RAN) translation, RNA toxicity) mechanisms. To unravel the ways in which C9orf72 expansions cause disease it is crucial to understand the normal functions of the C9orf72 protein. In this project we will investigate how the cellular levels of C9orf72 are regulated and leverage this knowledge to devise novel therapeutic strategies. Candidates must have a first or upper second class honors degree or significant research experience.
Graduate Studentship, Kadener Lab
Employer: Hebrew UniversityPrincipal Investigator: Veterans Health Administration
Location: Jerusalem, IL
Sector: Academia
Degree Required: BS
Conditions: NDG
Posted on: September 7, 2017
Description:
We are looking for a highly motivated student to investigate the contribution and role of circular RNAs (circRNAs) in the development of neurodegenerative diseases. The student will join the Kadener lab in Jerusalem, a multidisciplinary team studying the role of circRNAs in physiology and disease in Drosophila. The position is part of circTrain (https://circtrain.eu/) an EU-funded International Training Network (ITN) that focuses on different aspects of circRNA biology.
Graduate Studentship, Locker Lab
Employer: University of SurreyPrincipal Investigator: Veterans Health Administration
Location: Guildford, England
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: May 11, 2018
Description:
Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS) areneurodegenerative disorders (NDs) with proteostasis defects. They represent an ideal set of diseases covering >70% of patients to increase our understanding of the molecular basis of NDs. The associated pathologies are difficult to truly model and compare using animals because (i) they are mainly caused by sporadic forms of the diseases, and (ii) models do not recapitulate the basic cellular changes observed in patients. Our aim is to achieve a global understanding of RNA translation and stress granules regulation across these neurodegenerative diseases using novel genetically engineered isogenic human stem cell lines. This will identify key regulatory nodes, across diseases, revealing new points for therapeutic interventions.The PhD candidate will work as part of an EU/MRC-funded trans-national consortium that has developed control fibroblasts genetically engineered into disease cell lines (project grant MR/R02426X/1), allowing studies within identical genetic backgrounds. Following training with our project partners at McGill (Canada) and QMUL (UK), the control and disease-model iPSCs will be used to differentiate neuronal cell populations including forebrain cortical-like neurons, midbrain dopamine-like and glial astrocyte-like cells. Subsequently, the candidate will be trained in confocal microscopy techniques to detect and quantity stress granules in cells, measure translational activity globally and specifically at the mRNA level using ribosomes profiling.
Graduate Studentship, Maudsley Lab
Employer: VIBPrincipal Investigator: Veterans Health Administration
Location: Antwerp, Belgium
Sector: Academia
Degree Required: MS
Conditions: FTD
Posted on: July 24, 2017
Description:
The aim of this project is to disentangle the converging molecular pathomechanisms in the frontotemporal dementia – amyotrophic lateral sclerosis spectrum. We will pursue this goal by investigating different mouse models using state-of-the-art proteomic and transcriptomic technologies. Using this approach, we intend to unravel the disease mechanisms already at presymptomatic stages.
Employer: VIB
Location: Antwerp, Belgium
Sector: Academia
Degree required: MS
Conditions: FTD
Job posted: July 24th, 2017
Graduate Studentship, Vande Velde Lab
Employer: CRCHUMPrincipal Investigator: Veterans Health Administration
Location: Montréal, Canada
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: June 20, 2017
Description:
Dr. Christine Vande Velde is looking to recruit a graduate student to her laboratory located at the CRCHUM facility, a research center affiliated with the Université de Montréal and located in Downtown Montreal.
Group Leader, Neurobiology
Employer: UKRI MRC Laboratory of Molecular BiologyPrincipal Investigator: Veterans Health Administration
Location: Cambridge, England
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: May 10, 2018
Description:
The Neurobiology Division of the Medical Research Councils Laboratory of Molecular Biology (MRC LMB) invites applications for a Programme Leader-Track position. We seek a scientist with a focus on the elucidation of fundamental molecular mechanisms that determine the structure and function of the neuronal synapse, in health and disease. An emphasis on the development and application of molecular neurobiological approaches is essential, and the application of cutting-edge light and/or electron microscopic imaging is encouraged. The primary selection criteria are scientific excellence and potential for synergy with our existing research programmes, both within the Division (encompassing neuronal molecular cell biology, neural circuits and simple behaviours, and the molecular/ cell biological basis of neurodegeneration) and across the wider LMB. You should hold a PhD and have an excellent publication record, be internationally recognised for your work and have outstanding potential for independent research.
Group Leader, Translational Biomarkers
Employer: DenaliPrincipal Investigator: Veterans Health Administration
Location: South San Francisco, CA
Sector: Industry
Conditions: NDG
Posted on: Sep 03, 2016
Description:
Denali Therapeutics is seeking to recruit a Group Leader to lead the company’s translational biomarker efforts. S/he will be responsible for leading translational biomarker strategies and developing and implementing biomarker assays to assess the target engagement and PK/PD/response relationships of drug candidates in both preclinical models and clinical trials.
Head of Translational Science
Employer: University of Texas Southwestern Medical SchoolPrincipal Investigator: Veterans Health Administration
Location: Dallas, TX
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: January 18, 2018
Description:
The University of Texas Southwestern Medical Center, Center for Alzheimer’s and Neurodegenerative Diseases (CAND), is seeking applications for a faculty position as Head of Translational Science. Responsibilities include supporting the translation of novel targets and inventions into viable drug development and/or patient care solutions, engaging with Principal Investigators (PI’s), postdocs, and students to advance inventions from CAND laboratories, advancing high-throughput screening (HTS) hits into lead series, optimizing lead series to IND-ready clinical candidates, connecting entrepreneurs, bankers, and venture funds with CAND science, and utilizing Contract Research Organization (CRO) network to rapidly and cost-effectively advance CAND programs. Appointment rank will be commensurate with academic accomplishments and experience.Candidates must have a Ph.D. in chemistry, life sciences or a related discipline, practical experience in advancing drug programs into the clinic and validation of novel targets with in vivo proof of concept experiments.Desired skills include medicinal chemistry and DMPK expertise, hit and lead series evaluation, competitive analysis of programs, intellectual property path advisement, ability to connect CAND PI’s with resources such as CRO’s for chemistry and pharmacology, on-campus capabilities and UT System resources, grant writing, and design and interpretation of clinically relevant PI/PD experiments.
Employer: University of Texas Southwestern Medical School
Location: Dallas, TX
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: January 18th, 2018
Junior or Senior Group Leader
Employer: Grenoble Institute of NeurosciencesPrincipal Investigator: Veterans Health Administration
Location: Grenoble, France
Sector: Academia
Degree Required: PhD and/or MD
Conditions: NDG
Posted on: September 15, 2017
Description:
The Grenoble Institute of Neurosciences (GIN), an outstanding research center devoted to understanding brain functions and the development of innovative clinical therapies for neurological, neuromuscular and psychiatric disorders, is welcoming applications for positions as junior and senior group leaders in basic and/or clinical research.
Lab Manager
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Academia
Degree Required: BS
Conditions: FTD
Posted on: April 30, 2017
Description:
The position is for a Lab Manager to help facilitate all daily lab operations. The individual will report to a Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders. A successful candidate will have excellent communication skills, highly confident decision making ability, experience managing multiple projects and life sciences lab management, and embrace the highly dynamic environment.
Lab Manager, Neurosciences Clinical Research Unit
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Academia
Degree Required: BA or BS
Conditions: FTD
Posted on: June 9, 2017
Description:
The position is responsible for, and critically important to Neurosciences Clinical Research Unit (NCRU), and Memory and Aging Center (MAC) investigators for the overall operational management of clinical research activities for the biospecimens processing lab. The Lab Manager has direct responsibility for implementing a diverse portfolio of processing protocols which include multicenter clinical trials (both NIH and industry-sponsored), local investigator-initiated clinical trials, and clinical research activities, including a clinical database and biorepository LIMS system.
Lab Technician, Grinberg Lab
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Academia
Degree Required: BA/BS
Conditions: FTD
Posted on: May 26, 2017
Description:
The position is for a part time Lab Technician / Staff Research Associate I (SRA I) to assist the Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus ( see http://grinberglab.ucsf.edu). The candidate is expected to be open to learning new methods.
Medical Director
Employer: Denali TherapeuticsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: MD or MD/PhD, Neurology
Conditions: NDG
Posted on: February 15, 2018
Description:
Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to the genetics and biology of neurodegeneration and the principles of translational medicine. In anticipation of the Company’s growth plans, Denali Therapeutics is seeking to recruit a Medical Director. The Medical Director will be responsible for design, implementation, monitoring, analysis, and reporting of clinical trials and will provide strategic leadership for development programs.
Employer: Denali Therapeutics
Location: San Francisco, CA
Sector: Industry
Degree required: MD or MD/PhD, Neurology
Conditions: NDG
Job posted: February 15th, 2018
Neurobiology Research Associate II
Employer: Verge GenomicsPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: May 24, 2017
Description:
Verge Genomics is seeking a Neurobiology Research Associate II to join the Drug Discovery team. This candidate will gain pharmaceutical industry experience in a cutting-edge academic lab in the SF Bay Area and at Verge Genomics headquarters in SF. The candidate will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative diseases. The candidate will conduct in vivo studies in mice, including neonatal intracerebroventricular injections, and drug administration by oral routes. Experience with stereotaxic surgery, gene therapy (AAV9 or ASO), behavioral observations, gait analysis, rotarod and grip strength, and genotyping are a plus. The ideal candidate will have excellent problem-solving skills and familiarity with statistical analysis. This position reports to a PhD Scientist. The candidate will also culture motor neurons differentiated from induced pluripotent human stem cells and aid in the design and development of cellular assays to identify genes and compounds for treating neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). The candidate will have extensive experience with sterile in vitro laboratory tasks, including harvesting, storing, growing, and expanding neuronal cultures, formulating and adding compounds and molecular probes, measuring cell numbers with light microscopy and properties based on immunohistochemical markers, and writing SOPs and detailed records of all work.
Employer: Verge Genomics
Location: San Francisco, CA
Sector: Industry
Degree required: BS or MS
Conditions: ALS
Job posted: May 24th, 2017
Neurologist
Employer: UT Southwestern Medical CenterPrincipal Investigator: Veterans Health Administration
Location: Dallas, TX
Sector: Academia
Degree Required: MD
Conditions: FTD
Posted on: February 3, 2018
Description:
The Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern Medical Center is accepting applications for a Board eligible/certified neurologist with an interest in cognitive and memory disorders. Research areas could include: 1) Running clinical trials; and 2) Studying clinical/pathological correlations of imaging and blood/CSF biomarkers. This faculty position will have a joint appointment in the Department of Neurology and Neurotherapeutics and the work will involve the interface of clinical and basic research.
Neurologist
Employer: Centre Hospitalier Universitaire de NicePrincipal Investigator: Veterans Health Administration
Location: Nice, France
Sector: Academia
Degree Required: MD
Conditions: ALS
Posted on: May 5, 2018
Description:
The Peripheral Nervous System, Muscle and ALS Department, Pasteur 2 new Hospital, CHU de Nice (France) is actually seeking a Neurologist with immediate availability for a Clinical and Research position. This department is certified as Neuromuscular Diseases Reference Center and ALS Reference Center. These Centers are affiliated to French rare diseases Healthcare Network (FILNEMUS) and French rare diseases Healthcare Network: Amyotrophic lateral sclerosis and rare motor neuron diseases (FILSLAN). The Department has also been labeled as being part of the European Reference Networks-NeuroMuscular Diseases (ERN-NMD) as Center of Excellence.
Neurologist, Rehabilitation Service
Employer: University of OklahomaPrincipal Investigator: Veterans Health Administration
Location: Oklahoma City, OK
Sector: Academia
Degree Required: MD
Conditions: ALS
Posted on: July 7, 2017
Description:
As a neurologist on the Neurology and Rehabilitation Service at the Oklahoma City Veterans Affairs Health Care System,who subspecializes in rehabilitation. The duties of this position include: supervise residents and students and attend on the neurology inpatient service 2-3 months annually; attend on the rehabilitation inpatient service2-3 months annually; direct the power-mobility clinic; direct the spinal cord injury, spinal cord diseases, multiple sclerosis, and amyotrophic lateral sclerosis clinic; direct the stroke-care program. The applicant must be able toprovidecare and rehabilitation tothe following populations ofveterans: acute neurology patients in all outpatient and outpatient settings including intensive care units and emergency room; spinal cord injury, spinal cord disease, ALS and MS in the Hub and Spoke system of care; disabled patients due to neurological or orthopedic impairments for rehabilitation care on outpatient and inpatient settings. The applicant must be able to provide acute stroke and post-stroke care and supervise neurology stroke fellows who rotate at the VA. The applicant must participate in ongoing CARF accreditations activities for a Comprehensive Integrated Inpatient Rehabilitation Program, and assist in meeting standards forspecial accreditation in Stroke Rehabilitation. The applicant must be able to supervise neurology stroke fellows, neurology residents, other trainees and students who rotate on the Neurology Inpatient and Outpatient Service, and therefore must meet criteria for faculty appointment in Neurology at the University of Oklahoma Health Science Center.
Employer: University of Oklahoma
Location: Oklahoma City, OK
Sector: Academia
Degree required: MD
Conditions: ALS
Job posted: July 7th, 2017
Neuropathologist, Physician Scientist, Neurodegenerative Disease
Employer: Northwestern UniversityPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Degree Required: MD or MD/PhD, and Board-certified in Neuropathology
Conditions: NDG
Posted on: March 26, 2018
Description:
The Department of Pathology at Northwestern University Feinberg School of Medicine seeks a full-time Assistant Professor, Associate Professor or Professor on the tenure track. Qualified candidates will be physician-scientists MD or MD, PhD, and be Board-certified in Neuropathology. They are expected to develop a federally funded, independent research program in the area of neurodegeneration and engage in collaborations with other researchers who study neurodegenerative diseases throughout Northwestern University.
PI, Medicinal Chemistry and Drug Discovery
Employer: Southern ResearchPrincipal Investigator: Veterans Health Administration
Location: Birmingham, AL
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: August 22, 2017
Description:
SOUTHERN RESEARCH is seeking an outstanding scientist to join the faculty of the Chemistry Department in the Drug Discovery Division. We are particularly interested in attracting a scientist with an established research program with excellent translational potential toward the identification of novel therapeutic agents. Chemists with a strong desire to collaborate with biochemists, microbiologists, and our high-throughput screening center, especially in the areas of oncology, anti-infectives, or CNS and neurodegenerative diseases, are particularly encouraged to apply.
PhD Position – Motor Neuron Disease
Employer: University of SheffieldPrincipal Investigator: Veterans Health Administration
Location: Sheffield, UK
Sector: Academia
Conditions: ALS
Posted on: August 16, 2016
Description:
An exciting opportunity has arisen for a PhD project in the field of neuroimaging in motor neuron disease (MND). MND is a devastating, fatal, incurable neurodegenerative condition that typically results in death within 2-3 years. Therapeutic efforts have been limited by an incomplete understanding of disease pathophysiology, and because an available biomarker is lacking with which to track therapeutic effects over short timescales; for this reason, many potential agents never make it to clinical trial. There is increasing evidence for abnormal energy metabolism in MND, both a hypermetabolic early phase characterised clinically by weight loss and, later, mitochondrial failure, which may contribute to motor neuronal cell death.
Physician Scientist, Tenure-Track
Employer: Temple UniversityPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: MD or MD/PhD
Conditions: ALS
Posted on: March 31, 2017
Description:
The Center for Translational Medicine (CTM) at the Lewis Katz School of Medicine at Temple University is seeking qualified candidates and candidate nominations for a Tenure Track Faculty Physician-Scientist dedicated to neurodegeneration research. This position will also have clinical responsibilities and a joint appointment in the Department of Neurology.
Physician, Neuropathologist
Employer: West Virginia University School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Morgantown, WV
Sector: Academia
Degree Required: MD, MD/PhD or DO
Conditions: NDG
Posted on: January 22, 2018
Description:
West Virginia University School of Medicine, Department of Pathology, Anatomy and Laboratory Medicine seeks an academically oriented, Board Certified/eligible Neuropathologist qualified for appointment at either the Assistant Professor, Associate Professor, or Professor rank with skills in surgical and autopsy neuropathology. Experience and ability to participate in other pathology specialty functions is desirable but not required. Pathologists with an academic focus in the neurosciences (eg, neurodegenerative disorders, tumor, stroke, etc) are encouraged to apply. Other service responsibilities and the effort levels designated in support of our academic and clinical service missions will be based on a candidate s training, skills and passions, as well as departmental and institutional needs. In addition to providing patient care, the successful candidate will be involved in the teaching of medical students and residents. For appointment at the Associate Professor or Professor rank, it is expected that candidates sustain an outstanding, extramurally supported research program.
Physician, Physical Medicine & Rehabilitation
Employer: Veterans AffairsPrincipal Investigator: Veterans Health Administration
Location: St. Louis, MO
Sector: Academia
Degree Required: MD
Conditions: ALS, SCI
Posted on: April 29, 2018
Description:
The ideal candidate would be preferably Physical Medicine & Rehabilitation (PM&R), Spinal Cord Injury/Dysfunction fellowship-trained. Experience in Spinal Cord Injury-Disability (SCI-D), Spinal Cord Injury (SCI), Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), PM&R. Board Certified/Board Eligible in SCI is preferred. Candidates with board certification or board eligibility in SCI are eligible to apply regardless of residency specialization, and will be given preference in the application, but fellowship is not exclusively required if residency training is in PM&R.
Employer: Veterans Affairs
Principal investigator: Veterans Health Administration
Location: St. Louis, MO
Sector: Academia
Degree required: MD
Conditions: ALS, SCI
Job posted: April 29th, 2018
Physician-Scientist (Faculty)
Employer: Temple UniversityPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: MD or MD/PhD
Conditions: ALS
Posted on: August 28, 2017
Description:
Lewis Katz School of Medicine at Temple University
Physician-Scientist, Tenure-Track
Employer: Temple UniversityPrincipal Investigator: Veterans Health Administration
Location: Philadelphia, PA
Sector: Academia
Degree Required: MD or MD/PhD
Conditions: ALS
Posted on: December 15, 2016
Description:
The Center for Translational Medicine (CTM) at the Lewis Katz School of Medicine at Temple University is seeking qualified candidates and candidate nominations for a Tenure Track Faculty Physician-Scientist dedicated to neurodegeneration research. This position will also have clinical responsibilities and a joint appointment in the Department of Neurology.
