Figure 1. Micrographs of spinal cord motoneurons showing SOD1-immunoreactive inclusions.
Image credit: Forsberg, et. al. 2010 under CC BY license

Job Opportunities

To submit any new job opportunities for this list, please email ALSjobs@prize4life.org. List the employer, location, closing date if applicable, and a link to more information. Jobs are removed after 3 months, unless requested otherwise.

This free job bulletin board aims to help scientists identify job opportunities in the field of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Positions described as broadly spanning neurodegenerative diseases (NDG) are noted as ‘NDG‘. The job listing includes research positions at all levels, as well as non-research positions for which a research background at the MS, PhD, or MD level is required.


Click the title of any table column to sort.

Academia

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
NEW! Research Assistant

Research Assistant

(Click title to open job details in a new window.)
Description:

We are seeking a research assistant to produce proteins related to the ALS (Motor Neuron disease), as part of an international project to generate high-quality antibodies for therapeutic research.


You will have a degree in biology/biochemistry and proven experience in cloning, expressing and purifying proteins from bacterial and eukaryotic cells. You will be required to adapt or develop procedures for expressing and purifying the target proteins to a high standard of yield and purity.


You will be able to work as part of a multidisciplinary team and be well-organised in planning and documenting experiments.


The post is full-time and available on a fixed-term contract until 31 December 2020 in the first instance.


You will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.


Only applications received before 12.00 noon on 14 May 2018 will be considered.


Link: http://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=134505
Employer: University of Oxford
Location: Oxford, England
Sector: Academia
Degree required:
Conditions: ALS
Job posted: April 17th, 2018
Applications close: May 14th, 2018
University of OxfordOxford, EnglandALSApr 17, 2018
NEW! Research Assistant

Research Assistant

(Click title to open job details in a new window.)
Description:

Applications are invited for the post of Research Assistant working on an exciting project which aims to improve the way in which the NHS delivers respiratory therapies, such as non-invasive ventilation (NIV), to patients with motor neurone disease (MND). You will work on Work Packages 2, 3 and 4 of this project. Work Package two involves carrying out a survey to explore current clinical practices and standards relating to the use of NIV in MND in the UK and in similar services to the NHS within Europe. Work Package 3 involves carrying out stakeholder consultations to explore and contextualise the research findings from previous Work Packages and to gain input about how best to translate them into clinical practice. Work Package 4 focuses on creating and testing a practical information toolkit to support the practice of healthcare professionals involved in the respiratory management of MND patients.


You will work to closely with clinicians and researchers at University of Sheffield’s Department of Neuroscience Sheffield Institute for Translational Neurosciences, the School of Health and Related Research, the Psychology department and IT specialists. SITraN is in an internationally recognised multidisciplinary group of scientists and clinicians with expertise in translating research into clinical practice in neurological diseases and is a core member of the prestigious NIHR Sheffield Biomedical Research Centre.


The salary is Grade 6, £25,728 – £29,799 per annum. Potential to progress to £32,548 per annum. To apply for this position, click here.


Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVEODhGQUQzQTVERjE0NTlEOEUmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos#
Employer: University of Sheffield
Location: Sheffield, England
Sector: Academia
Degree required:
Conditions: ALS
Job posted: April 13th, 2018
Applications close: April 25th, 2018
University of SheffieldSheffield, EnglandALSApr 13, 2018
NEW! Postdoctoral Fellow, Sun Lab

Postdoctoral Fellow, Sun Lab

(Click title to open job details in a new window.)
Description:

Postdoctoral opportunities are available in Dr. Shuying Sun’s laboratory at Johns Hopkins University School of Medicine. The lab will explore the fascinating frontiers of RNA metabolism dysfunction and RNA-targeting therapy in neurodegenerative diseases by combining molecular and cellular approaches, genome editing, proteomic, genomic and screening platforms.


The nervous system has extremely complex RNA processing regulation and dysfunction of RNA metabolism has emerged to play crucial roles in multiple neurological diseases. Mutations and pathologies of several RNA-binding proteins are found to be associated with neurodegeneration in both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). An alternative RNA-mediated toxicity arises from microsatellite repeat instability in the human genome. The expanded repeat-containing RNAs could potentially induce neuron toxicity by disrupting protein and RNA homeostasis through various mechanisms.


The Sun lab is interested in deciphering the molecular mechanisms of disease pathogenesis and seeks to translate the mechanistic findings to therapeutic target development to advance treatment options against neurodegenerative diseases. We are looking for highly motivated postdoc fellows with solid PhD training in biochemistry, molecular and cellular biology. Experiences with RNA biology, neuroscience or bioinformatics are preferred but not limited to. You will join a strong and highly interactive science community at Johns Hopkins.


Interested candidates should provide a cover letter (with statement of research interest and career goals), CV and the contact information for three references to Dr. Shuying Sun at shuying.sun@jhmi.edu. Please visit our lab website at http://labs.pathology.jhu.edu/sun/ for additional information.


Link: https://www.nature.com/naturejobs/science/jobs/641473-postdoctoral-positions-on-rna-biology-and-neurodegenerative-disease
Employer: Johns Hopkins University School of Medicine
Location: Baltimore, MD
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: April 10th, 2018
Johns Hopkins University School of MedicineBaltimore, MDPhDALS, FTDApr 10, 2018
Assistant Professor of Neurology

Assistant Professor of Neurology

(Click title to open job details in a new window.)
Description:

The Center of Image Acquisition (CIA) at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute seeks a qualified applicant for an Assistant Professor (tenure track) position in the USC Department of Neurology. The CIA serves as central resource for the development and application of advanced imaging for all neuroimaging research at the Keck School of Medicine of USC. The CIA will interact and collaborate with many departments at the Health Sciences Campus and the University Park Campus conducting research in methodology and its application in the study of normal, neurological and psychiatric cohorts. The ideal candidate should have a Ph.D. in Biophysics, Biomedical Engineering, or a related field, and have 2-3 years of postdoctoral training in the field of MRI physics and its applications in neuroscience. The candidate is expected to develop innovative MRI techniques, in particular noninvasive blood flow and perfusion imaging. The main duties of this position include the development of an independent and/or collaborative research program and participation in multidisciplinary research applying novel MRI imaging techniques for assessing and diagnosing neurovascular and neurodegenerative diseases. Experience on pulse sequence programming, particularly on Siemens platform is highly desirable.


Link: https://jobs.sciencecareers.org/job/477691/assistant-professor-of-neurology-tenure-track-/
Employer: University of Southern California
Location: Los Angeles, CA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: April 5th, 2018
University of Southern CaliforniaLos Angeles, CAPhDNDGApr 05, 2018
Assistant Professor, Neurology

Assistant Professor, Neurology

(Click title to open job details in a new window.)
Description:

The USC Stevens Neuroimaging and Informatics Institute (INI) seeks highly-qualified applicants for the position of Assistant Professor (tenure-track). The successful applicant will have a minimum 5+ years experience (post doctoral degree) in imaging in aging and neurodegenerative diseases. A particular emphasis on functional and structural connectivity in Alzheimer’s disease is desired. The candidate should have specific interest in mechanistic processes of aging include neuroinflammation, and/or genetics. A strong foundation in understanding the role of imaging, genetics, and clinical phenotypes in characterizing age- and disease-related phenomena is desired. The candidate should have a PhD in Neuroscience, Psychology, or other related disciplines; a strong foundation in neuroimaging and 5+ years post-PhD research experience with a successful publication record and teaching experience is required. The applicant must demonstrate an ability to work with a highly collaborative and multidisciplinary team. Further, the applicant must have demonstrated a strong track record of obtaining independent funding to support a research program.


To apply, include a cover letter, CV, salary history and list of references. Include in your cover letter where you saw this posting or how you learned of this opening.


Link: https://jobs.sciencecareers.org/job/477692/assistant-professor-of-neurology-tenure-track-/
Employer: University of Southern California
Location: Los Angeles, CA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: April 5th, 2018
University of Southern CaliforniaLos Angeles, CAPhDNDGApr 05, 2018
Postdoctoral Fellow, Deleidi Lab

Postdoctoral Fellow, Deleidi Lab

(Click title to open job details in a new window.)
Description:

A position for a talented and highly motivated Postdoctoral Researcher is available within the scientific team “Mitochondria and Inflammation in Neurodegeneration” led by Michela Deleidi in Tübingen. The research focus of our group is on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in neurodegenerative diseases. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson’s disease. Our aim is to understand, at the molecular level, how immune responses within or outside the brain contribute to neurodegeneration. Our final goal is to translate fundamental discoveries to better preventive and therapeutic approaches for neurodegenerative diseases. Please see our website for more information about our research: https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/deleidi/research-areasfocus/.


