Drug Type: Gene Therapy
Mechanism Type: Immunomodulation
Mechanism: TW003 is a vaccine therapy to restore immune balance by targeting the adaptive immune response in ALS. The drug incorporates a patented viral gene delivery platform called SVac. SVac is reported as a safe, highly efficient and nonimmunogenic vector platform.
U.S. Status for ALS: Preclinical
 Treeway Pipeline. Treeway, 2015. Accessed 11 Mar 2016 from http://www.treeway.nl/pipeline.
 Development of ALS therapy by restoring the immune balance. Amarna Therapeutics, 23 Jun 2014. Accessed 11 Mar 2016 from http://www.amarnatherapeutics.com/uploads/Press%20release%20Amarna%20Treeway%20collaboration%20-%20Final.pdf
Last updated March 11th, 2016