Post-Doctoral Fellow Research, RIC Sensory Motor Performance Program
Employer: Rehabilitation Institute of ChicagoPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Degree Required: PhD, MD, PhD/MD
Conditions: ALS, stroke, SCI
Posted on: October 25, 2016
Description:
General Summary: The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).
Postdoctoral Fellow
Employer: SanofiPrincipal Investigator: Veterans Health Administration
Location: Framingham, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: June 21, 2017
Description:
Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly qualified and motivated Postdoctoral Scientist to investigate the underlying disease biology of amyotrophic lateral sclerosis (ALS). The successful candidate will implement manifold in vitro and in vivo experimental approaches to help identify and validate innovative therapeutic targets for the treatment of ALS. These techniques include molecular biology, biochemistry, cell culture, immunoblotting, immunohistochemistry, microscopy, laser capture microdissection and the use of transgenic mouse models.
Postdoctoral Fellow
Employer: Shirley Ryan Ability LabPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: April 15, 2018
Description:
The PostDoc Fellow will participate in the discovery and evaluation of candidate targets affecting motor unit function and subsequent sensory motor performance following stroke, SCI, and/or ALS. The PostDoc Fellow may also be expected to study the effects of various clinical interventions in order to aid the design of rehabilitation strategies targeting specific motor unit properties.
Postdoctoral Fellow
Employer: University of LuxembourgPrincipal Investigator: Veterans Health Administration
Location: Esch-sur-Alzette, Luxembourg
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 29, 2017
Description:
The international “Regulatory T cell responses at the crossroads of immune homeostasis and inflammation in the context of barrier diseases” (TregBar) project is an international research project funded by the Luxembourg National Research Fund`s (FNR) bilateral AFR funding instrument. The program will initiate long-term collaborations between the biomedical initiatives of the Luxembourg Institute of Health (Esch-sur-Alzette, Luxembourg) and the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg with the RIKEN Center for Integrative Medical Sciences (IMS) in Yokohama, Japan.
Postdoctoral Fellow
Employer: A*StarPrincipal Investigator: Veterans Health Administration
Location: Singapore
Sector: Non-profit
Degree Required: PhD
Conditions: NDG
Posted on: February 7, 2017
Description:
The lab for microRNA Models of Neurodegenerative Disease at the Institute of Molecular and Cell Biology is seeking to recruit a highly motivated Research Fellow to investigate pathogenic pathways underlying neurodegeneration linked to loss of microRNA function.
Postdoctoral Fellow
Employer: Northwestern UniversityPrincipal Investigator: Veterans Health Administration
Location: Evanston, IL
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: December 22, 2017
Description:
The successful candidate will participate in federal and private-funded projects aiming to understand the role and molecular mechanism of autophagy (an essential lysosomal degradation pathway) in the regulation of metabolism and animal behavior, using knockout, knockin and transgenic mice, cell biology, biochemistry, imaging and state-of-the-art behavioral techniques.
Employer: Northwestern University
Location: Evanston, IL
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: December 22nd, 2017
Postdoctoral Fellow
Employer: NovartisPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: May 2, 2018
Description:
We are seeking a highly motivated postdoctoral associate interested in proteinopathy research in the context of neurodegenerative diseases. The successful candidate will be responsible for developing in vitro models to understand underlying mechanisms of pathogenic protein inclusion formation in the brain. The ideal candidate should have excellent communication and writing skills and the ability to work well in a multidisciplinary team. The candidate will periodically present his/her results and will prepare manuscripts for publication of findings in a peer-reviewed journal.
Employer: Novartis
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: May 2nd, 2018
Postdoctoral Fellow, Boulis Lab
Employer: Emory UniversityPrincipal Investigator: Veterans Health Administration
Location: Atlanta, GA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: October 4, 2017
Description:
The Boulis laboratory in the department of Neurosurgery at Emory University in Atlanta, GA, is seeking a capable and self-motivated individual to oversee projects involving the transplantation of iPS cells for the treatment of motor neuron diseases and nerve damage.
Postdoctoral Fellow, Buchan Lab
Employer: University of ArizonaPrincipal Investigator: Veterans Health Administration
Location: Tucson, AZ
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: September 5, 2017
Description:
A position is available in the Buchan lab to study cytoplasmic mRNA biology. We are particularly interested in the assembly, disassembly and function of stress granules and P-bodies, which are cytoplasmic mRNA-protein (mRNP) assemblies that are implicated in regulation of mRNA translation, storage and decay. Recent evidence also suggests important roles for these mRNP bodies in viral defense, cancer and neurodegenerative diseases. A related focus is on the role of vesicular trafficking pathways in mediating clearance of P-bodies, stress granules and aggregates of proteins implicated in neurodegenerative disease such as Amyotrophic Lateral Sclerosis (ALS).
Postdoctoral Fellow, Cai Lab
Employer: Rutgers UniversityPrincipal Investigator: Veterans Health Administration
Location: Piscataway, NJ
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: March 31, 2017
Description:
The Department of Cell Biology and Neuroscience at Rutgers University is currently accepting applications for a postdoctoral position to study (1) the cellular mechanisms regulating autophagy-lysosomal function; (2) how altered axonal transport impacts the autophagy-lysosomal system, leading to axonal degeneration; (3) how deficits in the endolysosomal pathway contribute to the dysregulation of neuronal signaling. Given that defective axonal transport has been implicated in the pathogenesis of major neurodegenerative diseases, our studies will yield fundamental information to advance our understanding of human neurodegenerative diseases. Candidates for this position should hold a PhD with a strong research background in neurobiology or cell biology, at least in one of these areas: membrane trafficking, organelle transport, mitochondrial quality control, neuronal signaling, and neurodegenerative mouse models. Interested individuals should send CV, a personal statement describing research interests, and names and details of 3 references to cai@biology.rutgers.edu. Att: Qian Cai, M.D., Ph.D. Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Nelson Biological Laboratories, Busch Campus, 604 Allison Road, Piscataway, NJ 08854. Lab Webpage: https://cbn.rutgers.edu/cb-profile/userprofile/qc29 Application review will begin immediately and will continue until a suitable candidate is selected.
Employer: Rutgers University
Location: Piscataway, NJ
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 31st, 2017
Postdoctoral Fellow, Da Cruz Lab
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: San Diego, CA
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: March 10, 2018
Description:
The Da Cruz laboratory focuses on disease mechanisms and therapy development for human neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), the second most common dementia. The laboratory combines sophisticated mouse genetics, cutting-edge stem cell and genome editing approaches to model human neurological disorders in vitro.
Postdoctoral Fellow, De Paola Lab
Employer: Imperial College LondonPrincipal Investigator: Veterans Health Administration
Location: London, England
Sector: Academia
Degree Required: PhD or MD/PhD
Conditions: NDG
Posted on: February 22, 2017
Description:
A Postdoctoral Research Fellowship is available in the Laboratory of Synaptic plasticity and Repair of Imperial College London, starting immediately. The aim of this project is to gain new and fundamental insights into the cellular and molecular mechanisms that regulate the regeneration of adult neocortical circuits. We have previously demonstrated that certain populations of cortical neurons exhibit enhanced spontaneous regenerative capacity compared to others, and we are now interested in understanding the mechanisms responsible for this differential response to injury. Our goal is to develop effective strategies to enhance functional axon and synaptic regeneration (Holtmaat et al Nature protocols 2009; Canty et al Nature Communications 2013; Grillo et al Nature Neuroscience 2015).
Postdoctoral Fellow, Deleidi Lab
Employer: German Center for Neurodegenerative DiseasesPrincipal Investigator: Veterans Health Administration
Location: Tübingen, Germany
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: April 5, 2018
Description:
A position for a talented and highly motivated Postdoctoral Researcher is available within the scientific team “Mitochondria and Inflammation in Neurodegeneration” led by Michela Deleidi in Tübingen. The research focus of our group is on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in neurodegenerative diseases. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson’s disease. Our aim is to understand, at the molecular level, how immune responses within or outside the brain contribute to neurodegeneration. Our final goal is to translate fundamental discoveries to better preventive and therapeutic approaches for neurodegenerative diseases. Please see our website for more information about our research: https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/deleidi/research-areasfocus/.
Postdoctoral Fellow, Dupuis Lab
Employer: Inserm U1118Principal Investigator: Veterans Health Administration
Location: Strasbourg, France
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: April 4, 2018
Description:
A 3-year post-doctoral position is available in Inserm U1118, Strasbourg, France under the supervision of Dr Luc DUPUIS.
Postdoctoral Fellow, Durham Lab
Employer: McGill UniversityPrincipal Investigator: Veterans Health Administration
Location: Montreal, Canada
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: March 30, 2018
Description:
A postdoctoral position in ALS research is available in the laboratory of Dr. Heather Durham in the Rare Neurological Diseases Group at the Montreal Neurological Institute, McGill University, Montreal QC Canada. The project involves investigating the role of chromatin remodeling as a convergent mechanism in ALS and in neuronal stress responses (see https://www.ncbi.nlm.nih.gov/pubmed/28973294). The work would include investigation of epigenetic mechanisms in primary culture models, mouse models and post-mortem tissue as well as participation in a drug study in mouse and tissue culture models of ALS. This multidisciplinary project is funded by MDA and by an ALS Canada-Brain Canada Hudson Translational Team Grant involving collaborators with complementary expertise at other Canadian universities.
Postdoctoral Fellow, Farese-Walther Lab
Employer: Harvard School of Public HealthPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: PhD or MD/PhD
Conditions: NDG
Posted on: March 16, 2017
Description:
We have a postdoctoral position available in the laboratory of HHMI Investigator, Tobias Walther, Ph.D., and Robert V. Farese, Jr, M.D., who jointly run a highly collaborative group at the Harvard School of Public Health. The lab is located in the Boston Longwood medical campus and is affiliated with the Department of Genetics and Complex Disease (HSPH), the Department of Cell Biology (Harvard Medical School), the Broad Institute of MIT and Harvard, and the Howard Hughes Medical Institute.
Postdoctoral Fellow, Fitzpatrick Lab
Employer: Columbia UniversityPrincipal Investigator: Veterans Health Administration
Location: New York, NY
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 13, 2017
Description:
The Fitzpatrick lab, a member of the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University in the City of New York (https://zuckermaninstitute.columbia.edu/), has openings for four postdoctoral scientists opportunities.
Postdoctoral Fellow, Fraenkel Lab
Employer: MITPrincipal Investigator: Veterans Health Administration
Location: Cambridge, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: September 1, 2017
Description:
Are you an expert in neurodegeneration, with a passion for research that will have an impact on curing disease? We seek a talented post-doc to participate in an unprecedented study of the neurodegenerative disease ALS. Working with researchers at clinical and academic institutions across the United States, we are gathering data on approximately 1,000 ALS patients and controls. Induced pluripotent stem cell (iPSC) lines are being derived from each individual and these are being used to generate motor neurons for a wide range of omic studies. Our collaboration seeks to identify different subtypes of the disease, identify correlations between molecular pathways and clinical symptoms and propose therapeutic strategies.
Postdoctoral Fellow, Gopal Lab
Employer: Yale University School of MedicinePrincipal Investigator: Veterans Health Administration
Location: New Haven, CT
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: April 17, 2018
Description:
Motivated PhD graduates seeking research training in the cell biology of neurodegenerative disease are invited to apply to postdoctoral research position(s) in the Department of Pathology at Yale University. Successful candidates will utilize live cell and super-resolution imaging techniques, mass spectroscopy/CyTOF and biochemistry in primary neurons and mouse models, iPSC-derived neurons, and/or patient tissue samples to define the molecular mechanisms driving assembly, transport, and cellular functions of neuronal ribonucleoprotein (RNP) complexes under physiologic conditions and in neurodegenerative disease.
Postdoctoral Fellow, Guo Lab
Employer: Yale UniversityPrincipal Investigator: Veterans Health Administration
Location: New Haven, CT
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 8, 2017
Description:
Postdoctoral positions are available in Dr. Junjie Guo’s lab in the Department of Neuroscience at Yale School of Medicine. The Guo lab studies questions at the intersection between RNA biology and neuroscience. Currently, we are interested in the roles of mRNA and noncoding RNA structures in neurodevelopment and neurodegenerative diseases, taking a combination of computational, biochemical, genetic, and genomic approaches. Our lab is situated within the dynamic and collaborative RNA biology and neuroscience communities at Yale that includes the Yale Center for RNA Science and Medicine, the Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR), and the Kavli Institute for Neuroscience at Yale.
Postdoctoral Fellow, Heutink Lab
Employer: German Center for Neurodegenerative Diseases (DZNE)Principal Investigator: Veterans Health Administration
Location: Tübingen, Germany
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: February 16, 2018
Description:
A position for a post-doctoral researcher is available from 01.03.2018 within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink in Tübingen.
Postdoctoral Fellow, Hickman and Shuler Labs
Employer: University of Central FloridaPrincipal Investigator: Veterans Health Administration
Location: Orlando, FL
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: February 16, 2018
Description:
This post doctoral research opportunity focuses combining microfabrication and cell culture to construct in vitro models of the human body or “Body-on-a-Chip” for use in drug development. Multiple organs and their physiological interactions are represented on a single device; these interactions are based on physiologically based pharmacokinetic models. Of particular interest will be to combine metabolically active tissue, such as from the liver, with electrically active tissues such as cardiac myocytes or neuronal cells and then conduct pharmacological studies in this system.
Postdoctoral Fellow, Hu Lab
Employer: Cornell UniversityPrincipal Investigator: Veterans Health Administration
Location: Ithaca, NY
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: September 12, 2017
Description:
A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply. Please visit http://hu.wicmb.cornell.edu/ for more details and send your CV and 3 letters of references.
Employer: Cornell University
Location: Ithaca, NY
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: September 12th, 2017
Postdoctoral Fellow, Kalra Lab
Employer: University of AlbertaPrincipal Investigator: Veterans Health Administration
Location: Alberta, Canada
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: March 19, 2018
Description:
Postdoctoral positions are available in the ALS Neuroimaging Research Unit at the University of Alberta. The mission of the lab is to further our understanding of the biology of amyotrophic lateral sclerosis (ALS) using advanced MRI methods. The lab is directed by Dr. Sanjay Kalra, a neurologist and researcher, and the director of the Canadian ALS Neuroimaging Consortium (CALSNIC).
Postdoctoral Fellow, Khurana Lab
Employer: Brigham and Women's HospitalPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: February 20, 2018
Description:
One postdoctoral position is available in the Khurana laboratory (khuranalab.bwh.harvard.edu) at Harvard Medical School and Brigham and Women’s Hospital.
Postdoctoral Fellow, Knowles Lab
Employer: University of CambridgePrincipal Investigator: Veterans Health Administration
Location: Cambridge, England
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: November 24, 2017
Description:
Applications are invited for a Postdoctoral Research Associate (PDRA) to work on the development and applications of a microfluidic platform for analysing of Fused in Sarcoma (FUS) protein assembly, with a focus on liquid-liquid phase transitions using recombinant protein, cellular and cultured neuron systems, a project funded by the Wellcome Trust. The PDRA will work in the group of Professor Knowles in the Department of Chemistry.
Postdoctoral Fellow, Liachko lab
Employer: VA HospitalPrincipal Investigator: Veterans Health Administration
Location: Seattle, WA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 3, 2018
Description:
A postdoctoral research position is available in the Liachko lab located at the Veterans Affairs hospital in Seattle, and affiliated with the University of Washington (http://depts.washington.edu/geront/directory/bios/liachko.html). We use model systems including mouse primary neurons, cultured human cells and C. elegans, to study the neurodegeneration seen in amyotrophic lateral sclerosis, Alzheimer’s disease, and other aging related disorders.
Postdoctoral Fellow, Meyer Lab
Employer: Nationwide Children's HospitalPrincipal Investigator: Veterans Health Administration
Location: Columbus, OH
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: February 21, 2018
Description:
The Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital to move additional programs forward.
Postdoctoral Fellow, Mueller Lab
Employer: University of Massachusetts Medical CenterPrincipal Investigator: Veterans Health Administration
Location: Worcester, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: March 21, 2018
Description:
We seek a talented and motivated postdoc to join the laboratory of Dr Christian Mueller in the Horae Gene Therapy Center at the University of Massachusetts Medical School. Our dynamic and collaborative research environment at UMMS includes world renowned clinicians and scientists. Additionally, our location close to Boston supports many collaborations with academic and industrial research groups.
Postdoctoral Fellow, Neurobiology of Aging and Neurodegenerative Disease
Employer: University of ArizonaPrincipal Investigator: Veterans Health Administration
Location: Phoenix, AZ
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: January 19, 2017
Description:
The collaborative and interactive Arizona postdoctoral fellowship program in Neurobiology of Aging and Neurodegenerative Disease is seeking highly qualified applicants for positions supported by a National Institutes of Health training grant. Institutions included in the research consortium include the University of Arizona, Arizona State University, Barrow Neurological Institute, The Translational Genomics Research Institute, Banner Alzheimer’s Institute, Banner Sun Health Research Institute, and Mayo Clinic. All institutions are participants in the state wide Arizona Alzheimer’s Consortium. Training programs afford the opportunity to study neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Amyotrophic Lateral Sclerosis, Traumatic Brain Injury, other related disorders, as well as non-pathological brain aging. Areas of interest include behavioral, systems and clinical neurosciences, molecular neurobiology and epigenetics, brain imaging, genomics, computational and statistical analysis of complex data sets, experimental therapeutics, and clinical neuropathological research. Research resources include human longitudinal cohorts and data sets, a brain and body research donation program, PET and MRI research programs, wild type and transgenic rodent, non-human primate and human behavioral testing facilities, and cutting-edge cellular and molecular biological research methods with emphasis within each of the noted disciplines. Trainees will benefit from a Professional Development Committee to foster career development from an omnibus perspective, and the training experience will be enriched via opportunities to work, learn, and produce across institutions, driven by a collaborative experimental training plan. This is a U.S. Government funded training grant and is only available to U.S. citizens or Permanent Residents. All institutions involved in this training program value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. Because, we seek a workforce with a wide range of perspectives and experiences, we encourage diverse candidates to apply, including people of color, women, veterans, and individuals with disabilities.