The successful candidate will conduct a research project aimed at further elucidating the link between metabolic and energetic defects and immune homeostasis in Parkinson’s disease. The project will involve close collaborations with international partners. For this project, a combination of in-vitro models (human cell lines including induced pluripotent stem cells) and in-vivo models (mouse models) will be used as well as a variety of approaches including use of human induced pluripotent stem cells (2D, 3D and brain organoids), CRISPR-Cas9 genome editing, flow cytometry, microscopy, RNA-seq and metabolomics, and use of in-vivo models (with external collaborators). You will conduct your own research project, collaborating with PhD and Postdoctoral Researchers as well as international partners. The goal is to publish our work in outstanding scientific journals.


Link: https://www.nature.com/naturejobs/science/jobs/641215-postdoctoral-researcher-f-m
Employer: German Center for Neurodegenerative Diseases
Location: Tübingen, Germany
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: April 5th, 2018
German Center for Neurodegenerative DiseasesTübingen, GermanyPhDNDGApr 05, 2018
Postdoctoral Fellow, Dupuis Lab

Postdoctoral Fellow, Dupuis Lab

(Click title to open job details in a new window.)
Description:

A 3-year post-doctoral position is available in Inserm U1118, Strasbourg, France under the supervision of Dr Luc DUPUIS.


The successful candidate will investigate the relationships between TAU, FUS and TDP-43 in the development of amyotrophic lateral sclerosis and fronto-temporal dementia, two related neurodegenerative diseases currently untractable. This will be done by combining mouse genetics and behaviour with molecular biology techniques based on next generation sequencing and pathological studies in patient tissues.


An experience in NGS techniques such as RNAseq and/or CLIPseq will be highly appreciated.


The position is secured for 3 years, and funded by the ANR.


Applications including a detailed CV and contact of at leat two previous supervisors, should be sent to Dr Luc Dupuis (ldupuis@unistra.fr).


Recent publications from the laboratory:


Vercruysse P, et al. Brain. 2016, Apr;139(Pt 4):1106-22.

El Oussini H, et al. Acta Neuropathol. 2016, 131(3):465-80

Scekic-Zahirovic J.,et al. EMBO J., 2016, 35(10):1077-97. doi: 10.15252/embj.201592559.

Dentel C, et al. . Brain. 2013 Feb;136(Pt 2):483-93.

Kabashi E, et al. Hum Mol Genet. 2013 Jun 15;22(12):2350-60.

Dupuis L, et al. Lancet Neurol. 2011 Jan;10(1):75-82.


Employer: Inserm U1118
Location: Strasbourg, France
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: April 4th, 2018
Inserm U1118Strasbourg, FrancePhDALS, FTDApr 04, 2018
Research Associate, McDermott Lab

Research Associate, McDermott Lab

(Click title to open job details in a new window.)
Description:

We are seeking an outstanding early-career researcher with the potential to become a leader in the field of mixed-methods health services research. You will join the research group of Professor Christopher McDermott at the Sheffield Institute for Translational Neuroscience (SITraN) to work on clinical research projects focusing on the supportive and symptomatic management of patients with motor neurone disease (MND) and other neurodegenerative disorders.


This post provides an excellent opportunity to undertake high quality research within a stimulating multi-disciplinary context. You will work directly with a team of clinicians and researchers on HighCALS, a National Institute for Health (NIHR) funded research programme, with the aim to develop and evaluate a complex intervention to achieve a high calorie diet for people with Amyotrophic Lateral Sclerosis (ALS). HighCALS is a collaboration of co-investigators from the Sheffield Institute for Translational Neuroscience (SITraN), the School of Health and Related Research (ScHARR) and the Department of Psychology at the University of Sheffield; and the School of Food Science and Nutrition at the University of Leeds.


You will have a Masters or PhD in a relevant discipline or equivalent experience.


This post is full time, fixed term for 2 years. The salary is Grade 7,

£30,688 – £38,883 per annum.  Potential to progress to £42,418 per annum.


Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVFODhDQ0QzOTQ3RTQ3MzE3NEYmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos#
Employer: University of Sheffield
Location: Sheffield, England
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: April 4th, 2018
Applications close: May 2nd, 2018
University of SheffieldSheffield, EnglandPhDALSApr 04, 2018
Chair, Department of Translational Neurosciences

Chair, Department of Translational Neurosciences

(Click title to open job details in a new window.)
Description:

The University of Arizona College of Medicine – Phoenix is seeking an inaugural Chair for its new Department of Translational Neurosciences (TNS). TNS will be a novel medical school department, one that actively bridges basic science and clinical medicine through innovative collaborative research programs. The Chair will have the opportunity to create the overarching vision and, through strategic leadership, to build a center of translational neuroscience excellence. The Department Chair will have resources to recruit TNS faculty who will enhance our University of Arizona Health Sciences (UAHS) scientific community. We seek a visionary leader with expertise in molecular, cellular, or genetic approaches to neuroscience whose research is motivated by the challenges of nervous system disorders and directed toward advancing clinical care and improving human health in the foreseeable future.


Of particular interest for the Chair of TNS position are applicants with any of the following:


*Research portfolio focused on molecular, cellular, and/or genetic approaches to neuroscience. Examples of foci include: Neurodevelopmental disorders, Neuropsychiatric disorders, Disorders of the aging brain

*Expertise in use of cutting-edge technologies, including, but not exclusive to, patient-specific iPSC lines, CRISPR-Cas9, and in vivo brain imaging.

*Development and use of new animal models for disorders of the nervous system.

*Expertise in drug discovery or device development, including advancing to clinical trials.

*Knowledge of intellectual property issues in biomedical research (e.g., patent applications, working with industry partners).

*History of productive collaborations with both physicians and basic scientists.

For physician candidates, clinically active in specialty.


Link: https://uacareers.com/postings/26190
Employer: University of Arizona College of Medicine
Location: Phoenix, AZ
Sector: Academia
Degree required: PhD and/or MD
Conditions: NDG
Job posted: April 2nd, 2018
University of Arizona College of MedicinePhoenix, AZPhD and/or MDNDGApr 02, 2018
Postdoctoral Fellow, Durham Lab

Postdoctoral Fellow, Durham Lab

(Click title to open job details in a new window.)
Description:

A postdoctoral position in ALS research is available in the laboratory of Dr. Heather Durham in the Rare Neurological Diseases Group at the Montreal Neurological Institute, McGill University, Montreal QC Canada. The project involves investigating the role of chromatin remodeling as a convergent mechanism in ALS and in neuronal stress responses (see https://www.ncbi.nlm.nih.gov/pubmed/28973294). The work would include investigation of epigenetic mechanisms in primary culture models, mouse models and post-mortem tissue as well as participation in a drug study in mouse and tissue culture models of ALS. This multidisciplinary project is funded by MDA and by an ALS Canada-Brain Canada Hudson Translational Team Grant involving collaborators with complementary expertise at other Canadian universities.


Applicants are expected to have a PhD in a relevant biomedical field; to be able to work independently as well as a team member, and to bring a passionate interest in working together to understand the pathogenesis of ALS and to find effective treatment. Expertise in epigenetics, stress responses, molecular biology, biochemical assays, mouse models and tissue processing/histochemical techniques are examples of useful experience to complement our team.


To apply for this position, contact Dr Heather Durham.


The Montreal Neurological Institute and Hospital – The Neuro (http://www.mcgill.ca/neuro/), is a world-leading destination for brain research and advanced patient care. Since its founding in 1934 by renowned neurosurgeon Dr. Wilder Penfield, The Neuro has grown to be the largest specialized neuroscience research and clinical centre in Canada, and one of the largest in the world. The seamless integration of research, patient care, and training. The Neuro is home to one of the leading ALS clinics and clinical research units, providing interaction between ALS scientists, clinicians and patients.


 


Employer: McGill University
Location: Montreal, Canada
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: March 30th, 2018
McGill UniversityMontreal, CanadaPhDALSMar 30, 2018
Group Leader, Big Data Neuroscience

Group Leader, Big Data Neuroscience

(Click title to open job details in a new window.)
Description:

Can you develop a productive and innovative research program and establish an independent research group through a combination of core funding and extramural funding? Can you complement the research program of the NIN by working in close collaboration with other research groups at the institute? And do you have a clear vision on how to approach the current challenges in one of the three neuroscience research fields described below? Then this job may be for you.


There is an increasing global collaboration to collect, pool and distribute huge datasets on human genetics, gene expression and brain imaging in order to understand the neurobiological underpinnings of a wide variety of complex traits and phenotypes in health and disease. To bridge these opportunities with current research topics and facilities like the Brain Bank and 7T MRI at the NIN, we are seeking an outstanding scientist who is leading in the innovative use of datasets like the UKBiobank, 23andMe and ENIGMA. The ideal candidate has mathematical, computational, statistical, neurobiological and cognitive-behavioral expertise, as well as technological skills for cluster computing.


