Figure 3. Diffusion tensor imaging in the spinal cords of WT and cerebroside sulfotransferase knock-out (CST-KO) mice.
Image credit: Takano, et. al. 2012 under CC BY license

ALS Clinical Trials

Do you know of additional registries of ALS Clinical Trials? Please let us know by emailing us at [email protected].



ALS Therapy Development Institute (ALS TDI) Clinical Trials Database

The ALS TDI maintains an unbiased clinical trials listing which provides information on all those enrolling worldwide. Users are invited to browse trials and subscribe to the clinical trial mailing list to receive email updates on changes to trials listed in this database by clicking on the link above. is an online registry of publicly and privately funded clinical studies. The site is maintained by the National Library of Medicine (NLM) at the National Institutes of Health. The information is updated on the site by the clinical trial sponsor or the principal investigator of the study.  Not all clinical studies in the United States are registered on, since some categories of studies are not required by law to be registered (for example, observational studies that do not study a drug or device).  The registry can be searched for studies on amyotrophic lateral sclerosis, and can be filtered by a variety of fields.

EU Clinical Trials Register

The European Union Clinical Trial Register is a registry of interventional clinical trials conducted in the EU and the European Economic Area, as well as clinical trials from outside the EU/EEA that are related to European pediatric medicine development. The database can be searched for studies on amyotrophic lateral sclerosis, and can be filtered by a variety of fields.

NEALS Clinical Trial Database

The Northeast ALS Consortium (NEALS), in collaboration with the ALS Association provide detailed up-to-date information for finding clinical trials focused on ALS and related motor neuron diseases. The database covers both federally (USA) and privately funded studies and includes interventional trials, examining the efficacy of drugs or treatments and observational trials which aim to gather various information regarding patients and disease progression. Database searches can be filtered by disease status (ALS sporadic/familial, PLS, HSP, healthy with/without ALS family history) and by trial’s patient recruitment status.

World Health Organization’s Clinical Trials Search Portal (ICTRP)

The WHO’s search portal provides information and links to clinical trial records of national registries from around the world. The database can be searched by the name of disease/condition (e.g., amyotrophic lateral sclerosis) and/or by the name of a specific drug or type of intervention, and can be filtered by a variety of fields.



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