Postdoctoral Fellow, Neurogenetics
Employer: UMC UtrechtPrincipal Investigator: Veterans Health Administration
Location: Utrecht, The Netherlands
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 16, 2017
Description:
As postdoc you will be working on data from Project MinE (www.projectmine.com). This is unique genomic dataset in the field of Amyotrophic Lateral Sclerosis (ALS), a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles, which include epigenetic, whole genome sequencing and clinical data of several thousand of ALS patients and matched controls. We have recently published the first results of this dataset (Van Rheenen et al. Nat Genet. 2016 (PMID: 27455348), and Kenna et al. Nat. Genet. 2016 (PMID: 27455347)). Your focus will be on exploring adding external controls and cases to this dataset while preserving type I error in case-control comparisons, annotating the non-coding genome by integrating our data with other publicly available omics datalayers, including RNAseq, Hi-C and Chip-seq and relating this to case-control status. Another type of genomic variation potentially related to ALS we are interested in, is structural variation. This means you need to have experience in working with raw sequencing data on a large number of samples and be able to apply complex genetic statistics in this context. There is a suitable ICT setup available for you to achieve this. We expect you to be able to use various bioinformatic tools on next-generation sequencing data and combine these to identify possible novel ALS risk genes, and pathological pathways. Also, we would like you to integrate these genetic data with drug databases in order to prioritize potential new drug targets for ALS and repurposing of existing drugs for ALS. This part of the work will be done in collaboration with a biotech company. You will also be expected to participate in writing scientific papers and grant applications, provide methodological advice to other members of the team (bioinformaticians, PhD students, postdocs, technicians), and participate in educating bachelor and master students.
Employer: UMC Utrecht
Location: Utrecht, The Netherlands
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: May 16th, 2017
Postdoctoral Fellow, Pathology
Employer: University of SydneyPrincipal Investigator: Veterans Health Administration
Location: Sydney, Australia
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: October 10, 2017
Description:
This position is funded by ForeFront, an NHMRC Program grant, that brings together a multidisciplinary research team to address the diagnosis, management and treatment of frontotemporal dementia and related disorders. A junior postdoctoral researcher is required to contribute to projects exploring the pathogenesis of neurodegeneration with a particular focus on immune-mediated mechanisms. This is a valuable opportunity to expand your research skills.
Postdoctoral Fellow, Plowman Lab
Employer: University of FloridaPrincipal Investigator: Veterans Health Administration
Location: Gainesville, FL
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: January 5, 2018
Description:
The Department of Speech, Language, and Hearing Sciences at the University of Florida has a funded post-doctoral associate position available to work in the Swallowing Systems Core under the direct mentorship of Dr. Emily Plowman. This line is funded by an R01 grant from the National Institute of Neurological Disorders and Stroke (N.I.N.D.S) in the area of bulbar dysfunction in individuals with Amyotrophic Lateral Sclerosis. The successful post-doctoral associate would have the opportunity to work in the Swallowing Systems Core (SSC) that combines the expertise of both Dr. Plowman and Dr. Ianessa Humbert. The Swallowing Systems Core (SSC) is housed within the Dental Tower of Shands Hospital in the University of Florida Health Science Center and is equipped with its own research dedicated C-arm to perform high-resolution videofluoroscopy, fiberoptic endoscopic evaluation of swallowing workstation and high resolution manometry set up. The SSC currently comprises two Co-directors (Plowman and Humbert), two full time clinical coordinators, a biomedical engineer, four doctoral students, seven masters’ thesis students and five undergraduate honors students. The successful applicant would be expected to work cohesively with the entire SSC team.
Postdoctoral Fellow, Respiratory Physiology
Employer: University of WisconsinPrincipal Investigator: Veterans Health Administration
Location: Madison, WI
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 11, 2017
Description:
Applications are being solicited for two NIH post-doctoral fellowships in respiratory neurobiology at the University of Wisconsin-Madison. The first position will investigate cellular mechanisms and physiological significance of neuroplasticity in the control of breathing, with an emphasis on sleep apnea. The second position will investigate functional outcomes of ex vivocell therapy (stem cell-based trophic factor delivery) to preserve respiratory motor neuron and diaphragm function in rodent models of Amyotrophic Lateral Sclerosis (ALS).
Postdoctoral Fellow, Sajjadi Lab
Employer: University of CaliforniaPrincipal Investigator: Veterans Health Administration
Location: Irvine, CA
Sector: Academia
Degree Required: MD or PhD
Conditions: FTD
Posted on: March 14, 2017
Description:
The Department of Neurology at the University of California, Irvine, invites applications for a post-doctoral fellow position in the laboratory of Dr. S. Ahmad Sajjadi MD, PhD beginning early 2017. The appointment is for 1 year with the possibility of extension upon satisfactory performance. We are seeking a highly motivated investigator with previous experience in neuropsychological assessments. Priority will be given to candidates with a recent PhD in neuroscience, psychology, or related fields and strong organizational and communication skills. The main purpose of this appointment is to establish a cohort of atypical dementia syndromes (mainly frontotemporal dementia) at the University of California, Irvine who will undergo regular clinical and neuropsychological assessments. Assessment of language and spontaneous speech will be a focus of the research and therefore, background in disorder of language will be desirable as is previous experience in neuro-imaging acquisition/analysis since the project will include structural MRI and PET scans. The position requires an individual who is an effective team player, highly organized, and innovative.
Postdoctoral Fellow, Sareen Lab
Employer: Cedar Sinai Medical CenterPrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Degree Required: MD, PhD, VMD, or DDS
Conditions: ALS
Posted on: June 22, 2017
Description:
Dr, Dhruv Sareen’s independent research laboratory at the Cedars-Sinai Medical Center, Regenerative Medicine Institute focuses on using human iPSC technology to understand the molecular mechanisms underlying neurodevelopmental/degenerative diseases and how obesity is linked to the brain. His laboratory is particularly interested ‘disease-in-a-dish’ modeling for neuromuscular, neurodegenrative and motor neuron diseases including, amyotrophic lateral sclerosis (ALS). They are particularly interested in C9orF72 and other genetic forms of ALS and what are the common elements with sporadic forms of ALS. Using the iPSC platform his lab has developed novel methods for drug screening on patient motoneurons and dissecting mechanisms for motoneuron degeneration. In the context of stem cell modeling of neurodevelopmental (SMA) and neurodegenerative diseases (ALS) Dr. Sareen’s group is particularly interested in the mechanistic insights how specific neural cell types degenerate during the disease processes. They are using OMICS (proteome, transciptome, metabolome) and imaging methodologies to gain mechanistic insights into the mitochondrial and endorplasmic reticulum stress involvement. In addition, by understanding how the cells of the nervous system develop and differentiate we will be able to develop better and safer cells for transplantation and regenerative therapies. Dr. Sareen’s group has extensive experience in pluripotent and neural stem cell research. He has developed and directed a well-renowned human iPS cell core. He has published high-profile manuscripts on human iPSC-based disease modeling in SMA and ALS.
Postdoctoral Fellow, Sareen Lab
Employer: Cedars SinaiPrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: April 17, 2018
Description:
Dr. Dhruv Sareen’s independent research laboratory at the Cedars-Sinai Medical Center, Regenerative Medicine Institute focuses on using human iPSC technology to understand the molecular mechanisms underlying neurodevelopmental/degenerative diseases and how obesity is linked to the brain. His laboratory is particularly interested ‘disease-in-a-dish’ modeling for neuromuscular, neurodegenrative and motor neuron diseases including, amyotrophic lateral sclerosis (ALS). They are particularly interested in C9orF72 and other genetic forms of ALS and what are the common elements with sporadic forms of ALS. Using the iPSC platform his lab has developed novel methods for drug screening on patient motoneurons and dissecting mechanisms for motoneuron degeneration. In the context of stem cell modeling of neurodevelopmental (SMA) and neurodegenerative diseases (ALS) Dr. Sareen’s group is particularly interested in the mechanistic insights how specific neural cell types degenerate during the disease processes. They are using OMICS (proteome, transciptome, metabolome) and imaging methodologies to gain mechanistic insights into the mitochondrial and endorplasmic reticulum stress involvement. In addition, by understanding how the cells of the nervous system develop and differentiate we will be able to develop better and safer cells for transplantation and regenerative therapies. Dr. Sareen’s group has extensive experience in pluripotent and neural stem cell research. He has developed and directed a well-renowned human iPS cell core. He has published high-profile manuscripts on human iPSC-based disease modeling in SMA and ALS.
Postdoctoral Fellow, Shirley Ryan AbilityLab
Employer: Shirley Ryan AbilityLabPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: December 1, 2017
Description:
The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).
Postdoctoral Fellow, Strittmatter Lab
Employer: Yale School of MedicinePrincipal Investigator: Veterans Health Administration
Location: New Haven, CT
Sector: Academia
Degree Required: PhD
Conditions: FTD
Posted on: October 12, 2017
Description:
Postdoctoral positions are available to study neural repair and/or neurodegeneration in Stephen Strittmatter’s laboratory.
Postdoctoral Fellow, Sun Lab
Employer: Johns Hopkins University School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Baltimore, MD
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: April 10, 2018
Description:
Postdoctoral opportunities are available in Dr. Shuying Sun’s laboratory at Johns Hopkins University School of Medicine. The lab will explore the fascinating frontiers of RNA metabolism dysfunction and RNA-targeting therapy in neurodegenerative diseases by combining molecular and cellular approaches, genome editing, proteomic, genomic and screening platforms.
Postdoctoral Fellow, Taylor Lab
Employer: St Jude Children's Research HospitalPrincipal Investigator: Veterans Health Administration
Location: Memphis, TN
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: November 10, 2017
Description:
A postdoctoral position to study the molecular and cellular mechanisms of neurodegenerative disease, including amyotrophic lateral sclerosis and frontotemporal dementia, is available at the St. Jude Children’s Research Hospital in Memphis, TN, USA. We identified that many of neurodegenerative diseases are caused by defects in the assembly, disassembly, or clearance of cellular packages of RNA and proteins known as RNA granules. Our research focus is to investigate the role of RNA granules in regulating gene activity, explore how granules are assembled and disassembled, and investigate how these types of defects in RNA metabolism can cause neurodegenerative diseases.
Postdoctoral Fellow, Van Damme Lab
Employer: VIBPrincipal Investigator: Veterans Health Administration
Location: Leuven, Belgium
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: May 8, 2017
Description:
The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains.
Postdoctoral Fellow, Vande Velde Lab
Employer: CRCHUMPrincipal Investigator: Veterans Health Administration
Location: Montréal, Canada
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: June 20, 2017
Description:
Dr. Christine Vande Velde is looking to recruit a PostDoc to her laboratory located at the CRCHUM facility, a research center affiliated with the Université de Montréal and located in Downtown Montreal.
Postdoctoral Fellow, Verfaillie Lab
Employer: KU LeuvenPrincipal Investigator: Veterans Health Administration
Location: Leuven, Belgium
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: October 31, 2017
Description:
The lab of Dr. Verfaillie at the Stem Cell Institute Leuven is looking for a postdoctoral fellow with expertise in: The lab of Dr. Verfaillie at the Stem Cell Institute at KU Leuven is recruiting an outstanding postdoctoral fellow highly versed in pluripotent stem cell biology techniques, including multicellular organoid cultures either in 2.5D and in 3D in suspension or in hydrogel based static or bioreactor cultures. The goal is to create lifelike small brain tissues, including the blood brain barrier or the cortex, that can be used as disease models in a dish, to study, Alzheimer’s, Parkinson, frontotemporal dementia or ALS available from teams at KU Leuven and the Flemish Institute of Technology (VIB), using patient iPSC and their isogenic counterparts. The technology should enable gaining superior insights in mature brain features such as defined connectivity and neuron-glia interactions, neurodegeneration phenotypes, and identification of druggable phenotypes.
Postdoctoral Fellow, Ward Lab
Employer: NINDSPrincipal Investigator: Veterans Health Administration
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: September 19, 2017
Description:
A postdoctoral position in cell biology and neurodegenerative diseases is available in the lab of Dr. Michael Ward, National Institute of Neurological Disorders and Stroke (NINDS), Neurogenetics Branch, in Bethesda MD. The Ward lab utilizes human iPSC-derived neurons to study basic mechanisms of neurodegeneration. By combining forward-genetics, proteomics, and molecular/biochemical techniques, we seek to identify converging disease pathways that underlie inherited neurodegenerative diseases. In parallel, we pursue complimentary drug discovery approaches using ultra high-content small molecule screens with colleagues in the National Center for Advancing Translational Sciences (NCATS).
Postdoctoral Fellow, Wolozin Lab
Employer: Boston UniversityPrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: January 31, 2018
Description:
A NIH funded postdoctoral position is available in the laboratory of Benjamin Wolozin to study the role of RNA binding proteins, RNA metabolism and RNA granules in the pathophysiology of neurodegenerative diseases. The postdoctoral fellow will investigate how these processes are regulated, and how dysfunction contributes to disease. The studies will use phase separation biology, cell biology, imaging, optogenetics, proteomics, systems biology and RNAseq. The studies will take advantage of our finding that reducing the RNA binding protein TIA1 delays progression in a mouse model of tauopathy (Apicco, et al, Nature Neuro., 21(1):72-80, PMID: 29273772.)
Postdoctoral Fellow, Xia Lab
Employer: University of Central FloridaPrincipal Investigator: Veterans Health Administration
Location: Orlando, FL
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: November 8, 2017
Description:
A research lab at the University of Central Florida Medical College invites you to apply for post-doctoral associate position. Research in the lab is focused on the genetic and molecular mechanisms of neurodegeneration in amyotrophic lateral sclerosis and Parkinson’s disease. Our team has published our findings in Acta Neuropath, EMBO J, the Journal of Clinical Investigation, PLoS Genetics, and PNAS. Post-doctors being recruited will help validate the pathogenic role of genetic mutations newly discovered in the lab using cell culture and animal models. The research lab is located at the UCF Burnett School of Biomedical Sciences at the Lake Nona campus. Researchers who have recently obtained their PhD degrees and seek to further develop their academic career are encouraged to apply for the positions. Please email your CV to Dr. Xugang Xia at xugang.xia@ucf.edu
Employer: University of Central Florida
Location: Orlando, FL
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: November 8th, 2017
Postdoctoral Fellow, Xu Lab
Employer: University of Massachusetts Medical SchoolPrincipal Investigator: Veterans Health Administration
Location: Worcester, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: March 5, 2017
Description:
A postdoctoral position is available in Zuoshang Xu’s laboratory to study mechanism of motor neuron degeneration in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease.
Postdoctoral Fellow, Yang Lab
Employer: Tufts University School of MedicinePrincipal Investigator: Veterans Health Administration
Location: Boston, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: January 18, 2017
Description:
The Yang lab also studies pathogenic roles of astrocyte dysfunction in neurological diseases/disorders, such as fragile x syndrome (FXS) and amyotrophic lateral sclerosis (ALS). The lab employs novel genetically modified mouse tools, in combination with primary astrocyte and neuronal cultures, imaging, electrophysiological and biochemical/molecular techniques. The candidate must be able to handle rodents and are familiar with biochemical techniques and prior knowledge of neurodegenerative diseases is desirable. It is expected that the candidate should have a recent PhD (less than 2 years) in Neuroscience/Genetics/Cell Biology/Biochemistry or equivalent and is able to communicate well with others. To apply, please send your CV (via e-mail) including all past education and training, a brief description of research interests, list of publications and other scientific activities as well as names and e-mail addresses of three references to Dr. Yongjie Yang at: Yongjie.yang@tufts.edu.
Employer: Tufts University School of Medicine
Location: Boston, MA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: January 18th, 2017
Postdoctoral Fellow, Zhang Lab
Employer: University of WisconsinPrincipal Investigator: Veterans Health Administration
Location: Madison, WI
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 14, 2018
Description:
Postdoctoral positions are available at the University of Wisconsin-Madison to study neural stem/progenitor cell self-renewal /reprogramming and functional dissection / therapeutic implication of human neural cells in neurological disorders. PhD or equivalent in cell / molecular / developmental biology, neuroscience, or chemistry is required. Experiences in electrophysiology, small animal microsurgery, genome editing, or 3D printing are highly desirable. Compensation follows the NIH standard. The Zhang laboratory is a leading group studying neural specification of human pluripotent stem cells and application of stem cells in developing therapeutics for neurological diseases (e.g., Cell Stem Cell, 2014, 2015, 2016, Nature Biotechnology, 2016, Nature Medicine, 2016, Nature Communication, 2017, Stem Cell Reports 2017/18). It is located in the NIH-sponsored Waisman Center that is dedicated for studying human development, developmental disability, and neurodegenerative diseases. Candidates enthusiastic in pursuing regenerative sciences are welcome to join this vibrant group in the beautiful city of Madison.
Employer: University of Wisconsin
Location: Madison, WI
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: May 14th, 2018
Postdoctoral Fellow, Zhang Lab
Employer: University of Texas-SouthwesternPrincipal Investigator: Veterans Health Administration
Location: Dallas, TX
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: November 30, 2017
Description:
Two fully funded postdoctoral positions are immediately available, in the laboratory of Chun-Li Zhang, Ph.D., Department of Molecular Biology. One is to examine human neurodegenerative disease by using human embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and age-matched directly reprogrammed neurons. The focus is on molecular and cellular mechanisms underlying degeneration and the identification of chemical compounds promoting neuronal survival and function.
Postdoctoral Position
Employer: Cornell UniversityPrincipal Investigator: Veterans Health Administration
Location: Ithaca, NY
Sector: Academia
Degree Required: PhD, MD, PhD/MD
Conditions: ALS, FTD
Posted on: May 27, 2016
Description:
A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply. Please visit http://hu.wicmb.cornell.edu/ for more details and send your CV and 3 letters of references.