Applications should be submitted via the online application form, before 30 April 2018:



  • A cover letter and a statement summarizing your research interests and motivation (max 1 page)

  • A curriculum vitae including a complete list of publications and a list of your five best papers

  • Your previous research accomplishments and your future research goals (max 2 pages)

  • The name and email addresses of up to three referees


The pre-selection will be done by a gender-balanced panel of peers from the institute.


For further information you can look at our website: nin.nl or contact Pieter Roelfsema p.roelfsema@nin.knaw.nl, General Director, Ronald van der Neut r.van.der.neut@nin.knaw.nl, Managing director, or Dorien Bisselink d.bisselink@nin.knaw.nl, head human resources department.


Link: https://www.academictransfer.com/employer/KNAW/vacancy/46229/lang/en/
Employer: Netherlands Institute for Neuroscience
Location: Amsterdam, Netherlands
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 28th, 2018
Applications close: April 29th, 2018
Netherlands Institute for NeuroscienceAmsterdam, NetherlandsPhDNDGMar 28, 2018
Postdoctoral Fellow, Van Damme Lab

Postdoctoral Fellow, Van Damme Lab

(Click title to open job details in a new window.)
Description:

The Laboratory of Neurobiology is part of the research group Experimental Neurology (Neuroscience Department) at KU Leuven. The group has a close collaboration with the Neurology Department of the University Hospitals Leuven with about 50 researchers in different domains.


In addition, the laboratory is one of the research groups of the VIB Center for Brain & Disease Research (CBD) at KU Leuven/ Campus Gasthuisberg focusing on Neuroscience. There are 17 research groups within the CBD with a total employment of 300 researchers (38 different nationalities).


The Laboratory focusses on clinical and fundamental research into the prevention, heredity, the pathogenesis and treatment of neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Charcot-Marie-Tooth Disease (CMT) and stroke.


We are looking for a highly motivated doctoral researcher with interest in neurodegeneration and experience in progranulin biology and/or iPSC technology. Motivated candidates with a strong commitment to basic research are invited to apply.


The research project, under supervision of principal investigator Philip Van Damme, will focus on the neurodegenerative disorders ALS and FTD and will involve in vitro techniques, validation of neuroprotective compounds, iPSCs and small animal models.


Applications should be submitted through the VIB website. Please complete the online application procedure and include a CV, a list of publications if applicable, a summary of past research and the contact information of 2 to 3 referees. The best-ranked candidates will be invited for an interview.


For additional information concerning this job offer, please contact Lien Houbrechts.


Link: https://www.nature.com/naturejobs/science/jobs/640803-phd-position-on-ipsc-models-in-neurodegeneration-als-and-frontotemporal-dementia
Employer: VIB
Location: Leuven, Belgium
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: March 27th, 2018
Applications close: May 27th, 2018
VIBLeuven, BelgiumPhDALS, FTDMar 27, 2018
Neuropathologist, Physician Scientist, Neurodegenerative Disease

Neuropathologist, Physician Scientist, Neurodegenerative Disease

(Click title to open job details in a new window.)
Description:

The Department of Pathology at Northwestern University Feinberg School of Medicine seeks a full-time Assistant Professor, Associate Professor or Professor on the tenure track. Qualified candidates will be physician-scientists MD or MD, PhD, and be Board-certified in Neuropathology. They are expected to develop a federally funded, independent research program in the area of neurodegeneration and engage in collaborations with other researchers who study neurodegenerative diseases throughout Northwestern University.


Service responsibilities include participation in diagnostic neuropathology, which could include surgical, autopsy or neurodegenerative neuropathology, depending on the applicant’s career goals. There will be ample opportunities for mentoring and teaching graduate students, medical students and resident/fellows, as well as for service on department, school or university committees. Qualified candidates will become a leader of the Neuropathology Core of the federally funded Cognitive Neurology and Alzheimer’s Disease Center.


The environment for hypothesis driven basic research, and for translational and collaborative research at Northwestern University and the Northwestern Memorial Hospital is outstanding. Interested applicants should submit a letter of interest, curriculum vitae, and names of three to five references via Northwestern University’s Faculty Recruiting Website.


Daniel J. Brat MD, PhD

Magerstadt Professor and Chairman

Department of Pathology

Northwestern University

Feinberg School of Medicine

303 East Chicago Avenue, Suite 3-140

Chicago, Illinois 60611


Link: https://jobs.sciencecareers.org/job/477324/neurodegenerative-neuropathologist-physician-scientist/
Employer: Northwestern University
Location: Chicago, IL
Sector: Academia
Degree required: MD or MD/PhD, and Board-certified in Neuropathology
Conditions: NDG
Job posted: March 26th, 2018
Northwestern UniversityChicago, ILMD or MD/PhD, and Board-certified in NeuropathologyNDGMar 26, 2018
Assistant, Associate or Full Professor, Molecular Pharmacology & Physiology

Assistant, Associate or Full Professor, Molecular Pharmacology & Physiology

(Click title to open job details in a new window.)
Description:

The Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine invites applications for tenure-track faculty positions at the Assistant/Associate/Full Professor levels. A doctoral degree in medical or biomedical sciences is required. Applicants must demonstrate a strong record of academic accomplishments with NIH-supported research programs. Expertise in neuroscience, cardiovascular, splanchnic organ system, metabolism and inflammation/immunology research areas is preferred, with an emphasis on the study of molecular, cellular and systemic mechanisms. Applicants must also demonstrate a history of medical school teaching excellence and are expected to have outstanding verbal communication skills.


Candidates should send their curriculum vitae that include previous and current research funding, teaching experience, a statement of research plans, and the names/contact information of three references in a single PDF to: Victoria Mothershed at vmothershed@health.usf.edu.


Link: https://jobs.sciencecareers.org/job/477224/assistant-associate-full-professor/
Employer: University of South Florida
Location: Tampa, FL
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 22nd, 2018
University of South FloridaTampa, FLPhDNDGMar 22, 2018
Postdoctoral Fellow, Mueller Lab

Postdoctoral Fellow, Mueller Lab

(Click title to open job details in a new window.)
Description:

We seek a talented and motivated postdoc to join the laboratory of Dr Christian Mueller in the Horae Gene Therapy Center at the University of Massachusetts Medical School. Our dynamic and collaborative research environment at UMMS includes world renowned clinicians and scientists. Additionally, our location close to Boston supports many collaborations with academic and industrial research groups.


Open positions include:  CNS Lead. Responsible for advancing the lab’s preclinical programs for CNS diseases. Lead indications are SOD1, C9orf72-linked amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD). Projects will include early stage research on genome editing for ALS, an IND-enabling study in non-human primates for a gene therapy candidate for ALS, and an IND-enabling study in non-human primates for a gene therapy candidate for HD.


Required Qualifications:

Applicants should have a PhD in biomedical sciences with a strong background in molecular biology and biochemistry, as well a track record in the field of ALS/CNS disorders (CNS Lead role) or liver diseases (Liver Lead role). Hands-on experience with relevant mouse models as well as excellent knowledge of CRISPR-based genome editing are required. Ability to work independently in a fast-paced research environment and multitask, be highly organized and adaptable are required. Strong writing, verbal and interpersonal skills are required.


Required skills:

• PhD degree in biomedical sciences

• track record in ALS/CNS disorders or liver diseases with at least two first author publications

• hands-on experience with genetic mouse models (CNS or liver)

• excellent knowledge of CRISPR-based gene editing

• excellent communication skills both oral and written are essential

Preferred skills

• hands-on experience with CRISPR-based gene editing

• experience in next generation sequencing and bioinformatics

• experience in tissue culture, cytokine multiplex assays and ELISA

Additional Information:

Our lab is multicultural and supports personal development and work-life balance. Attractive salary and benefits available based upon relative working experience.


For more information on the Mueller Lab for Gene Therapy we invite you to visit our website: www.umassmed.edu/muellerlab

Interested candidates please email CV to: Chris.Mueller@umassmed.edu


Link: https://www.indeed.com/viewjob?jk=529c3289cc30c894&tk=1c9a9vpkj0keo44e&from=serp&vjs=3
Employer: University of Massachusetts Medical Center
Location: Worcester, MA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: March 21st, 2018
University of Massachusetts Medical CenterWorcester, MAPhDALSMar 21, 2018
Postdoctoral Fellow, Kalra Lab

Postdoctoral Fellow, Kalra Lab

(Click title to open job details in a new window.)
Description:

Postdoctoral positions are available in the ALS Neuroimaging Research Unit at the University of Alberta. The mission of the lab is to further our understanding of the biology of amyotrophic lateral sclerosis (ALS) using advanced MRI methods. The lab is directed by Dr. Sanjay Kalra, a neurologist and researcher, and the director of the Canadian ALS Neuroimaging Consortium (CALSNIC).


Areas of investigation include 1) Modeling of multimodal MRI data to quantify and characterize cerebral degeneration, 2) Development of novel image analysis methods as potential biomarkers, and 3) Ex-vivo validation of MRI metrics.