Employer: Cornell University
Principal investigator: Fenghua Hu
Location: Ithaca, NY
Sector: Academia
Degree required: PhD, MD, PhD/MD
Conditions: ALS, FTD
Job posted: May 27th, 2016
Postdoctoral Position
Employer: Cedar-Sinai Regenerative Medicine InstitutePrincipal Investigator: Veterans Health Administration
Location: Los Angeles, CA
Sector: Academia
Conditions: ALS
Posted on: Sep 11, 2016
Description:
The Cedars-Sinai Regenerative Medicine Institute has a Research Postdoctoral position available to study the molecular mechanisms of neurodegeneration, with particular focus on axon degeneration in inherited peripheral nerve diseases, including demyelinating peripheral nerve disease. Candidate must be experienced with performing techniques ranging from neuronal and stem cell culture, molecular biology and bioinformatics (RNA-seq, exome seq), biochemistry and cell biology.
Postdoctoral Position
Employer: Gladstone InstitutesPrincipal Investigator: Veterans Health Administration
Location: San Francisco, CA
Sector: Academia
Degree Required: PhD
Conditions: ALS, NDG
Posted on: Jun 3, 2016
Description:
The Postdoctoral Scholar position in the laboratory of Steven Finkbeiner involves a collaboration between Verily Life Sciences and will focus on developing models and assays for investigating mechanisms of neurodegeneration. The ideal candidate will have experience in human iPSC culture and neuron differentiation, a strong molecular biology background and analytic skills with experience of imaging analysis software and statistical analysis programs.
Postdoctoral Position
Employer: University of Massachusetts Medical SchoolPrincipal Investigator: Veterans Health Administration
Location: Worcester, MA
Sector: Academia
Degree Required: PhD
Conditions: ALS, NDG
Posted on: Feb 12, 2016
Description:
The focus of the laboratory is to study gene therapy approaches for the treatment of neurodegenerative diseases such as lysosomal storage diseases (GM1-gangliosidosis and Tay-Sachs disease), amyotrophic lateral sclerosis (ALS), Huntington’s disease, and brain tumors. The position requires attention to detail, good communication, strong skills in experimental design and troubleshooting, an ability to work independently. The focus of this position is to investigate systemic AAV gene therapy approaches for Tay-Sachs disease using novel AAV capsids and vector designs.
Employer: University of Massachusetts Medical School
Principal investigator: Miguel Esteves
Location: Worcester, MA
Sector: Academia
Degree required: PhD
Conditions: ALS, NDG
Job posted: February 12th, 2016
Postdoctoral Position – Neurodegenerative Disease
Employer: Washington UniversityPrincipal Investigator: Veterans Health Administration
Location: St. Louis, MO
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: June 2, 2016
Description:
The primary responsibility of the post-doctoral fellow will be to conceive, design, and analyze studies pertaining to the effect of neurodegenerative disease on structural (e.g., volumetric imaging and diffusion tensor imaging [DTI]) and functional (e.g., blood oxygen level dependent [BOLD] imaging and arterial spin labeling [ASL]) brain organization. Anticipated activities entail development and implementation of new analytic strategies to facilitate understanding of disease in the human brain, integration of large multi-modal imaging datasets, and analysis of the relationship between brain imaging markers and cognition or clinical status. Strong written communication skills are required. Attention to detail, organizational capability, and the ability to handle multiple concurrent tasks are essential. The post-doctoral fellow is expected to be able to work independently as well as part of a team in a fast paced environment.
Postdoctoral Position – Center fro Bionic Medicine
Employer: Rehabilitation Institute of ChicagoPrincipal Investigator: Veterans Health Administration
Location: Chicago, IL
Sector: Academia
Conditions: ALS
Posted on: August 16, 2016
Description:
The Single Motor Unit Laboratory (SMPP) strives to understand how the nervous system controls individual motor units within a muscle so as to enable the generation of muscle force. Seeks to investigate the role of intrinsic properties of motoneurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS). The PostDoc Fellow will be responsible for the design, execution and interpretation of experiments within a laboratory team environment and a larger laboratory research program of engineers, physical therapists and neuroscientists focused on sensory motor performance and rehabilitation within a major, nationally leading Academic Rehabilitation Hospital.
Postdoctoral Position – Fenghua Hu Lab
Employer: Cornell UniversityPrincipal Investigator: Veterans Health Administration
Location: Ithaca, NY
Sector: Academia
Degree Required: PhD, MD, PhD/MD
Conditions: ALS, FTD
Posted on: October 27, 2016
Description:
A postdoctoral position is available at Cornell University to study lysosomal dysfunction and neurodegeneration in ALS and FTLD. Highly motivated individuals with a strong background in cell biology or mouse genetics and an interest in neurodegenerative diseases are encouraged to apply.
Postdoctoral Position Sensory Motor Performance
Employer: Rehabilitation Institute of ChicagoPrincipal Investigator: Université de Montréal
Location: Chicago, IL
Sector: Academia
Conditions: ALS
Posted on: Jul 12, 2016
Description:
The Single Motor Unit Laboratory (SMPP) at the Rehabilitation Institute of Chicago (RIC) seeks to investigate the role of intrinsic properties of motor neurons that innervate relevant muscle fiber populations in providing such control under normal conditions and following such illnesses as stroke, spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS). The PostDoc Fellow will be responsible for the design, execution and interpretation of experiments within a laboratory team environment and a larger laboratory research program of engineers, physical therapists and neuroscientists focused on sensory motor performance and rehabilitation within a major, nationally leading Academic Rehabilitation Hospital.
Postdoctoral Position in Neurodegeneration
Employer: Cedars Sinai Regenerative Medicine InstitutePrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: PhD, MD, DVM
Conditions: NDG
Posted on: May 11, 2016
Description:
The Cedars-Sinai Regenerative Medicine Institute has a Research Postdoctoral position available to study the molecular mechanisms of neurodegeneration, with particular focus on axon degeneration in inherited peripheral nerve diseases. The primary focus of the candidate will be working with patient derived iPS cell lines, genetically engineering them using CRISPR technology, molecular and genomic characterization including exome sequencing, and differentiating them into motor neurons and Schwann cells to investigate cell replacement therapies for patients.
Postdoctoral Position in Neurodegeneration Research and RNA Biology
Employer: Johns Hopkins University School of MedicinePrincipal Investigator: Université de Montréal
Location: Baltimore, MD
Sector: Academia
Degree Required: PhD
Conditions: ALS,
Posted on: May 5, 2016
Description:
Postdoctoral opportunities are available in Dr. Shuying Sun’s laboratory at Johns Hopkins University School of Medicine. The Sun lab is interested in deciphering the RNA processing pathways altered by the ALS-causative mutants, identifying inhibitors of neuron toxic factors using various high-throughput screening platforms, and developing novelCRISPR technique-based therapeutic strategies.
Employer: Johns Hopkins University School of Medicine
Principal investigator: Shuying Sun
Location: Baltimore, MD
Sector: Academia
Degree required: PhD
Conditions: ALS,
Job posted: May 5th, 2016
Postdoctoral Position – Lewcock Lab
Employer: DenaliPrincipal Investigator: Université de Montréal
Location: South San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: Sep 03, 2016
Description:
Joe Lewcock’s Lab at Denali Therapeutics is seeking to recruit Postdoctoral Scientists to interrogate the molecular and cellular pathways underlying neurodegenerative diseases, with the ultimate goal of identifying new drug targets. Candidates should have proficiency in a broad range of molecular genetic, biochemical, and cellular techniques including: molecular cloning, transfection, RNA interference, Western blotting, immunofluorescence and/or live imaging techniques, and quantitative image analysis.
Postdoctoral Position, College of Veterinary Medicine
Employer: University of TennesseePrincipal Investigator: Université de Montréal
Location: Knoxville, TN
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: May 26, 2016
Description:
A Post-Doctoral Research Associate position is available immediately to study the mechanisms underlying the abnormal amyloid beta-peptide formation and neuronal cells death observed in the central nervous system (CNS) of Alzheimer’s disease and amyotrophic lateral sclerosis (ALS) patients using both animal models and cultured cell systems.
Postdoctoral Position- Pandey Lab
Employer: University of Pittsburgh School of MedicinePrincipal Investigator: Université de Montréal
Location: Pittsburgh, PA
Sector: Academia
Degree Required: PhD
Conditions: ALS, NDG
Posted on: Apr 22, 2016
Description:
A Postdoctoral Researcher position is available immediately at the Children’s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, to study the molecular mechanisms of human neurodegenerative diseases such as ALS and polyglutamine expansion diseases. The candidate will work with mammalian neuronal culture and drosophila models of ALS and other related human neurodegenerative diseases.
Postdoctoral Positions – Institute for Genomic Medicine
Employer: Columbia UniversityPrincipal Investigator: Université de Montréal
Location: New York, NY
Sector: Academia
Conditions: ALS
Posted on: August 16, 2016
Description:
Multiple postdoctoral positions in Precision Medicine in Columbia’s Institute for Genomic Medicine.
Postdoctoral Positions in Neurodegenerative Disease
Employer: University of FloridaPrincipal Investigator: Université de Montréal
Location: Gainesville, FL
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD, NDG
Posted on: May 11, 2016
Description:
Various postdoc opportunities in ALS, FTD, and neurodegeneration research are available through several labs at University of Florida’s Center for Translational Research in Neurodegenerative Disease, including:
Principal Investigator, Laboratory of Neuronal Cell Biology
Employer: BiogenPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD or MD/PhD
Conditions: NDG
Posted on: March 9, 2017
Description:
As Principal Investigator for the Laboratory of Neuronal Cell Biology (LNCB), he or she will be:
Principal Research Associate, Neuroscience
Employer: Genzyme (Sanofi)Principal Investigator: Université de Montréal
Location: Framingham, MA
Sector: Industry
Conditions: ALS
Posted on: August 1, 2016
Description:
We are seeking a motivated Principal Research Associate to join a team of neuroscientists dedicated to developing novel therapies for diseases of the nervous system. The primary responsibility of this individual will be to validate new therapeutic targets for the treatment of amyotrophic lateral sclerosis (ALS) and additional CNS indications under consideration. The successful candidate will have experience with a variety of in vivo and in vitro experimental techniques.
Principal Scientist
Employer: Astellas PharmaPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: May 16, 2018
Description:
Purpose:
Principal Scientist, Blood-Brain Barrier (BBB) Transport Technologies
Employer: BiogenPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: April 13, 2018
Description:
We are seeking an experienced scientist to join Biogen’s Biologics Drug Discovery Team, and contribute to our mission to design, optimize, and develop important protein therapeutics to improve the lives of patients with neurodegenerative disease. In this role, you will jointly lead a cross-functional effort to identify and validate novel methods for enhancing delivery of protein biologics to the central nervous system (CNS).
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: April 13th, 2018
Principal Scientist, Neuroscience
Employer: AmgenPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: BS, MS or PhD
Conditions: ALS
Posted on: December 11, 2017
Description:
We are seeking a Research Principal Scientist to join a vibrant and growing group currently focusing on developing new and effective therapeutics for neurodegenerative diseases, migraine and neuropathic pain. This position is within the Neuroscience Therapeutic Area, a key component of the Discovery Research unit at Amgen’s site in Cambridge, MA. The Principal Scientist will focus on in vivo model test systems and the development and validation of mechanism based pharmacodynamic measures supporting characterization and pipeline advancement of novel CNS therapeutics.
Employer: Amgen
Location: Cambridge, MA
Sector: Industry
Degree required: BS, MS or PhD
Conditions: ALS
Job posted: December 11th, 2017
Principal Scientist, Neuroscience, In Vivo Pharmacology
Employer: MerckPrincipal Investigator: Université de Montréal
Location: West Point, PA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: January 11, 2018
Description:
The successful candidate will be a member of the West Point Pharmacology Department, a department that provides in vitro and in vivo pharmacology solutions to support a wide variety of neuroscience, infectious disease, and cardio-metabolic programs.
Project Manager of Therapeutics
Employer: California Institute for Regenerative Medicine (CIRM)Principal Investigator: Université de Montréal
Location: Oakland, CA
Sector: NON-PROFIT AND GOVERNMENT
Posted on: Sep 03, 2016
Description:
California Institute for Regenerative Medicine (CIRM) is looking to hire a talented individual to join the Therapeutics Team as a Project Manager. The mission of the CIRM Therapeutics Team is to recruit and enable the development of innovative clinical stage regenerative medicine / cell therapy programs to address the unmet medical needs of patients. The Project Manager reports to the VP of Therapeutics and will coordinate operations of the Therapeutics Team in order to accomplish this mission. The Project Manager will manage the development and execution of project team strategy and will optimize the team’s effectiveness in achieving project objectives in alignment with the stated quarterly and annual goals of that team.
Research Assistant
Employer: Rockefeller UniversityPrincipal Investigator: Université de Montréal
Location: New York, NY
Sector: Academia
Degree Required: BA or BS
Conditions: NDG
Posted on: April 21, 2018
Description:
The Rockefeller University seeks a Research Assistant to join Laboratory of Molecular Biology. The Research Assistant will contribute to a project examining the molecular mechanisms of neurodegenerative and psychiatric disorders. The Research Assistant will be responsible for performing molecular techniques, including TRAP, RNA-seq, in situ hybridization, and immunohistochemistry, to examine cell type specific gene expression profiles in the mouse brain. Will complete rodent surgeries, behavioral assays, and functional imaging of brain immunohistochemistry. Will be responsible for maintaining genetically altered mouse lines and completing other routine laboratory duties as needed.
Research Assistant, Engle Lab
Employer: Boston Children's HospitalPrincipal Investigator: Université de Montréal
Location: Boston, MA
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: March 7, 2018
Description:
This is an Exciting opportunity at Boston Children’s Hospital to support a cutting edge developmental neuroscience laboratory using emerging techniques in single cell RNA sequencing (scRNAseq) to understand the molecular mechanisms of motor neuron diseases, including eye movement disorders and amyotrophic lateral sclerosis (ALS). (http://www.childrenshospital.org/research-and-innovation/research/labs/engle-laboratory).
Employer: Boston Children's Hospital
Location: Boston, MA
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: March 7th, 2018
Research Assistant, Jackrel Lab
Employer: Washington UniversityPrincipal Investigator: Université de Montréal
Location: Saint Louis, MO
Sector: Academia
Degree Required: BS
Conditions: NDG
Posted on: January 5, 2018
Description:
The Jackrel Lab is interested in hiring a research specialist. We are looking for recent graduates in Chemistry, Biochemistry, Biophysics, Cell Biology, Genetics, Neuroscience, and related areas. Applicants with more senior experience will also be considered. Responsibilities will include driving an independent research project and assisting in the general organization and running of the lab. We study protein folding and misfolding, and how protein misfolding can lead to neurodegenerative disease. For more information about our research interests, please visit: https://sites.wustl.edu/jackrel/
Employer: Washington University
Location: Saint Louis, MO
Sector: Academia
Degree required: BS
Conditions: NDG
Job posted: January 5th, 2018
Research Assistant, Neurodegenerative Disease
Employer: Karolinska InstitutetPrincipal Investigator: Université de Montréal
Location: Stockholm, Sweden
Sector: Academia
Degree Required: A university medical degree
Conditions: NDG
Posted on: June 14, 2017
Description:
As a research assistant, the successful candidate will work with protein analysis (Western blot), histological analysis (immunofluorescence, in situ hybridization), analysis of data from in vivo neurotransmitter recordings (glutamate, dopamine recordings) and cytological analysis (immunofluorescence). The source of these samples will be from cell lines, animal models and human samples. The applicant will work close with patients and perform skin biopsies, blood sampling and lumbar punctures to obtain working material. The applicant will be responsible for analyzing these samples according to their respective protocols and the analyses are documented and stored in structured and easy to follow way.
Research Assistant, Spillantini Lab
Employer: University of CambridgePrincipal Investigator: Université de Montréal
Location: Cambridge, England
Sector: Academia
Degree Required: BS
Conditions: NDG
Posted on: October 26, 2017
Description:
Applications are invited for a Research Assistant role to work on a collaborative project between the groups of Professor David Klenerman and Professor Maria Grazia Spillantini to study the molecular basis of neurodegenerative disease.
Research Associate
Employer: NuredisPrincipal Investigator: Université de Montréal
Location: Menlo Park, CA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 23, 2017
Description:
Nuredis, Inc. discovers and develops small molecule therapies for a group of inherited neurodegenerative and neuromuscular diseases, aiming to treat the cause of disease rather than just managing symptoms. Nuredis was founded in 2016 based on technology licensed from Stanford, with facilities in Menlo Park. We are currently seeking self-driven, intelligent individuals to add their complementary talents to our highly-motivated team.
Research Associate
Employer: New York Genome CenterPrincipal Investigator: Université de Montréal
Location: New York, NY
Sector: Academia
Degree Required: BS or MS
Conditions: ALS
Posted on: April 9
Description:
The Center for Genomics of Neurodegenerative Disease at the New York Genome Center is looking for a well-organized, methodical, and highly motivated Research Associate. This is an exciting opportunity to become part of a dynamic group that is investigating the interactions between motor neurons and glial cells in ALS pathology using hiPSC cell-based models combined with next generation sequencing and CRISPR technology. Our particular focus is to examine the transcriptional, translational, and functional impact of causative ALS mutations in a cell type specific manner. The individual will interface with the Director and key scientific staff to assume responsibility for hiPSC culture, differentiation, functional assays, and RNA harvesting for NGS. The Research Associate will be part of an interdisciplinary team working in a fast-paced environment.
Research Associate
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Francisco, CA
Sector: Academia
Degree Required: BA or BS
Conditions: FTD
Posted on: March 23, 2017
Description:
The position is for a full time Staff Research Associate to assist the PI in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus. The Staff Research Associate is expected to be open to learning new methods. One year of relevant laboratory experience including laboratory histology (embedding, cutting, immunohistochemistry, and coverslipping).The position represents an excellent opportunity to further basic laboratory and research skills in a dynamic clinical neuroscience environment. The successful individual will be an energetic, team player, self-directed learner with a keen interest in research.
Employer: University of California
Location: San Francisco, CA
Sector: Academia
Degree required: BA or BS
Conditions: FTD
Job posted: March 23rd, 2017
Research Associate
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Francisco, CA
Sector: Academia
Degree Required: BA or BS
Conditions: FTD
Posted on: June 22, 2017
Description:
Under the supervision of the Principal Investigator, the Staff Research Associate II (SRA II) will assist in the performance of behavioral testing and in the analysis of behavioral and neuroimaging data to support research on the neural bases of decision-making in healthy individuals with a family history of frontotemporal dementia. Specific techniques utilized in these studies will include online computer-based testing, task-based functional MRI, psychophysiology, voxel-based morphometry, functional connectivity, and computational modeling of behavior.
Research Associate – Taylor Lab
Employer: Howard Hughes Medical Institute (HHMI)Principal Investigator: Université de Montréal
Location: Memphis, TN
Sector: Academia
Conditions: ALS, FTD, NDG
Posted on: August 16, 2016
Description:
The Howard Hughes Medical Institute is seeking a highly motivated Research Specialist to join Dr. J. Paul Taylor’s group at St. Jude Children’s Research Hospital. The primary focus of this position will be the use of Drosophila melanogaster as a tool to investigate the molecular genetics of neurological diseases.
Research Associate II
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BS
Conditions: NDG
Posted on: April 2, 2017
Description:
Incumbent will assist with new metabolic targets to treat neurodegenerative disease. Under general supervision, assist the principal investigator and laboratory members in developing novel techniques and models to study the intersection between mitochondrial metabolism and neural physiology. Research duties will include assisting with animal handling, tissue harvest, dissections, and primary neural cell preparations. Additional responsibilities will include biochemical assays (immunoblot analysis ,subcellular fractionation), molecular biology (qRT-PCR and genetic manipulation of cells with siRNA, viral vectors, or CRISPR technology), and specialized metabolic assays (Seahorse XF analysis, plate-based enzymatic assays). Preparation of samples for high-content imaging or mass spectrometry analysis will also be required. Further duties will include general lab maintenance responsibilities, such as organization and management of supplies, chemical reagents, and animals.
Research Associate II, Svendsen Lab
Employer: Cedars-SinaiPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: April 4, 2018
Description:
The Svendsen Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for personnel to join our dynamic group. The ideal incumbent should have experience in managing and analysis of large datasets using programming languages such as Python and R, and an interest in working hands on with stem cells and organ-on-chip technology with a focus on research in neurodegenerative diseases (Brain-on-Chip). Ideal candidate will also have experience in machine learning approaches for use in automation of laboratory equipment and analysis of complex bioinformatic datasets. Working with the P1 and scientists, the Research Associate II (RA11) performs a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research, including the Brain-on-Chip program. RAII is responsible for the generation and curation of acquired data, implementation of analysis programs, and generation of scripts to assists in laboratory activities and research aims. RAH is responsible for general laboratory activities including maintenance of reagents, ordering and stocking of supplies. RA11 keeps accurate and detailed records of experiments and results. RAH assists in the operation of specialized equipment and machinery, including the culture of human stem cell derived tissues. Observes safety standards and procedures. This position may include supervisory responsibilities. Daily Duties will include the following: – Performs a variety of routine laboratory tasks and procedures. – Works with laboratory staff to develop and implement analysis frameworks for use in biomarker and therapeutic target discovery – Keeps accurate and detailed project records of experiments and results. – Maintains lab equipment and related records. – Transports, processes and logs samples. – Maintains computer database with relevant information – implements scripts for the analysis of complex imaging and multi-omic analysis datasets. – Performs lab maintenance duties, including glassware cleaning and sterilization, – Maintains stocks of general lab materials, and places orders for lab equipment and supplies. – Assists new students and fellows at the laboratory. – Assists in the operation of specialized equipment and machinery. – Observes and complies with safety standards arid procedures. – Histology and Microscopy – Sectioning of tissue specimens – Staining of tissue specimens to include special stains and INC. Additional Information: Scheduling flexibility including evening, weekend and holiday rotation commitment is required. Travel may be required.
Employer: Cedars-Sinai
Location: Los Angeles, CA
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: April 4th, 2018
Research Associate II/III
Employer: RegeneronPrincipal Investigator: Université de Montréal
Location: Tarrytown, NY
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: May 16, 2017
Description:
Summary
Research Associate, Baloh Lab
Employer: Cedars Sinai Medical CenterPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BA, BS or MS
Conditions: ALS
Posted on: January 06, 2017
Description:
Under the direction of the PI or research staff, the Research Associate will help us achieve our research goals by performing and managing tissue culture projects in the lab. The primary focus will be human fibroblasts and stem cell culture, but primary neuron culture from animal models will also be performed.
Employer: Cedars Sinai Medical Center
Location: Los Angeles, CA
Sector: Academia
Degree required: BA, BS or MS
Conditions: ALS
Job posted: January 6th, 2017
Research Associate, Fraenkel Lab
Employer: MITPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: March 20, 2017
Description:
The research group of Professor Ernest Fraenkel seeks a talented scientist to participate in an unprecedented study of the neurodegenerative disease ALS. Working with researchers at clinical and academic institutions across the United States, we are gathering data on approximately 1,000 ALS patients and controls. Induced pluripotent stem cell (iPSC) lines are being derived from each individual and these are being used to generate motor neurons for a wide range of omic studies. Our collaboration seeks to identify different subtypes of the disease, identify correlations between molecular pathways and clinical symptoms, and propose therapeutic strategies.
Research Associate, Gao Lab
Employer: University of Massachusetts Medical SchoolPrincipal Investigator: Université de Montréal
Location: Worcester, MA
Sector: Academia
Degree Required: BS
Conditions: FTD
Posted on: August 7, 2017
Description:
A Research Associate position in the laboratory of Dr. Fen-Biao Gao at the Department of Neurology is available to help study frontotemporal dementia using induced pluripotent stem cells (iPSCs). Candidates with substantial research experiences in molecular biology (such as western blot, cloning etc.) and cell biology (such as stem cell culture and differentiation, or mammalian cell cultures in general) are encouraged to apply. Candidates with PhD or MD degrees will be considered as well.
Employer: University of Massachusetts Medical School
Location: Worcester, MA
Sector: Academia
Degree required: BS
Conditions: FTD
Job posted: August 7th, 2017
Research Associate, Grinberg Lab
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Francisco, CA
Sector: Academia
Degree Required: BA or BS
Conditions: FTD
Posted on: November 22, 2017
Description:
The Staff Research Associate II (SRA II) position is for a full time lab technician (Research Assistant) to assist the Principal Investigator (PI) in neuropathology research that investigates the pathogenesis of Alzheimer’s disease, frontotemporal dementia, and related disorders at UCSF Mission bay campus (see http://grinberglab.ucsf.edu).
Research Associate, Medicinal Chemistry
Employer: CytokineticsPrincipal Investigator: Université de Montréal
Location: South San Francisco, CA
Sector: Industry
Degree Required: BS, MS
Conditions: NDG
Posted on: May 5, 2016
Description:
Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators as potential treatments for debilitating diseases in which muscle performance is compromised and/or deteriorating. With an unmatched understanding of muscle biology and mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to increase muscle function and contractility. Working collaboratively, Cytokinetics’ dedicated employees are focused on advancing novel mechanism therapeutics to dramatically improve the lives of patients. With purpose and passion, we have committed to make an important impact on serious medical illnesses.
Research Associate, Meyer Lab
Employer: Nationwide Children's HospitalPrincipal Investigator: Université de Montréal
Location: Columbus, OH
Sector: Academia
Degree Required: MS
Conditions: ALS
Posted on: February 16, 2018
Description:
They Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital. Our laboratory is looking for a highly motivated, Research Associate with minimum 2 years of experience to join our young and energetic team. The position does not require a background in gene therapy, but experience in performance of ELISAs and ELISpots, or previous experience working in a clinical laboratory, would be of advantage. The candidate will perform research experiments using patient samples, document and maintain exact records of experiments, prepare laboratory reports and assist with analyzing data.
Employer: Nationwide Children's Hospital
Location: Columbus, OH
Sector: Academia
Degree required: MS
Conditions: ALS
Job posted: February 16th, 2018
Research Associate, Neuro-Muscular Group
Employer: CRISPR TherapeuticsPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: BS
Conditions: NDG
Posted on: February 5, 2018
Description:
We are seeking a Research Associate to join the Neuro-Muscular group at CRISPR Therapeutics, an exciting, fast growing and well-financed company. The successful candidate will be an integral part of a team whose aim is to discover the next generation of genetic therapies for serious neurodegenerative diseases. The position requires enthusiasm, passion, attention to detail and a desire to create new medicines for patients.
Research Associate, Neuroimaging
Employer: University of Southern CaliforniaPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: October 9, 2017
Description:
One Research Associate position is currently available at the Laboratory of Neuro Imaging in the area of neuroimaging genetics, involving the development of algorithms for the identification of novel multimodal (imaging and genetic) feature combinations and models that explain such imaging-genetic interactions and facilitate diagnoses and prognoses in neuropsychiatric, neurodegenerative, and neurodevelopmental brain disorders. Additional responsibilities will be to train student researchers and interact with other laboratory assistants on common projects. Other key responsibilities will be documentation of procedures using word processing, data base and web-based applications, and supervised statistical analyses, figure and table preparation for various manuscripts and scientific presentations. The successful candidate will have a strong background in multimodal brain image analysis, large-scale genetic association study and statistical modeling. Knowledge of neuroanatomy and basic neuroscience, computer programming experience (working knowledge of Linux, Matlab, R, Python, C/C++, etc.) and excellent communication and writing skills are desired. Experience on database, bioinformatics, graphical models, dimensionality reduction, and machine learning is desirable.
Research Associate, Process Analytics
Employer: Voyager TherapeuticsPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: BS
Conditions: ALS
Posted on: January 8, 2018
Description:
Voyager Therapeutics is a gene therapy company developing life-changing treatments for severe neurological diseases. Voyager is committed to advancing the field of AAV (adeno-associated virus) gene therapy through innovation and investment in vector optimization and engineering, dosing techniques, as well as process development and production. The company’s pipeline is focused on severe neurological diseases in need of effective new therapies, including advanced Parkinson’s disease, a monogenic form of amyotrophic lateral sclerosis (ALS), Friedreich’s ataxia, Huntington’s disease, spinal muscular atrophy (SMA), frontotemporal dementia and Alzheimer’s disease and severe chronic pain.
Research Associate, Proteomics
Employer: Berg HealthPrincipal Investigator: Université de Montréal
Location: Framingham, MA
Sector: Industry
Degree Required: BS
Conditions: NDG
Posted on: February 28, 2017
Description:
Job description
Research Associate, Svendsen Lab
Employer: Cedars-Sinai Medical CenterPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: April 28, 2018
Description:
The Svendsen Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking personnel to join our dynamic group. The ideal incumbent should have experience in managing and analysis of large datasets using programming languages such as Python and R, and an interest in working hands on with stem cells and organ-on-chip technology with a focus on research in neurodegenerative diseases (Brain-on-Chip). Ideal candidate will also have experience in machine learning approaches for use in automation of laboratory equipment and analysis of complex bioinformatic datasets. Working with the PI and scientists, the Research Associate I (RA I) performs a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research, including the Brain-on-Chip program. RA I is responsible for the generation and curation of acquired data, implementation of analysis programs, and generation of scripts to assists in laboratory activities and research aims. RA I is responsible for general laboratory activities including maintenance of reagents, ordering and stocking of supplies. RA I keeps accurate and detailed records of experiments and results. RAH assists in the operation of specialized equipment and machinery, including the culture of human stem cell derived tissues. Observes safety standards and procedures. This position may include supervisory responsibilities. Daily Duties will include the following: – Performs a variety of routine laboratory tasks and procedures. – Works with laboratory staff to develop and implement analysis frameworks for use in biomarker and therapeutic target discovery – Keeps accurate and detailed project records of experiments and results. – Maintains lab equipment and related records. – Transports, processes and logs samples. – Maintains computer database with relevant information – implements scripts for the analysis of complex imaging and multi-omic analysis datasets. – Performs lab maintenance duties, including glassware cleaning and sterilization, – Maintains stocks of general lab materials, and places orders for lab equipment and supplies. – Assists new students and fellows at the laboratory. – Assists in the operation of specialized equipment and machinery. – Observes and complies with safety standards arid procedures. – Histology and Microscopy – Sectioning of tissue specimens – Staining of tissue specimens to include special stains and INC. Additional Information: Scheduling flexibility including evening, weekend and holiday rotation commitment is required. Travel may be required.
Employer: Cedars-Sinai Medical Center
Location: Los Angeles, CA
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: April 28th, 2018
Research Associate, Svendsen Lab
Employer: Cedars Sinai Medical CenterPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: September 21, 2017
Description:
The Svendsen Laboratory at the Cedars-Sinai Regenerative Medicine Institute is looking 1hr personnel to join our dynamic group. The incumbent should have an interest in the basic science of stem cells and neuroscience. By understanding how the cells grow and differentiate we will be able to produce a better cell for transplantation and develop techniques for disease modeling. The laboratory technician will, under the direction of the P1, lab manager and project scientist, assist in the conduct of research in Amyotrophic Lateral Sclerosis (ALS).
Research Associate, Thomsen Lab
Employer: Cedars Sinai Medical CenterPrincipal Investigator: Université de Montréal
Location: Los Angeles, CA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: July 10, 2017
Description:
Dr. Gretchen Thomsen’s Laboratory at the Cedars-Sinai Regenerative Medicine Institute is looking for personnel to join our dynamic group. The incumbent should have an interest in the basic science of stem cells and animal research. The laboratory technician will, under the direction of the PI and lab manager, assist in the conduct of research in amyotrophic lateral sclerosis (ALS) and traumatic brain injury (TBI).
Research Associate, ViTAL Consortium
Employer: University of UlsterPrincipal Investigator: Université de Montréal
Location: Belfast, Ireland
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: June 26, 2017
Description:
The postholder will join the ViTAL consortium of researchers working on Amyotrophic Lateral Sclerosis (ALS), funded by the charity TARGET-ALS. They will identify toxic elements that are secreted through exosomes in ALS, and determine their role in ALS. (Fixed-term until 30 June 2018)
Research Coordinator – UCSF Memory and Aging Center
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Francisco, CA
Sector: Academia
Conditions: FTD, NDG
Posted on: July 5, 2016
Description:
Under the supervision of a Clinical Research Supervisor or Principal Investigator (PI) at the UCSF Memory and Aging Center, the Research Coordinator will act as a study coordinator for clinical studies of normal aging, Alzheimer’s disease, Frontotemporal dementia and other forms of neurodegenerative disease, and may receive training and development to prepare and advance for journey-level work at the next level within the series.
Research Coordinator, Senior
Employer: University of PennsylvaniaPrincipal Investigator: Université de Montréal
Location: Philadelphia, PA
Sector: Academia
Degree Required: BS, MS, PhD
Conditions: ALS, FTD
Posted on: May 24, 2016
Description:
We are seeking a coordinator for a multi-site consortium using a novel approach to neuroimaging of neurodegenerative diseases. The lead site is Penn, and participating sites include Mayo Clinic, UCSF, MGH and Northwestern. All sites have specialized neuroimaging equipment, and we will be using advanced neuroimaging tools developed locally and in collaboration with the Human Connnectome Project (HCP) to analyze the acquired data. The successful candidate also will be responsible for managing the Penn site.
Employer: University of Pennsylvania
Location: Philadelphia, PA
Sector: Academia
Degree required: BS, MS, PhD
Conditions: ALS, FTD
Job posted: May 24th, 2016
Research Lead, CNS
Employer: Spark TherapeuticsPrincipal Investigator: Université de Montréal
Location: Philadelphia, PA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: March 2, 2018
Description:
The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for:
Research Programs Specialist
Employer: Weston Brain InstitutePrincipal Investigator: Université de Montréal
Location: London, UK
Sector: Other
Degree Required: PhD, MD
Conditions: ALS, FTD, NDG
Posted on: May 16, 2016
Description:
The Research Programs Specialist at the Weston Brain Institute will be responsible for developing the initiative’s scientific knowledge, running granting programs, and managing a portion of the Institute’s grant portfolio. Candidate should have research experience in one or more neurodegenerative diseases of aging, including ALS and FTD with a relevant PhD or MD. This position is located in London, UK and reports into the global operations in Toronto, Canada.
Research Scientist
Employer: AC ImmunePrincipal Investigator: Université de Montréal
Location: Lausanne, Switzerland
Sector: Industry
Degree Required: PhD
Conditions: ALS, FTD
Posted on: February 16, 2017
Description:
AC Immune is seeking a highly qualified Research Scientist to expand the
Research Scientist
Employer: InscopixPrincipal Investigator: Université de Montréal
Location: Palo Alto, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: October 12, 2017
Description:
Inscopix is looking for a talented neuroscientist with a strong background working with rodent models of neurodegenerative disease who is interested in pursuing groundbreaking brain science in a highly-motivating and fast-paced entrepreneurial environment. You will have unique opportunities to work in close collaboration with an interdisciplinary team of driven neuroscientists, physicists, engineers, and data scientists. If you are looking for an opportunity that immerses you in 21st century neuroscience, we want to hear from you!
Research Scientist
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Francisco, CA
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: June 23, 2017
Description:
The Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco (UCSF) is seeking a molecular/cell biologist to design, develop and validate novel tools for the study of neurodegenerative diseases. The director of the IND is Nobel Laureate Dr. Stanley Prusiner.
Research Scientist
Employer: University of BolognaPrincipal Investigator: Université de Montréal
Location: Bologna, Italy
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: May 10, 2017
Description:
The researcher will be devoted to the development of advanced techniques of in vivo Clinical Biochemistry, in particular metabolic (MR spectroscopy), microstructural and molecular (diffusion tensor imaging) and functional (fMRI) imaging, for the study of the central nervous system and neuromuscular system. The research activity will be applied to inflammatory, neurometabolic, neurodegenerative and neoplastic disorders, aimed to a) the identification of early diagnostic and prognostic markers and surrogate markers of treatment; b) the characterization of brain activations patterns; c) optimization of structural and functional connectivity analysis.
Employer: University of Bologna
Location: Bologna, Italy
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: May 10th, 2017
Research Scientist
Employer: BrainXellPrincipal Investigator: Université de Montréal
Location: Madison, WI
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: February 15, 2018
Description:
This scientist will lead an early-stage, hit-to-lead drug development project for Amyotrophic Lateral Sclerosis (ALS). Initially, he or she will conduct in-house experiments and work with external collaborators and CROs to establish a structure-activity relationship and guide the associated medicinal chemistry work. This individual will advance the project into the lead optimization phase, including ADME and in vivo efficacy. The requirements include a PhD in the biomedical sciences, competency in mammalian cell culture and assay development, background in neuroscience research, and industry experience in CNS drug development. Salary will be commensurate with experience; BrainXell offers full health and dental benefits.