Qualifications:


• A PhD or equivalent in a relevant discipline such as computer science, biomedical or electrical engineering, medical physics, or neuroscience


• Experience with image analysis methods and tools (MATLAB, Unix, FSL, etc)


• Familiarity with DTI, structural and functional connectivity, magnetic resonance spectroscopy, cortical thickness estimation, or ex-vivo imaging is an asset


• Highly motivated and able to work collaboratively in a multidisciplinary environment


• Good written and verbal communication skills in English


Interested individuals should forward a CV and list of references with their email addresses to: Sanjay Kalra, MD FRCPC Professor, Department of Medicine University of Alberta sanjay.kalra@ualberta.ca


Link: http://www.alsresearchforum.org/wp-content/uploads/PDF-Kalra.pdf
Employer: University of Alberta
Location: Alberta, Canada
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: March 19th, 2018
University of AlbertaAlberta, CanadaPhDALSMar 19, 2018
Senior Research Investigator

Senior Research Investigator

(Click title to open job details in a new window.)
Description:

The Gene Therapy Program (GTP) and Orphan Disease Center (ODC) are entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases. Our R&D organization has a translational infrastructure that includes: technology discovery, specialized immunology assays operating under GLP, a Vector Core/Manufacturing unit that conducts GMP comparable work, and a large non-clinical program for animal testing under GLP including large NHP and rodent vivaria.


We are currently looking for Senior Research Investigator (SRI), Translational Research, to work in one of several therapeutic areas such as motor neuron, neurodegenerative, and/or therapeutic antibodies.

As a SRI, Translational Research, you will be involved in translation research projects in one or more therapeutic areas. In each case, you will be working in the setting of large interdisciplinary teams, where you will function independently in the execution of the experiments but will need to work collaboratively with other team members. Working independently, you will perform design, optimization and implementation of complex in vitro and in vivo experiments in rodents and NHP within specified timelines; provide cross-organizational support for the essential laboratory functions, including effective management of laboratory resources, and participation in maintenance of centralized reagents; contribute to writing/reviewing manuscripts, preparing presentations, establishing collaborations as well as writing/reviewing protocols and SOPs.


This position offers the opportunity to interface broadly internally & externally with diverse functional areas. Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures.

As a top candidate for this role, you will possess: Minimum of 5 years of experience after the completion of the PhD degree in the field of molecular biology, virology,biochemistry, enzymology, gene therapy, protein engineering, or related fields required.


Candidate must thrive in a team environment, have excellent written and oral communication skills, ability to prioritize in a fast-paced environment, and proficiency with standard methods of data analyses


Link: https://www.linkedin.com/jobs/view/308194466/
Employer: University of Pennsylvania
Location: Philadelphia, PA
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: March 19th, 2018
University of PennsylvaniaPhiladelphia, PAPhDALSMar 19, 2018
Full Professor, RNA Biology

Full Professor, RNA Biology

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Description:

A full professorship position (University of Vienna) is available for an outstanding scientist working on an innovative topic in the area of RNA Biology. The research questions and approaches should include a strong focus on biochemical mechanisms.


This position will include an internationally competitive salary and research package. It will be located at the Max F. Perutz Laboratories (MFPL, www.mfpl.ac.at), a joint venture of the University of Vienna and the Medical University of Vienna, dedicated to top-level biological and medical research. MFPL is home to many highly active research groups, covering Biochemistry and Biophysics; Developmental Biology; Molecular Mechanisms of Disease; Evolution; Genetics, Epigenetics and Gene Regulation, Immunology and Pathogens; Molecular Cell Biology; Neuroscience; Nucleus and Chromosome Biology; RNA Biology; Structural and Computational Biology/ Bioinformatics (http://www.mfpl.ac.at/research/research-areas.html).


The institute is embedded in the Vienna BioCenter (VBC) Campus (http://www.viennabiocenter.org/), provides access to state of the art facilities (http://www.viennabiocenter.org/sites/reseach_education/vbcf.html) and several additional joint activities, such as seminars and researcher training.


Application procedure:


For details on the application procedure and required documents, please see: www.mfpl.ac.at/index.php


Please e-mail your application (preferably as single PDF) to the scientific director Prof. Arndt von Haeseler: rnaprof@mfpl.ac.at


Reference no.: MFPL_RNA-Bio2018


Link: https://www.nature.com/naturejobs/science/jobs/639307-full-professor-position-in-rna-biology
Employer: University of Vienna
Location: Vienna, Austria
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 15th, 2018
Applications close: April 15th, 2018
University of ViennaVienna, AustriaPhDNDGMar 15, 2018
Postdoctoral Fellow, Da Cruz Lab

Postdoctoral Fellow, Da Cruz Lab

(Click title to open job details in a new window.)
Description:

The Da Cruz laboratory focuses on disease mechanisms and therapy development for human neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), the second most common dementia. The laboratory combines sophisticated mouse genetics, cutting-edge stem cell and genome editing approaches to model human neurological disorders in vitro.


We have an NIH-funded position for a Postdoctoral Fellow to advance our studies in elucidating the mechanisms underlying neurodegeneration and muscle denervation in patient-derived neurons and muscle cells. We are keen to attract highly motivated, creative and collaborative applicants with deep experience in cell culture and molecular biology techniques. Solid background on mouse models would be advantageous.


Our salary and benefits package will be highly competitive and commensurate with the cost of living. The Ludwig Institute for Cancer Research is an Equal Opportunity Employer. Please email a cover letter, your CV, and contact details for three references to Sandrine Da Cruz, PhD (sdacruz@ucsd.edu).


Link: http://www.alsresearchforum.org/wp-content/uploads/Da-Cruz-lab-postdoc-position-posting-FINAL.pdf
Employer: University of California
Location: San Diego, CA
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: March 10th, 2018
University of CaliforniaSan Diego, CAPhDALS, FTDMar 10, 2018
Assistant Professor, Pharmacology and Chemical Biology

Assistant Professor, Pharmacology and Chemical Biology

(Click title to open job details in a new window.)
Description:

Beginning immediately, we seek investigators who will develop independent and vigorous research programs in any area of pharmacology and chemical biology. Individuals with demonstrated research interests and accomplishments in chemical biology, molecular pharmacology, systems pharmacology, as well as innovative approaches for therapeutic discovery and disease biology are encouraged to apply.


The successful candidates will join a vibrant and collegial basic research department with extensive scientific connectivity with clinical departments and divisions across the campus, including the Winship Cancer Institute, Dept of Chemistry, Dept of Pediatrics, Dept of Medicine, Dept of Hematology and Medical Oncology, Dept of Neurology, Center for Neurodegenerative Diseases, and other research units of the School of Medicine. New faculty will have immediate access to powerful research infrastructures and core facilities, including the well-recognized Emory Chemical Biology Discovery Center with state-of-the-art high-throughput screening capabilities as well as a top-ranked graduate training program in pharmacology. The Department of Pharmacology at Emory is experiencing another phase of growth with the strong commitment of the leadership of the Woodruff Health Science Center and the School of Medicine, who share a focused vision for therapeutic innovation and translational biology.


Candidates must have a Ph.D., M.D., or equivalent degree in a relevant field of study, postdoctoral experience, and a demonstrated record of research excellence. Applicants should submit (i) a cover letter, (ii) a curriculum vitae, (iii) a brief statement of past research accomplishments, future research interests and goals, and teaching interest (less than 3 pages), and (iv) names and contact information for three references, in one pdf file to Dr. Stephen Traynelis, chair of the Search Committee, c/o Tanisha Haynes at pharmsearch@emory.edu . Applicants should also arrange for three letters of reference to be sent directly to the above e-mail address. For best consideration, apply by April 9, 2018.


Link: https://www.nature.com/naturejobs/science/jobs/638869-assistant-professor-positions-in-pharmacology-and-chemical-biology
Employer: Emory University
Location: Atlanta , GA
Sector: Academia
Degree required: PhD or MD
Conditions: NDG
Job posted: March 9th, 2018
Emory UniversityAtlanta , GAPhD or MDNDGMar 09, 2018
Faculty, Department of Biopharmaceutical Sciences

Faculty, Department of Biopharmaceutical Sciences

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Description:

The University of Illinois at Chicago, College of Pharmacy, Department of Biopharmaceutical Sciences (http://go.uic.edu/BPS) invites applications for an open rank tenure-track faculty position in the field of pharmaceutics, drug delivery, or therapeutic bioengineering. Of particular interest are candidates with training and research interests in the areas of biologics, biopharmaceutical processing, formulation, and delivery. Special attention will be given to candidates whose research complements and expands our research in the areas of cancer, neurodegenerative diseases and/or the human microbiome.


Applicants must have a PhD, or related doctoral degree, as well as postdoctoral training in pharmaceutics, drug delivery, or a related discipline. The ideal candidate will have already established a funded, independent research program, or possess the clear potential to do so, while demonstrating the ability to create and maintain a highly collaborative research team.