Employer: BrainXell
Location: Madison, WI
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: February 15th, 2018
Research Scientist
Employer: University of CaliforniaPrincipal Investigator: Université de Montréal
Location: San Diego, CA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: May 2, 2017
Description:
Under general direction of the Principal Investigator (PI), leadership investigators, and project manager, the incumbent will undertake project activities under a CIRM award developing an embryonic stem cell-based therapy to treat Amyotrophic Lateral Sclerosis (ALS), making innovative and significant independent contributions pertaining to achievement of project milestones.
Research Scientist
Employer: NovartisPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: October 7, 2017
Description:
We are currently seeking a highly motivated, experienced scientist to join the stem cell group in the Neuroscience department to aid in target discovery and validation in the areas of psychiatry and neurodegeneration.
Research Scientist
Employer: NovartisPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 31, 2017
Description:
We are looking for an experienced BS or MS degreed research scientist to join the Neuroscience department. The candidate will play a hands-on role in a highly collaborative team responsible for research on neurodegenerative diseases. You will conceive, conduct, and analyze experiments to identify and evaluate compounds or biologics in various assays and cellular models. These include but are not limited to bioanalytical and biochemical assays, human ES/iPS derived neuronal models, and analysis of tissue samples.
Research Scientist
Employer: NovartisPrincipal Investigator: Université de Montréal
Location: Cambridge, MA
Sector: Industry
Conditions: NDG
Posted on: October 9, 2017
Description:
We are looking for an experienced research scientist to join the Neuroscience department. The scientist will assume a hands-on role in a team responsible for an early drug discovery project for a neurodegenerative disorder. The scientist will conceive, conduct, and analyze experiments to identify and validate novel targets and low molecular weight modulators. In vitro and ex vivo models, including hPSC-derived neuronal platforms, and other molecular and cell biology techniques, will be heavily utilized within projects. Excellent communication and teamwork will be critical.
Research Scientist
Employer: NovartisPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: September 8, 2017
Description:
We are seeking highly motivated individuals with BS/MS degrees to join a dynamic research group in the Neurosciences Division at Novartis Institutes for Biomedical Research in Cambridge, MA. The individual will conduct hands-on research directed towards understanding the molecular mechanisms underlying neurodegenerative disorders, and identify and evaluate small molecule compounds or biologics that target key pathogenic events in these diseases. Proficiency in the use of current molecular biology and biochemical techniques is expected. Extensive experience in mammalian cell culture, viral transduction techniques as well as gene knockdown technology and stable cell line generation are preferred. Candidates should have strong data analysis and communication skills. In addition to the above expertise candidates are expected to gain new skills based on evolving project needs and demands.
Employer: Novartis
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: September 8th, 2017
Research Scientist in Autoradiography
Employer: AC ImmunePrincipal Investigator: Institute of Molecular and Cell Biology
Location: Lausanne, Switzerland
Sector: Industry
Conditions: ALS, NDG
Posted on: Oct 13, 2016
Description:
AC Immune is seeking a highly qualified Research Scientist. The candidate must possess scientific background in structural biophysics and protein dynamics in neurodegenerative diseases and a clear record of accomplishment in an academic or a commercial setting. S/he will work on the discovery and characterization of PET radiotracers for the diagnosis of neurodegenerative disorders. Previous experience in neuroscience and neurodegenerative disorders, notably ALS and FTD along with TDP-43, is an advantage. S/he must have demonstrated their ability to make significant discoveries in an academic setting or bring a research product to a clinical stage.
Research Scientist, ALS
Employer: University of CaliforniaPrincipal Investigator: Institute of Molecular and Cell Biology
Location: San Diego, CA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: August 31, 2017
Description:
Under general direction of the Principal Investigator (PI), leadership investigators, and project manager, the incumbent will undertake project activities under a CIRM award developing an embryonic stem cell-based therapy to treat Amyotrophic Lateral Sclerosis (ALS), making innovative and significant independent contributions pertaining to achievement of project milestones.
Research Scientist, Neuroinflammation
Employer: Krembil Research InstitutePrincipal Investigator: Institute of Molecular and Cell Biology
Location: Toronto, Canada
Sector: Academia
Degree Required: PhD
Conditions: NDG
Posted on: June 8, 2017
Description:
The Krembil Research Institute at the University Health Network in Toronto Canada is seeking an early to mid career basic scientist in the area of neuroinflammation. Preference will be given to individuals with a research focus on the involvement of innate immunity, including the roles of immune mediators such as microglia and astrocytes, and their expressed cytokines and chemokines, in neurodegenerative diseases affecting the human CNS. The successful candidate will have a PhD or MD/PhD, postdoctoral experience and demonstrated research excellence. The successful candidate will be expected to qualify for an appointment at the Assistant or Associate Professor level (status only) in the appropriate department at the University of Toronto.
Research Scientist, Pathology
Employer: University of WashingtonPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Seattle, WA
Sector: Academia
Degree Required: MS
Conditions: NDG
Posted on: October 4, 2017
Description:
The Department of Pathology currently has an outstanding opportunity for a Research Scientist/Engineer 2. Under the general direction of the PI, this position provides comprehensive research to develop biomarkers for the diagnosis and staging of neurodegenerative diseases, and for the evaluation of potential disease modifying agents.
Research Scientist, Protein Sciences
Employer: Denali TherapeuticsPrincipal Investigator: Institute of Molecular and Cell Biology
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: October 10, 2017
Description:
We are seeking a Scientist with expertise in protein expression, purification and analytical characterization to contribute to our drug discovery efforts.
Research Scientist, Senior Research Scientist, Biomarkers
Employer: Denali TherapeuticsPrincipal Investigator: Institute of Molecular and Cell Biology
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: February 15, 2018
Description:
Denali Therapeutics is seeking to recruit a Research Scientist/Senior Research Scientist in support of the company’s growing translational biology and biomarker needs. This individual will work in close collaboration with colleagues in the In Vivo group, Research, Development Sciences, and Clinical Development to implement biomarker assays in support of preclinical target engagement studies. S/He would also contribute towards discovery/development of novel biomarkers for target engagement assessment and disease biology.
Employer: Denali Therapeutics
Location: San Francisco, CA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: February 15th, 2018
Research Specialist
Employer: Emory UniversityPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Atlanta, GA
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: May 15, 2018
Description:
A Lead Research Specialist position is available in the Center for Neurodegenerative Disease to join a dynamic research environment that uses a wide range of techniques and technologies to study neurodegenerative disease (e.g., Alzheimer’s disease, amyotrophic lateral sclerosis) pathogenesis. The successful applicant will be self-motivated and capable of working both independently and as a member of a team. Responsibilities will include assisting with the procurement and banking of human autopsy brain specimens and with distribution of tissue and biospecimens to investigators. He/she will also share responsibility for histological and immunohistochemical staining of human and rodent tissues. The successful applicant will be familiar with and train users in the proper use of shared laboratory equipment, and will share responsibility for maintaining the laboratory, including monitoring the storage and disposal of hazardous substances, ordering supplies, calibrating and performing routine repair and maintenance of equipment, interfacing with service personnel for equipment repairs, and maintaining and documenting laboratory safety standards. Upon hiring, the employee must complete the Laboratory Safety Training class and undergo immunization against potentially hazardous agents, as required by Emory University policy. Basic computer experience (Microsoft Word, Excel, etc.) and strong organizational and record-keeping skills are essential. Experience with Western blotting, confocal microscopy, tissue sectioning, histology and/or immunohistochemistry is highly desirable.
Employer: Emory University
Location: Atlanta, GA
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: May 15th, 2018
Research Specialist
Employer: University of PennsylvaniaPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Philadelphia, PA
Sector: Academia
Degree Required: BS
Conditions: ALS, FTD
Posted on: March 24, 2017
Description:
A full-time position is available in the laboratory of Dr. Corey McMillan in the Department of Neurology at the University of Pennsylvania. This laboratory focuses on translational neuroscience questions related to improving the diagnostic and prognostic biomarkers of related neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). We also explore genotype and phenotype relationships using a multimodal approach that integrates clinical, imaging, genetic, and biofluid datasets. Applicant responsibilities will include collection of psychometric and imaging data from patients with ALS and/or FTD, preliminary statistical analyses, database management, processing biofluid samples, and administrative coordination with consortia collaborators.
Employer: University of Pennsylvania
Location: Philadelphia, PA
Sector: Academia
Degree required: BS
Conditions: ALS, FTD
Job posted: March 24th, 2017
Research Specialist – Taylor Lab
Employer: Howard Hughes Medical Institute (HHMI)Principal Investigator: Institute of Molecular and Cell Biology
Location: Memphis, TN
Sector: Academia
Conditions: ALS, FTD, NDG
Posted on: August 16, 2016
Description:
The Howard Hughes Medical Institute is seeking a highly motivated Research Specialist to join Dr. J. Paul Taylor’s group at St. Jude Children’s Research Hospital. The primary focus of this position will be the use of Drosophila melanogaster as a tool to investigate the molecular genetics of neurological diseases.
Research Specialist, Biochemistry and Neurobiology
Employer: CalicoPrincipal Investigator: Institute of Molecular and Cell Biology
Location: South San Francisco, CA
Sector: Industry
Conditions: NDG
Posted on: Jul 12, 2016
Description:
Calico is inviting applications from biochemists/neurobiologists who are excited to work as part of a research team focused on identifying and targeting pathways involved in neurological diseases and aging. We are looking for a highly motivated and creative person who will focus on studying the underlying biology of protein aggregation and clearance in neurodegeneration and aging. This position will require independent work and the ability to develop and implement biochemical assays and cell-based assays in CNS cell types as well as deploy functional genomic platforms.
Research Specialist, Grossman Lab
Employer: University of PennsylvaniaPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Philadelphia, PA
Sector: Academia
Degree Required: BA or BS
Conditions: FTD
Posted on: September 26, 2017
Description:
A full-time position is available in the laboratory of Dr. Murray Grossman in the Department of Neurology at the University of Pennsylvania. This lab focuses on cognitive neuroscience and clinical questions relating to language, memory, and neurodegenerative disease (e.g., primary progressive aphasia, behavioral variant frontotemporal degeneration, Alzheimer’s). Applicant responsibilities will include the collection and analysis of PET scan data, and the collection and analysis of structural MRI data. This position will provide a strong foundation for individuals interested in continuing their education in graduate or medical school.
Employer: University of Pennsylvania
Location: Philadelphia, PA
Sector: Academia
Degree required: BA or BS
Conditions: FTD
Job posted: September 26th, 2017
Research Specialist, Plotkin Lab
Employer: University of PennsylvaniaPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Philadelphia, PA
Sector: Academia
Degree Required: BS
Conditions: FTD
Posted on: June 1, 2017
Description:
A full-time position is available in the lab of Alice Chen-Plotkin in the Department of Neurology at the University of Pennsylvania. Our lab researches neurodegenerative disease, with a particular focus on frontotemporal dementia and Parkinson’s disease. Projects range from studying the basic mechanisms of disease to finding and developing clinically useful tools such as biomarkers. Responsibilities for this position will include assistance with biochemical, molecular biological, and cell biological assays as needed to meet scientific goals. In addition, familiarity with analysis of large genetic datasets is preferred, including knowledge of statistical and computational methods (i.e. familiarity with linear/logistic regression, ability to use R or other statistical tools). All members of the lab are also expected to attend weekly lab meetings and to participate in the educational activities (e.g. journal club) of the lab.
Research Specialist, Southworth Lab
Employer: University of CaliforniaPrincipal Investigator: Institute of Molecular and Cell Biology
Location: San Francisco, CA
Sector: Academia
Degree Required: MS
Conditions: NDG
Posted on: December 8, 2017
Description:
The Institute for Neurodegenerative Diseases (IND) at UCSF, Mission Bay Campus is seeking a Specialist for full-time work to perform and manage research activities in biochemistry and structural biology. The position is in the laboratory of Dr. Daniel Southworth and will support research efforts using cryo-electron microscopy to determine 3D structures of important biological macromolecules associated with human neurodegenerative diseases. Highly motivated candidates capable of independent problem solving and teamwork are encouraged to apply. This position will be part of a collaborative environment with access to state-of-the-art facilities in the Sandler Neurosciences Building on the UCSF Mission Bay campus. A successful candidate will be hired at the Junior, Assistant, or Associate Specialist rank commensurate with experience and qualifications.
Research Study Coordinator
Employer: University of MiamiPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Miami, Florida
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: July 4, 2017
Description:
The Division of Neuromuscular Disorders is seeking a Research Support Coordinator to join a very active clinical research program with multiple ongoing research studies. The primary focus of the work will be on investigator-initiated research in the fields of amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG). The research support coordinator will work closely with clinical research coordinators, data manager, statistician, clinical staff and the Principal Investigator.
Employer: University of Miami
Location: Miami, Florida
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: July 4th, 2017
Research Technician
Employer: Massachusetts General HospitalPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Charlestown, MA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: April 27, 2018
Description:
The laboratory is seeking a motivated and enthusiastic candidate with experience in stem cell culture and molecular biology to support preclinical studies related to Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease) and pain. Working independently under the direction of the Principal Investigator, the research technician will assist in ongoing translational studies. The major responsibilities will include stem cell culture and differentiation, as well as general molecular biology techniques such as immunohistochemistry, RNA isolation and PCR to analyze the cells of interest. Additional work will include assistance with ordering, laboratory maintenance and animal husbandry.
Employer: Massachusetts General Hospital
Location: Charlestown, MA
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: April 27th, 2018
Research Technician
Employer: Massachusetts General HospitalPrincipal Investigator: Institute of Molecular and Cell Biology
Location: Charlestown, MA
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: July 9, 2017
Description:
The laboratory is seeking a motivated individual to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under the direction of the Principal Investigator, the research technician will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining and preparation of libraries for high throughput sequencing. The incumbent will also be responsible for handling patient samples and genetic testing of neurodegenerative conditions as part of a research project in collaboration with the ALS multidisciplinary clinic. Additional skills include maintenance of cell cultures, ordering necessary reagents to conduct experiments, and participation in joint upkeep of the lab. Experience in mouse handling and surgical procedures is preferred. The candidate will participate to the research activity of the lab and is expected to be fully engaged in the scientific projects, as well as participate to the scientific lab meetings. The individual must pay attention to details, can work independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team.
Employer: Massachusetts General Hospital
Location: Charlestown, MA
Sector: Academia
Degree required: BA or BS
Conditions: ALS
Job posted: July 9th, 2017
Research Technician
Employer: University of MichiganPrincipal Investigator: Fengua Hu
Location: Ann Arbor, MI
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: August 12, 2017
Description:
We are looking for individuals interested in a career in medicine to join our productive clinical research team for a 1-year term limited position (possible extension 1-3 years depending on funding).
Research Technician, Biffi Lab
Employer: Dana Farber Cancer InstitutePrincipal Investigator: Fengua Hu
Location: Boston, MA
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: November 29, 2016
Description:
Our lab aims at developing and testing a novel pharmacological platform, based on MRI/PET traceable nanoparticles targeted to activated microglia, as a therapeutic approach to track and modulate neuroinflammation in Amyotrophic Lateral Sclerosis. This position will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity. In general, this position will assist in the set up, operation and maintenance of laboratory instruments and equipment, monitoring experiments, making observations and calculating and recording results.
Employer: Dana Farber Cancer Institute
Location: Boston, MA
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: November 29th, 2016
Research Technician, Maniatis Lab
Employer: Columbia UniversityPrincipal Investigator: Fengua Hu
Location: New York, NY
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: September 29, 2017
Description:
The Maniatis lab iat CUMC is seeking a highly motivated Technician B to work on a project focusing on the role of innate immunity and autophagy pathways on the progression of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). The technician will work closely with colleagues using techniques such as gene expression profiling, in vitro cell culture assays, and in vivo mouse genetics.
Research Technologist, Morrison and Rothstein Labs
Employer: Johs Hopkins UniversityPrincipal Investigator: Fengua Hu
Location: Baltimore, MD
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: May 10, 2018
Description: A Research Technologist to work in the laboratories of Drs. Brett Morrison and Jeffrey Rothstein in the Department of Neurology. Our laboratories study the pathogenesis of the devastating motor neuron disease, amyotrophic lateral sclerosis (ALS; commonly referred to as Lou Gehrig’s disease). A particular focus is on the role played by oligodendrocytes, a key support cell in the brain that is dysfunctional and degenerates in ALS.
Science Officer
Employer: Prize4Life-IsraelPrincipal Investigator: Fengua Hu
Location: Tel Aviv, Israel
Sector: Non-Profit and Government
Degree Required: PhD, MD, MD/PhD
Conditions: ALS
Posted on: May 25, 2016
Description:
Prize4Life, a non-profit focused exclusively on accelerating the development of treatments for ALS, recipient of the 2011 Prime Minister Award for entrepreneurship and innovation, is looking for a Scientific Officer. We believe that biologists, chemists, engineers, clinicians, software developers and many others can all bring meaningful change to the field of ALS research, and victory over ALS can be, and should be, everyone’s.
Scientific Director, Research Professor
Employer: VIB and University of AntwerpPrincipal Investigator: Fengua Hu
Location: Antwerp, Belgium
Sector: Academia
Degree Required: PhD
Conditions: FTD, NDG
Posted on: January 2, 2018
Description:
VIB and UAntwerp are in search for a dynamic, internationally recognized leader in genetics and genomics to inspire and lead the VIB research centre at the University of Antwerp. The selected candidate will be appointed as scientific director at VIB and will have a research professor appointment (ZAPBOF) as (full) professor at the University of Antwerp.
Scientist
Employer: AlectorPrincipal Investigator: Fengua Hu
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: ALS, FTD
Posted on: July 10, 2017
Description:
As Scientist and critical member of the committed Neuro-Immunology team, you’ll help Alector discover and develop novel drugs targeting dementia and other neurological disorders. You will design and prioritize your own experiments and research endeavors to further Alector’s collective scientific understanding. In doing so you’ll apply your scientific insights to grow the company and guide its direction. Your work will be both inside and outside of the lab, and both strategic and hands-on. As an early hire, you’ll be influential in championing and developing Alector’s culture.