Applicants should have significant peer-reviewed publications that demonstrate productivity and the ability to perform cutting edge research. Candidates are expected to establish strong collaborations with department and college faculty. Teaching in the professional and/or graduate programs of the College of Pharmacy is required.

Applicants should complete an online application and attach a cover letter, curriculum vitae, a concise description of research interests and plans, a description of possible departmental and college collaborations, and the contact information for 3 references via the online application process at: https://jobs.uic.edu/job-board/job-details?jobID=92881. Applications via email or fax will not be accepted. Questions may be directed to Richard A. Gemeinhart, Ph.D. (rag@uic.edu), Chair, Search Committee. Review of applications will begin immediately, and the search will remain open until filled. For fullest consideration, submit full application materials by April 16, 2018.


Link: https://jobs.sciencecareers.org/job/476726/open-rank-tenure-track-faculty-position-pharmaceutics-drug-delivery-or-therapeutic-bioengineering/
Employer: University of Illinois
Location: Chicago, IL
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 8th, 2018
University of IllinoisChicago, ILPhDNDGMar 08, 2018
Assistant Professor, Neural Biology

Assistant Professor, Neural Biology

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Description:

The Department of Biological Sciences at Augusta University anticipates a tenure-track position at the rank of Assistant Professor beginning in August 2018. The Department is composed of 22 full-time and 7 part-time faculty members with expertise across a broad spectrum of biological disciplines. We have a strong commitment to providing research opportunities and experience to our undergraduate students in addition to excellent classroom and laboratory instruction. As a thriving unit in this research university, faculty in the Department of Biological Sciences have both the opportunity and the expectation to help develop new undergraduate and graduate programs in the biological sciences. Within the next academic year, we expect to launch our first master’s program in Biomolecular Sciences and the faculty member hired for this position will be an integral part of this emerging program.


Apply online at http:// www.augusta.edu/hr/jobs/faculty. Scroll to the bottom of the screen and click “External applicants can apply for positions at Augusta University, here.” Then, search for the position using the Keywords: Assistant Professor of Biology. Next, click Position Number: 00014526 and attach a single pdf document containing 1. letter of application, 2. curriculum vitae, 3. statement of teaching philosophy, 4. description of current or proposed research project, and 5. graduate transcripts (unofficial copies are acceptable for initial applicant screening). Additionally, please arrange to have three letters of reference sent directly from each author to: Ms. Angie Walton (anwalton@augusta.edu), Office Manager in the Department of Biological Sciences, Augusta University, 1120 15th Street, Augusta GA 30912. Review of applications will begin February 19, 2018 and will continue until the position is filled.


Link: https://neurojobs.sfn.org/jobs/10818413/tenure-track-assistant-professor
Employer: Augusta University
Location: Augusta, GA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 7th, 2018
Augusta UniversityAugusta, GAPhDNDGMar 07, 2018
Research Assistant, Engle Lab

Research Assistant, Engle Lab

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Description:

This is an Exciting opportunity at Boston Children’s Hospital to support a cutting edge developmental neuroscience laboratory using emerging techniques in single cell RNA sequencing (scRNAseq) to understand the molecular mechanisms of motor neuron diseases, including eye movement disorders and amyotrophic lateral sclerosis (ALS). (http://www.childrenshospital.org/research-and-innovation/research/labs/engle-laboratory).


Link: https://main.hercjobs.org/jobs/10824001/research-assistant-i-developmental-neuroscience
Employer: Boston Children's Hospital
Location: Boston, MA
Sector: Academia
Degree required: BS
Conditions: ALS
Job posted: March 7th, 2018
Boston Children's HospitalBoston, MABSALSMar 07, 2018
Bioinformatician, Single Cell Bioinformatics

Bioinformatician, Single Cell Bioinformatics

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Description:

The VIB-KU Leuven Center for Brain & Disease Research is located in Leuven, Belgium, and part of VIB and the University of Leuven (KU Leuven). With more than 300 people working in 17 labs, we study the brain in health and disease. Our research focuses on disorders such as Alzheimer’s, Parkinson’s, frontotemporal dementia and amyotrophic lateral sclerosis (ALS), but also basic research questions relating the cellular heterogeneity of the brain, brain wiring and synapse biology. These studies are integrated with immunology and studies on protein aggregation and amyloid toxicity.


Within our Center, we are seeking a highly motivated Single Cell Bioinformatics Specialist. You will collaborate with the 17 research groups within the Center and provide essential input on computational biology aspects of their research projects. In this job you will be confronted with exciting research questions in neurobiology and neurodegeneration; and with a broad spectrum of computational challenges and single-cell omics data sets. You will work closely with in the Laboratory of Computational Biology (Stein Aerts Lab) and with the single cell expertise unit (Suresh Poovathingal) and you will be part of an active bioinformatics community in Leuven, allowing daily interactions with colleague bioinformaticians.


Link: https://www.nature.com/naturejobs/science/jobs/638647-single-cell-bioinformatics-specialist
Employer: VIB
Location: Ghent, Belgium
Sector: Academia
Degree required: MSc or PhD
Conditions: ALS
Job posted: March 6th, 2018
VIBGhent, BelgiumMSc or PhDALSMar 06, 2018
Research Associate, Medical Machine Learning

Research Associate, Medical Machine Learning

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Description:

The Centre for Health Informatics, Computation and Statistics (CHICAS) at the Lancaster Medical School has an opportunity for a talented machine learning researcher or computational statistician to work on an Academy of Medical Science funded two-year research project into neurodegenerative diseases. As the successful applicant, you will help develop accurate prediction models for patient outcomes in Alzheimer’s disease, motor neuron disease and Parkinson’s disease, based on a combination of clinical, molecular and neuroimaging data.


The project is a collaboration with researchers at the Sheffield Institute for Translational Neuroscience (SITraN), the German Centre for Neurodegenerative Diseases (DZNE) and the Luxembourg Centre for Systems Biomedicine (LCSB). You will have regular interactions with clinical and medical science researchers to discuss ideas and validate findings. The research will lead to a better understanding of variable phenotypes underlying neurodegenerative diseases, as well as resulting in accurate machine learning methods for predicting cognitive and physical decline in patients.


Interviews will take place in April 2018.


Informal inquiries can be made to Dr Frank Dondelinger: f.dondelinger@lancaster.ac.uk


Link: http://www.jobs.ac.uk/job/BIF269/research-associate-in-medical-machine-learning/
Employer: Lancaster University
Location: Lancaster, England
Sector: Academia
Degree required:
Conditions: ALS
Job posted: March 6th, 2018
Applications close: April 4th, 2018
Lancaster UniversityLancaster, EnglandALSMar 06, 2018
Postdoctoral Fellow, MR Imaging

Postdoctoral Fellow, MR Imaging

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Description:

Applications are invited for a 3 year fixed-term Postdoctoral Research Associate position in the Academic Unit of Radiology at the University of Sheffield to develop image analysis techniques for application to a variety of neurological disorders. This is one of three positions that will work within a team of leading imaging scientists, radiologists and their collaborators developing advanced image processing and magnetic resonance imaging techniques. It is expected that there will be some overlap of interests between the posts, providing the successful candidate with the opportunity to collaborate and further broaden their skill base and experience


The post will involve developing and evaluating novel computational MR image analysis methods for application to the range of neurological disorders studied within the Unit. Key applications within the group include the assessment of normal foetal development and foetal brain abnormalities in utero, characterising how these abnormalities manifest through childhood with follow-up imaging, development of methods for quantifying cerebellar abnormalities, imaging of diabetes, epilepsy and cerebral small vessel disease. A wide range of imaging techniques are currently employed to study these diseases, including detailed structural imaging, diffusion imaging, spectroscopy, relaxometry, perfusion imaging (ASL and DSC-MRI) and blood-brain barrier imaging (DCE-MRI). Research will focus on improving the characterisation of brain abnormalities using techniques such as computational modelling, registration, segmentation and machine learning.


The post will particularly suit candidates from an engineering, computer science, mathematics, or physics background with a PhD, or previous postdoctoral experience in biomedical image analysis, or a related area. Experience with any of the MR imaging techniques and their analysis would be advantageous, as would some experience of computer programming. The successful candidate will be encouraged to develop their portfolio of research aligned to one or more of the imaging techniques and application areas depending on their own interests and expertise.


Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVEODg1RkQwNUE3RDQ2NDAxREUmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos#
Employer: University of Sheffield
Location: Sheffield, England
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: March 1st, 2018
Applications close: March 28th, 2018
University of SheffieldSheffield, EnglandPhDNDGMar 01, 2018
Assistant, Associate and Full Professor, Neuroscience

Assistant, Associate and Full Professor, Neuroscience

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Description:

The Department of Neuroscience on the Jupiter, FL campus of The Scripps Research Institute (TSRI) is seeking outstanding applicants for tenure track faculty positions at all levels. We invite applications from ambitious and interactive investigators from all areas of modern neuroscience applying molecular, genetic, biochemical, biophysical, cellular anatomical, and behavioral approaches to elucidate the mechanisms underlying nervous system function and its disorders.


We particularly encourage applications from established investigators; inquiries about opportunities and nominations can be directed to Department Chair Dr. Kirill Martemyanov. Interested candidates should submit their Curriculum Vitae and statement of research interests. Candidates for Assistant Professor level should also include contact information for at least three professional references.


Link: https://jobs.sciencecareers.org/job/476142/faculty-position-tenure-track-neuroscience/?LinkSource=PremiumListing
Employer: Scripps Research Institute
Location: Jupiter, FL
Sector: Academia
Degree required: PhD or MD
Conditions: NDG
Job posted: February 22nd, 2018
Scripps Research InstituteJupiter, FLPhD or MDNDGFeb 22, 2018
Postdoctoral Fellow

Postdoctoral Fellow

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Description:

Applications are invited for the post of Postdoctoral Research Associate within an internationally recognised research group in a vibrant and stimulating environment at the Sheffield Institute for Translational Neuroscience (SITraN).


The post, funded by the Sheffield Institute for Translational Neuroscience (SITraN), will investigate the altered translation of proteins in TDP-43 and C9ORF72 related amyotrophic lateral sclerosis (ALS). It will involve validating predicted data from a newly developed translatome technology using molecular and cellular biology approaches in TDP-43 ALS-inducible cells and human neurons differentiated from reprogrammed ALS-inducible cells and patient fibroblasts including sporadic, TDP-43 and C9ORF72 cases. In addition, the research will involve investigating the biochemical mechanisms of unconventional repeat-associated non-AUG (RAN) translation of C9ORF72 repeat transcripts and its therapeutic attenuation. These investigations will involve biochemical binding assays using recombinant proteins, reporter constructs and in vitro translation assays set up from neuronal cell extracts depleted or not for candidate RAN-associated translation factors.


You should be strongly motivated, self-driven, able to accept direction and be an excellent team player. Good communication, written and interpersonal skills are also essential for this post along with a PhD (or equivalent experience) in

molecular biology, or neuroscience.


Link: https://jobs.shef.ac.uk/sap/bc/webdynpro/sap/hrrcf_a_posting_apply?PARAM=cG9zdF9pbnN0X2d1aWQ9MkQ5RkQ5OUM1NDI1MUVEODg1RjY0MjUxQkM0NUNDMDYmY2FuZF90eXBlPUVYVA%3d%3d&sap-client=400&sap-language=EN&sap-accessibility=X&sap-ep-themeroot=%2fSAP%2fPUBLIC%2fBC%2fUR%2fuos#
Employer: University of Sheffield
Location: Sheffield, England
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: February 22nd, 2018
Applications close: March 18th, 2018
University of SheffieldSheffield, EnglandPhDALSFeb 22, 2018
Postdoctoral Fellow, Meyer Lab

Postdoctoral Fellow, Meyer Lab

(Click title to open job details in a new window.)
Description:

The Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital to move additional programs forward.


Our laboratory is looking for a highly motivated, team-oriented post-doctoral researcher preferably with experience in tissue sectioning and staining methods. The position does not require a background in gene therapy, but experience in working with animals models are an advantage. The candidate works under the mentorship of an established CRI principal investigator or Senior Research Scientists to design experiments and develop protocols to conduct research in the field of gene therapy. From the results of studies, the candidate helps to develop hypotheses for further investigation. Moreover, he/she prepares technical materials such as abstracts, annual reports, scientific papers and presentations. The candidate works toward a goal of becoming independent in his/her research effort, and eventually obtaining external research funding. Appointment as a Post Doc is a maximum of 5 years in length.


Link: https://careerspace.nationwidechildrens.org/ltm/CandidateSelfService/controller.servlet?context.dataarea=ltm&webappname=CandidateSelfService&HROrganization=10&JobReq=17924&JobPost=3&context.session.key.HROrganization=10&context.session.key.JobBoard=EXTERNAL&context.session.key.HROrganization=[Client%20Specific%20Code]&context.session.key.JobBoard=EXTERNAL&context.session.key.HROrganization=[Client%20Specific%20Code]&context.session.key.JobBoard=EXTERNAL#
Employer: Nationwide Children's Hospital
Location: Columbus, OH
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: February 21st, 2018
Nationwide Children's HospitalColumbus, OHPhDALSFeb 21, 2018
Postdoctoral Fellow, Khurana Lab

Postdoctoral Fellow, Khurana Lab

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Description:

One postdoctoral position is available in the Khurana laboratory (khuranalab.bwh.harvard.edu) at Harvard Medical School and Brigham and Women’s Hospital.


The Khurana laboratory uses cutting edge stem cell, genome-editing and in situ proteomic techniques to study the protein-misfolding pathologies that underlie neurodegenerative disease (Chung, Khurana et al. Science 2013; Khurana, Peng, Chung et al. Cell Systems 2017; Khurana and Jarosz Cell 2017).


We now have an opening for a postdoctoral Fellow to push forward our efforts to genetically and physically map interactions of misfolded proteins in patient-derived neurons. We are keen to attract motivated, open-minded and collaborative applicants with experience in advanced cell culture and molecular biology techniques. Human stem cell experience, genome editing experience and solid biochemistry background would be advantageous.


We strive for impactful science in a collaborative and collegial environment. We consider career development in basic science and translational medicine core to our mission. Our postdoctoral fellows will fully benefit from the deep connections to premier academic labs, hospitals and biotech companies that we have established in the extraordinary Boston biomedical environment. The lab is located in the new Building for Transformative Medicine, housing state-of-the-art laboratory and clinical facilities adjacent to Brigham and Women’s Hospital and Harvard Medical School.


Our salary and benefits package will be highly competitive and commensurate with the cost of living. Brigham and Women’s Hospital and Harvard Medical School are Equal Opportunity Employers. Please email a cover letter, your CV, and contact details for three references to Vik Khurana MD PhD (vkhurana@bwh.harvard.edu) and Joan Swan (jhswan@rics.bwh.harvard.edu).


Link: https://www.nature.com/naturejobs/science/jobs/637343-postdoctoral-fellowship
Employer: Brigham and Women's Hospital
Location: Boston, MA
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: February 20th, 2018
Brigham and Women's HospitalBoston, MAPhDNDGFeb 20, 2018
Postdoctoral Fellow, Heutink Lab

Postdoctoral Fellow, Heutink Lab

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Description:

A position for a post-doctoral researcher is available from 01.03.2018 within the scientific team “Genome Biology of Neurodegenerative Diseases” led by Prof. Peter Heutink in Tübingen.


The research focus of our group is to identify genetic risk factors for neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Frontal-Temporal Dementia/Motor Neuron Disease, Progressive Supranuclear Palsy and Ataxia in close collaboration with our clinical partners. As partners in the International Parkinson’s Disease Genomics Consortium (IPDGC) (http://pdgenetics.org/) we participate in large scale genetic studies to identify new genetic risk factors and to characterize the biological consequences of these mutations and risk factors by using automated high-throughput cellular screens combined with genomic and transcriptomic approaches. For further details on the scientific program of the group please refer to http://www.dzne.de/en/sites/tuebingen/research-groups/heutink.html.


Applications should contain the following documents (in English):

·A detailed Curriculum Vitae

·A motivation letter, including a brief description of past research experience and future interests

·Copies of degrees

·Name and contact details of at least two referees


Link: https://jobs.dzne.de/de/jobs/151/postdoctoral-researcher-fm-303720181
Employer: German Center for Neurodegenerative Diseases (DZNE)
Location: Tübingen, Germany
Sector: Academia
Degree required: PhD
Conditions: ALS, FTD
Job posted: February 16th, 2018
German Center for Neurodegenerative Diseases (DZNE)Tübingen, GermanyPhDALS, FTDFeb 16, 2018
Postdoctoral Fellow, Hickman and Shuler Labs

Postdoctoral Fellow, Hickman and Shuler Labs

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Description:

This post doctoral research opportunity focuses combining microfabrication and cell culture to construct in vitro models of the human body or “Body-on-a-Chip” for use in drug development. Multiple organs and their physiological interactions are represented on a single device; these interactions are based on physiologically based pharmacokinetic models. Of particular interest will be to combine metabolically active tissue, such as from the liver, with electrically active tissues such as cardiac myocytes or neuronal cells and then conduct pharmacological studies in this system.


This project is joint between the laboratories of J. Hickman ( UCF ) and Mike Shuler (Cornell) and the student is expected to move between sites as necessary, but will spend the majority of time at UCF . Reimbursement for travel expenses will be provided and the successful candidate will have access to facilities in both universities.


Minimum Qualifications

A bachelor’s degree in an appropriate area of specialization and four years of appropriate experience. Appropriate college coursework may substitute at an equivalent rate for the required experience. If minimum requirements of the position do not require post high school education, an applicant is not required to provide the information on the application.