Scientist – Neuroscience FDE
Employer: Lilly NeurosciencePrincipal Investigator: Fengua Hu
Location: Indianapolis, IN
Sector: Industry
Degree Required: BSc, MSc
Conditions: NDG
Posted on: October 24, 2016
Description:
Lilly Neuroscience is seeking an associate-level scientist (Bachelors or Masters) to join the Neurodegeneration Team to facilitate its mission of discovering novel medicines for the treatment of Alzheimer’s disease, Parkinson’s disease, and other related neurodegenerative conditions. The individual must possess a keen interest to understand the pathophysiological processes that underlie neurodegenerative conditions such as Alzheimer disease and have an exceptional attention to scientific detail.
Scientist 1- CNS Discovery
Employer: Teva PharmaceuticalsPrincipal Investigator: Fengua Hu
Location: West Chester, PA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: June 6, 2016
Description:
The Discovery Research team has an opening for a neuropharmacologist at the Scientist 1 level. The qualified individual should have experience with the use and development of in vitro, ex vivo and in vivo approaches for CNS disorders including multiple sclerosis, neuroinflammation and neurodegeneration. Experience with iPSC models, primary cell screening concepts and/or drug repositioning will be an advantage.
Scientist I, ALS
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: August 12, 2017
Description:
Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention. The successful candidate will execute in vivo experiments to support the validation of novel drug targets and the development of small- and large-molecule drugs for the treatment of ALS. A major component of this work will be the assessment of drug candidates in a multiple rodent models, using a wide variety of morphological and functional endpoints, working closely with members of the ALS team as well as multiple internal and external collaborators. You will work in a fast paced, highly collaborative team environment at an exciting period for ALS research.
Scientist I, ALS
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: October 9, 2017
Description:
Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention. The successful candidate will execute in vivo experiments to support the validation of novel drug targets and the development of small- and large-molecule drugs for the treatment of ALS. A major component of this work will be the assessment of drug candidates in a multiple rodent models, using a wide variety of morphological and functional endpoints, working closely with members of the ALS team as well as multiple internal and external collaborators. You will work in a fast paced, highly collaborative team environment at an exciting period for ALS research.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: October 9th, 2017
Scientist I, Analytical Development (Small Molecule + ASO)
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: April 13, 2018
Description:
The individual will develop, implement, and qualify innovative analytical solutions for the characterization and testing of ASOs and pharmaceuticals (both off-line and on-line). This work will support process and formulation development and will drive the control strategy. Key areas of focus will be in enhanced impurity monitoring, simple and specific identity testing, and evaluating novel formulations. The primary methods are HPLC/UPLC, MS, and spectroscopy, but the use of other methods is required and should be explored.
Scientist I, Biomarkers
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: March 30, 2018
Description:
The Discovery and Early Development Biomarkers group, part of Biogen’s Research and Early Development department is seeking a highly motivated scientist to join a dynamic team engaged in the discovery and progression of novel biomarkers for neurodegenerative diseases.
Scientist I, Neuro Discovery, Research
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD, MD, PhD/MD
Conditions: NDG
Posted on: October 25, 2016
Description:
We seek an independent neuroscientist focused on identification of new targets for promoting axon regeneration, axon integrity and synapsis. The candidate will (1) be expected with the goal of delivering new targets to the clinic, focusing on multiple sclerosis and other neurodegenerative diseases, (2) apply in vitro and in vivo models to study the underlying mechanisms of degeneration and dysfunction in neurodegenerative diseases, (3) be familiar with cellular and animal models to study the effects of small molecules, antisense oligonucleotides, and antibodies for their roles in regeneration and repair, (4) enjoy membership amongst a highly productive and dynamic research team with many possibilities to collaborate internally and with external academic leaders, and (5) be expected to lead the project, present and publish their findings.
Scientist I, Research
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Conditions: NDG
Posted on: Aug 25, 2016
Description:
Perform Drosophila neurobiological research to study neuronal function including electrophysiology and imaging. Design and execute experiments that test disease biology and investigate neuronal function in genetic models of neurodegenerative disease in the fly. Conduct hands-on research and interact with other members of the Department of Neurology Research engaged in biomedical and behavioral studies. Perform research involving electrophysiological and imaging techniques in Drosophila.
Scientist I/II
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: November 29, 2017
Description:
Neurology Research at Biogen seeks a highly motivated and experienced associate scientist to join the new initiative on ALS (amyotrophic lateral sclerosis). The Neurology department is responsible for discovery research on pathogenic mechanisms of neurodegenerative disorders and translating these findings into novel strategies for therapeutic intervention.
Scientist I/II, NeuroImmunology
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: June 8, 2017
Description:
The Biogen Department of NeuroImmunology seeks a highly motivated and keen experimentalist whose primary responsibility is to advance drug discovery and development by performing bench research. The individual will be expected to design studies and execute research aimed at target discovery as well as the development of therapeutic approaches to treat acute neurological indications and chronic neurodegenerative diseases. The individual is expected to function independently and creatively within the context of project teams, drawing on pertinent literature, and to foster collaborations to maximize synergies and cross disciplinary approaches to advance the studies. The work will involve a wide array of in vitro and in vivo techniques and is expected to yield high quality publications.
Scientist I/II, Research
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD, MD, PhD/MD
Conditions: NDG
Posted on: October 25, 2016
Description:
The Biogen Epigenetics group seeks a highly motivated, creative scientist who will expand capabilities in epigenomic engineering within our Epigenetics and Cell & Gene Therapy groups, in consultation with colleagues in Neurology and Rare Disease groups. This scientist will have interests in the discovery and validation of mechanisms, pathways and potential drug targets for the treatment of neurodegenerative and rare diseases. S/he will create the means for the validation and modulation of targets of interest through the development of epigenomic engineering approaches for the modulation of disease-relevant target genes.
Scientist I/II, Research
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Conditions: NDG
Posted on: August 25, 2016
Description:
The Biogen Epigenetics group seeks a highly motivated, creative scientist who will expand capabilities in epigenomic engineering within our Epigenetics and Cell & Gene Therapy groups, in consultation with colleagues in Neurology and Rare Disease groups. This scientist will have interests in the discovery and validation of mechanisms, pathways and potential drug targets for the treatment of neurodegenerative and rare diseases. S/he will create the means for the validation and modulation of targets of interest through the development of epigenomic engineering approaches for the modulation of disease-relevant target genes.
Scientist I/II, Translational Sciences
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 9, 2017
Description:
The Biogen Department of Neuro/Immunology seeks a highly motivated and keen associate scientist whose primary responsibility is to advance target validation, drug discovery and development. The individual is expected to have mastered a broad range of experimental techniques, preferably having established expertise in the field of neuroimmunology. The individual will be expected to perform with significant independence with respect to designing and executing controlled experiments, analyzing and interpreting results, establishing and executing existing or new protocols/methodologies and recommending modifications. The individual is expected to read pertinent literature and exhibit knowledge of molecular and biological processes, applying their knowledge to propose new ideas and regularly make suggestions for creative solutions to technical challenges. The individual is expected to have strong written and verbal communication skills, preparing and delivering oral presentations, posters, draft research reports and contributing to manuscripts.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 9th, 2017
Scientist II, CRISPR/Cas Screening
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: February 19, 2018
Description:
Biogen is seeking an independent and highly motivated scientist to join the Chemical Biology group at the Scientist I/II level. Our group is responsible for identifying novel drug targets from phenotypic screens using cutting edge chemical biology and functional genomic techniques. The primary responsibilities for this position include the application of pooled CRISPR approaches to small molecule target identification in neurodegenerative diseases.
Scientist II, NeuroImmunology
Employer: BiogenPrincipal Investigator: Fengua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD, MD
Conditions: NDG
Posted on: Aug 17, 2016
Description:
The Neuroimmunology Research at Biogen is seeking a highly motivated scientist with a demonstrated track record of publications and presentations to drive independent basic exploratory research programs and lead cross-functional drug development team. The successful research scientist should possess a strong understanding of the mechanistic basis of neuroinflammation/neurodegeneration, as well as cutting edge knowledge on microglia and astrocyte biology, including familiarity with in vitro and in vivo models of neuroinflammation and neurodegenerative diseases. The scientist will be expected to apply a deep and broad knowledge of experimental neuroinflammation to creatively explore new biology and develop novel therapeutics. While prior drug development experience is preferred but not required, the candidate must have demonstrated the ability to work closely with research scientists in a team environment. Flawless oral and written communication skills are essential.
Scientist or Senior Scientist
Employer: Verge GenomicsPrincipal Investigator: Fengua Hu
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: September 7, 2017
Description:
Verge Genomics is seeking a Scientist or Senior Scientist to join the Neurobiology Research and Drug Discovery team. This candidate will bring significant academic and preferably pharmaceutical industry experience to conduct in vivo and in vitro research in our SF Bay Area laboratories and join team meetings at Verge Genomics headquarters in SF. The candidate will be responsible for the design and execution of target validation and evaluation of novel drug candidates for neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. The candidate will conduct in vivo studies in mice, including injections of gene modifying agents and drug candidates to neonatal and adult rodents using intracranial, oral, or intravenous administration routes. Experience with stereotaxic surgery, gene therapy (AAV9 or ASO), behavioral observations, gait analysis, rotarod and grip strength, and genotyping are a plus. The candidate will have extensive knowledge of CNS disease mechanisms, existing therapies, and experimental therapeutic approaches. The candidate will also culture motor neurons differentiated from induced pluripotent human stem cells and design and develop cellular assays to identify genes and compounds for treating neurodegenerative diseases including ALS and PD. The candidate will have extensive experience and leadership skills with sterile in vitro methods, including harvesting, storing, growing, and expanding neuronal cultures, formulating and adding compounds and molecular probes, measuring cells numbers and properties with immunohistochemical markers, and evaluating gene transfection. A keen ability to identify efficient solutions to laboratory problems and expertise with statistical analysis are essential. This position reports to the Director of Drug Discovery.
Employer: Verge Genomics
Location: San Francisco, CA
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: September 7th, 2017
Scientist or Senior Scientist, Discovery Biology
Employer: Prevail TherapeuticsPrincipal Investigator: Fengua Hu
Location: New York, NY
Sector: Industry
Degree Required: PhD or MD or MD/PhD
Conditions: NDG
Posted on: September 14, 2017
Description:
Prevail Therapeutics, Inc is a new biotech company based in New York City. Prevail is developing novel treatments for neurodegenerative disorders using gene and protein therapeutic modalities. Prevail is backed by a top-tier healthcare focused investment firm.
Scientist, In Vivo Biologist CNS Discovery Research, Manager
Employer: Teva PharmaceuticalsPrincipal Investigator: J. Paul Taylor
Location: New York, NY
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: May 1, 2016
Description:
Teva Pharmaceuticals has an opening for a Scientist 1 in vivo biologist. The individual should have substantial experience with the use and development of in vivo rat and/or mouse models for CNS disorders including neurodegeneration, including rodent behavior, surgical approaches, and genetic and/or viral vector modeling approaches. Knowledge of pharmacology and pharmacokinetics as they relate to CNS drug discovery is preferred.
Scientist, Medicinal Chemistry
Employer: Yumanity TherapeuticsPrincipal Investigator: J. Paul Taylor
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 9, 2018
Description:
This lab-based chemist will be a key part of an interdisciplinary team of scientists and will be involved in the design, synthesis, purification, and characterization of novel drugs in the areas of neurodegenerative disease. In this dynamic team focused role, the qualified candidate will also be expected to manage and run the chemistry laboratory, and act as a mentor for junior chemists as needed.
Employer: Yumanity Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 9th, 2018
Scientist, Neurological Rare Disease
Employer: SanofiPrincipal Investigator: Paul Taylor
Location: Framingham, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: May 24, 2017
Description:
Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly qualified and motivated Scientist to develop therapies for rare neurologic and neurodegenerative diseases. This laboratory based position will include the opportunity to lead project teams and interact with internal and external functions to initiate new drug discovery programs and advance ongoing projects. The candidate will use epigenetics tools, genome editing technologies, –omics, bioinformatics and other approaches to identify and validate new targets. The candidate will also advance understanding of the role of the non-coding genome to identify and validate innovative and transformative therapies for rare neurologic diseases.
Employer: Sanofi
Location: Framingham, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: May 24th, 2017
Scientist, Neuroscience
Employer: GenentechPrincipal Investigator: Paul Taylor
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: May 4, 2017
Description:
Genentech is inviting applications for a Scientist position (rank equivalent to assistant professor in academia) in the Department of Neuroscience. We are seeking an exceptional, highly motivated and creative scientist to lead innovative research efforts focused on unraveling the mechanisms of neurodevelopment and/or brain function in the context of nervous system diseases. He/she will also be expected to participate in inter-disciplinary teams to identify novel drug targets and discover new drugs to treat nervous system disorders. The ideal candidate will have significant experience in molecular and cellular biology using both in vitro and in vivo model systems, and possess a deep mechanistic understanding of the cellular pathways that contribute to diseases of the nervous system (e.g. neurodegenerative diseases). A solid track record of publications in top tier journals is required as is exceptional communication skills. The position will involve close collaboration with other research labs in Neuroscience as well as investigators in areas such as human genetics, bioinformatics, proteomics, imaging, and small molecule and large molecule drug discovery. The successful candidate will be expected to publish their research in high quality journals.
Scientist, Protein Sciences
Employer: Denali TherapeuticsPrincipal Investigator: Paul Taylor
Location: San Francisco, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: September 15, 2017
Description:
Denali Therapeutics is seeking a Scientist with expertise in antibody and protein expression and purification to contribute to our drug discovery efforts.
Senior Associate Scientist
Employer: Yumanity TherapeuticsPrincipal Investigator: Paul Taylor
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 30, 2017
Description:
Position Overview:
Senior Associate Scientist
Employer: AmgenPrincipal Investigator: Paul Taylor
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: March 28, 2017
Description:
We are seeking a Research Senior Associate Scientist to join a vibrant and growing group currently focusing on Neurodegenerative diseases within the Neuroscience Therapeutic Area, a key component of the Discovery Research unit at Amgen’s site in Cambridge, MA (Amgen MAssachusetts-AMA). The successful candidate must be highly motivated with a deep interest in developing new and effective therapeutics for Parkinson’s disease (PD)/ALS.
Senior Associate Scientist, ALS and PD
Employer: AmgenPrincipal Investigator: Paul Taylor
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: June 20, 2017
Description:
We are seeking a Research Senior Associate Scientist to join a vibrant and growing group currently focusing on Neurodegenerative diseases within the Neuroscience Therapeutic Area, a key component of the Discovery Research unit at Amgen’s site in Cambridge, MA (Amgen MAssachusetts-AMA). The successful candidate must be highly motivated with a deep interest in developing new and effective therapeutics for Parkinson’s disease (PD)/ALS.
Senior Associate Scientist, Neuroimmunology
Employer: BiogenPrincipal Investigator: Paul Taylor
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: March 15, 2017
Description:
The Neuroimmunology department at Biogen is searching for a committed, enthusiastic and dependable associate scientist to assist with the design, execution and interpretation of preclinical studies for drug discovery and development. The incumbent will be part of a multifunctional team with responsibility for target validation and evaluation of novel drug candidates for neurodegenerative/neuroinflammatory diseases. He/she should be able to plan and execute in vivo and in vitro experiments with high level of independency, organization and scientific rigor. He/she should be able to maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 15th, 2017
Senior Clinical Trial Manager
Employer: CytokineticsPrincipal Investigator: Paul Taylor
Location: South San Francisco
Sector: Industry
Degree Required: BS
Conditions: NDG
Posted on: April 1, 2016
Description:
We are currently seeking a Senior Clinical Trials Manager to join our Clinical Operations group to provide key clinical support for the management, operation, and execution of multiple clinical trials (including global international trials) for Cytokinetics clinical programs.
Employer: Cytokinetics
Location: South San Francisco
Sector: Industry
Degree required: BS
Conditions: NDG
Job posted: April 1st, 2016
Senior Manager/Associate Director Pharmacometrician
Employer: Teva PharmaceuticalsPrincipal Investigator: Paul Taylor
Location: Frazer, PA
Sector: Industry
Conditions: NDG
Posted on: Sep 11, 2016
Description:
The Pharmacometrician is responsible for the construction, validation, and implementation of disease, placebo, exposure-response, and mechanistic PKPD models to evaluate risk/benefit and facilitate drug development decisions, in close collaboration with Clinical Pharmacologists and other R and D partners.
Senior Manager/Associate Director, Informatics
Employer: CytokineticsPrincipal Investigator: Paul Taylor
Location: South San Francisco, CA
Sector: Industry
Degree Required: BS, MS, PhD
Conditions: NDG
Posted on: April 1, 2016
Description:
Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators as potential treatments for debilitating diseases in which muscle performance is compromised and/or deteriorating. With an unmatched understanding of muscle biology and mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to increase muscle function and contractility. Working collaboratively, Cytokinetics’ dedicated employees are focused on advancing novel mechanism therapeutics to dramatically improve the lives of patients. With purpose and passion, we have committed to make an important impact on serious medical illnesses.
Senior Research Associate, Neurobiology
Employer: Verge GenomicsPrincipal Investigator: Paul Taylor
Location: San Francisco, CA
Sector: Industry
Degree Required: BS or MS
Conditions: ALS
Posted on: April 15, 2018
Description:
Verge Genomics is seeking a Research Associate or Sr. Research Associate to join the Neurobiology Research and Drug Discovery team and contribute to innovative research in finding therapies to treat CNS diseases. This candidate will bring pharmaceutical industry experience to conduct in vivo and in vitro research in our SF Bay Area laboratories and join team meetings at Verge Genomics headquarters in SF. The qualified candidate will be highly motivated, interactive and creative with ability to work across functions and projects. The candidate is responsible for contributing to the execution of target validation and evaluation of novel drug candidates for neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. The ideal candidate will have working knowledge of CNS disease and or mechanisms with existing and experimental therapeutic approaches. A keen ability to identify efficient solutions to laboratory problems and working knowledge with statistical analysis are essential. This position reports to the Director of Drug Discovery.