Additional Minimum Requirements


Preferences

A PhD. in biomedical engineering/pharmacology/material science or related field is expected. Basic knowledge of techniques for microfabrication and/or cell culture is highly desirable. To apply please upload curriculum vitae, a brief description of prior research experience and the names and contact information of three referees to jobswithucf.com


Link: https://www.jobswithucf.com/postings/51294
Employer: University of Central Florida
Location: Orlando, FL
Sector: Academia
Degree required: PhD
Conditions: ALS
Job posted: February 16th, 2018
University of Central FloridaOrlando, FLPhDALSFeb 16, 2018
Research Associate, Meyer Lab

Research Associate, Meyer Lab

(Click title to open job details in a new window.)
Description:

They Meyer laboratory is focusing on research in life-threatening Neurodegenerative and Neurological Disorders such as Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, Rett Syndrome and Batten Disease. We investigate disease mechanisms using state-of-the-art in vitro models and reprogramming techniques. Our efforts are motivated by finding a treatment that can be translated to the clinic. Using gene therapy, we have successfully translated several of our approaches to the clinic and continue to work hand-in-hand with clinicians at the hospital. Our laboratory is looking for a highly motivated, Research Associate with minimum 2 years of experience to join our young and energetic team. The position does not require a background in gene therapy, but experience in performance of ELISAs and ELISpots, or previous experience working in a clinical laboratory, would be of advantage. The candidate will perform research experiments using patient samples, document and maintain exact records of experiments, prepare laboratory reports and assist with analyzing data.


Link: https://careerspace.nationwidechildrens.org/ltm/CandidateSelfService/controller.servlet?context.dataarea=ltm&webappname=CandidateSelfService&HROrganization=10&JobReq=17792&JobPost=3&context.session.key.HROrganization=10&context.session.key.JobBoard=EXTERNAL&context.session.key.HROrganization=[Client%20Specific%20Code]&context.session.key.JobBoard=EXTERNAL&context.session.key.HROrganization=[Client%20Specific%20Code]&context.session.key.JobBoard=EXTERNAL#
Employer: Nationwide Children's Hospital
Location: Columbus, OH
Sector: Academia
Degree required: MS
Conditions: ALS
Job posted: February 16th, 2018
Nationwide Children's HospitalColumbus, OHMSALSFeb 16, 2018
Professor, Neurochemistry

Professor, Neurochemistry

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Description:

The professorship in neurochemistry will be placed at the Department of Biochemistry and Biophysiscs (DBB). Neurochemistry with molecular neurobiology is a predominant area of research and education at the department. Several research groups focus on molecular aspects of neurodegenerative mechanisms, studies of ion channels, neurotoxins, cellular differentiation, intra- and extracellular signal transduction and the blood-brain-barrier. A wide spectrum of analytical methods including biochemistry, bioinformatics, computational chemistry, biophysics and molecular biology are used and developed at the department. Other facilities at DBB include cell culture, MST, NMR, crystallography, cryo-electron microscopy, confocal microscopy and quantitative image analysis.


The environment for research and education within the subject neurochemistry with molecular neuorobiology at Stockholm University also includes scientists at the Department of Molecular Biosciences – The Wenner-Gren Institute and the Department of Zoology. Several research groups within the Department of Biochemistry and Biophysics are located at the Science for Life Laboratory. This is a national facility providing access to advanced methods for large-scale studies of nerve cell development, e.g. via single-cell sequencing and advanced imaging techniques. In addition the proximity to neuroscience departments at Karolinska Institutet, provides ample opportunities for fruitful collaborations. Furthermore, major investments have been and are being made at Stockholm University to create new infrastructures of relevance for neuroscience: a state-of-the-art animal facility with unique opportunities for integrated intravital microscopy, a cryo-EM microscope and the Stockholm University Brain Imaging Centre, an advanced interdisciplinary infrastructure for non-clinical research on brain function and structure.


Further information about the position can be obtained from the Head of the Department, Professor Lena Mäler, telephone: +46 8 16 24 48, lena.maler@dbb.su.se .


For questions regarding the application process, please contact administrator Katarina Gustafsson, telephone: +46 8 16 22 92, katarina.gustafsson@su.se.


Link: https://www.su.se/english/about/working-at-su/jobs?rmpage=job&rmjob=4552
Employer: Stockholm Universität
Location: Stockholm, Sweden
Sector: Academia
Degree required: PhD
Conditions: NDG
Job posted: February 9th, 2018
Applications close: April 23rd, 2018
Stockholm Universität Stockholm, SwedenPhDNDGFeb 09, 2018

Industry

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
NEW! Scientist I, Analytical Development (Small Molecule + ASO)

Scientist I, Analytical Development (Small Molecule + ASO)

(Click title to open job details in a new window.)
Description:

The individual will develop, implement, and qualify innovative analytical solutions for the characterization and testing of ASOs and pharmaceuticals (both off-line and on-line). This work will support process and formulation development and will drive the control strategy. Key areas of focus will be in enhanced impurity monitoring, simple and specific identity testing, and evaluating novel formulations. The primary methods are HPLC/UPLC, MS, and spectroscopy, but the use of other methods is required and should be explored.


The work requires cross-functional interactions and the ability to work independently and creatively to influence stakeholders across the development organization. Excellent technical skills, the ability to think outside of the box, and the ability to drive experiments from proof of concept to implementation are required. The selected individual should be able to clearly communicate their results and accomplishments to a broad audience at team meetings and in written reports. Strong self-motivation and drive to make impactful contributions in a fast-paced environment is critical.


Qualifications


•In-depth knowledge of separation sciences, including (U)HPLC, GC, RP, IC, AEX, and chiral chromatography, and mass spectrometry with extensive laboratory experiences

•Hands-on experience with other characterization techniques such as NMR, Raman, IR, KF, etc.

•Ability to develop and qualify new analytical methods

•Strong problem-solving and troubleshooting skills, capabilities in experimental design and execution, as well ability to work independently are essential.

•Knowledge in drug substance /drug product processing and pharmaceutical sciences as they relate to ASOs and pharmaceuticals

•Knowledge in formulation development and experience in supporting the development of enabling formulations and analyzing drug delivery systems, such as microspheres and liposomes

•Proficient with a wide range of instrumentation platforms, e.g. Empower and ChemStation, and software applications, including Microsoft Office.

•Strong verbal and written communication skills, strong interpersonal skills and the ability to serve as a team member/leader in an environment where individual initiative, collaboration and accountability are valued.


Education


Ph.D. (preferred) in analytical chemistry, chemistry, pharmaceutical sciences, or related discipline with a minimum of 0-3 years experience OR MS Degree with a minimum of 5 years experience.


Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=806754#jobDetails=806754_5140
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: April 13th, 2018
BiogenCambridge, MAPhDNDGApr 13, 2018
Senior Research Associate, Neuroscience

Senior Research Associate, Neuroscience

(Click title to open job details in a new window.)
Description:

Voyager is seeking a highly motivated biologist to contribute to our research team at our facility in Cambridge, Massachusetts. This is an ideal position for an individual with a strong background in in vitro and in vivoexperimental methods, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. The individual will work in the laboratory and be responsible for experimental execution, and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. We are looking for extensive prior hands-on in with techniques such as cell culture, in vitro assay development and execution, CNS tissue preparation, qRT-PCR, western, and ELISA.


This role is located in Cambridge, MA and reports to a Principal Research Scientist.


Requirements



  • B.S. or M.S. in Biology or related discipline

  • Outstanding problem-solving skills

  • Ability to be highly productive in a fluid and fast-paced work environment

  • At least 5 years of hands-on experience with in vitro and in vivotechniques.

  • Experience with design, documentation and execution of experiments

  • Ability to independently analyze and present data to scientific team


Strongly Preferred



  • Working knowledge of AAV, cell culture and cellular biology

  • Familiarity with molecular and cell biology methods

  • Experience with drug discovery for neurodegenerative diseases

  • Experience on cross-functional therapeutic program team

  • Experience within a start-up or small biotech environment


Link: https://www.linkedin.com/jobs/view/597107321/
Employer: Voyager Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: April 5th, 2018
Voyager TherapeuticsCambridge, MABS or MSNDGApr 05, 2018
Scientist I, Biomarkers

Scientist I, Biomarkers

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Description:

The Discovery and Early Development Biomarkers group, part of Biogen’s Research and Early Development department is seeking a highly motivated scientist to join a dynamic team engaged in the discovery and progression of novel biomarkers for neurodegenerative diseases.


Responsibilities include executing experiments to identify, evaluate, and characterize relevant fluid biomarkers that will provide useful pharmacodynamic and efficacy endpoints in either preclinical or clinical settings. The successful candidate will be capable of multitasking and effective planning to consistently meet deadlines. Effective communication and collaboration are crucial.

•Protein biomarker immunoassay development using state of the art immunoassay platforms (i.e. Quanterix Simoa, Singulex Erenna, MSD) or high resolution LC-MS including: Sample preparation (tissues and cell lysates) for protein quantification. Biotinylation and various bead-antibody conjugation techniques. Identification and selection of antibodies for immunoassays. Identification of novel techniques and strategies to enhance assay sensitivity. Recognize and troubleshoot data anomalies to maintain high data quality. Timely recording keeping and data entry into Electronic Lab Notebook. Prepare, review, and deliver scientific presentations for internal/external use. Interact with various project teams as a liaison to share and distribute information. Commitment to help the team achieve deliverables and meet aggressive timelines in a fast-paced environment.


Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=805617#jobDetails=805617_5140
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: March 30th, 2018
BiogenCambridge, MAPhDNDGMar 30, 2018
Biologics Group Leader

Biologics Group Leader

(Click title to open job details in a new window.)
Description:

The Biotechnology Discovery Research (BioTDR) Lead Generation is looking to fill a position for an experienced researcher to lead a drug discovery group passionate about discovering and enablement of large molecule drugs to combat diseases in the immunology, diabetes, oncology, neurodegenerative and pain areas. Are you a highly skilled scientist who has demonstrated ability to facilitate communication between multidisciplinary teams, coordinating complex cross-functional teams? Are you prepared to lead productive collaborations both within BioTDR, and with therapeutic area partners as well as clinical colleagues so as to identify and develop opportunities for protein therapeutics? You will participate in ongoing research projects as well as initiate new drug discovery research efforts. You should be able to work in an interdisciplinary setting, have detailed understanding of disease pathophysiology and drug hunting experience.


Link: https://jobs.sciencecareers.org/job/476801/principal-research-scientist-biologics-group-leader/
Employer: Lilly
Location: Indianapolis, IN
Sector: Industry
Degree required: PhD or MD/PhD or MD
Conditions: NDG
Job posted: March 12th, 2018
LillyIndianapolis, INPhD or MD/PhD or MDNDGMar 12, 2018
Associate Scientist

Associate Scientist

(Click title to open job details in a new window.)
Description:

Yumanity is seeking an associate scientist to join our interdisciplinary team to help advance our novel drug discovery programs. This position will be laboratory based and requires experimental skills in human stem cell culture, including experience differentiating patient and control-derived progenitor cells into various central nervous system cells. This position will report to a Senior Scientist in Discovery Biology and will collaborate across all of Yumanity’s core platforms, including yeast phenotypic screening, target identification and chemistry.


Link: http://www.yumanity.com/careers/
Employer: Yumanity Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 9th, 2018
Yumanity TherapeuticsCambridge, MABS or MSNDGMar 09, 2018
Scientist, Medicinal Chemistry

Scientist, Medicinal Chemistry

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Description:

This lab-based chemist will be a key part of an interdisciplinary team of scientists and will be involved in the design, synthesis, purification, and characterization of novel drugs in the areas of neurodegenerative disease. In this dynamic team focused role, the qualified candidate will also be expected to manage and run the chemistry laboratory, and act as a mentor for junior chemists as needed.


Link: http://www.yumanity.com/careers/
Employer: Yumanity Therapeutics
Location: Cambridge, MA
Sector: Industry
Degree required: BS or MS
Conditions: NDG
Job posted: March 9th, 2018
Yumanity TherapeuticsCambridge, MABS or MSNDGMar 09, 2018
Senior Scientist, ALS

Senior Scientist, ALS

(Click title to open job details in a new window.)
Description:

Sanofi’s Neuroscience Research Therapeutic Area based in Framingham, MA is looking for a highly motivated Sr. Scientist to help identify innovative therapies for amyotrophic lateral sclerosis (ALS). The successful candidate will implement manifold in vitro experimental approaches to investigate the underlying disease biology of ALS and to validate novel therapeutic targets for the treatment of ALS. These techniques include cell culture, molecular biology, biochemistry, immunoblotting, immunohistochemistry, and microscopy. The successful candidate will also use transgenic mouse models to support the in vivo investigation of potential therapeutic approaches.


Link: https://sanofi.wd3.myworkdayjobs.com/en-US/SanofiCareers/job/Framingham-MA/Senior-Scientist--CNS-Genetic-Diseases-Research--Neuroscience-Research-TA_R2448894?src=SNS-10723&source=Linkedin
Employer: Sanofi
Location: Framingham, MA
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: March 9th, 2018
SanofiFramingham, MAPhDALSMar 09, 2018
Research Lead, CNS

Research Lead, CNS

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Description:

The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for:


• Providing leadership within a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.


• Initiate and oversee joint programs with academic collaborators.


• Establishing project timelines and ensuring work is completed according to schedule.


• Training and developing staff at varying levels of experience.


The CNS Preclinical Lead position requires extensive translational experience with CNS gene therapies, including;


• In-depth knowledge of neurodegenerative disorders.


• Experience with delivery techniques targeting the central nervous system such as intracranial injections and have substantial experience with studies in laboratory animals.


• Familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for CNS gene therapy programs.


• Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.


Link: https://neurojobs.sfn.org/jobs/10804598/cns-pre-clinical-research-lead
Employer: Spark Therapeutics
Location: Philadelphia, PA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: March 2nd, 2018
Spark TherapeuticsPhiladelphia, PAPhDNDGMar 02, 2018
Scientist II, CRISPR/Cas Screening

Scientist II, CRISPR/Cas Screening

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Description:

Biogen is seeking an independent and highly motivated scientist to join the Chemical Biology group at the Scientist I/II level. Our group is responsible for identifying novel drug targets from phenotypic screens using cutting edge chemical biology and functional genomic techniques. The primary responsibilities for this position include the application of pooled CRISPR approaches to small molecule target identification in neurodegenerative diseases.

The successful candidate ideally would possess a broad set of skills necessary for compound-sensitized genetic screening including cell-based assay development. Familiarity with unbiased technologies used for target deconvolution and genetic validation is desired. The selected individual will be required to work in cross-functional teams and should be adept at verbal and written communication, innovation, teamwork, and creative problem-solving.


Link: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=800076#jobDetails=800076_5140
Employer: Biogen
Location: Cambridge, MA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: February 19th, 2018
BiogenCambridge, MAPhDNDGFeb 19, 2018
Medical Director

Medical Director

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Description:

Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to the genetics and biology of neurodegeneration and the principles of translational medicine. In anticipation of the Company’s growth plans, Denali Therapeutics is seeking to recruit a Medical Director. The Medical Director will be responsible for design, implementation, monitoring, analysis, and reporting of clinical trials and will provide strategic leadership for development programs.


Link: https://www.denalitherapeutics.com/careers/?gh_jid=954871
Employer: Denali Therapeutics
Location: San Francisco, CA
Sector: Industry
Degree required: MD or MD/PhD, Neurology
Conditions: NDG
Job posted: February 15th, 2018
Denali TherapeuticsSan Francisco, CAMD or MD/PhD, NeurologyNDGFeb 15, 2018
Research Scientist

Research Scientist

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Description:

This scientist will lead an early-stage, hit-to-lead drug development project for Amyotrophic Lateral Sclerosis (ALS). Initially, he or she will conduct in-house experiments and work with external collaborators and CROs to establish a structure-activity relationship and guide the associated medicinal chemistry work. This individual will advance the project into the lead optimization phase, including ADME and in vivo efficacy. The requirements include a PhD in the biomedical sciences, competency in mammalian cell culture and assay development, background in neuroscience research, and industry experience in CNS drug development. Salary will be commensurate with experience; BrainXell offers full health and dental benefits.


Link: https://www.indeed.com/jobs?q=brainxell&l&vjk=df50b84b4e342109
Employer: BrainXell
Location: Madison, WI
Sector: Industry
Degree required: PhD
Conditions: ALS
Job posted: February 15th, 2018
BrainXellMadison, WIPhDALSFeb 15, 2018
Research Scientist, Senior Research Scientist, Biomarkers

Research Scientist, Senior Research Scientist, Biomarkers

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Description:

Denali Therapeutics is seeking to recruit a Research Scientist/Senior Research Scientist in support of the company’s growing translational biology and biomarker needs. This individual will work in close collaboration with colleagues in the In Vivo group, Research, Development Sciences, and Clinical Development to implement biomarker assays in support of preclinical target engagement studies. S/He would also contribute towards discovery/development of novel biomarkers for target engagement assessment and disease biology.


Link: https://www.denalitherapeutics.com/careers/?gh_jid=973466
Employer: Denali Therapeutics
Location: San Francisco, CA
Sector: Industry
Degree required: PhD
Conditions: NDG
Job posted: February 15th, 2018
Denali TherapeuticsSan Francisco, CAPhDNDGFeb 15, 2018

Non-Profit and Government

Job TitleEmployerLocationDegreeConditionsDate Posted ▾
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