Employer: Verge Genomics
Location: San Francisco, CA
Sector: Industry
Degree required: BS or MS
Conditions: ALS
Job posted: April 15th, 2018
Senior Research Associate, Neuroscience
Employer: Voyager TherapeuticsPrincipal Investigator: Udai Pandey
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: April 5, 2018
Description:
Voyager is seeking a highly motivated biologist to contribute to our research team at our facility in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in in vitro and in vivoexperimental methods, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. The individual will work in the laboratory and be responsible for experimental execution, and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. We are looking for extensive prior hands-on in with techniques such as cell culture, in vitro assay development and execution, CNS tissue preparation, qRT-PCR, western, and ELISA.
Senior Research Investigator
Employer: University of PennsylvaniaPrincipal Investigator: Udai Pandey
Location: Philadelphia, PA
Sector: Academia
Degree Required: PhD
Conditions: ALS
Posted on: March 19, 2018
Description:
The Gene Therapy Program (GTP) and Orphan Disease Center (ODC) are entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases. Our R&D organization has a translational infrastructure that includes: technology discovery, specialized immunology assays operating under GLP, a Vector Core/Manufacturing unit that conducts GMP comparable work, and a large non-clinical program for animal testing under GLP including large NHP and rodent vivaria.
Senior Research Project Manager
Employer: Columbia UniversityPrincipal Investigator: Beau Ances
Location: New York, NY
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: November 9, 2017
Description:
The IGM is seeking a Senior Research Project Manager interested in joining a group of Investigators using cutting edge genomic technology to study genetics with a primary focus on identifying and biologically characterizing genetic variation underlying human disease.
Senior Scientist
Employer: AveXisPrincipal Investigator: Beau Ances
Location: San Diego, CA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: January 16, 2018
Description:
AveXis is seeking an experienced Sr. Lab Scientist to join the dynamic and growing analytical team to help establish analytical methods for process characterization and lot release of the clinical or commercial materials. The individual will collaborate closely with the internal R&D team to develop and optimize meaningful, next-generation cell-based potency and other functional assays in support of development and commercialization of new gene therapy medicines. The individual will be responsible for assay optimization and troubleshooting as well as for ensuring consistency of assay performance and cell culture work. The individual will play an important role in method qualification/validation and method transfer to internal and/or external QC laboratories. Responsibilities will also include execution of routine assays and supporting lab operation. Successful candidate will have extensive experiences in tissue culture work and will be a fast-learner with passion for innovative technology and science.
Employer: AveXis
Location: San Diego, CA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: January 16th, 2018
Senior Scientist
Employer: EvotecPrincipal Investigator: Steven Finkbeiner
Location: Hamburg, Germany
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: November 24, 2017
Description:
Evotec’s headquarters in Hamburg (Germany) is seeking a highly motivated and creative Senior Scientist (f/m) Biomarker in Neurodegeneration Research full-time and permanent to join our Neurobiology Department and help drive projects in the research area of Huntington’s Disease and other neurodegenerative disorders.
Senior Scientist
Employer: Sage BionetworksPrincipal Investigator: Steven Finkbeiner
Location: Seattle, WA
Sector: Nonprofit
Degree Required: PhD
Conditions: NDG
Posted on: May 7, 2018
Description:
Sage Bionetworks is recruiting a scientist with bioinformatics or computational biology experience to lead integrative genomic analysis within multiple consortia of biologists and computational biologists studying neurodegenerative and neuropsychiatric diseases.
Senior Scientist
Employer: Voyager TherapeuticsPrincipal Investigator: Fenghua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: April 24, 2018
Description:
Voyager Therapeutics is developing recombinant adeno-associated virus (rAAV) vectors for treating neurological diseases. Developing robust and reliable vector production processes is central for establishing successful gene therapy applications. Voyager is seeking a highly motivated Senior Scientist and/or Engineer to join the Process Development Group with a focus on upstream production. The qualified candidate will be a leader within the group with a strong background and expertise in cell culture manufacturing of biologics. Primary responsibilities will include carrying out upstream process development activities for the manufacture of pre-clinical and cGMP grade rAAV products, participating in and leading internal productions, writing appropriate documents and carrying out technology transfer to assorted CMOs, and finally participating in cGMP manufacture person in plant activities. The ability to independently organize and design experiments, analyze data and report the results of their and other’s work in a concise and well documented manner, and to take the initiative to successfully drive Voyager’s projects and manufacturing process are all important aspects of the position.
Senior Scientist
Employer: Yumanity TherapeuticsPrincipal Investigator: Fenghua Hu
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: November 28, 2017
Description:
Yumanity is seeking a creative, talented and versatile Ph.D scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based, and requires strong experimental skills in neurobiology and assay development. The scientist in this position will collaborate across all Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry.
Senior Scientist, ALS
Employer: SanofiPrincipal Investigator: Fenghua Hu
Location: Framingham, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: March 9, 2018
Description:
Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly motivated Sr. Scientist to help identify innovative therapies for amyotrophic lateral sclerosis (ALS). The successful candidate will implement manifold in vitro experimental approaches to investigate the underlying disease biology of ALS and to validate novel therapeutic targets for the treatment of ALS. These techniques include cell culture, molecular biology, biochemistry, immunoblotting, immunohistochemistry, and microscopy. The successful candidate will also use transgenic mouse models to support the in vivo investigation of potential therapeutic approaches.
Employer: Sanofi
Location: Framingham, MA
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: March 9th, 2018
Senior Scientist, Analytical Development
Employer: Voyager TherapeuticsPrincipal Investigator: Knoxville
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD or MS
Conditions: ALS
Posted on: April 27, 2018
Description:
Voyager is seeking a highly motivated scientist to contribute to the Analytical Development group. The qualified candidate will participate in development, qualification, and transfer of new state-of-the-art analytical methods to be used for characterization and release of Voyager’s products. This role is currently an individual contributor but may expand to having direct reports in the future. This position is located in Cambridge, MA. Primary responsibilities include, but are not limited to, the following:
Senior Scientist, Neuroinflammation
Employer: MerckPrincipal Investigator: Knoxville
Location: Boston, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: March 24, 2017
Description:
The Merck Early Discovery Neuroscience team is seeking a highly motivated and technically skilled neuroscientist with a strong background in neuroimmunology to join our Boston-based early drug discovery team. Position is for a lab-based biologist who will generally be responsible for supporting the identification and validation of novel targets. The primary responsibilies will include the design and execution of both in vitro experiments and in vivo studies – applying biochemical, cellular/molecular, histological and imaging techniques – to drive toward a deeper understanding of disease pathogenesis, establish novel models thereof, and enable mechanism of action assessments for candidate therapeutics. The Senior Scientist will be an active participant in the critical scientific dialogue that supports our mission of early discovery in support of the Merck Neuroscience pipeline.
Senior Scientist, Neuroscience
Employer: MerckPrincipal Investigator: Knoxville
Location: West Point, PA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: September 21, 2017
Description:
As a Senior Scientist in Merck’s Neuroscience Department you will engage in exciting drug discovery research targeting the treatment of Neurodegenerative diseases. An expert in cellular and molecular biology, you will have the opportunity to work as part of a high profile team applying cutting edge cell biology techniques to identify, validate and progress innovative novel drug targets. You will design, implement and run biochemical and cell based assays to support our drug discovery efforts.
Senior Scientist, Neuroscience
Employer: MerckPrincipal Investigator: Knoxville
Location: Boston, MA
Sector: Industry
Degree Required: PhD
Conditions: NDG
Posted on: April 19, 2018
Description:
The Merck Early Discovery Neuroscience team is seeking a passionate, research focused and technically skilled in-vitro scientist with strong molecular, cellular and biochemistry expertise in neurodegenerative diseases to join our Boston-based research community. The high-level goal of the group is to effectively advance de novo discoveries from within the laboratory toward medicines to treat neurodegenerative diseases. The concentration of the group is centered on understanding the key determinants of microglia that impact their functional responses to neurodegenerative disease states. Mainly, how do genetic mutations in selected neuroimmune genes confer neurodegenerative susceptibility and by what common or unique mechanisms? By generating and characterizing transgenic models and developing cell-based systems, the team aims to gain insights into causal disease pathophysiology informed by human genetics using combinations of molecular and functional profiling technologies. Target, pathway and functional insights are pressure-tested with pharmacological, biologic and genetic experimental tools to validate insights and mechanistic hypotheses. A core part of the group mission and responsibility of the Senior Scientist is to establish, optimize and transfer insights and assays to enable target and pathway screening. To that goal, candidates with extensive expertise in cellular and molecular neuroscience with de novo assay development experience are encouraged to apply.
Employer: Merck
Location: Boston, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: April 19th, 2018
Senior Scientist, Neuroscience Research & Drug Discovery
Employer: Verge GenomicsPrincipal Investigator: Knoxville
Location: San Francisco, CA
Sector: Industry
Degree Required: MSc, PhD
Conditions: ALS, NDG
Posted on: Aug 16, 2016
Description:
Verge Genomics is seeking a highly motivated individual to spearhead pre-clinical development of disease modifying treatments for neurodegenerative diseases. You will be responsible for advancing our current and emerging lead candidate pipeline through all stages of pre-clinical development, acting as a leader of multidisciplinary project teams. You will oversee important external collaborations with contract research organizations (CROs), leading academic groups, non-profits, and pharmaceutical partners. As one of the first employees at Verge, you will develop help build the foundation of a revolutionary drug development model.
Senior Scientist, Process Development
Employer: Voyager TherapeuticsPrincipal Investigator: Knoxville
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD
Conditions: ALS
Posted on: February 1, 2018
Description:
Voyager is seeking two highly motivated Senior Scientists to join the Process Development Group with a focus on (1) upstream; and (2) downstream purification.
Senior Technician, Project ALS Preclinical Core Facility
Employer: Columbia UniversityPrincipal Investigator: Knoxville
Location: New York, NY
Sector: Academia
Degree Required: BS
Conditions: ALS
Posted on: February 3, 2018
Description:
An exciting opportunity for a motivated Senior Technician to join our new Project ALS Preclinical Core Facility at Columbia University Medical Center. The facility tests new treatment strategies and research drugs in mouse models of amyotrophic lateral sclerosis.
Senior Technician, Project ALS Preclinical Core Facility
Employer: Columbia UniversityPrincipal Investigator: Knoxville
Location: New York, NY
Sector: Academia
Degree Required: BA or BS
Conditions: ALS
Posted on: November 9, 2017
Description:
An exciting opportunity for a motivated Senior Technician to join our new Project ALS Preclinical Core Facility at Columbia University Medical Center. The facility tests new treatment strategies and research drugs in mouse models of amyotrophic lateral sclerosis.
Sr. Associate Scientist, Neurobiology
Employer: BiogenPrincipal Investigator: Knoxville
Location: Cambridge, MA
Sector: Industry
Degree Required: BA or BS
Conditions: NDG
Posted on: October 24, 2017
Description:
The Neurodegeneration and Repair Research Unit is seeking a motivated and experienced scientist to join a group a cutting edge research group focused on the rapid progression of novel therapeutics for neurodegeneration. The successful candidate will join a highly productive team that has established robust in vivo and in vitro assays, in support of project and company drug discovery and development goals.
Sr. Clinical Scientist
Employer: BiogenPrincipal Investigator: Miguel Esteves
Location: Cambridge, MA
Sector: Industry
Degree Required: PhD or PharmD
Conditions: NDG
Posted on: October 26, 2017
Description:
The Sr. Clinical Scientist will work with the Medical Director functions of Early Clinical Development teams and provide scientific and clinical input into early stage clinical development programs. This role will work on cross-functional study teams for the design, execution, and monitoring of clinical trials, early clinical research studies, and/or external research projects, as well as assist with data interpretation and communication.. This individual will report directly into a Sr. Medical Director of Clinical Development or a Therapeutic Area VP and will interface directly with other functions including Clinical Development, Clinical Pharmacology, and Biomarkers.
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD or PharmD
Conditions: NDG
Job posted: October 26th, 2017
Sr. Research Associate/Scientist I, Discovery Biology
Employer: CytokineticsPrincipal Investigator: Miguel Esteves
Location: South San Francisco, CA
Sector: Industry
Degree Required: BS, MS, PhD
Conditions: NDG
Posted on: May 13, 2016
Description:
Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators as potential treatments for debilitating diseases in which muscle performance is compromised and/or deteriorating. We seek a highly motivated and experienced Senior Research Associate/ Scientist I to join our Discovery Biology group. This individual will play a key role in designing, optimizing, and implementing a wide-range of biochemical and cell-based assays, as well as in assessing biochemical and cellular activity of candidate compounds. As a member of a multidisciplinary team, you will work closely with team members to identify, characterize and advance compounds through research and preclinical development.
Staff Associate, Pellizzoni Lab
Employer: Columbia UniversityPrincipal Investigator: Miguel Esteves
Location: New York, NY
Sector: Academia
Degree Required: BA or BS
Conditions: ALS, SMA
Posted on: November 1, 2017
Description:
Columbia University’s Department of Pathology and Cell Biology has an immediate opening for a Staff Associate/Sr. Staff Associate position in Dr. Livio Pellizzoni’s lab.The incumbent will be responsible for carrying out fully planned experiments, in liaison with Postdoctoral Research Scientists/Fellows as well as PhD students, to study the molecular and cellular mechanisms of neurodegenerative disease in mouse models. The incumbent will use conventional biochemical, cellular, molecular, immuonohistochemical and behavioral assays. He/She will also maintain the mouse colonies, daily behavioral monitoring of mice, genotyping, ICV/IP injections, tissue dissection and immunohistochemistry. The incumbent will also be responsible for confocal microscopy, image analysis, statistical evaluation of results, as well as preparing solutions and performing other laboratory related duties necessary to the functioning of the research projects.
Employer: Columbia University
Location: New York, NY
Sector: Academia
Degree required: BA or BS
Conditions: ALS, SMA
Job posted: November 1st, 2017
Staff Scientist, Medicinal Chemistry
Employer: Yumanity TherapeuticsPrincipal Investigator: Miguel Esteves
Location: Cambridge, MA
Sector: Industry
Degree Required: BS or MS
Conditions: NDG
Posted on: April 20, 2018
Description:
This lab-based chemist will be a key part of an interdisciplinary team of scientists and will be involved in the design, synthesis, purification, and characterization of novel drugs in the areas of neurodegenerative disease. In this dynamic team focused role, the qualified candidate will also be expected to manage and run the chemistry laboratory, and act as a mentor for junior chemists as needed.
Statistical Programmer
Employer: University of MiamiPrincipal Investigator: Shuying Sun
Location: Miami, FL
Sector: Academia
Degree Required: BSc, MSc
Conditions: ALS
Posted on: October 25, 2016
Description:
The Neuromuscular Program in the Department of Neurology at the University of Miami has an exciting opportunity for a full-time or part-time Statistical Programmer to join an active clinical and translational research group focused on therapy development for Lou Gehrig’s disease (Amyotrophic Lateral Sclerosis, or ALS). The statistical programmer will be an integral member of the research team and provide programming support for the cleaning, summarizing/reporting, and analysis of research data. The statistical programmer will work most closely with the biostatistician and the data manager. The appropriate title for the position will be contingent upon the selected candidate’s education and years of experience. Candidates with additional experience could be considered for a Sr. Statistical Programmer position.
Statistical Programmer, Neuromuscular Program
Employer: University of MiamiPrincipal Investigator: Shuying Sun
Location: Miami, FL
Sector: Academia
Degree Required: BS or MS
Conditions: ALS
Posted on: January 03, 2017
Description:
The Neuromuscular Program in the Department of Neurology at the University of Miami has an exciting opportunity for a full-time or part-time Statistical Programmer to join an active clinical and translational research group focused on therapy development for Lou Gehrig’s disease (Amyotrophic Lateral Sclerosis, or ALS). The statistical programmer will be an integral member of the research team and provide programming support for the cleaning, summarizing/reporting, and analysis of research data. The statistical programmer will work most closely with the biostatistician and the data manager. The appropriate title for the position will be contingent upon the selected candidate’s education and years of experience. Candidates with additional experience could be considered for a Sr. Statistical Programmer position. The primary responsibilities are: Develop and implement strategies for real-time data QC. Conduct routine data checks to ensure data integrity. Write SAS macros and programs for data cleaning, reporting (e.g. tables, listings, figures), and the creation of analysis datasets. Construct view tables from a MySQL database. Perform statistical analyses defined in statistical analysis plans, as needed. Perform other related duties and responsibilities, as assigned.
Employer: University of Miami
Location: Miami, FL
Sector: Academia
Degree required: BS or MS
Conditions: ALS
Job posted: January 3rd, 2017
Technician B – Tom Maniatis Laboratory
Employer: Columbia UniversityPrincipal Investigator: Shuying Sun
Location: New York, NY
Sector: Academia
Degree Required: BSc
Conditions: ALS
Posted on: October 25, 2016
Description:
The Maniatis lab is seeking a highly motivated Technician B to work on a project focusing on the progression of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). The technician will work closely with colleagues using techniques such as in vivo mouse genetics, gene expression profiling and in vitro cell culture assays. Comfortability with dissections preferred.
Translational Scientist
Employer: Tsinghua University School of MedicinePrincipal Investigator: Shuying Sun
Location: Beijing, China
Sector: Academia
Degree Required: MD and/or PhD
Conditions: NDG
Posted on: July 14, 2017
Description:
We sincerely invite applications from outstanding translational scientists who aim to conduct cutting-edge and innovative research. Successful applicants will be offered generous start-up packages and internationally competitive benefits. Positions will remain open until filled.
Assistant Professor, Neuropsychology
Employer: University of Pennsylvania School of MedicinePrincipal Investigator: Shuying Sun
Location: Philadelphia, PA
Sector: Academia
Degree Required: PhD
Conditions: ALS, FTD
Posted on: January 05, 2017
Closes: January 05, 2019
Description:
The Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Assistant Professor position in the non-tenure clinician-educator track. The successful applicant will have experience in the field of Neurology with a focus on Neuropsychology. Applicants must have a Ph.D. degree and have demonstrated excellent qualifications in clinical care and research. The successful applicant must have completed a two-year post-doctoral fellowship in clinical neuropsychology, and be board eligible or licensed to practice Neuropsychology.
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